Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells

Journal of Clinical Investigation

Volumn 125, Issue 11, 2015, Pages 4212-4222

  Hernandez, Amanda L ^a   Kitz, Alexandra ^a   Wu, Chuan ^b   Lowther, Daniel E ^a   Rodriguez, Donald M ^a   Vudattu, Nalini ^a   Deng, Songyan ^a   Herold, Kevan C ^a   Kuchroo, Vijay K ^b   Kleinewietfeld, Markus ^a,d   Hafler, David A ^a,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c YALE NEW HAVEN HOSPITAL   (United States)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CHEMOKINE RECEPTOR CXCR3; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 2; RETINOID RELATED ORPHAN RECEPTOR GAMMA; SERUM AND GLUCOCORTICOID REGULATED KINASE 1; SHORT HAIRPIN RNA; SODIUM CHLORIDE; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET; CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; FOXP3 PROTEIN, MOUSE; IMMEDIATE EARLY PROTEIN; NEUTRALIZING ANTIBODY; PROTEIN SERINE THREONINE KINASE; SALT INTAKE; SERUM-GLUCOCORTICOID REGULATED KINASE; SMALL INTERFERING RNA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL FUNCTION; CONCENTRATION PROCESS; CONTROLLED STUDY; DIET SUPPLEMENTATION; EFFECTOR CELL; ENVIRONMENTAL FACTOR; EXPERIMENTAL COLITIS; GENE SILENCING; GRAFT VERSUS HOST REACTION; HIGH SODIUM INTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MURINE MODEL; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REGULATORY T LYMPHOCYTE; TH17 CELL; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; CD4+ T LYMPHOCYTE; CELL CULTURE; COCULTURE; COLITIS; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; INFLAMMATION; MONONUCLEAR CELL; PHARMACOLOGY; PHYSIOLOGY; REPORTER GENE; RNA INTERFERENCE; SALT INTAKE; SECRETION (PROCESS); TRANSPLANTATION; XENOGRAFT;

ADOPTIVE TRANSFER; ANIMALS; ANTIBODIES, NEUTRALIZING; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; COCULTURE TECHNIQUES; COLITIS; CYTOKINES; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; GENES, REPORTER; GRAFT VS HOST DISEASE; HETEROGRAFTS; HUMANS; IMMEDIATE-EARLY PROTEINS; INFLAMMATION; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; MALE; MICE; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SODIUM CHLORIDE; SODIUM CHLORIDE, DIETARY; T-LYMPHOCYTES, REGULATORY;

EID: 84946781806     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81151     Document Type: Article

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