Antimicrobial activity and membrane-active mechanism of tryptophan zipper-like β-hairpin antimicrobial peptides

Amino Acids

Volumn 47, Issue 11, 2015, Pages 2385-2397

  Xu, Lin ^a,b   Chou, Shuli ^a   Wang, Jiajun ^a   Shao, Changxuan ^a   Li, Weizhong ^a   Zhu, Xin ^a   Shan, Anshan ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b Heilongjiang Research Inst of   (China)

Author keywords

Antimicrobial peptides; Bactericidal mechanism; Cell selectivity; Tryptophan zipper; Hairpin

Indexed keywords

POLYPEPTIDE ANTIBIOTIC AGENT; TRYPTOPHAN ZIPPER LIKE BETA HAIRPIN ANTIMICROBIAL PEPTIDE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; TRYPTOPHAN;

ALPHA HELIX; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL OUTER MEMBRANE; BETA SHEET; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE INTEGRITY; CELLULAR PARAMETERS; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; COVALENT BOND; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STABILITY; DRUG STRUCTURE; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE SPECTROSCOPY; HEMOLYSIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; SALMONELLA ENTERICA SEROVAR PULLORUM; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; BACTERIUM; CHEMISTRY; GROWTH, DEVELOPMENT AND AGING; SYNTHESIS;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; PROTEIN STRUCTURE, SECONDARY; TRYPTOPHAN;

EID: 84945465583     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-015-2029-7     Document Type: Article

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