-
1
-
-
33947104489
-
Bioactive natural products from marine cyanobacteria for drug discovery
-
DOI 10.1016/j.phytochem.2007.01.012, PII S0031942207000519
-
Tan, L.T. Bioactive natural products from marine cyanobacteria for drug discovery. Phytochemistry 2007, 68, 954-979. (Pubitemid 46413338)
-
(2007)
Phytochemistry
, vol.68
, Issue.7
, pp. 954-979
-
-
Tan, L.T.1
-
2
-
-
0032475992
-
Harnessing the biosynthetic code: Combinations, permutations, and mutations
-
DOI 10.1126/science.282.5386.63
-
Cane, D.E.; Walsh, C.T.; Khosla, C. Harnessing the biosynthetic code: Combinations, permutations, and mutations. Science 1998, 282, 63-68. (Pubitemid 28471127)
-
(1998)
Science
, vol.282
, Issue.5386
, pp. 63-68
-
-
Cane, D.E.1
Walsh, C.T.2
Khosla, C.3
-
3
-
-
78650214297
-
Filamentous tropical marine cyanobacteria: A rich source of natural products for anticancer drug discovery
-
Tan, L.T. Filamentous tropical marine cyanobacteria: A rich source of natural products for anticancer drug discovery. J. Appl. Phycol. 2010, 22, 659-676.
-
(2010)
J. Appl. Phycol.
, vol.22
, pp. 659-676
-
-
Tan, L.T.1
-
4
-
-
84858032909
-
Brentuximab vedotin: A new age in the treatment of Hodgkin lymphoma and anaplastic large cell lymphoma
-
Minich, S.S. Brentuximab vedotin: A new age in the treatment of Hodgkin lymphoma and anaplastic large cell lymphoma. Ann. Pharmacother. 2012, 46, 377-383.
-
(2012)
Ann. Pharmacother.
, vol.46
, pp. 377-383
-
-
Minich, S.S.1
-
5
-
-
84856406381
-
Lessons from the past and charting the future of marine natural products drug discovery and chemical biology
-
Gerwick, W.H.; Moore, B.S. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. Chem. Biol. 2012, 19, 85-98.
-
(2012)
Chem. Biol.
, vol.19
, pp. 85-98
-
-
Gerwick, W.H.1
Moore, B.S.2
-
6
-
-
45649084241
-
Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula
-
Tan, L.T.; Chang, Y.Y.; Tripathi, A. Besarhanamides A and B from the marine cyanobacterium Lyngbya majuscula. Phytochemistry 2008, 69, 2067-2069.
-
(2008)
Phytochemistry
, vol.69
, pp. 2067-2069
-
-
Tan, L.T.1
Chang, Y.Y.2
Tripathi, A.3
-
7
-
-
60549092554
-
Hantupeptin A, a cytotoxic cyclic depsipeptide from a Singapore collection of Lyngbya majuscula
-
Tripathi, A.; Puddick, J.; Prinsep, M.R.; Lee, P.P.; Tan, L.T. Hantupeptin A, a cytotoxic cyclic depsipeptide from a Singapore collection of Lyngbya majuscula. J. Nat. Prod. 2009, 72, 29-32.
-
(2009)
J. Nat. Prod.
, vol.72
, pp. 29-32
-
-
Tripathi, A.1
Puddick, J.2
Prinsep, M.R.3
Lee, P.P.4
Tan, L.T.5
-
8
-
-
73649113803
-
Hantupeptins B and C, cytotoxic cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula
-
Tripathi, A.; Puddick, J.; Prinsep, M.R.; Lee, P.P.; Tan, L.T. Hantupeptins B and C, cytotoxic cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. Phytochemistry 2010, 71, 307-311.
-
(2010)
Phytochemistry
, vol.71
, pp. 307-311
-
-
Tripathi, A.1
Puddick, J.2
Prinsep, M.R.3
Lee, P.P.4
Tan, L.T.5
-
9
-
-
78650205958
-
Lagunamides A and B: Cytotoxic and antimalarial cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula
-
Tripathi, A.; Puddick, J.; Prinsep, M.R.; Rottmann, M.; Tan, L.T. Lagunamides A and B: cytotoxic and antimalarial cyclodepsipeptides from the marine cyanobacterium Lyngbya majuscula. J. Nat. Prod. 2010, 73, 1810-1814.
-
(2010)
J. Nat. Prod.
, vol.73
, pp. 1810-1814
-
-
Tripathi, A.1
Puddick, J.2
Prinsep, M.R.3
Rottmann, M.4
Tan, L.T.5
-
10
-
-
0012285509
-
Natural products as inducers of apoptosis: Implication for cancer therapy and prevention
-
Taraphdar, A.K.; Roy, M.; Bhattacharya, R.K. Natural products as inducers of apoptosis: Implication for cancer therapy and prevention. Curr. Sci. 2001, 80, 1387-1396. (Pubitemid 33620231)
-
(2001)
Current Science
, vol.80
, Issue.11
, pp. 1387-1396
-
-
Taraphdar, A.K.1
Roy, M.2
Bhattacharya, R.K.3
-
12
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell 2000, 100, 57-70. (Pubitemid 30046295)
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
4344694626
-
Kulokekahilide-2, a cytotoxic depsipeptide from a cephalaspidean mollusk Philinopsis Speciosa
-
DOI 10.1021/np049949f
-
Nakao, Y.; Yoshida, W.Y.; Takada, Y.; Kimura, J.; Yang, L.; Mooberry, S.L.; Scheuer, P.J. Kulokekahilide-2, a cytotoxic depsipeptide from a cephalaspidean mollusk Philinopsis speciosa. J. Nat. Prod. 2004, 67, 1332-1340. (Pubitemid 39145639)
-
(2004)
Journal of Natural Products
, vol.67
, Issue.8
, pp. 1332-1340
-
-
Nakao, Y.1
Yoshida, W.Y.2
Takada, Y.3
Kimura, J.4
Yang, L.5
Mooberry, S.L.6
Scheuer, P.J.7
-
14
-
-
33744460793
-
Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula
-
DOI 10.1021/np0503911
-
Han, B.; Gross, H.; Goeger, D.E.; Mooberry, S.L.; Gerwick, W.H. Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula. J. Nat. Prod. 2006, 69, 572-575. (Pubitemid 43798104)
-
(2006)
Journal of Natural Products
, vol.69
, Issue.4
, pp. 572-575
-
-
Han, B.1
Gross, H.2
Goeger, D.E.3
Mooberry, S.L.4
Gerwick, W.H.5
-
15
-
-
38349141838
-
Revised absolute stereochemistry of natural kulokekahilide-2
-
Takada, Y.; Umehara, M.; Nakao, Y.; Kimura, J. Revised absolute stereochemistry of natural kulokekahilide-2. Tetrahedron Lett. 2008, 49, 1163-1165.
-
(2008)
Tetrahedron Lett.
, vol.49
, pp. 1163-1165
-
-
Takada, Y.1
Umehara, M.2
Nakao, Y.3
Kimura, J.4
-
16
-
-
0030576999
-
Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia
-
DOI 10.1016/S0040-4039(96)01464-5
-
Suenaga, K.; Mutou, T.; Shibata, T.; Itoh, T.; Kigoshi, H.; Yamada, K. Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia. Tetrahedron Lett. 1996, 37, 6771-6774. (Pubitemid 26287976)
-
(1996)
Tetrahedron Letters
, vol.37
, Issue.37
, pp. 6771-6774
-
-
Suenaga, K.1
Mutou, T.2
Shibata, T.3
Itoh, T.4
Kigoshi, H.5
Yamada, K.6
-
17
-
-
4444219509
-
Aurilide, a cytotoxic depsipeptide from the sea hare Dolabella auricularia: Isolation, structure determination, synthesis, and biological activity
-
Suenaga, K.; Mutou, T.; Shibata, T.; Itoh, T.; Fujita, T.; Takada, N.; Hayamizu, K.; Takagi, M.; Irifune, T.; Kigoshi, H.; et al. Aurilide, a cytotoxic depsipeptide from the sea hare Dolabella auricularia: Isolation, structure determination, synthesis, and biological activity. Tetrahedron 2004, 60, 8509-8527.
-
(2004)
Tetrahedron
, vol.60
, pp. 8509-8527
-
-
Suenaga, K.1
Mutou, T.2
Shibata, T.3
Itoh, T.4
Fujita, T.5
Takada, N.6
Hayamizu, K.7
Takagi, M.8
Irifune, T.9
Kigoshi, H.10
-
18
-
-
0141675075
-
Solid phase library synthesis of cyclic depsipeptides: Aurilide and aurilide analogues
-
DOI 10.1021/cc020091r
-
Takashi, T.; Nagamiya, H.; Doi, T.; Griffiths, P.G.; Bray, A.M. Solid phase library synthesis of cyclic depsipeptides: aurilide and aurilide analogues. J. Comb. Chem. 2003, 5, 414-428. (Pubitemid 37140553)
-
(2003)
Journal of Combinatorial Chemistry
, vol.5
, Issue.4
, pp. 414-428
-
-
Takahashi, T.1
Nagamiya, H.2
Doi, T.3
Griffiths, P.G.4
Bray, A.M.5
-
19
-
-
47249089015
-
Synthesis and cytotoxicity of aurilide analogs
-
Suenaga, K.; Kajiwara, S.; Kuribayashi, S.; Handa, T.; Kigoshi, H. Synthesis and cytotoxicity of aurilide analogs. Bioorg. Med. Chem. Lett. 2008, 18, 3902-3905.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 3902-3905
-
-
Suenaga, K.1
Kajiwara, S.2
Kuribayashi, S.3
Handa, T.4
Kigoshi, H.5
-
20
-
-
34548833003
-
Reinvestigation of the stereochemistry of kulokekahilide-2
-
DOI 10.1016/j.tetlet.2007.08.093, PII S0040403907017121
-
Takada, Y.; Mori, E.; Umehara, M.; Nakao, Y.; Kimura, J. Reinvestigation of the stereochemistry of kulokekahilide-2. Tetrahedron Lett. 2007, 48, 7653-7656. (Pubitemid 47451484)
-
(2007)
Tetrahedron Letters
, vol.48
, Issue.43
, pp. 7653-7656
-
-
Takada, Y.1
Mori, E.2
Umehara, M.3
Nakao, Y.4
Kimura, J.5
-
21
-
-
82955235549
-
The total synthesis and structure-activity relationships of a highly cytotoxic depsipeptide kulokekahilide-2 and its analogs
-
Takada, Y.; Umehara, M.; Katsumata, R.; Nakao, Y.; Kimura, J. The total synthesis and structure-activity relationships of a highly cytotoxic depsipeptide kulokekahilide-2 and its analogs. Tetrahedron 2012, 68, 659-669.
-
(2012)
Tetrahedron
, vol.68
, pp. 659-669
-
-
Takada, Y.1
Umehara, M.2
Katsumata, R.3
Nakao, Y.4
Kimura, J.5
-
22
-
-
0024382760
-
The p53 proto-oncogene can act as a suppressor of transformation
-
DOI 10.1016/0092-8674(89)90045-7
-
Finlay, C.A.; Hinds, P.W.; Levine, A.J. The p53 proto-oncogene can act as a suppressor of transformation. Cell 1989, 57, 1083-1093. (Pubitemid 19169804)
-
(1989)
Cell
, vol.57
, Issue.7
, pp. 1083-1093
-
-
Finlay, C.A.1
Hinds, P.W.2
Levine, A.J.3
-
23
-
-
9244224723
-
Intrinsic tumour suppression
-
DOI 10.1038/nature03098
-
Lowe, S.W.; Cepero, E.; Evan, G. Intrinsic tumour suppression. Nature 2004, 432, 307-315. (Pubitemid 39551658)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
24
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
DOI 10.1038/sj.onc.1209608, PII 1209608
-
Fulda, S.; Debatin, K.-M. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 2006, 25, 4798-4811. (Pubitemid 44187627)
-
(2006)
Oncogene
, vol.25
, Issue.34
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.-M.2
-
25
-
-
26444489119
-
Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis
-
DOI 10.1126/science.1117105
-
Spierings, D.; McStay, G.; Saleh, M.; Bender, C.; Chipuk, J.; Maurer, U.; Green, D.R. Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis. Science 2005, 310, 66-67. (Pubitemid 41434533)
-
(2005)
Science
, vol.310
, Issue.5745
, pp. 66-67
-
-
Spierings, D.1
McStay, G.2
Saleh, M.3
Bender, C.4
Chipuk, J.5
Maurer, U.6
Green, D.R.7
-
26
-
-
80955122677
-
Systematic chemical mutagenesis identifies a potent novel apratoxin A/E hybrid with improved in vivo antitumor activity
-
Chen, Q.Y.; Liu, Y.; Luesch, H. Systematic chemical mutagenesis identifies a potent novel apratoxin A/E hybrid with improved in vivo antitumor activity. ACS Med. Chem. Lett. 2011, 2, 861-865.
-
(2011)
ACS Med. Chem. Lett.
, vol.2
, pp. 861-865
-
-
Chen, Q.Y.1
Liu, Y.2
Luesch, H.3
-
27
-
-
0033602576
-
Induction of CD95 (Fas) and apoptosis in respiratory epithelial cell cultures following respiratory syncytial virus infection
-
DOI 10.1006/viro.1999.9650
-
O'Donnell, D.R.; Milligan, L.; Stark, J.M. Induction of CD95 (Fas) and apoptosis in respiratory epithelial cell cultures following respiratory syncytial virus infection. Virology 1999, 257, 198-207. (Pubitemid 29391813)
-
(1999)
Virology
, vol.257
, Issue.1
, pp. 198-207
-
-
O'Donnell, D.R.1
Milligan, L.2
Stark, J.M.3
-
28
-
-
40649123558
-
The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8
-
Wrasidlo, W.; Mielgo, A.; Torres, V.A.; Barbero, S.; Stoletov, K.; Suyama, T.L.; Klemke, R.L.; Gerwick, W.H.; Carson, D.A.; Stupack, D.G. The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proc. Nat. Acad. Sci. 2007, 105, 2313-2318.
-
(2007)
Proc. Nat. Acad. Sci.
, vol.105
, pp. 2313-2318
-
-
Wrasidlo, W.1
Mielgo, A.2
Torres, V.A.3
Barbero, S.4
Stoletov, K.5
Suyama, T.L.6
Klemke, R.L.7
Gerwick, W.H.8
Carson, D.A.9
Stupack, D.G.10
-
29
-
-
79251577725
-
Marine natural product aurilide activates the OPA1-mediated apoptosis by binding to prohibitin
-
Sato, S.; Murata, A.; Orihara, T.; Shirakawa, T.; Suenaga, K.; Kigoshi, H.; Uesugi, M. Marine natural product aurilide activates the OPA1-mediated apoptosis by binding to prohibitin. Chem. Biol. 2011, 18, 131-138.
-
(2011)
Chem. Biol.
, vol.18
, pp. 131-138
-
-
Sato, S.1
Murata, A.2
Orihara, T.3
Shirakawa, T.4
Suenaga, K.5
Kigoshi, H.6
Uesugi, M.7
-
30
-
-
17044431001
-
Prohibitin: A potential target for new therapeutics
-
Mishra, S.; Murphy, L.C.; Nyomba, B.L.; Murphy, L.J. Prohibitin: A potential target for new therapeutics. Trends Mol. Med. 2005, 11, 192-197.
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 192-197
-
-
Mishra, S.1
Murphy, L.C.2
Nyomba, B.L.3
Murphy, L.J.4
-
31
-
-
80052366948
-
The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles
-
Ng, K.W.; Khoo, S.P.; Heng, B.C.; Setyawati, M.I.; Tan, E.C.; Zhao, X.; Xiong, S.; Fang, W.; Leong, D.T.; Loo, J.S. The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles. Biomaterials 2011, 32, 8218-8225.
-
(2011)
Biomaterials
, vol.32
, pp. 8218-8225
-
-
Ng, K.W.1
Khoo, S.P.2
Heng, B.C.3
Setyawati, M.I.4
Tan, E.C.5
Zhao, X.6
Xiong, S.7
Fang, W.8
Leong, D.T.9
Loo, J.S.10
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