Lyngbyastatin 4, a dolastatin 13 analogue with elastase and chymotrypsin inhibitory activity from the marine cyanobacterium Lyngbya confervoides

Journal of Natural Products

Volumn 70, Issue 1, 2007, Pages 124-127

  Matthew, Susan ^a   Ross, Cliff ^b   Rocca, James R ^a   Paul, Valerie J ^a   Luesch, Hendrik ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b SMITHSONIAN MARINE STATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMOTRYPSIN; DEPSIPEPTIDE; DOLASTATIN; DOLASTATIN 13; DRUG METABOLITE; ELASTASE; LYNGBYASTATIN 4; SOMAMIDE A; SOMAMIDE B; SYMPLOSTATIN 2; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CYANOBACTERIUM; DRUG INHIBITION; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; IC 50; IN VITRO STUDY; LYNGBYA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

ANIMALS; ATLANTIC OCEAN; CATTLE; CHYMOTRYPSIN; CYANOBACTERIA; DEPSIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLORIDA; MARINE BIOLOGY; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PANCREAS; PANCREATIC ELASTASE; PROTEASE INHIBITORS; SWINE;

ANASPIDEA; CYANOBACTERIA; LYNGBYA CONFERVOIDES;

EID: 33847063427     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np060471k     Document Type: Article

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