The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 7, 2008, Pages 2313-2318

  Wrasidlo, Wolf ^b   Mielgo, Ainhoa ^a,b   Torres, Vicente A ^a,b   Barbero, Simone ^a,b   Stoletov, Konstantin ^a,b   Suyama, Takashi L ^d   Klemke, Richard L ^a,b   Gerwick, William H ^b,c,d   Carson, Dennis A ^b   Stupack, Dwayne G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Angiogenesis; Cancer; Nanoparticle

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CASPASE 8; CERAMIDE; LIPOPEPTIDE; LIPOSOME; SMALL INTERFERING RNA; SOMOCYSTINAMIDE A; UNCLASSIFIED DRUG; DISULFIDE; LIPOPROTEIN; PHOSPHOLIPID;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CHORIOALLANTOIS; DRUG MECHANISM; DRUG SCREENING; ENDOTHELIUM CELL; ENZYME LOCALIZATION; IN VITRO STUDY; INHIBITION KINETICS; MARINE SPECIES; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TUMOR CELL; TUMOR GROWTH; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CHICKEN; DRUG EFFECT; HUMAN; METABOLISM; PRENATAL DEVELOPMENT; SEA; SENSITIVITY AND SPECIFICITY; TRANSGENIC ANIMAL; TUMOR CELL LINE; VASCULARIZATION;

DANIO RERIO;

ANGIOGENESIS INHIBITORS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; CASPASE 8; CELL LINE, TUMOR; CELL MEMBRANE; CHICKENS; DISULFIDES; EMBRYO, NONMAMMALIAN; HUMANS; LIPOPROTEINS; MOLECULAR STRUCTURE; OCEANS AND SEAS; PHOSPHOLIPIDS; SENSITIVITY AND SPECIFICITY;

EID: 40649123558     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0712198105     Document Type: Article

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