-
1
-
-
0344299189
-
Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous
-
Bachman, M. F., Kohler, G., Ecabert, B., Mak, T. W., and Kopf, M. (1999). Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous. J. Immunol. 163, 1128-1131.
-
(1999)
J. Immunol.
, vol.163
, pp. 1128-1131
-
-
Bachman, M.F.1
Kohler, G.2
Ecabert, B.3
Mak, T.W.4
Kopf, M.5
-
2
-
-
65549088243
-
IL-17-producing human peripheral regulatory T cells retain suppressive function
-
Beriou, G., Costantino, C.M., Ashley, C. W., Yang, L., Kuchroo, V. K., BaecherAllan, C., and Hafler, D. A. (2009). IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 113, 4240-4249.
-
(2009)
Blood
, vol.113
, pp. 4240-4249
-
-
Beriou, G.1
Costantino, C.M.2
Ashley, C.W.3
Yang, L.4
Kuchroo, V.K.5
BaecherAllan, C.6
Hafler, D.A.7
-
3
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli, E., Sullivan, B., Szabo, S. J., Sobel, R. A., Glimcher, L. H., and Kuchroo, V. K. (2004). Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J. Exp. Med. 200, 79-87.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
4
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., Jeffery, E. W., Hjerrild, K. A., Paeper, B., Clark, L. B., Yasayko, S. A., Wilkinson, J. E., Galas, D., Ziegler, S. F., and Ramsdell, F. (2001). Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27, 68-73.
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
Wilkinson, J.E.7
Galas, D.8
Ziegler, S.F.9
Ramsdell, F.10
-
5
-
-
34548128307
-
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4
-
Brustle, A., Heink, S., Huber, M., Rosenplanter, C., Stadelmann, C., Yu, P., Arpaia, E., Mak, T. W., Kamradt, T., and Lohoff, M. (2007). The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immunol. 8, 958-966.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 958-966
-
-
Brustle, A.1
Heink, S.2
Huber, M.3
Rosenplanter, C.4
Stadelmann, C.5
Yu, P.6
Arpaia, E.7
Mak, T.W.8
Kamradt, T.9
Lohoff, M.10
-
6
-
-
80053164789
-
Regulatory T cellsGATAhaveit
-
Campbell, D. J. (2011). Regulatory T cellsGATAhaveit.Immunity 35, 313-315.
-
(2011)
Immunity
, vol.35
, pp. 313-315
-
-
Campbell, D.J.1
-
7
-
-
79251500661
-
Phenotypical and functional specialization of FOXP3+regulatory T cells
-
Campbell, D.J., and Koch, M.A. (2011). Phenotypical and functional specialization of FOXP3+regulatory T cells. Nat. Rev. Immunol. 11, 119-130.
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 119-130
-
-
Campbell, D.J.1
Koch, M.A.2
-
8
-
-
70049113279
-
CD4+ regulatory T cells control TH17responsesinaStat3-dependent manner
-
Chaudhry, A., Rudra, D., Treuting, P., Samstein, R. M., Liang, Y., Kas, A., and Rudensky, A. Y. (2009). CD4+ regulatory T cells control TH17responsesinaStat3-dependent manner. Science 326, 986-991.
-
(2009)
Science
, vol.326
, pp. 986-991
-
-
Chaudhry, A.1
Rudra, D.2
Treuting, P.3
Samstein, R.M.4
Liang, Y.5
Kas, A.6
Rudensky, A.Y.7
-
9
-
-
79954608612
-
Interleukin10 signaling in regulatory T cells is required for suppression of Th 17 cell mediated inflammation
-
Chaudhry, A., Samstein, R. M., Treuting, P., Liang, Y., Pils, M.C., Heinrich, J. M., Jack, R. S., Wunderlich, F. T., Bruning, J. C., Muller, W., and Rudensky, A. Y. (2011). Interleukin10 signaling in regulatory T cells is required for suppression of Th 17 cell mediated inflammation. Immunity 34, 566-578.
-
(2011)
Immunity
, vol.34
, pp. 566-578
-
-
Chaudhry, A.1
Samstein, R.M.2
Treuting, P.3
Liang, Y.4
Pils, M.C.5
Heinrich, J.M.6
Jack, R.S.7
Wunderlich, F.T.8
Bruning, J.C.9
Muller, W.10
Rudensky, A.Y.11
-
10
-
-
79961158055
-
Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
-
Chung, Y., Tanaka, S., Chu, F., Nurieva, R. I., Martinez, G. J., Rawal, S., Wang, Y. H., Lim, H., Reynolds, J. M., Zhou, X.H., Fan, H.M., Liu, Z.M., Neelapu, S. S., and Dong, C. (2011). Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions. Nat. Med. 17, 983-988.
-
(2011)
Nat. Med.
, vol.17
, pp. 983-988
-
-
Chung, Y.1
Tanaka, S.2
Chu, F.3
Nurieva, R.I.4
Martinez, G.J.5
Rawal, S.6
Wang, Y.H.7
Lim, H.8
Reynolds, J.M.9
Zhou, X.H.10
Fan, H.M.11
Liu, Z.M.12
Neelapu, S.S.13
Dong, C.14
-
11
-
-
79952955744
-
Thetranscription factors Blimp-1 and IRF4 jointly control the differentiation and function of effect or regulatory T cells
-
Cretney, E., Xin, A., Shi, W., Minnich, M., Masson, F., Miasari, M., Belz, G. T., Smyth, G.K., Busslinger, M., Nutt, S.L., and Kallies, A. (2011). Thetranscription factors Blimp-1 and IRF4 jointly control the differentiation and function of effect or regulatory T cells. Nat. Immunol. 12, 304-311.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
Belz, G.T.7
Smyth, G.K.8
Busslinger, M.9
Nutt, S.L.10
Kallies, A.11
-
12
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
Crotty, S. (2011). Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 29, 621-663.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
13
-
-
4644369302
-
Interleukin2 is essential for CD4+CD25+ regulatory T cell function
-
De la Rosa, M., Rutz, S., Dorninger, H., and Scheffold, A. (2004).Interleukin2 is essential for CD4+CD25+ regulatory T cell function. Eur. J. Immunol. 34, 2480-2488.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2480-2488
-
-
De la Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
14
-
-
65249155463
-
TranscriptionfactorFoxo3controlsthemagnitude of T cell immune responses by modulating the function of dendritic cells
-
Dejean, A. S., Beisner, D. R., Ch'en, I. L., Kerdiles, Y. M., Babour, A., Arden, K. C., Castrillon, D. H., Depinho, R. A., and Hedrick, S.M. (2009).TranscriptionfactorFoxo3controlsthemagnitude of T cell immune responses by modulating the function of dendritic cells. Nat. Immunol. 10, 504-513.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 504-513
-
-
Dejean, A.S.1
Beisner, D.R.2
Ch'en, I.L.3
Kerdiles, Y.M.4
Babour, A.5
Arden, K.C.6
Castrillon, D.H.7
Depinho, R.A.8
Hedrick, S.M.9
-
15
-
-
84861039642
-
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells
-
Duhen, T., Duhen, R., Lanzavecchia, A., Sallusto, F., and Campbell, D. J. (2012). Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells. Blood 119, 4430-4440.
-
(2012)
Blood
, vol.119
, pp. 4430-4440
-
-
Duhen, T.1
Duhen, R.2
Lanzavecchia, A.3
Sallusto, F.4
Campbell, D.J.5
-
16
-
-
79958130907
-
Interleukin-12 converts Foxp3+ regulatory T cells to interferongamma-producing Foxp3+ Tcells that inhibit colitis
-
Feng, T., Cao, A. T., Weaver, C. T., Elson, C. O., and Cong, Y. (2011). Interleukin-12 converts Foxp3+ regulatory T cells to interferongamma-producing Foxp3+ Tcells that inhibit colitis. Gastroenterology 140, 2031-2043.
-
(2011)
Gastroenterology
, vol.140
, pp. 2031-2043
-
-
Feng, T.1
Cao, A.T.2
Weaver, C.T.3
Elson, C.O.4
Cong, Y.5
-
17
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J. D., Gavin, M. A., and Rudensky, A. Y. (2003). Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4, 330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
18
-
-
0037120053
-
Interleukin 2 signaling is required for CD4(+) regulatory T cell function
-
Furtado, G. C., Curotto De Lafaille, M. A., Kutchukhidze, N., and Lafaille, J. J. (2002). Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J. Exp. Med. 196, 851-857.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 851-857
-
-
Furtado, G.C.1
Curotto De Lafaille, M.A.2
Kutchukhidze, N.3
Lafaille, J.J.4
-
19
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann, U., Orabona, C., Fallarino, F., Vacca, C., Calcinaro, F., Falorni, A., Cand eloro, P., Belladonna, M. L., Bianchi, R., Fioretti, M. C., and Puccetti, P. (2002). CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat. Immunol. 3, 1097-1101.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
Candeloro, P.7
Belladonna, M.L.8
Bianchi, R.9
Fioretti, M.C.10
Puccetti, P.11
-
20
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota, K., Yoshitomi, H., Hashimoto, M., Maeda, S., Teradaira, S., Sugimoto, N., Yamaguchi, T., Nomura, T., Ito, H., Nakamura, T., Sakaguchi, N., and Sakaguchi, S. (2007). Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. 204, 2803-2812.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
Sugimoto, N.6
Yamaguchi, T.7
Nomura, T.8
Ito, H.9
Nakamura, T.10
Sakaguchi, N.11
Sakaguchi, S.12
-
21
-
-
79959782887
-
Regulatory T cell plasticity: beyond the controversies
-
Hori, S. (2011). Regulatory T cell plasticity: beyond the controversies. Trends Immunol. 32, 295-300.
-
(2011)
Trends Immunol
, vol.32
, pp. 295-300
-
-
Hori, S.1
-
22
-
-
0347785480
-
-
Hori, S., Nomura, T., and Sakaguchi, S. (2003). Control of regulatory T cell development by the transcription factor Foxp3. Science299, 1057-1061.
-
(2003)
Control of regulatory T cell development by the transcription factor Foxp3. Science299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
23
-
-
79952300978
-
Characterization of interleukin17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases
-
Hovhannisyan, Z., Treatman, J., Littman, D. R., and Mayer, L. (2011). Characterization of interleukin17-producing regulatory T cells in inflamed intestinal mucosa from patients with inflammatory bowel diseases. Gastroenterology 140, 957-965.
-
(2011)
Gastroenterology
, vol.140
, pp. 957-965
-
-
Hovhannisyan, Z.1
Treatman, J.2
Littman, D.R.3
Mayer, L.4
-
24
-
-
79954620910
-
Th17 cells express interleukin-10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4+ Tcells inaninterleukin-10-dependentmanner
-
Huber, S., Gagliani, N., Esplugues, E., O'Connor, W. Jr., Huber, F. J., Chaudhry, A., Kamanaka, M., Kobayashi, Y., Booth, C. J., Rudensky, A.Y., Roncarolo, M.G., Battaglia, M., and Flavell, R. A. (2011). Th17 cells express interleukin-10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4+ Tcells inaninterleukin-10-dependentmanner. Immunity 34, 554-565.
-
(2011)
Immunity
, vol.34
, pp. 554-565
-
-
Huber, S.1
Gagliani, N.2
Esplugues, E.3
O'Connor Jr., W.4
Huber, F.J.5
Chaudhry, A.6
Kamanaka, M.7
Kobayashi, Y.8
Booth, C.J.9
Rudensky, A.Y.10
Roncarolo, M.G.11
Battaglia, M.12
Flavell, R.A.13
-
25
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., Cox, T., Yasayko, S. A., and Ramsdell, F. (2003). An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4, 337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
26
-
-
65749103365
-
ThetranscriptionfactorT-betcontrolsregulatory T cell homeostasis and function during type 1 inflammation
-
Koch, M. A., Tucker-Heard, G., Perdue, N. R., Killebrew, J. R., Urdahl, K. B., and Campbell, D. J. (2009). ThetranscriptionfactorT-betcontrolsregulatory T cell homeostasis and function during type 1 inflammation. Nat. Immunol. 10, 595-602.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 595-602
-
-
Koch, M.A.1
Tucker-Heard, G.2
Perdue, N.R.3
Killebrew, J.R.4
Urdahl, K.B.5
Campbell, D.J.6
-
27
-
-
0027521572
-
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W. (1993).Interleukin-10-deficientmice developchronicenterocolitis.Cell 75, 263-274.
-
(1993)
Interleukin-10-deficientmice developchronicenterocolitis. Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
28
-
-
79961151137
-
Foxp3+ follicular regulatory T cells control the germinal center response
-
Linterman, M. A., Pierson, W., Lee, S. K., Kallies, A., Kawamoto, S., Rayner, T. F., Srivastava, M., Divekar, D. P., Beaton, L., Hogan, J. J., Fagarasan, S., Liston, A., Smith, K. G., and Vinuesa, C. G. (2011). Foxp3+ follicular regulatory T cells control the germinal center response. Nat. Med. 17, 975-982.
-
(2011)
Nat. Med.
, vol.17
, pp. 975-982
-
-
Linterman, M.A.1
Pierson, W.2
Lee, S.K.3
Kallies, A.4
Kawamoto, S.5
Rayner, T.F.6
Srivastava, M.7
Divekar, D.P.8
Beaton, L.9
Hogan, J.J.10
Fagarasan, S.11
Liston, A.12
Smith, K.G.13
Vinuesa, C.G.14
-
29
-
-
0037015052
-
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
-
Lohoff, M., Mittrucker, H. W., Prechtl, S., Bischof, S., Sommer, F., Kock, S., Ferrick, D.A., Duncan, G.S., Gessner, A., and Mak, T. W. (2002). Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc. Natl. Acad. Sci. U.S.A. 99, 11808-11812.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11808-11812
-
-
Lohoff, M.1
Mittrucker, H.W.2
Prechtl, S.3
Bischof, S.4
Sommer, F.5
Kock, S.6
Ferrick, D.A.7
Duncan, G.S.8
Gessner, A.9
Mak, T.W.10
-
30
-
-
34247122412
-
Stat3and Stat4directdevelopmentof IL-17-secreting Th cells
-
Mathur, A.N., Chang, H.C., Zisoulis, D. G., Stritesky, G. L., Yu, Q., O'Malley, J. T., Kapur, R., Levy, D. E., Kansas, G. S., and Kaplan, M. H. (2007). Stat3and Stat4directdevelopmentof IL-17-secreting Th cells. J. Immunol. 178, 4901-4907.
-
(2007)
J. Immunol.
, vol.178
, pp. 4901-4907
-
-
Mathur, A.N.1
Chang, H.C.2
Zisoulis, D.G.3
Stritesky, G.L.4
Yu, Q.5
O'Malley, J.T.6
Kapur, R.7
Levy, D.E.8
Kansas, G.S.9
Kaplan, M.H.10
-
31
-
-
84857416489
-
Plasticity of Foxp3(+)Tcells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells
-
Miyao, T., Floess, S., Setoguchi, R., Luche, H., Fehling, H. J., Waldmann, H., Huehn, J., and Hori, S. (2012). Plasticity of Foxp3(+)Tcells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. Immunity 36, 262-275.
-
(2012)
Immunity
, vol.36
, pp. 262-275
-
-
Miyao, T.1
Floess, S.2
Setoguchi, R.3
Luche, H.4
Fehling, H.J.5
Waldmann, H.6
Huehn, J.7
Hori, S.8
-
32
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove, G., Bouladoux, N., Wohlfert, E. A., Hall, J. A., Chou, D., Dos Santos, L., O'brien, S., Blank, R., Lamb, E., Natarajan, S., Kastenmayer, R., Hunter, C., Grigg, M. E., and Belkaid, Y. (2009). Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 31, 772-786.
-
(2009)
Immunity
, vol.31
, pp. 772-786
-
-
Oldenhove, G.1
Bouladoux, N.2
Wohlfert, E.A.3
Hall, J.A.4
Chou, D.5
Dos Santos, L.6
O'brien, S.7
Blank, R.8
Lamb, E.9
Natarajan, S.10
Kastenmayer, R.11
Hunter, C.12
Grigg, M.E.13
Belkaid, Y.14
-
33
-
-
0348110327
-
Critical roles for transcription factor GATA-3 in thymocyte development
-
Pai, S. Y., Truitt, M. L., Ting, C. N., Leiden, J. M., Glimcher, L. H., and Ho, I. C. (2003). Critical roles for transcription factor GATA-3 in thymocyte development. Immunity 19, 863-875.
-
(2003)
Immunity
, vol.19
, pp. 863-875
-
-
Pai, S.Y.1
Truitt, M.L.2
Ting, C.N.3
Leiden, J.M.4
Glimcher, L.H.5
Ho, I.C.6
-
34
-
-
36248976097
-
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivationmediatedapoptosisof effectorCD4+ T cells
-
Pandiyan, P., Zheng, L., Ishihara, S., Reed, J., and Lenardo, M. J. (2007). CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivationmediatedapoptosisof effectorCD4+ T cells. Nat. Immunol. 8, 1353-1362.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1353-1362
-
-
Pandiyan, P.1
Zheng, L.2
Ishihara, S.3
Reed, J.4
Lenardo, M.J.5
-
35
-
-
79955529454
-
Transendocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi, O.S., Zheng, Y., Nakamura, K., Attridge, K., Manzotti, C., Schmidt, E. M., Baker, J., Jeffery, L. E., Kaur, S., Briggs, Z., Hou, T. Z., Futter, C. E., Anderson, G., Walker, L. S., and Sansom, D. M. (2011). Transendocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science 332, 600-603.
-
(2011)
Science
, vol.332
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
Schmidt, E.M.6
Baker, J.7
Jeffery, L.E.8
Kaur, S.9
Briggs, Z.10
Hou, T.Z.11
Futter, C.E.12
Anderson, G.13
Walker, L.S.14
Sansom, D.M.15
-
36
-
-
77957371028
-
Stability of the regulatory T cell lineage in vivo
-
Rubtsov, Y. P., Niec, R. E., Josefowicz, S., Li, L., Darce, J., Mathis, D., Benoist, C., and Rudensky, A. Y. (2010). Stability of the regulatory T cell lineage in vivo. Science 329, 1667-1671.
-
(2010)
Science
, vol.329
, pp. 1667-1671
-
-
Rubtsov, Y.P.1
Niec, R.E.2
Josefowicz, S.3
Li, L.4
Darce, J.5
Mathis, D.6
Benoist, C.7
Rudensky, A.Y.8
-
37
-
-
41549159660
-
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
-
Rubtsov, Y. P., Rasmussen, J. P., Chi, E. Y., Fontenot, J., Castelli, L., Ye, X., Treuting, P., Siewe, L., Roers, A., Henderson, W. R. Jr., Muller, W., and Rudensky, A. Y. (2008). Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28, 546-558.
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
Rasmussen, J.P.2
Chi, E.Y.3
Fontenot, J.4
Castelli, L.5
Ye, X.6
Treuting, P.7
Siewe, L.8
Roers, A.9
Henderson Jr, W.R.10
Muller, W.11
Rudensky, A.Y.12
-
38
-
-
33645075732
-
In vivo sites and cellular mechanisms of T reg cell-mediated suppression
-
Rudensky, A. Y., and Campbell, D. J. (2006). In vivo sites and cellular mechanisms of T reg cell-mediated suppression. J. Exp. Med. 203, 489-492.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 489-492
-
-
Rudensky, A.Y.1
Campbell, D.J.2
-
39
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25) Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M., and Toda, M. (1995). Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
40
-
-
36249024247
-
Regulatory T cells - a brief history and perspective
-
Sakaguchi, S., Wing, K., and Miyara, M. (2007). Regulatory T cells - a brief history and perspective. Eur. J. Immunol. 37, S116-S123.
-
(2007)
Eur. J. Immunol.
, vol.37
-
-
Sakaguchi, S.1
Wing, K.2
Miyara, M.3
-
41
-
-
70349512606
-
Regulatory T cells: how do they suppress immune responses?
-
Sakaguchi, S., Wing, K., Onishi, Y., Prieto-Martin, P., and Yamaguchi, T. (2009). Regulatory T cells: how do they suppress immune responses? Int. Immunol. 21, 1105-1111.
-
(2009)
Int. Immunol
, vol.21
, pp. 1105-1111
-
-
Sakaguchi, S.1
Wing, K.2
Onishi, Y.3
Prieto-Martin, P.4
Yamaguchi, T.5
-
42
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi, S., Yamaguchi, T., Nomura, T., and Ono, M. (2008). Regulatory T cells and immune tolerance. Cell 133, 775-787.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
43
-
-
22344434572
-
IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
-
Sawitzki, B., Kingsley, C. I., Oliveira, V., Karim, M., Herber, M., and Wood, K. J. (2005). IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo. J. Exp. Med. 201, 1925-1935.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1925-1935
-
-
Sawitzki, B.1
Kingsley, C.I.2
Oliveira, V.3
Karim, M.4
Herber, M.5
Wood, K.J.6
-
44
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
Schorle, H., Holtschke, T., Hunig, T., Schimpl, A., and Horak, I. (1991). Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 352, 621-624.
-
(1991)
Nature
, vol.352
, pp. 621-624
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
45
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi, R., Hori, S., Takahashi, T., and Sakaguchi, S. (2005). Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J. Exp. Med. 201, 723-735.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
46
-
-
65549136983
-
Mechanisms of foxp3+ T regulatory cell-mediated suppression
-
Shevach, E. M. (2009). Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 30, 636-645.
-
(2009)
Immunity
, vol.30
, pp. 636-645
-
-
Shevach, E.M.1
-
47
-
-
0029028363
-
Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
-
Suzuki, H., Kundig, T. M., Furlonger, C., Wakeham, A., Timms, E., Matsuyama, T., Schmits, R., Simard, J. J., Ohashi, P. S., Griesser, H., Taniguchi, T., Paige, C. J., and Mak, T. W. (1995). Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science 268, 1472-1476.
-
(1995)
Science
, vol.268
, pp. 1472-1476
-
-
Suzuki, H.1
Kundig, T.M.2
Furlonger, C.3
Wakeham, A.4
Timms, E.5
Matsuyama, T.6
Schmits, R.7
Simard, J.J.8
Ohashi, P.S.9
Griesser, H.10
Taniguchi, T.11
Paige, C.J.12
Mak, T.W.13
-
48
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
-
Takahashi, T., Kuniyasu, Y., Toda, M., Sakaguchi, N., Itoh, M., Iwata, M., Shimizu, J., and Sakaguchi, S. (1998). Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10, 1969-1980.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
49
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton, A. M., and Shevach, E. M. (1998). CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med.188, 287-296.
-
(1998)
J. Exp. Med. 188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
50
-
-
63849183918
-
Identification of IL17-producing FOXP3+ regulatory T cells in humans
-
Voo, K. S., Wang, Y. H., Santori, F. R., Boggiano, C., Arima, K., Bover, L., Hanabuchi, S., Khalili, J., Marinova, E., Zheng, B., Littman, D. R., and Liu, Y. J. (2009). Identification of IL17-producing FOXP3+ regulatory T cells in humans. Proc. Natl. Acad. Sci. U.S.A. 106, 4793-4798.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
Boggiano, C.4
Arima, K.5
Bover, L.6
Hanabuchi, S.7
Khalili, J.8
Marinova, E.9
Zheng, B.10
Littman, D.R.11
Liu, Y.J.12
-
51
-
-
80053130719
-
An essential role of the transcriptionfactorGATA-3forthefunction of regulatory T cells
-
Wang, Y., Su, M. A., and Wan, Y. Y. (2011). An essential role of the transcriptionfactorGATA-3forthefunction of regulatory T cells. Immunity 35, 337-348.
-
(2011)
Immunity
, vol.35
, pp. 337-348
-
-
Wang, Y.1
Su, M.A.2
Wan, Y.Y.3
-
52
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
-
Waterhouse, P., Penninger, J. M., Timms, E., Wakeham, A., Shahinian, A., Lee, K. P., Thompson, C. B., Griesser, H., and Mak, T. W. (1995). Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science 270, 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
-
53
-
-
58149214356
-
GlobalmappingofH3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
-
Wei, G., Wei, L., Zhu, J., Zang, C., HuLi, J., Yao, Z., Cui, K., Kanno, Y., Roh, T. Y., Watford, W. T., Schones, D. E., Peng, W., Sun, H. W., Paul, W. E., O'Shea, J. J., and Zhao, K. (2009).GlobalmappingofH3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity 30, 155-167.
-
(2009)
Immunity
, vol.30
, pp. 155-167
-
-
Wei, G.1
Wei, L.2
Zhu, J.3
Zang, C.4
HuLi, J.5
Yao, Z.6
Cui, K.7
Kanno, Y.8
Roh, T.Y.9
Watford, W.T.10
Schones, D.E.11
Peng, W.12
Sun, H.W.13
Paul, W.E.14
O'Shea, J.J.15
Zhao, K.16
-
54
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R.S., Ramsdell, F., Peake, J., Faravelli, F., Casanova, J. L., Buist, N., Levy-Lahad, E., Mazzella, M., Goulet, O., Perroni, L., Bricarelli, F.D., Byrne, G., Mceuen, M., Proll, S., Appleby, M., and Brunkow, M. E. (2001). X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27, 18-20.
-
(2001)
Nat. Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
Faravelli, F.4
Casanova, J.L.5
Buist, N.6
Levy-Lahad, E.7
Mazzella, M.8
Goulet, O.9
Perroni, L.10
Bricarelli, F.D.11
Byrne, G.12
Mceuen, M.13
Proll, S.14
Appleby, M.15
Brunkow, M.E.16
-
55
-
-
0028784289
-
Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
-
Willerford, D. M., Chen, J., Ferry, J. A., Davidson, L., Ma, A., and Alt, F. W. (1995). Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 3, 521-530.
-
(1995)
Immunity
, vol.3
, pp. 521-530
-
-
Willerford, D.M.1
Chen, J.2
Ferry, J.A.3
Davidson, L.4
Ma, A.5
Alt, F.W.6
-
56
-
-
53749094183
-
CTLA-4 control overFoxp3(+)regulatoryTcellfunction
-
Wing, K., Onishi, Y., Prieto-Martin, P., Yamaguchi, T., Miyara, M., Fehervari, Z., Nomura, T., and Sakaguchi, S. (2008). CTLA-4 control overFoxp3(+)regulatoryTcellfunction. Science 322, 271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
Sakaguchi, S.8
-
57
-
-
80051944092
-
Cell-autonomous and non-autonomous roles of CTLA-4 in immuneregulation
-
Wing, K., Yamaguchi, T., and Sakaguchi, S. (2011). Cell-autonomous and non-autonomous roles of CTLA-4 in immuneregulation.TrendsImmunol. 32, 428-433.
-
(2011)
TrendsImmunol
, vol.32
, pp. 428-433
-
-
Wing, K.1
Yamaguchi, T.2
Sakaguchi, S.3
-
58
-
-
80555136815
-
GATA3 controls Foxp3 regulatory T cell fate during inflammation in mice
-
Wohlfert, E. A., Grainger, J. R., Bouladoux, N., Konkel, J. E., Oldenhove, G., Ribeiro, C. H., Hall, J. A., Yagi, R., Naik, S., Bhairavabhotla, R., Paul, W. E., Bosselut, R., Wei, G., Zhao, K., Oukka, M., Zhu, J., and Belkaid, Y. (2011). GATA3 controls Foxp3 regulatory T cell fate during inflammation in mice. J. Clin. Invest. 121, 4503-4515.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4503-4515
-
-
Wohlfert, E.A.1
Grainger, J.R.2
Bouladoux, N.3
Konkel, J.E.4
Oldenhove, G.5
Ribeiro, C.H.6
Hall, J.A.7
Yagi, R.8
Naik, S.9
Bhairavabhotla, R.10
Paul, W.E.11
Bosselut, R.12
Wei, G.13
Zhao, K.14
Oukka, M.15
Zhu, J.16
Belkaid, Y.17
-
59
-
-
80555133319
-
Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells
-
Wollenberg, I., Agua-Doce, A., HernandEZ, A., Almeida, C., Oliveira, V. G., Faro, J., and Graca, L. (2011). Regulation of the germinal center reaction by Foxp3+ follicular regulatory T cells. J. Immunol. 187, 4553-4560.
-
(2011)
J. Immunol.
, vol.187
, pp. 4553-4560
-
-
Wollenberg, I.1
Agua-Doce, A.2
Hernand, E.Z.A.3
Almeida, C.4
Oliveira, V.G.5
Faro, J.6
Graca, L.7
-
60
-
-
82755184094
-
Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions
-
Yamaguchi, T., Wing, J. B., and Sakaguchi, S. (2011). Two modes of immune suppression by Foxp3(+) regulatory T cells under inflammatory or non-inflammatory conditions. Semin. Immunol. 23, 424-430.
-
(2011)
Semin. Immunol.
, vol.23
, pp. 424-430
-
-
Yamaguchi, T.1
Wing, J.B.2
Sakaguchi, S.3
-
61
-
-
58849124250
-
CCR6regulates the migration of inflammatory and regulatory T cells
-
Yamazaki, T., Yang, X. O., Chung, Y., Fukunaga, A., Nurieva, R., Pappu, B., Martin-Orozco, N., Kang, H. S., Ma, L., Panopoulos, A. D., Craig, S., Watowich, S. S., Jetten, A. M., Tian, Q., and Dong, C. (2008). CCR6regulates the migration of inflammatory and regulatory T cells. J. Immunol. 181, 8391-8401.
-
(2008)
J. Immunol.
, vol.181
, pp. 8391-8401
-
-
Yamazaki, T.1
Yang, X.O.2
Chung, Y.3
Fukunaga, A.4
Nurieva, R.5
Pappu, B.6
Martin-Orozco, N.7
Kang, H.S.8
Ma, L.9
Panopoulos, A.D.10
Craig, S.11
Watowich, S.S.12
Jetten, A.M.13
Tian, Q.14
Dong, C.15
-
62
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T (H) 2 responses
-
Zheng, Y., Chaudhry, A., Kas, A., Deroos, P., Kim, J. M., Chu, T. T., Corcoran, L., Treuting, P., Klein, U., and Rudensky, A. Y. (2009). Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T (H) 2 responses. Nature 458, 351-356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
Deroos, P.4
Kim, J.M.5
Chu, T.T.6
Corcoran, L.7
Treuting, P.8
Klein, U.9
Rudensky, A.Y.10
-
63
-
-
43449135305
-
TGFbeta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
-
Zhou, L., Lopes, J. E., Chong, M. M., Ivanov, Ii, Min, R., Victora, G. D., Shen, Y., Du, J., Rubtsov, Y. P., Rudensky, A. Y., Ziegler, S. F., and Littman, D. R. (2008). TGFbeta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 453, 236-240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
Ivanov, I.4
Min, R.5
Victora, G.D.6
Shen, Y.7
Du, J.8
Rubtsov, Y.P.9
Rudensky, A.Y.10
Ziegler, S.F.11
Littman, D.R.12
-
64
-
-
67049168780
-
Plasticity of CD4(+) FoxP3(+)T cells
-
Zhou, X., Bailey-Bucktrout, S., Jeker, L. T., and Bluestone, J. A. (2009). Plasticity of CD4(+) FoxP3(+)T cells. Curr. Opin. Immunol. 21, 281-285
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 281-285
-
-
Zhou, X.1
Bailey-Bucktrout, S.2
Jeker, L.T.3
Bluestone, J.A.4
|