메뉴 건너뛰기




Volumn , Issue , 2015, Pages 621-647

Marine cyanobacteria compounds with anticancer properties: Implication of apoptosis

Author keywords

Anticancer compounds; Apoptose; Marine cyanobacteria

Indexed keywords


EID: 84944611482     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-319-07145-9_29     Document Type: Chapter
Times cited : (9)

References (130)
  • 1
    • 0032996507 scopus 로고    scopus 로고
    • The spindle checkpoint
    • Amon A (1999) The spindle checkpoint. Curr Opin Genet Dev 9 (1):69-75
    • (1999) Curr Opin Genet Dev , vol.9 , Issue.1 , pp. 69-75
    • Amon, A.1
  • 2
    • 17444379382 scopus 로고    scopus 로고
    • Isolation of swinholide a and related glycosylated derivative from two field collections of marine cyanobacteria
    • Andrianasolo EH et al (2005) Isolation of swinholide A and related glycosylated derivative from two field collections of marine cyanobacteria. Org Lett 7 (7):1375-1378
    • (2005) Org Lett , vol.7 , Issue.7 , pp. 1375-1378
    • Andrianasolo, E.H.1
  • 3
    • 84864590886 scopus 로고    scopus 로고
    • Coibacins a-d, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins
    • Balunas MJ et al (2012) Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Org Lett 14 (15):3878-3881
    • (2012) Org Lett , vol.14 , Issue.15 , pp. 3878-3881
    • Balunas, M.J.1
  • 4
    • 4143108125 scopus 로고    scopus 로고
    • Cd95 ligand induces motility and invasiveness of apoptosis-resis- tant tumor cells
    • Barnhart BC et al (2004) CD95 ligand induces motility and invasiveness of apoptosis-resis- tant tumor cells. Embo J 23 (15):3175-3185
    • (2004) Embo J , vol.23 , Issue.15 , pp. 3175-3185
    • Barnhart, B.C.1
  • 5
    • 0019762804 scopus 로고
    • Leukocyte elastase
    • Barrett AJ (1981) Leukocyte elastase. Methods Enzymol 80:581-588
    • (1981) Methods Enzymol , vol.80 , pp. 581-588
    • Barrett, A.J.1
  • 6
    • 0027536149 scopus 로고
    • Longo, growth inhibition of human lymphoma cell lines by the marine products, dolastatins 10 and 15
    • Beckwith M, Urba WJ, Longo DL (1993) Longo, growth inhibition of human lymphoma cell lines by the marine products, dolastatins 10 and 15. J Natl Cancer Inst 85 (6):483-488
    • (1993) J Natl Cancer Inst , vol.85 , Issue.6 , pp. 483-488
    • Beckwith, M.1    Urba, W.J.2    Longo, D.L.3
  • 7
    • 33845656764 scopus 로고    scopus 로고
    • Structure-activity delineation of quinones related to the biologically active calothrixin b
    • Bernardo PH et al (2007) Structure-activity delineation of quinones related to the biologically active Calothrixin B. Bioorg Med Chem Lett 17 (1):82-85
    • (2007) Bioorg Med Chem Lett , vol.17 , Issue.1 , pp. 82-85
    • Bernardo, P.H.1
  • 8
    • 84867017897 scopus 로고    scopus 로고
    • Viequeamide a, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium
    • Boudreau PD et al (2012) Viequeamide A, a cytotoxic member of the kulolide superfamily of cyclic depsipeptides from a marine button cyanobacterium. J Nat Prod 75(9):1560-1570
    • (2012) J Nat Prod , vol.75 , Issue.9 , pp. 1560-1570
    • Boudreau, P.D.1
  • 10
    • 0000518282 scopus 로고    scopus 로고
    • General characteristics of the cyanobacteria
    • D.R.B.R.W.C, Springer, New York
    • Castenholz RW (2001) General characteristics of the cyanobacteria. In: D.R.B.R.W.C. (Ed) Bergey’s manual of systematic bacteriology. Springer, New York, pp 474-487
    • (2001) Bergey’s Manual of Systematic Bacteriology , pp. 474-487
    • Castenholz, R.W.1
  • 11
    • 33750481912 scopus 로고    scopus 로고
    • Characterization of apoptosis induced by marine natural products in non small cell lung cancer a549 cells
    • Catassi A et al (2006) Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells. Cell Mol Life Sci 63 (19-20):2377-2386
    • (2006) Cell Mol Life Sci , vol.63 , Issue.19-20 , pp. 2377-2386
    • Catassi, A.1
  • 12
    • 80052917694 scopus 로고    scopus 로고
    • Isomalyngamide a, a-1 and their analogs suppress cancer cell migration in vitro
    • Chang TT et al (2011) Isomalyngamide A, A-1 and their analogs suppress cancer cell migration in vitro. Eur J Med Chem 46 (9):3810-3819
    • (2011) Eur J Med Chem , vol.46 , Issue.9 , pp. 3810-3819
    • Chang, T.T.1
  • 13
    • 0042193717 scopus 로고    scopus 로고
    • Human cancer cell (Jurkat) killing by the cyanobacterial metabolite calothrixin a
    • Chen XX, Smith GD, Waring P (2003) Human cancer cell (Jurkat) killing by the cyanobacterial metabolite calothrixin A. J Appl Phycol 15 (4):269-277
    • (2003) J Appl Phycol , vol.15 , Issue.4 , pp. 269-277
    • Chen, X.X.1    Smith, G.D.2    Waring, P.3
  • 14
    • 77956201068 scopus 로고    scopus 로고
    • The hoiamides, structurally intriguing neurotoxic lipopeptides from papua new guinea marine cyanobacteria
    • Choi H et al (2010) The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria. J Nat Prod 73 (8):1411-1421
    • (2010) J Nat Prod , vol.73 , Issue.8 , pp. 1411-1421
    • Choi, H.1
  • 15
    • 84866244960 scopus 로고    scopus 로고
    • Lyngbyabellins k-n from two palmyra atoll collections of the marine cyanobacteriummoorea bouillonii
    • Choi H et al (2012) Lyngbyabellins K-N from two Palmyra Atoll collections of the marine CyanobacteriumMoorea bouillonii. Eur J Org Chem 27:5141-5150
    • (2012) Eur J Org Chem , vol.27 , pp. 5141-5150
    • Choi, H.1
  • 16
    • 84868218952 scopus 로고    scopus 로고
    • Marine cyanobacteria compounds with anticancer properties: A review on the implication of apoptosis
    • Costa M et al (2012) Marine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosis. Mar Drugs 10 (10):2181-2207
    • (2012) Mar Drugs , vol.10 , Issue.10 , pp. 2181-2207
    • Costa, M.1
  • 17
    • 84892877857 scopus 로고    scopus 로고
    • Exploring bioactive properties of marine cyanobacteria isolated from the portuguese coast: High potential as a source of anticancer compounds
    • Costa M et al (2014) Exploring bioactive properties of marine cyanobacteria isolated from the Portuguese coast: high potential as a source of anticancer compounds. Mar Drugs 12(1):98-114
    • (2014) Mar Drugs , vol.12 , Issue.1 , pp. 98-114
    • Costa, M.1
  • 18
    • 84944542442 scopus 로고    scopus 로고
    • Cytotoxicity of marine cyanobacteria extracts on osteosarcoma cells
    • Costa-Rodrigues J et al (2012) Cytotoxicity of marine cyanobacteria extracts on osteosarcoma cells. Bone 50:S181-S182
    • (2012) Bone , vol.50 , pp. S181-S182
    • Costa-Rodrigues, J.1
  • 19
    • 0037850864 scopus 로고    scopus 로고
    • Isolation of homodolastatin 16, a new cyclic depsipeptide from a kenyan collection oflyngbya majuscula
    • Davies-Coleman MT et al (2003) Isolation of homodolastatin 16, a new cyclic depsipeptide from a Kenyan collection ofLyngbya majuscula. J Nat Prod 66 (5):712-715
    • (2003) J Nat Prod , vol.66 , Issue.5 , pp. 712-715
    • Davies-Coleman, M.T.1
  • 21
    • 3042551455 scopus 로고    scopus 로고
    • Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium lyngbya majuscula
    • Edwards DJ et al (2004) Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula. Chem Biol 11 (6):817-833
    • (2004) Chem Biol , vol.11 , Issue.6 , pp. 817-833
    • Edwards, D.J.1
  • 22
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • Elmore S (2007) Apoptosis: a review of programmed cell death. Toxicol Pathol 35 (4):495-516
    • (2007) Toxicol Pathol , vol.35 , Issue.4 , pp. 495-516
    • Elmore, S.1
  • 23
    • 79957982955 scopus 로고    scopus 로고
    • Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus lyngbya
    • Engene N et al (2011) Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya. Environ Microbiol 13 (6):1601-1610
    • (2011) Environ Microbiol , vol.13 , Issue.6 , pp. 1601-1610
    • Engene, N.1
  • 24
    • 84860714868 scopus 로고    scopus 로고
    • Moorea producens
    • Engene N et al (2012) Moorea producens gen. Nov., sp. Nov. And Moorea bouillonii comb. Nov., tropical marine cyanobacteria rich in bioactive secondary metabolites. Int J Syst Evol Microbiol 62(Pt 5):1171-1178
    • (2012) J Syst Evol Microbiol , vol.62 , pp. 1171-1178
    • Engene, N.1
  • 25
    • 78649907427 scopus 로고    scopus 로고
    • Photosynthetic marine organisms as a source of anticancer compounds
    • Folmer F et al (2010) Photosynthetic marine organisms as a source of anticancer compounds. Phytochem Rev 9 (4):557-579
    • (2010) Phytochem Rev , vol.9 , Issue.4 , pp. 557-579
    • Folmer, F.1
  • 26
    • 0028258027 scopus 로고
    • Structure of curacin a, a novel antimitotic, antiproliferative, and brine shrimp toxic natural product from the marine cyanobacterium lyngbya majuscula
    • Gerwick WH et al (1994) Structure of Curacin A, a novel antimitotic, antiproliferative, and brine shrimp toxic natural product from the marine cyanobacterium Lyngbya majuscula. J Org Chem 59:1243-1245
    • (1994) J Org Chem , vol.59 , pp. 1243-1245
    • Gerwick, W.H.1
  • 27
    • 45349092848 scopus 로고    scopus 로고
    • Giant marine cyanobacteria produce exciting potential pharmaceuticals
    • Gerwick WH et al (2008) Giant marine cyanobacteria produce exciting potential pharmaceuticals. Microbe 3:8
    • (2008) Microbe , vol.3 , pp. 8
    • Gerwick, W.H.1
  • 28
    • 0035144142 scopus 로고    scopus 로고
    • Isolation and structure determination of nostocyclopeptides a1 and a2 from the terrestrial cyanobacterium nostoc sp. Atcc53789
    • Golakoti T et al (2001) Isolation and structure determination of nostocyclopeptides A1 and A2 from the terrestrial cyanobacterium Nostoc sp. Atcc53789. J Nat Prod 64 (1):54-59
    • (2001) J Nat Prod , vol.64 , Issue.1 , pp. 54-59
    • Golakoti, T.1
  • 29
    • 4444238267 scopus 로고    scopus 로고
    • The macrophage and the apoptotic cell: An innate immune interaction viewed simplistically?
    • Gregory CD, Devitt A (2004) The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically? Immunology 113 (1):1-14
    • (2004) Immunology , vol.113 , Issue.1 , pp. 1-14
    • Gregory, C.D.1    Devitt, A.2
  • 30
    • 0033179760 scopus 로고    scopus 로고
    • Bcl-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM, Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13 (15):1899-1911
    • (1999) Genes Dev , vol.13 , Issue.15 , pp. 1899-1911
    • Gross, A.1    Mc Donnell, J.M.2    Korsmeyer, S.J.3
  • 31
    • 77956343333 scopus 로고    scopus 로고
    • Two cytotoxic stereoisomers of malyngamide c, 8-epi-malyngamide c and 8-o-acetyl-8-epi-malyngamide c, from the marine cyanobacterium lyngbya majuscula
    • Gross H et al (2010) Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula. Phytochemistry 71 (14-15):1729-1735
    • (2010) Phytochemistry , vol.71 , Issue.14-15 , pp. 1729-1735
    • Gross, H.1
  • 32
    • 45249101364 scopus 로고    scopus 로고
    • Dragonamides c and d, linear lipopeptides from the marine cyanobacterium brown lyngbyapolychroa
    • Gunasekera SP et al (2008) Dragonamides C and D, linear lipopeptides from the marine cyanobacterium brown Lyngbyapolychroa. J Nat Prod 71 (5):887-890
    • (2008) J Nat Prod , vol.71 , Issue.5 , pp. 887-890
    • Gunasekera, S.P.1
  • 33
    • 77950383799 scopus 로고    scopus 로고
    • Molassamide, a depsipeptide serine protease inhibitor from the marine cyanobacterium dichothrix utahensis
    • Gunasekera SP et al (2010) Molassamide, a depsipeptide serine protease inhibitor from the marine cyanobacterium Dichothrix utahensis. J Nat Prod 73 (3):459-462
    • (2010) J Nat Prod , vol.73 , Issue.3 , pp. 459-462
    • Gunasekera, S.P.1
  • 34
    • 47549097980 scopus 로고    scopus 로고
    • Apratoxin d, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria lyngbya majuscula and lyngbya sordida
    • Gutierrez M et al (2008) Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida. J Nat Prod 71 (6):1099-1103
    • (2008) J Nat Prod , vol.71 , Issue.6 , pp. 1099-1103
    • Gutierrez, M.1
  • 35
    • 77951551844 scopus 로고    scopus 로고
    • Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium lyngbya majuscula
    • Gutierrez M et al (2010) Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula. J Nat Prod 73 (4):709-711
    • (2010) J Nat Prod , vol.73 , Issue.4 , pp. 709-711
    • Gutierrez, M.1
  • 36
    • 17444405602 scopus 로고    scopus 로고
    • The wewakpeptins, cyclic depsipeptides from a papua new guinea collection of the marine cyanobacterium lyngbya semiplena
    • Han B et al (2005) The wewakpeptins, cyclic depsipeptides from a Papua new guinea collection of the marine cyanobacterium Lyngbya semiplena. J Org Chem 70 (8):3133-3139
    • (2005) J Org Chem , vol.70 , Issue.8 , pp. 3133-3139
    • Han, B.1
  • 37
    • 27644461429 scopus 로고    scopus 로고
    • Isolation and structure of five lyngbyabellin derivatives from a papua new guinea collection of the marine cyanobacterium lyngbya majuscula
    • Han BN et al (2005) Isolation and structure of five lyngbyabellin derivatives from a Papua new guinea collection of the marine cyanobacterium Lyngbya majuscula. Tetrahedron 61 (49):11723-11729
    • (2005) Tetrahedron , vol.61 , Issue.49 , pp. 11723-11729
    • Han, B.N.1
  • 38
    • 33744460793 scopus 로고    scopus 로고
    • Aurilides b and c, cancer cell toxins from a papua new guinea collection of the marine cyanobacterium lyngbya majuscula
    • Han B et al (2006) Aurilides B and C, cancer cell toxins from a Papua new guinea collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod 69 (4):572-575
    • (2006) J Nat Prod , vol.69 , Issue.4 , pp. 572-575
    • Han, B.1
  • 39
    • 0031668094 scopus 로고    scopus 로고
    • Symplostatin 1: A dolastatin 10 analogue from the marine cyanobacterium symploca hydnoides
    • Harrigan GG et al (1998) Symplostatin 1: a dolastatin 10 analogue from the marine cyanobacterium Symploca hydnoides. J Nat Prod 61 (9):1075-1077
    • (1998) J Nat Prod , vol.61 , Issue.9 , pp. 1075-1077
    • Harrigan, G.G.1
  • 40
    • 0032423408 scopus 로고    scopus 로고
    • Photosynthesis and the origin of life
    • Hartman H (1998) Photosynthesis and the origin of life. Orig Life Evol Biosph 28:515-521
    • (1998) Orig Life Evol Biosph , vol.28 , pp. 515-521
    • Hartman, H.1
  • 41
    • 84878787575 scopus 로고    scopus 로고
    • Coibamide a induces mtor-independent autophagy and cell death in human glioblastoma cells
    • Hau AM et al (2013) Coibamide A induces mTOR-independent autophagy and cell death in human glioblastoma cells. Plos One 8 (6):e65250
    • (2013) Plos One , vol.8 , Issue.6
    • Hau, A.M.1
  • 42
    • 0036239723 scopus 로고    scopus 로고
    • Malevamide d: Isolation and structure determination of an isodol- astatin h analogue from the marine cyanobacterium symploca hydnoides
    • Horgen FD et al (2002) Malevamide D: isolation and structure determination of an isodol- astatin H analogue from the marine cyanobacterium Symploca hydnoides. J Nat Prod 65 (4):487-491
    • (2002) J Nat Prod , vol.65 , Issue.4 , pp. 487-491
    • Horgen, F.D.1
  • 43
    • 0035091868 scopus 로고    scopus 로고
    • New lipopeptides from the caribbean cyanobacterium lyng- bya majuscula
    • Jimenez JI, Scheuer PJ (2001) New lipopeptides from the Caribbean cyanobacterium Lyng- bya majuscula. J Nat Prod 64 (2):200-203
    • (2001) J Nat Prod , vol.64 , Issue.2 , pp. 200-203
    • Jimenez, J.I.1    Scheuer, P.J.2
  • 44
    • 77954679917 scopus 로고    scopus 로고
    • The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria
    • Jones AC et al (2010) The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria. Nat Prod Rep 27 (7):1048-1065
    • (2010) Nat Prod Rep , vol.27 , Issue.7 , pp. 1048-1065
    • Jones, A.C.1
  • 45
    • 0032006059 scopus 로고    scopus 로고
    • Microtubules and actin filaments: Dynamic targets for cancer chemotherapy
    • Jordan MA, Wilson L (1998) Microtubules and actin filaments: dynamic targets for cancer chemotherapy. Curr Opin Cell Biol 10 (1):123-130
    • (1998) Curr Opin Cell Biol , vol.10 , Issue.1 , pp. 123-130
    • Jordan, M.A.1    Wilson, L.2
  • 46
    • 0032950658 scopus 로고    scopus 로고
    • Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: Induction of apoptosis and bcl-2 modification
    • Kalemkerian GP et al (1999) Activity of dolastatin 10 against small-cell lung cancer in vitro and in vivo: induction of apoptosis and bcl-2 modification. Cancer Chemother Pharmacol 43 (6):507-515
    • (1999) Cancer Chemother Pharmacol , vol.43 , Issue.6 , pp. 507-515
    • Kalemkerian, G.P.1
  • 47
    • 0025878872 scopus 로고
    • Comparison of the sulforhodamine b protein and tetrazolium (Mtt) assays for in vitro chemosensitivity testing
    • Keepers YP et al (1991) Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing. Eur J Cancer 27 (7):897-900
    • (1991) Eur J Cancer , vol.27 , Issue.7 , pp. 897-900
    • Keepers, Y.P.1
  • 48
    • 65249155938 scopus 로고    scopus 로고
    • Calothrixins, a new class of human dna topoisomerase i poisons
    • Khan QA, Lu J, Hecht SM (2009) Calothrixins, a new class of human DNA topoisomerase I poisons. J Nat Prod 72 (3):438-442
    • (2009) J Nat Prod , vol.72 , Issue.3 , pp. 438-442
    • Khan, Q.A.1    Lu, J.2    Hecht, S.M.3
  • 49
    • 0028091273 scopus 로고
    • Inhibition of the soluble and tumor cell receptorbound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis
    • Kobayashi H, Shinohara H, Takeuchi K, Itoh M, Fujie M, Saitoh M and Terao T (1994) Inhibition of the soluble and tumor cell receptorbound plasmin by urinary trypsin inhibitor and subsequent effects on tumor cell invasion and metastasis. Cancer Res 54 (3): 844-849
    • (1994) Cancer Res , vol.54 , Issue.3 , pp. 844-849
    • Kobayashi, H.1    Shinohara, H.2    Takeuchi, K.3    Itoh, M.4    Fujie, M.5    Saitoh, M.6    Terao, T.7
  • 50
    • 69449095860 scopus 로고    scopus 로고
    • Caspases and kinases in a death grip
    • Kurokawa M, Kornbluth S (2009) Caspases and kinases in a death grip. Cell 138 (5):838-854
    • (2009) Cell , vol.138 , Issue.5 , pp. 838-854
    • Kurokawa, M.1    Kornbluth, S.2
  • 51
    • 70349203850 scopus 로고    scopus 로고
    • Grassystatins a-c from marine cyanobacteria, potent cathepsin
    • Kwan JC et al (2009) Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation. J Med Chem 52 (18):5732-5747
    • (2009) E Inhibitors that Reduce Antigen Presentation. J Med Chem , vol.52 , Issue.18 , pp. 5732-5747
    • Kwan, J.C.1
  • 52
    • 75149193409 scopus 로고    scopus 로고
    • Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium lyngbya semiplena
    • Kwan JC et al (2009) Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena. Mar Drugs 7 (4):528-538
    • (2009) Mar Drugs , vol.7 , Issue.4 , pp. 528-538
    • Kwan, J.C.1
  • 53
    • 84880832018 scopus 로고    scopus 로고
    • Antitumor activity of hierridin b, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains
    • Leao PN et al (2013) Antitumor activity of Hierridin B, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains. Plos One 8 (7):e69562
    • (2013) Plos One , vol.8 , Issue.7
    • Leao, P.N.1
  • 54
    • 39049108641 scopus 로고    scopus 로고
    • Symplocamide a, a potent cytotoxin and chymotrypsin inhibitor from the marine cyanobacterium symploca sp
    • Linington RG et al (2008) Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. J Nat Prod 71 (1):22-27
    • (2008) J Nat Prod , vol.71 , Issue.1 , pp. 22-27
    • Linington, R.G.1
  • 55
    • 0034092263 scopus 로고    scopus 로고
    • Isolation, structure determination, and biological activity of lyngbya- bellin a from the marine cyanobacterium lyngbya majuscula
    • Luesch H et al (2000) Isolation, structure determination, and biological activity of Lyngbya- bellin A from the marine cyanobacterium Lyngbya majuscula. J Nat Prod 63 (5):611-615
    • (2000) J Nat Prod , vol.63 , Issue.5 , pp. 611-615
    • Luesch, H.1
  • 56
    • 0034898713 scopus 로고    scopus 로고
    • Isolation of dolastatin 10 from the marine cyanobacterium symploca species vp642 and total stereochemistry and biological evaluation of its analogue symplo- statin 1
    • Luesch H et al (2001) Isolation of dolastatin 10 from the marine cyanobacterium Symploca species VP642 and total stereochemistry and biological evaluation of its analogue symplo- statin 1. J Nat Prod 64 (7):907-910
    • (2001) J Nat Prod , vol.64 , Issue.7 , pp. 907-910
    • Luesch, H.1
  • 57
    • 0035093655 scopus 로고    scopus 로고
    • Pitipeptolides a and b, new cyclodepsipeptides from the marine cyanobacterium lyngbya majuscula
    • Luesch H et al (2001) Pitipeptolides A and B, new cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. J Nat Prod 64 (3):304-307
    • (2001) J Nat Prod , vol.64 , Issue.3 , pp. 304-307
    • Luesch, H.1
  • 58
    • 0034833620 scopus 로고    scopus 로고
    • Total structure determination of apratoxin a, a potent novel cytotoxin from the marine cyanobacterium lyngbya majuscula
    • Luesch H et al (2001) Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula. J Am Chem Soc 123 (23):5418-5423
    • (2001) J am Chem Soc , vol.123 , Issue.23 , pp. 5418-5423
    • Luesch, H.1
  • 59
    • 0036929670 scopus 로고    scopus 로고
    • Lyngbyaloside b, a new glycoside macrolide from a palauan marine cyanobacterium, lyngbya sp
    • Luesch H et al (2002) Lyngbyaloside B, a new glycoside macrolide from a Palauan marine cyanobacterium, Lyngbya sp. J Nat Prod 65 (12):1945-1948
    • (2002) J Nat Prod , vol.65 , Issue.12 , pp. 1945-1948
    • Luesch, H.1
  • 60
    • 0036009896 scopus 로고    scopus 로고
    • New apratoxins of marine cyanobacterial origin from guam and palau
    • Luesch H et al (2002) New apratoxins of marine cyanobacterial origin from Guam and Palau. Bioorg Med Chem 10 (6):1973-1978
    • (2002) Bioorg Med Chem , vol.10 , Issue.6 , pp. 1973-1978
    • Luesch, H.1
  • 61
    • 0036165655 scopus 로고    scopus 로고
    • Symplostatin 3, a new dolastatin 10 analogue from the marine cyanobacterium symploca sp. Vp452
    • Luesch H et al (2002) Symplostatin 3, a new dolastatin 10 analogue from the marine cyanobacterium Symploca sp. Vp452. J Nat Prod 65 (1):16-20
    • (2002) J Nat Prod , vol.65 , Issue.1 , pp. 16-20
    • Luesch, H.1
  • 62
    • 33750012824 scopus 로고    scopus 로고
    • Total synthesis of the cyclodepsipeptide apratoxin a and its analogues and assessment of their biological activities
    • Ma D et al (2006) Total synthesis of the cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activities. Chemistry 12 (29):7615-7626
    • (2006) Chemistry , vol.12 , Issue.29 , pp. 7615-7626
    • Ma, D.1
  • 63
    • 0037007739 scopus 로고    scopus 로고
    • Caylobolide a, a unique 36-membered macrolactone from a bahamian lyngbya majuscula
    • MacMillan JB, Molinski TF (2002) Caylobolide A, a unique 36-membered macrolactone from a Bahamian Lyngbya majuscula. Org Lett 4 (9):1535-1538
    • (2002) Org Lett , vol.4 , Issue.9 , pp. 1535-1538
    • MacMillan, J.B.1    Molinski, T.F.2
  • 64
    • 79951532784 scopus 로고    scopus 로고
    • Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a papua new guinea marine cyanobacterium
    • Malloy KL et al (2011) Malyngamide 2, an oxidized lipopeptide with nitric oxide inhibiting activity from a Papua new guinea marine cyanobacterium. J Nat Prod 74 (1):95-98
    • (2011) J Nat Prod , vol.74 , Issue.1 , pp. 95-98
    • Malloy, K.L.1
  • 65
    • 0036306443 scopus 로고    scopus 로고
    • Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly
    • Marquez BL et al (2002) Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly. J Nat Prod 65 (6):866-871
    • (2002) J Nat Prod , vol.65 , Issue.6 , pp. 866-871
    • Marquez, B.L.1
  • 66
    • 42149175604 scopus 로고    scopus 로고
    • Antimicrobial and cytotoxic assessment of marine cyanobacteria- synechocystis and synechococcus
    • Martins RF et al (2008) Antimicrobial and cytotoxic assessment of marine cyanobacteria- Synechocystis and Synechococcus. Mar Drugs 6 (1):1-11
    • (2008) Mar Drugs , vol.6 , Issue.1 , pp. 1-11
    • Martins, R.F.1
  • 67
    • 84944599697 scopus 로고    scopus 로고
    • Cytotoxicity of picocyanobacteria strains of the genera cyanobium on osteosarcoma cells. In: European calcified tissue society conference ects 2013
    • Martins R et al (2013) Cytotoxicity of picocyanobacteria strains of the genera Cyanobium on osteosarcoma cells. In: European calcified tissue society conference ECTS 2013. Lisbon (Portugal)
    • (2013) Lisbon (Portugal)
    • Martins, R.1
  • 68
    • 33847063427 scopus 로고    scopus 로고
    • Lyngbyastatin 4, a dolastatin 13
    • Matthew S et al (2007) Lyngbyastatin 4, a dolastatin 13 analogue with elastase and chymotrypsin inhibitory activity from the marine cyanobacterium Lyngbya confervoides. J Nat Prod 70 (1):124-127
    • (2007) J Nat Prod , vol.70 , Issue.1 , pp. 124-127
    • Matthew, S.1
  • 69
    • 47549102471 scopus 로고    scopus 로고
    • Apratoxin e, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium lyngbya bouillonii
    • Matthew S, Schupp PJ, Luesch H (2008) Apratoxin E, a cytotoxic peptolide from a guamanian collection of the marine cyanobacterium Lyngbya bouillonii. J Nat Prod 71 (6):1113-1116
    • (2008) J Nat Prod , vol.71 , Issue.6 , pp. 1113-1116
    • Matthew, S.1    Schupp, P.J.2    Luesch, H.3
  • 70
    • 40849117988 scopus 로고    scopus 로고
    • Pompanopeptins a and b, new cyclic peptides from the marine cyanobacterium lyngbya confervoides
    • Matthew S et al (2008) Pompanopeptins A and B, new cyclic peptides from the marine cyanobacterium Lyngbya confervoides. Tetrahedron 64 (18):4081-4089
    • (2008) Tetrahedron , vol.64 , Issue.18 , pp. 4081-4089
    • Matthew, S.1
  • 71
    • 65949106959 scopus 로고    scopus 로고
    • Largamides a-c, tiglic acid-containing cyclodepsi- peptides with elastase-inhibitory activity from the marine cyanobacterium lyngbya confer- voides
    • Matthew S, Paul VJ, Luesch H (2009) Largamides A-C, tiglic acid-containing cyclodepsi- peptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confer- voides.Planta Med 75 (5):528-533
    • (2009) Planta Med , vol.75 , Issue.5 , pp. 528-533
    • Matthew, S.1    Paul, V.J.2    Luesch, H.3
  • 72
    • 70549111144 scopus 로고    scopus 로고
    • Tiglicamides a-c, cyclodepsipeptides from the marine cyanobacterium lyngbya confervoides
    • Matthew S, Paul VJ, Luesch H (2009) Tiglicamides A-C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides. Phytochemistry 70 (17-18):2058-2063
    • (2009) Phytochemistry , vol.70 , Issue.17-18 , pp. 2058-2063
    • Matthew, S.1    Paul, V.J.2    Luesch, H.3
  • 73
    • 77957242141 scopus 로고    scopus 로고
    • Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium lyngbya bouillonii from guam
    • Matthew S et al (2010) Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam. J Nat Prod 73 (9):1544-1552
    • (2010) J Nat Prod , vol.73 , Issue.9 , pp. 1544-1552
    • Matthew, S.1
  • 74
    • 44049107679 scopus 로고    scopus 로고
    • Coibamide a, a potent antiproliferative cyclic depsipeptide from the panamanian marine cyanobacterium leptolyngbya sp
    • Medina RA et al (2008) Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp. J Am Chem Soc 130 (20):6324-6325
    • (2008) J am Chem Soc , vol.130 , Issue.20 , pp. 6324-6325
    • Medina, R.A.1
  • 75
    • 79957799952 scopus 로고    scopus 로고
    • Cytotoxic veraguamides, alkynyl bromide-containing cyclic dep- sipeptides from the marine cyanobacterium cf
    • Mevers E et al (2011) Cytotoxic veraguamides, alkynyl bromide-containing cyclic dep- sipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera. J Nat Prod 74 (5):928-936
    • (2011) J Nat Prod , vol.74 , Issue.5 , pp. 928-936
    • Mevers, E.1
  • 76
    • 58149189779 scopus 로고    scopus 로고
    • Drug development from marine natural products
    • Molinski TF et al (2009) Drug development from marine natural products. Nat Rev Drug Discov 8 (1):69-85
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.1 , pp. 69-85
    • Molinski, T.F.1
  • 77
    • 80052945621 scopus 로고    scopus 로고
    • Pitipeptolides c-f, antimycobacterial cyclodepsip- eptides from the marine cyanobacterium lyngbya majuscula from guam
    • Montaser R, Paul VJ, Luesch H (2011) Pitipeptolides C-F, antimycobacterial cyclodepsip- eptides from the marine cyanobacterium Lyngbya majuscula from Guam. Phytochemistry 72 (16):2068-2074
    • (2011) Phytochemistry , vol.72 , Issue.16 , pp. 2068-2074
    • Montaser, R.1    Paul, V.J.2    Luesch, H.3
  • 78
    • 79951525515 scopus 로고    scopus 로고
    • Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium lyngbya majuscula from guam
    • Montaser R et al (2011) Pitiprolamide, a proline-rich dolastatin 16 analogue from the marine cyanobacterium Lyngbya majuscula from Guam. J Nat Prod 74 (1):109-112
    • (2011) J Nat Prod , vol.74 , Issue.1 , pp. 109-112
    • Montaser, R.1
  • 79
    • 0030670103 scopus 로고    scopus 로고
    • Induction of apoptosis by cryptophycin 1, a new antimicrotubule agent
    • Mooberry SL, Busquets L, Tien G (1997) Induction of apoptosis by cryptophycin 1, a new antimicrotubule agent. Int J Cancer 73 (3):440-448
    • (1997) Int J Cancer , vol.73 , Issue.3 , pp. 440-448
    • Mooberry, S.L.1    Busquets, L.2    Tien, G.3
  • 80
    • 0037457479 scopus 로고    scopus 로고
    • The molecular pharmacology of symplostatin 1: A new antimitotic dolastatin 10 analog
    • Mooberry SL et al (2003) The molecular pharmacology of symplostatin 1: a new antimitotic dolastatin 10 analog. Int J Cancer 104 (4):512-521
    • (2003) Intj Cancer , vol.104 , Issue.4 , pp. 512-521
    • Mooberry, S.L.1
  • 82
    • 0034909167 scopus 로고    scopus 로고
    • Antillatoxin b, a neurotoxic lipopeptide from the marine cyanobacterium lyngbya majuscula
    • Nogle LM, Okino T, Gerwick WH (2001) Antillatoxin B, a neurotoxic lipopeptide from the marine cyanobacterium Lyngbya majuscula. J Nat Prod 64 (7):983-985
    • (2001) J Nat Prod , vol.64 , Issue.7 , pp. 983-985
    • Nogle, L.M.1    Okino, T.2    Gerwick, W.H.3
  • 83
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74 (4):609-619
    • (1993) Cell , vol.74 , Issue.4 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 84
    • 0009979308 scopus 로고    scopus 로고
    • Marine plankton
    • Potts M (eds) The ecology of cyanobacteria. Springer, Netherlands
    • Paerl HW (2002) Marine plankton. In: Whitton BA, Potts M (eds) The ecology of cyanobacteria. Springer, Netherlands, pp 121-148
    • (2002) Whitton BA , pp. 121-148
    • Paerl, H.W.1
  • 85
    • 84859602331 scopus 로고    scopus 로고
    • The carmaphycins: New proteasome inhibitors exhibiting an alpha, beta-epoxyketone warhead from a marine cyanobacterium
    • Pereira AR et al (2012) The Carmaphycins: new proteasome inhibitors exhibiting an alpha, beta-epoxyketone warhead from a marine cyanobacterium. Chembiochem 13 (6):810-817
    • (2012) Chembiochem , vol.13 , Issue.6 , pp. 810-817
    • Pereira, A.R.1
  • 86
    • 42249086977 scopus 로고    scopus 로고
    • Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms (1a)
    • Pettit GR et al (2008) Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms (1a). J Nat Prod 71 (3):438-444
    • (2008) J Nat Prod , vol.71 , Issue.3 , pp. 438-444
    • Pettit, G.R.1
  • 87
    • 0033002547 scopus 로고    scopus 로고
    • Phase i trial of dolastatin-10 (Nsc 376128) in patients with advanced solid tumors
    • Pitot HC et al (1999) Phase I trial of dolastatin-10 (NSC 376128) in patients with advanced solid tumors. Clin Cancer Res 5 (3):525-531
    • (1999) Clin Cancer Res , vol.5 , Issue.3 , pp. 525-531
    • Pitot, H.C.1
  • 88
    • 33750446641 scopus 로고    scopus 로고
    • Largamides a-h, unusual cyclic peptides from the marine cyanobacterium oscillatoria sp
    • Plaza A, Bewley CA (2006) Largamides A-H, unusual cyclic peptides from the marine cyanobacterium Oscillatoria sp. J Org Chem 71 (18):6898-6907
    • (2006) J Org Chem , vol.71 , Issue.18 , pp. 6898-6907
    • Plaza, A.1    Bewley, C.A.2
  • 89
    • 69249100500 scopus 로고    scopus 로고
    • Human caspases: Activation, specificity, and regulation
    • Pop C, Salvesen GS (2009) Human caspases: activation, specificity, and regulation. J Biol Chem 284 (33):21777-21781
    • (2009) J Biol Chem , vol.284 , Issue.33 , pp. 21777-21781
    • Pop, C.1    Salvesen, G.S.2
  • 90
    • 78649335125 scopus 로고    scopus 로고
    • Depsipeptides from a guamanian marine cyanobacterium, lyngbya bouillonii, with selective inhibition of serine proteases
    • Rubio BK et al (2010) Depsipeptides from a Guamanian marine cyanobacterium, Lyngbya bouillonii, with selective inhibition of serine proteases. Tetrahedron Lett 51 (51):6718-6721
    • (2010) Tetrahedron Lett , vol.51 , Issue.51 , pp. 6718-6721
    • Rubio, B.K.1
  • 91
    • 77957224565 scopus 로고    scopus 로고
    • Caylobolide b, a macrolactone from symplo- statin 1-producing marine cyanobacteria phormidium spp. From florida
    • Salvador LA, Paul VJ, Luesch H (2010) Caylobolide B, a macrolactone from symplo- statin 1-producing marine cyanobacteria Phormidium spp. From Florida. J Nat Prod 73 (9):1606-1609
    • (2010) J Nat Prod , vol.73 , Issue.9 , pp. 1606-1609
    • Salvador, L.A.1    Paul, V.J.2    Luesch, H.3
  • 92
    • 79957810219 scopus 로고    scopus 로고
    • Veraguamides a-g
    • Salvador LA et al (2011) Veraguamides A-G, cyclic hexadepsipeptides from a dolastatin 16-producing cyanobacterium Symploca cf. Hydnoides from Guam. J Nat Prod 74(5):917- 927
    • (2011) J Nat Prod , pp. 927
    • Salvador, L.A.1
  • 93
    • 0000642932 scopus 로고    scopus 로고
    • The fossil record: Tracing the roots of the cyanobacterial lineage
    • Whitton BA, Potts M, Dordrecht, Kluwer Academic Publishers
    • Schopf WJ (2000) The fossil record: tracing the roots of the cyanobacterial lineage. In: Whitton BA, Potts M (eds) The ecology of cyanobacteria. Their diversity in time and space. Dordrecht, Kluwer Academic Publishers
    • (2000) The Ecology of Cyanobacteria. Their Diversity in Time and Space
    • Schopf, W.J.1
  • 94
    • 24044549646 scopus 로고    scopus 로고
    • Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the portuguese coast
    • Selheim F et al (2005) Neuro-apoptogenic and blood platelet targeting toxins in benthic marine cyanobacteria from the Portuguese coast. Aquat Toxicol 74 (4):294-306
    • (2005) Aquat Toxicol , vol.74 , Issue.4 , pp. 294-306
    • Selheim, F.1
  • 95
    • 84876928215 scopus 로고    scopus 로고
    • Malyngamide 4, a new lipopeptide from the red sea marine cyanobacterium moorea producens (Formerly lyngbya majuscula)
    • Shaala LA et al (2013) Malyngamide 4, a new lipopeptide from the Red sea marine cyanobacterium Moorea producens (formerly Lyngbya majuscula). Phytochem Lett 6(2):183- 188
    • (2013) Phytochem Lett , pp. 188
    • Shaala, L.A.1
  • 96
    • 3343011970 scopus 로고    scopus 로고
    • Caspase activation, inhibition, and reactivation: A mechanistic view
    • Shi YG (2004) Caspase activation, inhibition, and reactivation: a mechanistic view. Protein Sci 13 (8):1979-1987
    • (2004) Protein Sci , vol.13 , Issue.8 , pp. 1979-1987
    • Shi, Y.G.1
  • 97
    • 33646023394 scopus 로고    scopus 로고
    • Belamide a, a new antimitotic tetrapeptide from a panamanian marine cyanobacterium
    • Simmons TL et al (2006) Belamide A, a new antimitotic tetrapeptide from a Panamanian marine cyanobacterium. Tetrahedron Lett 47 (20):3387-3390
    • (2006) Tetrahedron Lett , vol.47 , Issue.20 , pp. 3387-3390
    • Simmons, T.L.1
  • 98
    • 79959767039 scopus 로고    scopus 로고
    • Cyanobacteria: An emerging source for drug discovery
    • Singh RK et al (2011) Cyanobacteria: an emerging source for drug discovery. J Antibiot (Tokyo) 64(6):401-412
    • (2011) J Antibiot (Tokyo) , vol.64 , Issue.6 , pp. 401-412
    • Singh, R.K.1
  • 99
    • 69749085714 scopus 로고    scopus 로고
    • Inhibition of human leukocyte elastase by brunsvicamides a-c: Cyanobacterial cyclic peptides
    • Sisay MT et al (2009) Inhibition of human leukocyte elastase by brunsvicamides a-C: cyanobacterial cyclic peptides. Chemmedchem 4 (9):1425-1429
    • (2009) Chemmedchem , vol.4 , Issue.9 , pp. 1425-1429
    • Sisay, M.T.1
  • 100
    • 0035831473 scopus 로고    scopus 로고
    • Executioner caspase-3, -6, and -7 perform distinct, nonredundant roles during the demolition phase of apoptosis
    • Slee EA, Adrain C, Martin SJ (2001) Executioner caspase-3, -6, and -7 perform distinct, nonredundant roles during the demolition phase of apoptosis. J Biol Chem 276 (10):7320-7326
    • (2001) J Biol Chem , vol.276 , Issue.10 , pp. 7320-7326
    • Slee, E.A.1    Adrain, C.2    Martin, S.J.3
  • 101
    • 33744457678 scopus 로고    scopus 로고
    • Trypsin in colorectal cancer: Molecular biological mechanisms of proliferation, invasion, and metastasis
    • Soreide K, Janssen EA, Korner H, Baak JP (2006) Trypsin in colorectal cancer: molecular biological mechanisms of proliferation, invasion, and metastasis. J Pathol 209 (2): 147-156
    • (2006) J Pathol , vol.209 , Issue.2 , pp. 147-156
    • Soreide, K.1    Janssen, E.A.2    Korner, H.3    Baak, J.P.4
  • 102
    • 72049131567 scopus 로고    scopus 로고
    • Effects od elastase inhibitor on the epithelial cell apoptosis in bleomycin pulmonary fibrosis
    • Song JS, Kang CH, Rhee CK, Yoon HK, Kim YK, Moon HS, Park SH (2009) Effects od elastase inhibitor on the epithelial cell apoptosis in bleomycin pulmonary fibrosis. Exp Lung Res 35 (10): 817-829
    • (2009) Exp Lung Res , vol.35 , Issue.10 , pp. 817-829
    • Song, J.S.1    Kang, C.H.2    Rhee, C.K.3    Yoon, H.K.4    Kim, Y.K.5    Moon, H.S.6    Park, S.H.7
  • 103
    • 70349934410 scopus 로고    scopus 로고
    • Alotamide a, a novel neuropharmacological agent from the marine cyanobacterium lyngbya bouillonii
    • Soria-Mercado IE et al (2009) Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii. Org Lett 11 (20):4704-4707
    • (2009) Org Lett , vol.11 , Issue.20 , pp. 4704-4707
    • Soria-Mercado, I.E.1
  • 105
    • 77950416522 scopus 로고    scopus 로고
    • Palmyramide a, a cyclic depsipeptide from a palmyra atoll collection of the marine cyanobacterium lyngbya majuscula
    • Taniguchi M et al (2010) Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula. J Nat Prod 73 (3):393-398
    • (2010) J Nat Prod , vol.73 , Issue.3 , pp. 393-398
    • Taniguchi, M.1
  • 106
    • 36348972843 scopus 로고    scopus 로고
    • Lyngbyastatins 5-7, potent elastase inhibitors from floridian marine cyanobacteria, lyngbya spp
    • Taori K et al (2007) Lyngbyastatins 5-7, potent elastase inhibitors from Floridian marine cyanobacteria, Lyngbya spp. J Nat Prod 70 (10):1593-1600
    • (2007) J Nat Prod , vol.70 , Issue.10 , pp. 1593-1600
    • Taori, K.1
  • 107
    • 54149108953 scopus 로고    scopus 로고
    • Kempopeptins a and b, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, lyngbya sp
    • Taori K, Paul VJ, Luesch H (2008) Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp. J Nat Prod 71 (9):1625-1629
    • (2008) J Nat Prod , vol.71 , Issue.9 , pp. 1625-1629
    • Taori, K.1    Paul, V.J.2    Luesch, H.3
  • 108
    • 39049135494 scopus 로고    scopus 로고
    • Structure and activity of largazole, a potent antiproliferative agent from the floridian marine cyanobacterium symploca sp
    • Taori K, Paul VJ, Luesch H (2008) Structure and activity of largazole, a potent antiproliferative agent from the Floridian marine cyanobacterium Symploca sp. J Am Chem Soc 130 (6):1806-1807
    • (2008) J am Chem Soc , vol.130 , Issue.6 , pp. 1806-1807
    • Taori, K.1    Paul, V.J.2    Luesch, H.3
  • 109
    • 70350637641 scopus 로고    scopus 로고
    • Bisebromoamide, a potent cytotoxic peptide from the marine cyanobacterium lyngbya sp.: Isolation, stereostructure, and biological activity
    • Teruya T et al (2009) Bisebromoamide, a potent cytotoxic peptide from the marine cyanobacterium Lyngbya sp.: isolation, stereostructure, and biological activity. Org Lett 11 (21):5062-5065
    • (2009) Org Lett , vol.11 , Issue.21 , pp. 5062-5065
    • Teruya, T.1
  • 110
    • 66149169967 scopus 로고    scopus 로고
    • Biselyngbyaside, a macrolide glycoside from the marine cyanobacterium lyngbya sp
    • Teruya T et al (2009) Biselyngbyaside, a macrolide glycoside from the marine cyanobacterium Lyngbya sp. Org Lett 11 (11):2421-2424
    • (2009) Org Lett , vol.11 , Issue.11 , pp. 2421-2424
    • Teruya, T.1
  • 111
    • 84885045241 scopus 로고    scopus 로고
    • Apratoxin h and apratoxin a sulfoxide from the red sea cyanobacterium moorea producens
    • Thornburg CC et al (2013) Apratoxin H and apratoxin A sulfoxide from the Red sea cyanobacterium Moorea producens. J Nat Prod 76 (9):1781-1788
    • (2013) J Nat Prod , vol.76 , Issue.9 , pp. 1781-1788
    • Thornburg, C.C.1
  • 112
    • 77954373563 scopus 로고    scopus 로고
    • Evolved diversification of a modular natural product pathway: Apratoxins f and g, two cytotoxic cyclic depsipeptides from a palmyra collection of lyngbya bouillonii
    • Tidgewell K et al (2010) Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii. Chembiochem 11 (10):1458-1466
    • (2010) Chembiochem , vol.11 , Issue.10 , pp. 1458-1466
    • Tidgewell, K.1
  • 113
    • 80054925331 scopus 로고    scopus 로고
    • Lagunamide c, a cytotoxic cyclodepsipeptide from the marine cyanobacterium lyngbya majuscula
    • Tripathi A et al (2011) Lagunamide C, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Lyngbya majuscula. Phytochemistry 72:2369-2375
    • (2011) Phytochemistry , vol.72 , pp. 2369-2375
    • Tripathi, A.1
  • 114
    • 84862899581 scopus 로고    scopus 로고
    • Biochemical studies of the lagunamides, potent cytotoxic cyclic depsipeptides from the marine cyanobacterium lyngbya majuscula
    • Tripathi A et al (2012) Biochemical studies of the lagunamides, potent cytotoxic cyclic depsipeptides from the marine cyanobacterium Lyngbya majuscula. Mar Drugs 10(5):1126—1137
    • (2012) Mar Drugs 10(5)
    • Tripathi, A.1
  • 115
    • 33748308883 scopus 로고    scopus 로고
    • Targeting proteases: Successes, failures and future prospects
    • Turk B (2006) Targeting proteases: successes, failures and future prospects. Nature Rev 5 (9):785-799
    • (2006) Nature Rev , vol.5 , Issue.9 , pp. 785-799
    • Turk, B.1
  • 116
    • 0031960723 scopus 로고    scopus 로고
    • Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc
    • Turner T et al (1998) Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc. Prostate 34 (3):175-181
    • (1998) Prostate , vol.34 , Issue.3 , pp. 175-181
    • Turner, T.1
  • 117
    • 0032877433 scopus 로고    scopus 로고
    • Bax:Bcl-2 ratio modulation by bryostatin 1 and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-b acute lymphoblastic leukemia cell line, reh
    • Wall NR, Mohammad RM, Al-Katib AM (1999) Bax:Bcl-2 ratio modulation by bryostatin 1 and novel antitubulin agents is important for susceptibility to drug induced apoptosis in the human early pre-B acute lymphoblastic leukemia cell line, Reh. Leuk Res 23 (10):881-888
    • (1999) Leuk Res , vol.23 , Issue.10 , pp. 881-888
    • Wall, N.R.1    Mohammad, R.M.2    Al-Katib, A.M.3
  • 118
    • 3843145001 scopus 로고    scopus 로고
    • Total synthesis and biological evaluation of + -kalkitoxin, a cytotoxic metabolite of the cyanobacterium lyngbya majuscula
    • White JD et al (2004) Total synthesis and biological evaluation of + -kalkitoxin, a cytotoxic metabolite of the cyanobacterium Lyngbya majuscula. Org Biomol Chem 2 (14):2092-2102
    • (2004) Org Biomol Chem , vol.2 , Issue.14 , pp. 2092-2102
    • White, J.D.1
  • 119
    • 14644425290 scopus 로고    scopus 로고
    • Ecotoxicological effects of selected cyanobacterial secondary metabolites a short review
    • Wiegand C, Pflugmacher S (2005) Ecotoxicological effects of selected cyanobacterial secondary metabolites a short review. Toxicol Appl Pharmacol 203 (3):201-218
    • (2005) Toxicol Appl Pharmacol , vol.203 , Issue.3 , pp. 201-218
    • Wiegand, G.1    Pflugmacher, C.S.2
  • 120
    • 0036158494 scopus 로고    scopus 로고
    • Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium lyngbya confervoides
    • Williams PG et al (2002) Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides. J Nat Prod 65 (1):29-31
    • (2002) J Nat Prod , vol.65 , Issue.1 , pp. 29-31
    • Williams, P.G.1
  • 121
    • 0036741258 scopus 로고    scopus 로고
    • Tasiamide, a cytotoxic peptide from the marine cyanobacterium symploca sp
    • Williams PG et al (2002) Tasiamide, a cytotoxic peptide from the marine cyanobacterium Symploca sp. J Nat Prod 65 (9):1336-1339
    • (2002) J Nat Prod , vol.65 , Issue.9 , pp. 1336-1339
    • Williams, P.G.1
  • 122
    • 0037513401 scopus 로고    scopus 로고
    • Tasipeptins a and b: New cytotoxic depsipeptides from the marine cyanobacterium symploca sp
    • Williams PG et al (2003) Tasipeptins A and B: new cytotoxic depsipeptides from the marine cyanobacterium Symploca sp. J Nat Prod 66 (5):620-624
    • (2003) J Nat Prod , vol.66 , Issue.5 , pp. 620-624
    • Williams, P.G.1
  • 123
    • 0042844745 scopus 로고    scopus 로고
    • The isolation and structure elucidation of tasiamide b, a 4-amino- 3-hydroxy-5-phenylpentanoic acid containing peptide from the marine cyanobacterium symploca sp
    • Williams PG et al (2003) The isolation and structure elucidation of Tasiamide B, a 4-amino- 3-hydroxy-5-phenylpentanoic acid containing peptide from the marine Cyanobacterium Symploca sp. J Nat Prod 66 (7):1006-1009
    • (2003) J Nat Prod , vol.66 , Issue.7 , pp. 1006-1009
    • Williams, P.G.1
  • 124
    • 0346396114 scopus 로고    scopus 로고
    • The structure of palau’amide, a potent cytotoxin from a species of the marine cyanobacterium lyngbya
    • Williams PG et al (2003) The structure of Palau’amide, a potent cytotoxin from a species of the marine cyanobacterium Lyngbya. J Nat Prod 66 (12):1545-1549
    • (2003) J Nat Prod , vol.66 , Issue.12 , pp. 1545-1549
    • Williams, P.G.1
  • 125
    • 0038188663 scopus 로고    scopus 로고
    • Ulongapeptin, a cytotoxic cyclic depsipeptide from a palauan marine cyanobacterium lyngbya sp
    • Williams PG et al (2003) Ulongapeptin, a cytotoxic cyclic depsipeptide from a Palauan marine cyanobacterium Lyngbya sp. J Nat Prod 66 (5):651-654
    • (2003) J Nat Prod , vol.66 , Issue.5 , pp. 651-654
    • Williams, P.G.1
  • 126
    • 80053348989 scopus 로고    scopus 로고
    • Apoptosis in cancer: From pathogenesis to treatment
    • Wong RS (2011) Apoptosis in cancer: from pathogenesis to treatment. J Exp Clin Cancer Res 30:87
    • (2011) J Exp Clin Cancer Res , vol.30 , pp. 87
    • Wong, R.S.1
  • 127
    • 40649123558 scopus 로고    scopus 로고
    • The marine lipopeptide somocystinamide a triggers apoptosis via caspase 8
    • Wrasidlo W et al (2008) The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc Natl Acad Sci U S A 105 (7):2313-2318
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.7 , pp. 2313-2318
    • Wrasidlo, W.1
  • 128
    • 84855551980 scopus 로고    scopus 로고
    • Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts
    • Yonezawa T et al (2012) Biselyngbyaside, isolated from marine cyanobacteria, inhibits osteoclastogenesis and induces apoptosis in mature osteoclasts. J Cell Biochem 113 (2):440-448
    • (2012) J Cell Biochem , vol.113 , Issue.2 , pp. 440-448
    • Yonezawa, T.1
  • 129
    • 77949831890 scopus 로고    scopus 로고
    • Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells
    • Zeng X et al (2010) Total synthesis and biological evaluation of largazole and derivatives with promising selectivity for cancers cells. Org Lett 12 (6):1368-1371
    • (2010) Org Lett , vol.12 , Issue.6 , pp. 1368-1371
    • Zeng, X.1
  • 130
    • 25444480016 scopus 로고    scopus 로고
    • Total synthesis and cytotoxicity studies of a cyclic depsipeptide with proposed structure of palau’amide
    • Zou B, Long K, Ma DW (2005) Total synthesis and cytotoxicity studies of a cyclic depsipeptide with proposed structure of palau’amide. Org Lett 7 (19):4237-4240
    • (2005) Org Lett , vol.7 , Issue.19 , pp. 4237-4240
    • Zou, B.1    Long, K.2    Ma, D.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.