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Journal of the American Chemical Society

Volumn 123, Issue 23, 2001, Pages 5418-5423

Total structure determination of apratoxin A, a potent novel cytotoxin from the marine cyanobacterium Lyngbya majuscula

(5) Luesch, H a Yoshida, W Y a Moore, R E a Paul, V J b Corbett, T H c

a UNIVERSITY OF HAWAII (United States)

b UNIVERSITY OF GUAM MARINE LABORATORY (Guam)

c WAYNE STATE UNIVERSITY (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MODELING;

BACTERIA; COMPUTATIONAL GEOMETRY; DRUG PRODUCTS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONCOLOGY; TOXIC MATERIALS;

PROTEINS;

3,7 DIHYDROXY 2,5,8,8 TETRAMETHYLNONANOIC ACID; AMINO ACID; APRATOXIN A; CYTOTOXIN; FATTY ACID; ORGANIC COMPOUND; POLYKETIDE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; CANCER CELL CULTURE; CHIRAL CHROMATOGRAPHY; CYANOBACTERIUM; CYTOPATHOGENIC EFFECT; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; LYNGBYA MAJUSCULA; METHYLATION; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; STEREOCHEMISTRY;

ADENOCARCINOMA; ANIMALS; BACTERIAL TOXINS; BREAST NEOPLASMS; CELL SURVIVAL; COLONIC NEOPLASMS; CYANOBACTERIA; CYTOTOXINS; DEPSIPEPTIDES; FEMALE; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MARINE TOXINS; MICE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDES, CYCLIC; TUMOR CELLS, CULTURED;

EID: 0034833620 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja010453j Document Type: Article

Times cited : (339)

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