Co-culture of stromal and erythroleukemia cells in a perfused hollow fiber bioreactor system as an in vitro bone marrow model for myeloid leukemia

Biotechnology and Bioengineering

Volumn 109, Issue 5, 2012, Pages 1248-1258

  Usuludin, Suaidah Binte Mohamed ^a   Cao, Xue ^a   Lim, Mayasari ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Hematopoietic co culture; Hollow fiber bioreactor; Leukemia; Stromal cell

Indexed keywords

ADHERENT CELLS; BIOPROCESSES; BONE MARROW MICROENVIRONMENT; BONE MARROW MODELS; CELL FUNCTIONS; CELL-CELL CONTACT; CO-CULTURE SYSTEM; COCULTURE; ERYTHROID MATURATION; ERYTHROLEUKEMIA CELLS; EX VIVO EXPANSION; GLUCOSE CONSUMPTION; HIGH CELL DENSITY; HOLLOW FIBER; HOLLOW FIBER BIOREACTOR; IN-VITRO; K562 CELLS; LEUKEMIA; LEUKEMIC CELLS; MEGAKARYOCYTIC DIFFERENTIATIONS; MYELOID LEUKEMIA; PROTEIN CONCENTRATIONS; STROMAL CELLS; TISSUE CULTURE POLYSTYRENES;

BIOREACTORS; BONE; CELL PROLIFERATION; CYTOLOGY; DISEASES; FIBERS; POLYSTYRENES; THREE DIMENSIONAL; TISSUE CULTURE;

CELLS;

GLUCOSE; POLYSTYRENE; PROTEIN;

ARTICLE; BIOREACTOR; BONE MARROW; CELL COMMUNICATION; CELL DENSITY; CELL DIFFERENTIATION; CELL EXPANSION; CELL MATURATION; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); ERYTHROLEUKEMIA CELL; EXTRACELLULAR SPACE; GLUCOSE INTAKE; HOLLOW FIBER BIOREACTOR; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOPHENOTYPING; IN VITRO STUDY; INOCULATION; MYELOID LEUKEMIA; PROTEIN ANALYSIS; STROMA CELL;

BIOREACTORS; BONE MARROW; COCULTURE TECHNIQUES; GLUCOSE; HUMANS; LEUKEMIA, MYELOID; MODELS, THEORETICAL; ORGAN CULTURE TECHNIQUES; PROTEINS; TUMOR CELLS, CULTURED;

EID: 84858441726     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24400     Document Type: Article

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