Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense

Cell Metabolism

Volumn 21, Issue 3, 2015, Pages 493-501

  Jantsch, Jonathan ^a,b   Schatz, Valentin ^a,b   Friedrich, Diana ^a   Schröder, Agnes ^a   Kopp, Christoph ^a   Siegert, Isabel ^a   Maronna, Andreas ^c   Wendelborn, David ^a   Linz, Peter ^a   Binger, Katrina J ^e   Gebhardt, Matthias ^e   Heinig, Matthias ^e,f   Neubert, Patrick ^a   Fischer, Fabian ^a   Teufel, Stefan ^c,d   David, Jean Pierre ^c,d   Neufert, Clemens ^c   Cavallaro, Alexander ^c   Rakova, Natalia ^e   Küper, Christoph ^g   Beck, Franz Xaver ^g   Neuhofer, Wolfgang ^h   Muller, Dominik N ^e   Schuler, Gerold ^c   Uder, Michael ^c   Bogdan, Christian ^a   Luft, Friedrich C ^e,i   Titze, Jens ^a,i   more..

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^f MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^g UNIVERSITY OF MUNICH   (Germany)

^h UNIVERSITY OF HEIDELBERG   (Germany)

ⁱ VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SODIUM; SODIUM CHLORIDE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFAT 5; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL SKIN DISEASE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CUTANEOUS PARAMETERS; CUTANEOUS SODIUM STORAGE; EPIGENETICS; HOST RESISTANCE; HUMAN; HUMAN TISSUE; LEISHMANIA MAJOR; MACROPHAGE; MACROPHAGE ACTIVATION; MICROENVIRONMENT; MOUSE; NONHUMAN; PARASITE CONTROL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN FUNCTION; ANIMAL; DRUG EFFECTS; ENZYME ACTIVATION; LEISHMANIASIS, CUTANEOUS; METABOLISM; PHYSIOLOGY; SKIN;

BACTERIA (MICROORGANISMS); LEISHMANIA MAJOR; MUS; PROTOZOA;

ANIMALS; ANTI-INFECTIVE AGENTS; ENZYME ACTIVATION; HUMANS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MACROPHAGES; MICE; NFATC TRANSCRIPTION FACTORS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SKIN; SODIUM;

EID: 84924259577     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2015.02.003     Document Type: Article

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