Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

Cell Reports

Volumn 7, Issue 1, 2014, Pages 293-305

  Hendel, Ayal ^a   Kildebeck, Eric J ^a   Fine, Eli J ^b   Clark, Joseph T ^a   Punjya, Niraj ^a   Sebastiano, Vittorio ^a   Bao, Gang ^b   Porteus, Matthew H ^a  

^a STANFORD UNIVERSITY   (United States)

^b Emory University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; HEMOGLOBIN BETA CHAIN; INTERLEUKIN 2 RECEPTOR GAMMA; ENDONUCLEASE;

ARTICLE; CCR5 GENE; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA REPAIR; DNA SEQUENCE; DOUBLE STRANDED DNA BREAK; GENE FREQUENCY; GENE LOCUS; GENE TECHNOLOGY; GENETIC PROCEDURES; GENOME EDITING; HBB GENE; HOMOLOGY DIRECTED REPAIR; IL2RG GENE; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; SEQUENCE ANALYSIS; SINGLE MOLECULE REAL TIME SEQUENCING; GENETIC ENGINEERING; GENETIC TRANSFECTION; HUMAN; HUMAN GENOME; K562 CELL LINE; METABOLISM; NUCLEOTIDE REPEAT; PROCEDURES;

DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; ENDONUCLEASES; GENETIC ENGINEERING; GENOME, HUMAN; HUMANS; K562 CELLS; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE ANALYSIS, DNA; TRANSFECTION;

EID: 84898046908     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.02.040     Document Type: Article

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