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Volumn 56, Issue 11, 2015, Pages 6404-6413

Effects of inflammasome activation on secretion of inflammatory cytokines and vascular endothelial growth factor by retinal pigment epithelial cells

Author keywords

Interleukin 1 ; Interleukin 18; Microglia cells; NLRP3 inflammasome; Vascular endothelial cells

Indexed keywords

CRYOPYRIN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LEUCYLLEUCINE METHYL ESTER; LIPOFUSCIN; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; VASCULOTROPIN; VASCULOTROPIN A;

EID: 84943644227     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16898     Document Type: Article
Times cited : (28)

References (49)
  • 2
    • 84863845318 scopus 로고    scopus 로고
    • Mechanisms of age-related maculardegeneration
    • Ambati J, Fowler BJ. Mechanisms of age-related maculardegeneration. Neuron. 2012;75:26-39.
    • (2012) Neuron , vol.75 , pp. 26-39
    • Ambati, J.1    Fowler, B.J.2
  • 3
    • 37449010146 scopus 로고    scopus 로고
    • The natural historyand prognosis of neovascular age-related macular degeneration:A systematic review of the literature and meta-analysis
    • Wong TY, Wong T, Chakravarthy U, et al. The natural historyand prognosis of neovascular age-related macular degeneration:a systematic review of the literature and meta-analysis. Ophthalmology. 2008;115:116-126.
    • (2008) Ophthalmology , vol.115 , pp. 116-126
    • Wong, T.Y.1    Wong, T.2    Chakravarthy, U.3
  • 4
    • 18044366931 scopus 로고    scopus 로고
    • RPE lipofuscin and its role in retinal pathobiology
    • Sparrow JR, Boulton M. RPE lipofuscin and its role in retinal pathobiology. Exp Eye Res. 2005;80:595-606.
    • (2005) Exp Eye Res , vol.80 , pp. 595-606
    • Sparrow, J.R.1    Boulton, M.2
  • 5
    • 10044255422 scopus 로고    scopus 로고
    • Lipids and lipidperoxidation products in the pathogenesis of age-relatedmacular degeneration
    • Kopitz J, Holz FG, Kaemmerer E, Schutt F. Lipids and lipidperoxidation products in the pathogenesis of age-relatedmacular degeneration. Biochimie. 2004;86:825-831.
    • (2004) Biochimie , vol.86 , pp. 825-831
    • Kopitz, J.1    Holz, F.G.2    Kaemmerer, E.3    Schutt, F.4
  • 7
    • 0034832029 scopus 로고    scopus 로고
    • An integrated hypothesis that considers drusen asbiomarkers of immune-mediated processes at the RPE-Bruch’s membrane interface in aging and age-related macular degeneration
    • Hageman G. An integrated hypothesis that considers drusen asbiomarkers of immune-mediated processes at the RPE-Bruch’s membrane interface in aging and age-related macular degeneration. Prog Retin Eye Res. 2001;20:705-732.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 705-732
    • Hageman, G.1
  • 8
    • 49749150467 scopus 로고    scopus 로고
    • Systemic complement activation in age-related macular degeneration
    • Scholl HPN, Charbel Issa P, Walier M, et al. Systemic complement activation in age-related macular degeneration. PLoS One. 2008;3: 2593.
    • (2008) Plos One , vol.3 , pp. 2593
    • Scholl, H.1    Charbel Issa, P.2    Walier, M.3
  • 9
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol. 2002;134:411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 10
    • 84874524481 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: Implications for age-related macular degeneration
    • Tseng WA, Thein T, Kinnunen K, et al. NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013;54:110-120.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 110-120
    • Tseng, W.A.1    Thein, T.2    Kinnunen, K.3
  • 11
    • 84860883878 scopus 로고    scopus 로고
    • DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3inflammasome and MyD88
    • Tarallo V, Hirano Y, Gelfand BD, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3inflammasome and MyD88. Cell. 2012;149:847-859.
    • (2012) Cell , vol.149 , pp. 847-859
    • Tarallo, V.1    Hirano, Y.2    Gelfand, B.D.3
  • 12
    • 84929377477 scopus 로고    scopus 로고
    • Interleukin-1b level is increased in vitreous of patients with neovascular age-related macular degeneration (NAMD) and polypoidal choroidal vasculopathy(PCV)
    • Zhao M, Bai Y, Xie W, et al. Interleukin-1b level is increased in vitreous of patients with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vasculopathy(PCV). PLoS One. 2015;10: 0125150.
    • (2015) Plos One , vol.10 , pp. 0125150
    • Zhao, M.1    Bai, Y.2    Xie, W.3
  • 13
    • 84919791561 scopus 로고    scopus 로고
    • Interleukin-18 induces retinalpigment epithelium degeneration in mice
    • Ijima R, Kaneko H, Ye F, et al. Interleukin-18 induces retinalpigment epithelium degeneration in mice. Invest OphthalmolVis Sci. 2014;55:6673-6678.
    • (2014) Invest Ophthalmolvis Sci , vol.55 , pp. 6673-6678
    • Ijima, R.1    Kaneko, H.2    Ye, F.3
  • 14
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140: 821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 16
    • 84937973081 scopus 로고    scopus 로고
    • Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage
    • Brandstetter C, Mohr LKM, Latz E, Holz FG, Krohne TU. Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage. J Mol Med. 2015;93:905-916.
    • (2015) J Mol Med , vol.93 , pp. 905-916
    • Brandstetter, C.1    Mohr, L.2    Latz, E.3    Holz, F.G.4    Krohne, T.U.5
  • 17
    • 84860671364 scopus 로고    scopus 로고
    • NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components
    • Doyle SL, Campbell M, Ozaki E, et al. NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components. Nat Med. 2012;18:791-798.
    • (2012) Nat Med , vol.18 , pp. 791-798
    • Doyle, S.L.1    Campbell, M.2    Ozaki, E.3
  • 18
    • 80054879752 scopus 로고    scopus 로고
    • Regulation of VEGF expression in human retinal cells by cytokines: Implications for the role of inflammation in agerelated macular degeneration
    • Nagineni CN, Kommineni VK, William A, Detrick B, Hooks JJ. Regulation of VEGF expression in human retinal cells by cytokines: implications for the role of inflammation in agerelated macular degeneration. J Cell Physiol. 2012;227:116-126.
    • (2012) J Cell Physiol , vol.227 , pp. 116-126
    • Nagineni, C.N.1    Kommineni, V.K.2    William, A.3    Detrick, B.4    Hooks, J.J.5
  • 19
    • 79959191436 scopus 로고    scopus 로고
    • Interleukin-1beta inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration
    • Lavalette S, Raoul W, Houssier M, et al. Interleukin-1beta inhibition prevents choroidal neovascularization and does not exacerbate photoreceptor degeneration. Am J Pathol. 2011; 178:2416-2423.
    • (2011) Am J Pathol , vol.178 , pp. 2416-2423
    • Lavalette, S.1    Raoul, W.2    Houssier, M.3
  • 20
    • 77649188326 scopus 로고    scopus 로고
    • Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells
    • Krohne TU, Stratmann NK, Kopitz J, Holz FG. Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells. Exp Eye Res. 2010;90: 465-471.
    • (2010) Exp Eye Res , vol.90 , pp. 465-471
    • Krohne, T.U.1    Stratmann, N.K.2    Kopitz, J.3    Holz, F.G.4
  • 21
    • 77955908261 scopus 로고    scopus 로고
    • Generation of microglial cells from mouse embryonic stem cells
    • Beutner C, Roy K, Linnartz B, Napoli I, Neumann H. Generation of microglial cells from mouse embryonic stem cells. Nat Protoc. 2010;5:1481-1494.
    • (2010) Nat Protoc , vol.5 , pp. 1481-1494
    • Beutner, C.1    Roy, K.2    Linnartz, B.3    Napoli, I.4    Neumann, H.5
  • 22
    • 77649168211 scopus 로고    scopus 로고
    • Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action
    • Krohne TU, Kaemmerer E, Holz FG, Kopitz J. Lipid peroxidation products reduce lysosomal protease activities in human retinal pigment epithelial cells via two different mechanisms of action. Exp Eye Res. 2010;90:261-266.
    • (2010) Exp Eye Res , vol.90 , pp. 261-266
    • Krohne, T.U.1    Kaemmerer, E.2    Holz, F.G.3    Kopitz, J.4
  • 23
    • 75749135738 scopus 로고    scopus 로고
    • Apical-to-basolateral transcytosis of photoreceptor outer segments induced by lipid peroxidation products in human retinal pigment epithelial cells
    • Krohne TU, Holz FG, Kopitz J. Apical-to-basolateral transcytosis of photoreceptor outer segments induced by lipid peroxidation products in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2010;51:553-560.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 553-560
    • Krohne, T.U.1    Holz, F.G.2    Kopitz, J.3
  • 24
    • 0034868947 scopus 로고    scopus 로고
    • Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro
    • Krohne TU, Shankara S, Geissler M, et al. Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro. Hepatology. 2001;34:511-518.
    • (2001) Hepatology , vol.34 , pp. 511-518
    • Krohne, T.U.1    Shankara, S.2    Geissler, M.3
  • 25
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang C-C, Park AY, Guan J-L. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc. 2007;2:329-333.
    • (2007) Nat Protoc , vol.2 , pp. 329-333
    • Liang, C.-C.1    Park, A.Y.2    Guan, J.-L.3
  • 26
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals andaluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A, et al. Silica crystals andaluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008;9:847-856.
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3
  • 27
    • 70449732756 scopus 로고    scopus 로고
    • The role of macrophagederivedIL-1 in induction and maintenance of angiogenesi
    • Carmi Y, Voronov E, Dotan S, et al. The role of macrophagederivedIL-1 in induction and maintenance of angiogenesis. J Immunol. 2009;183:4705-4714.
    • (2009) J Immuno , vol.18 , pp. 4705-5471
    • Carmi, Y.1    Voronov, E.2    Dotan, S.3
  • 28
    • 84888014482 scopus 로고    scopus 로고
    • Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration
    • Cao S, Ko A, Partanen M, et al. Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration. Am JOphthalmol. 2013;156:1176-1183.
    • (2013) Am Jophthalmol , vol.156 , pp. 1176-1183
    • Cao, S.1    Ko, A.2    Partanen, M.3
  • 29
    • 84904917944 scopus 로고    scopus 로고
    • Vinpocetine inhibits amyloid-beta induced activation of NF-jB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells
    • Liu RT, Wang A, To E, et al. Vinpocetine inhibits amyloid-beta induced activation of NF-jB, NLRP3 inflammasome and cytokine production in retinal pigment epithelial cells. Exp Eye Res. 2014;127:49-58.
    • (2014) Exp Eye Res , vol.127 , pp. 49-58
    • Liu, R.T.1    Wang, A.2    To, E.3
  • 30
    • 84879540747 scopus 로고    scopus 로고
    • A2E induces IL-1b production in retinal pigment epithelial cells via the NLRP3 inflammasome
    • Anderson OA, Finkelstein A, Shima DT. A2E induces IL-1b production in retinal pigment epithelial cells via the NLRP3 inflammasome. PLoS One. 2013;8: 67263.
    • (2013) Plos One , vol.8 , pp. 67263
    • Anderson, O.A.1    Finkelstein, A.2    Shima, D.T.3
  • 31
    • 84865369140 scopus 로고    scopus 로고
    • SalminenA, Kaarniranta K. Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells-implications for age-related macular degeneration (AMD)
    • Kauppinen A, Niskanen H, Suuronen T, Kinnunen K, SalminenA, Kaarniranta K. Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells-implications for age-related macular degeneration (AMD). Immunol Lett. 2012;147:29-33.
    • (2012) Immunol Lett , vol.147 , pp. 29-33
    • Kauppinen, A.1    Niskanen, H.2    Suuronen, T.3    Kinnunen, K.4
  • 33
    • 0035879852 scopus 로고    scopus 로고
    • Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells
    • Davies S, Elliott MH, Floor E, et al. Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells. Free Radic Biol Med. 2001;31:256-265.
    • (2001) Free Radic Biol Med , vol.31 , pp. 256-265
    • Davies, S.1    Elliott, M.H.2    Floor, E.3
  • 34
    • 0026553503 scopus 로고
    • Interleukin-6 (IL-6) gene expression and secretion by cytokine-stimulated human retinal pigment epithelial cells
    • Elner VM, Scales W, Elner SG, Danforth J, Kunkel SL, Strieter RM. Interleukin-6 (IL-6) gene expression and secretion by cytokine-stimulated human retinal pigment epithelial cells. Exp Eye Res. 1992;54:361-368.
    • (1992) Exp Eye Res , vol.54 , pp. 361-368
    • Elner, V.M.1    Scales, W.2    Elner, S.G.3    Danforth, J.4    Kunkel, S.L.5    Strieter, R.M.6
  • 35
    • 0026672276 scopus 로고
    • Production of interleukin-6 by human retinal pigment epithelium in vitro and its regulation by other cytokines
    • Benson MT, Shepherd L, Rees RC, Rennie IG. Production of interleukin-6 by human retinal pigment epithelium in vitro and its regulation by other cytokines. Curr Eye Res. 1992; 11:173-179.
    • (1992) Curr Eye Res , vol.11 , pp. 173-179
    • Benson, M.T.1    Shepherd, L.2    Rees, R.C.3    Rennie, I.G.4
  • 36
    • 0032950638 scopus 로고    scopus 로고
    • Cytokine regulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production by human retinal pigment epithelial cells
    • Crane IJ, Kuppner MC, McKillop-Smith S, Wallace CA, Forrester JV. Cytokine regulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production by human retinal pigment epithelial cells. Clin Exp Immunol. 1999; 115:288-293.
    • (1999) Clin Exp Immunol , vol.115 , pp. 288-293
    • Crane, I.J.1    Kuppner, M.C.2    McKillop-Smith, S.3    Wallace, C.A.4    Forrester, J.V.5
  • 37
    • 0027176576 scopus 로고
    • Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells
    • Jaffe GJ, Richmond A, Van Le L, et al. Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1993;34:2776-2785.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 2776-2785
    • Jaffe, G.J.1    Richmond, A.2    Van Le, L.3
  • 38
    • 77953434480 scopus 로고    scopus 로고
    • Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration
    • Sonoda S, Sreekumar PG, Kase S, et al. Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: relevance to age-related macular degeneration. Aging (Albany NY). 2010;2:28-42.
    • (2010) Aging (Albany NY) , vol.2 , pp. 28-42
    • Sonoda, S.1    Sreekumar, P.G.2    Kase, S.3
  • 39
    • 84899078505 scopus 로고    scopus 로고
    • IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration
    • Doyle SL, Ozaki E, Brennan K, et al. IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration. Sci Transl Med. 2014;6:230-44.
    • (2014) Sci Transl Med , vol.6 , pp. 230-244
    • Doyle, S.L.1    Ozaki, E.2    Brennan, K.3
  • 40
    • 62549142650 scopus 로고    scopus 로고
    • Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling
    • Leung KW, Barnstable CJ, Tombran-Tink J. Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling. Mol Immunol. 2009;46:1374-1386.
    • (2009) Mol Immunol , vol.46 , pp. 1374-1386
    • Leung, K.W.1    Barnstable, C.J.2    Tombran-Tink, J.3
  • 41
    • 84873356026 scopus 로고    scopus 로고
    • Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells
    • Juel HB, Faber C, Udsen MS, Folkersen L, Nissen MH. Chemokine expression in retinal pigment epithelial ARPE-19 cells in response to coculture with activated T cells. Invest Ophthalmol Vis Sci. 2012;53:8472-8480.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 8472-8480
    • Juel, H.B.1    Faber, C.2    Udsen, M.S.3    Folkersen, L.4    Nissen, M.H.5
  • 42
    • 53449084910 scopus 로고    scopus 로고
    • Control of chemokine gradients by the retinal pigment epithelium
    • Shi G, Maminishkis A, Banzon T, et al. Control of chemokine gradients by the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2008;49:4620-4630.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4620-4630
    • Shi, G.1    Maminishkis, A.2    Banzon, T.3
  • 44
    • 34948898131 scopus 로고    scopus 로고
    • CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration
    • Combadiére C, Feumi C, Raoul W, et al. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest. 2007;117:2920-2928.
    • (2007) J Clin Invest , pp. 2920-2928
    • Combadiére, C.1    Feumi, C.2    Raoul, W.3
  • 45
    • 84887096324 scopus 로고    scopus 로고
    • CCR2(þ) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice
    • Sennlaub F, Auvynet C, Calippe B, et al. CCR2(þ) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice. EMBO Mol Med. 2013;5:1775-1793.
    • (2013) EMBO Mol Med , vol.5 , pp. 1775-1793
    • Sennlaub, F.1    Auvynet, C.2    Calippe, B.3
  • 46
    • 0037375042 scopus 로고    scopus 로고
    • Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and agerelated macular degeneration
    • Gupta N, Brown KE, Milam AH. Activated microglia in human retinitis pigmentosa, late-onset retinal degeneration, and agerelated macular degeneration. Exp Eye Res. 2003;76:463-471.
    • (2003) Exp Eye Res , vol.76 , pp. 463-471
    • Gupta, N.1    Brown, K.E.2    Milam, A.H.3
  • 47
    • 84909605289 scopus 로고    scopus 로고
    • IL-18 is not therapeutic for neovascular age-related macular degeneration
    • Hirano Y, Yasuma T, Mizutani T, et al. IL-18 is not therapeutic for neovascular age-related macular degeneration. Nat Med. 2014;20:1372-1375.
    • (2014) Nat Med , vol.20 , pp. 1372-1375
    • Hirano, Y.1    Yasuma, T.2    Mizutani, T.3
  • 48
    • 45549107669 scopus 로고    scopus 로고
    • A2E, a pigment of the lipofuscin of retinal pigment epithelial cells, is an endogenous ligand for retinoic acid receptor
    • Iriyama A, Fujiki R, Inoue Y, et al. A2E, a pigment of the lipofuscin of retinal pigment epithelial cells, is an endogenous ligand for retinoic acid receptor. J Biol Chem. 2008;283: 11947-11953.
    • (2008) J Biol Chem , vol.283 , pp. 11947-11953
    • Iriyama, A.1    Fujiki, R.2    Inoue, Y.3
  • 49
    • 15244351557 scopus 로고    scopus 로고
    • Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells
    • Zhou J, Cai B, Jang YP, Pachydaki S, Schmidt AM, Sparrow JR. Mechanisms for the induction of HNE- MDA- and AGE-adducts, RAGE and VEGF in retinal pigment epithelial cells. Exp Eye Res. 2005;80:567-580.
    • (2005) Exp Eye Res , vol.80 , pp. 567-580
    • Zhou, J.1    Cai, B.2    Jang, Y.P.3    Pachydaki, S.4    Schmidt, A.M.5    Sparrow, J.R.6


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