Synthetic cationic amphiphilic α-helical peptides as antimicrobial agents

Biomaterials

Volumn 32, Issue 8, 2011, Pages 2204-2212

  Wiradharma, Nikken ^a   Khoe, Ulung ^a   Hauser, Charlotte A E ^a   Seow, See Voon ^b   Zhang, Shuguang ^c   Yang, Yi Yan ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Helix; Antimicrobial peptides (AMP); Hemolysis; Membrane lysis; Minimum inhibitory concentration (MIC)

Indexed keywords

ALBICANS; AMPHIPHILICS; ANTI-MICROBIAL ACTIVITY; ANTI-MICROBIAL AGENT; ANTIMICROBIAL PEPTIDE; FOLDING BEHAVIOR; GRAM-POSITIVE BACTERIUM; HELICAL PEPTIDE; HEMOLYSIS; HOST ORGANISM; HUMAN PERIPHERAL BLOOD; HYDROPHOBIC RESIDUES; IMMUNE STIMULATION; INNATE IMMUNE SYSTEMS; MICROBIAL CELLS; MINIMUM INHIBITORY CONCENTRATION; RED BLOOD CELL; SAFETY ASPECTS; SEM; SUBTILIS;

BACTERIA; BLOOD; CONCENTRATION (PROCESS); SCANNING ELECTRON MICROSCOPY; YEAST;

PEPTIDES;

ALPHA INTERFERON; GAMMA INTERFERON; POLYPEPTIDE ANTIBIOTIC AGENT; TUMOR NECROSIS FACTOR ALPHA;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CANDIDA ALBICANS; ERYTHROCYTE; HEMOLYSIS; HYDROPHOBICITY; IMMUNOGENICITY; IMMUNOSTIMULATION; LYSIS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACILLUS SUBTILIS; CANDIDA ALBICANS; CATIONS; CIRCULAR DICHROISM; HEMOLYSIS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RATS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

POSIBACTERIA; RATTUS;

EID: 78651445030     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.11.054     Document Type: Article

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