Discovery of deoxyceramides and diacylglycerols as CD1b scaffold lipids among diverse groove-blocking lipids of the human CD1 system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 48, 2011, Pages 19335-19340

  Huang, Shouxiong ^a   Cheng, Tan Yun ^a   Young, David C ^a   Layre, Emilie ^a   Madigan, Cressida A ^a   Shires, John ^b   Cerundolo, Vincenzo ^c   Altman, John D ^b   Moody, D Branch ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Antigen presentation; Cluster of differentiation 1; Mycobacterium tuberculosis

Indexed keywords

CD1 ANTIGEN; CD1B ANTIGEN; CD1C ANTIGEN; CD1D ANTIGEN; CERAMIDE DERIVATIVE; DEOXYCERAMIDE; DIACYLGLYCEROL; LIPID; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SCAFFOLD PROTEIN; T6 ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CELL MIGRATION; CELL POLARITY; CELL STRAIN HEK293; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELUTION; GENE DELETION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; LYMPHOCYTE DIFFERENTIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; ANTIGENS, CD1; BASE SEQUENCE; CELL LINE; CERAMIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIGLYCERIDES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; SEQUENCE ANALYSIS, DNA;

EID: 82755167981     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112969108     Document Type: Article

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