Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and Synechococcus

Marine Drugs

Volumn 6, Issue 1, 2008, Pages

  Martins, Rosário F ^a,b,c   Ramos, Miguel F ^a   Herfindal, Lars ^d   Sousa, José A ^a,b   Skærven, Kaja ^d   Vasconcelos, Vitor M ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c POLYTECHNIC INSTITUTE OF PORTO   (Portugal)

^d UNIVERSITY OF BERGEN   (Norway)

Author keywords

Antibiotic; Cytotoxic; Marine cyanobacteria; Synechococcus; Synechocystis

Indexed keywords

ANTIBIOTIC AGENT;

AGAR DIFFUSION; ANIMAL CELL; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CELL STRUCTURE; CONTROLLED STUDY; CYANOBACTERIUM; CYTOTOXICITY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; LIVER CELL; MARINE BACTERIUM; NONHUMAN; RAT; SYNECHOCOCCUS; SYNECHOCYSTIS;

CANDIDA ALBICANS; CELLULOMONAS UDA; CLAVIBACTER MICHIGANENSIS SUBSP. INSIDIOSUS; CYANOBACTERIA; EUKARYOTA; FUNGI; NEGIBACTERIA; POSIBACTERIA; RATTUS; SYNECHOCOCCUS; SYNECHOCYSTIS;

EID: 42149175604     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md6010001     Document Type: Article

References (28)

1. Sponga, F.; Cavaletti, L.; Lazzarini, A.; Borghi, A.; Ciciliato, I.; Losi, D.; Marinelli, F. Biodiversity of potentials of marine-derived microorganisms. J. Biotechnol. 1999, 70, 65-69; DOI: 10.1016/S0168-1656(99)00059-0.
2. Skulberg, O.M. Microalgae as a source of bioactive molecules - experience from cyanophyte research. J. Appl. Phycol. 2000, 12, 341-348; DOI: 10.1023/A:1008140403621.
3. Biondi, N.; Piccardi, R.; Margheri, M.C.; Rodolfi, L.; Smith, G.D.; Tredici, M.R. Evaluation of Nostoc strain ATCC 53789 as a potential source of natural pesticides. Appl. Environ. Microbiol. 2004, 70, 3313-3320; DOI: 10.1128/AEM.70.6.3313-3320.2004;
4. De Philippis, R.; Vincenzini, M. Exocellular polysaccharides from cyanobacteria and their possible applications. FEMS Microbiol. Rev. 1998, 22, 151-175; DOI: 10.1016/S0168-6445(98)00012-6.
5. Mundt, S.; Kreitlow, S.; Nowotny, A.; Effmert, U. Biochemical and pharmacological investigations of selected cyanobacteria. Int. J. Hyg. Environ. Health 2001, 203, 327-334; DOI: 10.1078/1438-4639- 00045;
6. Rao, C.S.V.R. Antimicrobial activity of cyanobacteria. I. J. Mar. Scien. 1994, 23, 55-56.
7. McDermott, C.M.; Nho, C.W.; Howard, W.; Holton, B. The cyanobacterial toxin, Microcystin-LR, can induce apoptosis in a variety of cell types. Toxicon 1998, 36, 1981-1996; DOI: 10.1016/S0041-0101(98) 00128-7;
8. Issa, A.A. Antibiotic production by the cyanobacteria Oscillatoria angustissima and Calothrix parietina. Environ. Toxicol. Pharmacol. 1999, 8, 33-37; DOI: 10.1016/S1382-6689(99)00027-7.
9. Pushparaj, B.; Pelosi, E.; Jüttner, F. Toxicological analysis of the marine cyanobacterium Nodularia harveyana. J. Appl. Phycol. 1999, 10, 527-530; DOI: 10.1023/A:1008080615337.
10. Schlegel, I.; Doan, N.T.; Chazal, N.; Smith, G.D. Antibiotic activity of new cyanobacterial isolates from Australia and Asia against green algae and cyanobacteria. J. Appl. Phycol. 1999, 10, 471-479; DOI: 10.1023/A:1008042619686.
11. Schaeffer, D.J.; Krylov, V.S. Anti-HIV activity of extracts and compounds from algae and cyanobacteria. Ecotoxicol. Environ. Saf. 2000, 45, 208-227; DOI: 10.1006/eesa.1999.1862;
12. Suikkanen, S.; Fistarol, G.O.; Granéli, E. Allelopathic effects of the Baltic Cyanobacteria Nodularia spumigena, Aphanizomenon flos-aquae and Anabaena lemmermannii on algal monocultures. J. Exp. Mar. Biol. Ecol. 2004, 308, 85-101; DOI: 10.1016/j.jembe.2004.02.012.
13. Kotai, J. Instructions for preparation of modified nutrient solution Z8 for algae. Norwegian Institute for Water Research, B-11769, Blindern, Oslo, 1972.
14. Kreitlow, S.; Mundt, S.; Lindequist, U. Cyanobacteria - a potential source of new biologically active substances. J. Biotechnol. 1999, 70, 61-63; DOI: 10.1016/S0168-1656(99)00058-9;
15. Bauer, A.W.; Kirby, W.M.M.; Sherris, J.C.; Turck, M. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 1966, 45, 493-496;
16. Mellgren, G.; Vintermyr, O.; Døskeland, S.O. Okadaic acid, cAMP, and selected nutrients inhibit hepatocyte proliferation at different stages in G1: modulation of the cAMP effect by phosphatase inhibitors and nutrients. J. Cell Physiol. 1995, 163, 232-240; DOI: 10.1002/jcp. 1041630203;
17. Gerwick, W.H.; Proteau, P.J.; Nagle, D.G.; Hamel, E.; Blokhin, A.; Slate, D.L. Structure of curacin A, a novel antimitotic, antiproliferative, and brine shrimp toxic natural product from the marine cyanobacterium Lyngbya majuscula. J. Org. Chem. 1994, 59, 1243-1245; DOI: 10.1021/jo00085a006.
18. Mayer, A.M.S.; Gustafson, K.R. Marine pharmacology in 2000: antitumor and cytotoxic compounds. Int. J. Cancer 2003, 105, 291-299; DOI: 10.1002/ijc.11080;
19. Shimizu, Y. Microalgal metabolites. Curr. Opin. Microbiol. 2003, 6, 236-243; DOI: 10.1016/S1369-5274(03)00064-X;
20. Fladmark, K.E.; Serres, M.H.; Larsen, N.L.; Yasumoto, T.; Aune, T.; Døskeland, S.O. Sensitive detection of apoptogenic toxins in suspension cultures of rat and salmon hepatocytes. Toxicon 1998, 36, 1101-1114; DOI: 10.1016/S0041-0101(98)00083-X;
21. Humpage, A.R.; Falconer, I.R. Microcystin-LR and liver tumor promotion: effects on cytokinesis, ploidy, and apoptosis in cultured hepatocytes. Environ. Toxicol. 1999, 14, 61-75; DOI: 10.1002/(SICI)1522-7278(199902)14:1〈61::AID-TOX10〉3.0.CO;2-R.
22. Mankiewicz, J.; Tarczynska, M.; Fladmark, K.E.; Døskeland, S.O.; Walter, Z.; Zalewski, M. Apoptotic effects of cyanobacterial extract on rat hepatocytes and human lymphocytes. Environ. Toxicol. 2001, 16, 225-233; DOI: 10.1002/tox.1028;
23. Bironaite, D.; Siegel, D.; Moran, J.L.; Weksler, B.B.; Ross, D. Stimulation of endothelial IL-8 (eIL-8) production and apoptosis by phenolic metabolites of benzene in HL-60 cells and human bone marrow endothelial cells. Chem. Biol. Interact. 2004, 149, 37-49; DOI: 10.1016/j.cbi.2004.06.004;
24. Poncet, J. The dolastatins, a family of promising antineoplastic agents. Curr. Pharm. Des. 1999, 5, 139-162;
25. Da Rocha, A.B.; Lopes, R.; Schwartsmann, G. Natural products in anticancer therapy. Curr. Opin. Pharmacol. 2001, 1, 364-369; DOI: 10.1016/S1471-4892(01)00063-7;
26. Østensvik, Ø.; Skulberg, O.M.; Underdal, B.; Hormazabal, V. Antibacterial properties of extracts from selected planktonic freshwater cyanobacteria - a comparative study of bacterial bioassays. J. Appl. Microbiol. 1998, 84, 1117-1124;
27. Dixon, R.A.; Al-Zazawi, M.; Alderson, G. Permeabilising effects of sub-inhibitory concentrations of microcystin on the growth of Escherichia coli. FEMS Microbiol. Lett. 2004, 230, 167-170; DOI: 10.1016/S0378-1097(03)00910-8;
28. Moore, R.E.; Patterson, G.M.L.; Carmichael, W.W. New pharmaceuticals from cultured bluegreen algae. In Biomedical importance of marine organisms; Fautin, D.G., Ed.; Mem. Cal. Acad. Sci., 1988; Volume 13, pp. 143-150.