Treatment of human prostate cancer cells with dolastatin 10, a peptide isolated from a marine shell-less mollusc

Prostate

Volumn 34, Issue 3, 1998, Pages 175-181

  Turner, Timothy ^a   Jackson, William H ^b   Pettit, George R ^c   Wells, Alan ^a   Kraft, Andrew S ^b,d  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c ARIZONA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Dolastatin 10; EGF receptor; Prostate cancer; Tubulin

Indexed keywords

DOLASTATIN 10;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CYTOPATHOGENIC EFFECT; DEPOLYMERIZATION; DRUG EFFECT; DRUG ISOLATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROSTATE CANCER;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DIVISION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR STRUCTURE; MOLLUSCA; OLIGOPEPTIDES; PROSTATIC NEOPLASMS; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0031960723     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19980215)34:3<175::AID-PROS4>3.0.CO;2-H     Document Type: Article

References (11)

1. Steube KG, Gruncicke D, Pietsch T, Gignac SM, Pettit GR, Drexler HG: Dolastatin 10 and dolastatin 15: Effects of two natural peptides on growth and differentiation of leukemia cells. Leukemia 1992;6:1048-1053.
2. Beckwith M, Urba WJ, Longo DL: Growth inhibition of human lymphoma cell lines by the marine products, dolastatins 10 and 15. J Natl Cancer Inst 1993;85:483-488.
3. Pettit GR, Kamano Y, Herald CL, Tuinman AA, Boettner FE, Kizu H, Schmidt JM, Baczynskyj L, Tomer KB, Bontems RJ: The isolation and structure of a remarkable marine animal antineoplastic constituent: Dolastatin 10. J Am Chem Soc 1987;109: 6883-6885.
4. Li Y, Kobayaski H, Hashimoto Y, Shirai R, Hirata A, Hayashi K, Hamada Y, Shiori T, Iwasaki S: Interaction of the marine toxin dolastatin 10 with porcine brain tubulin: Competitive inhibition of rhizoxin and phomopsin A binding. Chem Biol Interact 1994; 93:175-183.
5. Bai R, Pettit GR, Hamel E: Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Biochem Pharmacol 1990;39:1941-1949.
6. Bai R, Pettit GH, Hamel E: Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. J Biol Chem 1990;265: 17141-17149.
7. Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Luduena RF, Hamel E: Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Biochem Pharmacol 1993;45:1503-1515.
8. Toppmeyer DL, Slapak CA, Croop J, Kufe DW: Role of P-glycoprotein in dolastatin 10 resistance. Biochem Pharmacol 1994;48:609-612.
9. Stone KR, Mickey DD, Wunderli H, Mickey GH, Paulson DF: Isolation of a human prostate carcinoma cell line (DU-145). Int J Cancer 1978;21:274-281.
10. Turner T, Chen P, Goodly LJ, Wells A: EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells. Clin Exp Metastasis 1996;14:409-418.
11. Xie H, Turner T, Wang M-H, Singh RK, Siegal GP, Wells A: In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals. Clin Exp Metastasis 1995;13:407-419.