Role of lipids in the interaction of antimicrobial peptides with membranes

Progress in Lipid Research

Volumn 51, Issue 2, 2012, Pages 149-177

  Teixeira, Vitor ^a,b   Feio, Maria J ^b   Bastos, Margarida ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b Campus Universitário de Santiago   (Portugal)

Author keywords

Antimicrobial peptide; Cell death; Immunity; Intracellular targets; Mechanism of action; Membrane permeabilization; Membrane topology; Peptide design; Phospholipids; Resistance; Structure activity relationship; Target activity; Therapeutic agents

Indexed keywords

ADENOSINE PHOSPHATE; BACTERIOCIN; BUFORIN II; DEFENSIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; DPK 060; INDOLICIDIN; ISEGANAN; LACTOFERRICIN; LACTOFERRIN; LACTOFERRIN[1-11]; LIPID; MELITTIN; MX 594AN; NISIN; OMIGANAN; OPEBACAN; PEPTIDOGLYCAN RECOGNITION PROTEIN; PERGAMUM; PLACEBO; POLYMYXIN B; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEGRIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULFONAMIDE; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ACNE; ADSORPTION; ALPHA HELIX; AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ATOPIC DERMATITIS; BACTERIAL INFECTION; BETA SHEET; CATHETER INFECTION; CONFORMATIONAL TRANSITION; ELECTROPORATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HYDROPHOBICITY; INFECTION PREVENTION; LIPID BILAYER; LIPID COMPOSITION; LIPID RAFT; MEMBRANE BINDING; MEMBRANE COMPONENT; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MEMBRANE STRUCTURE; MENINGOCOCCEMIA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; OSTEOMYELITIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LIPID INTERACTION; REVIEW; SEPTIC SHOCK; STOMATITIS; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL INFECTIONS; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DRUG RESISTANCE, MICROBIAL; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PHOSPHOLIPIDS; PROTEIN STRUCTURE, SECONDARY;

EID: 84856774559     PISSN: 01637827     EISSN: 18732194     Source Type: Journal    
DOI: 10.1016/j.plipres.2011.12.005     Document Type: Review

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