Relationship between systemic cytokines and complement factor H Y402H polymorphism in patients with dry age-related macular degeneration

American Journal of Ophthalmology

Volumn 156, Issue 6, 2013, Pages 1176-1183

  Cao, Sijia ^a   Ko, Ashley ^a   Partanen, Marita ^a   Pakzad Vaezi, Kaivon ^a   Merkur, Andrew B ^a   Albiani, David A ^a   Kirker, Andrew W ^a   Wang, Aikun ^a   Cui, Jing Z ^a   Forooghian, Farzin ^a   Matsubara, Joanne A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT FACTOR H; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

AGED; ARTICLE; CHOROID; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE COURSE; DNA POLYMORPHISM; DRUSEN; GENOTYPE; HUMAN; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; THICKNESS;

AGED; CHOROID; COMPLEMENT FACTOR H; CROSS-SECTIONAL STUDIES; CYTOKINES; DIAGNOSTIC TECHNIQUES, OPHTHALMOLOGICAL; GENOTYPING TECHNIQUES; GEOGRAPHIC ATROPHY; HUMANS; PILOT PROJECTS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RETINAL DRUSEN; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84888014482     PISSN: 00029394     EISSN: 18791891     Source Type: Journal    
DOI: 10.1016/j.ajo.2013.08.003     Document Type: Article

References (51)

1. S. Resnikoff, D. Pascolini, and D. Etya'ale Global data on visual impairment in the year 2002 Bull World Health Organ 82 11 2004 844 851
2. R.D. Jager, W.F. Mieler, and J.W. Miller Age-related macular degeneration N Engl J Med 358 24 2008 2606 2617
3. R. Klein, B.E. Klein, M.D. Knudtson, S.M. Meuer, M. Swift, and R.E. Gangnon Fifteen-year cumulative incidence of age-related macular degeneration: the Beaver Dam Eye Study Ophthalmology 114 2 2007 253 262
4. D.S. McLeod, R. Grebe, I. Bhutto, C. Merges, T. Baba, and G.A. Lutty Relationship between RPE and choriocapillaris in age-related macular degeneration Invest Ophthalmol Vis Sci 50 10 2009 4982 4991
5. R.F. Mullins, M.N. Johnson, E.A. Faidley, J.M. Skeie, and J. Huang Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration Invest Ophthalmol Vis Sci 52 3 2011 1606 1612
6. S.W. Kim, J. Oh, S.S. Kwon, J. Yoo, and K. Huh Comparison of choroidal thickness among patients with healthy eyes, early age-related maculopathy, neovascular age-related macular degeneration, central serous chorioretinopathy, and polypoidal choroidal vasculopathy Retina 31 9 2011 1904 1911
7. G. Gregori, F. Wang, and P.J. Rosenfeld Spectral domain optical coherence tomography imaging of drusen in nonexudative age-related macular degeneration Ophthalmology 118 7 2011 1373 1379
8. V. Manjunath, J. Goren, J.G. Fujimoto, and J.S. Duker Analysis of choroidal thickness in age-related macular degeneration using spectral-domain optical coherence tomography Am J Ophthalmol 152 4 2011 663 668
9. Z. Yehoshua, P.J. Rosenfeld, G. Gregori, and F. Penha Spectral domain optical coherence tomography imaging of dry age-related macular degeneration Ophthalmic Surg Lasers Imaging 41 Suppl 2010 S6 S14
10. R.E. Gangnon, K.E. Lee, B.E. Klein, S.K. Iyengar, T.A. Sivakumaran, and R. Klein Effect of the Y402H variant in the complement factor H gene on the incidence and progression of age-related macular degeneration: results from multistate models applied to the Beaver Dam Eye Study Arch Ophthalmol 130 9 2012 1169 1176
11. D. Weismann, K. Hartvigsen, and N. Lauer Complement factor H binds malondialdehyde epitopes and protects from oxidative stress Nature 478 7367 2011 76 81
12. P.X. Shaw, L. Zhang, and M. Zhang Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids Proc Natl Acad Sci U S A 109 34 2012 13757 13762
13. H.P. Scholl, P. Charbel Issa, and M. Walier Systemic complement activation in age-related macular degeneration PloS One 3 7 2008 e2593
14. D. Smailhodzic, C.C. Klaver, and B.J. Klevering Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration Ophthalmology 119 2 2012 339 346
15. B. Liu, L. Wei, and C. Meyerle Complement component C5a promotes expression of IL-22 and IL-17 from human T cells and its implication in age-related macular degeneration J Transl Med 9 2011 1 12
16. X. Zhang, Y. Kimura, and C. Fang Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo Blood 110 1 2007 228 236
17. J.M. Seddon, S. George, B. Rosner, and N. Rifai Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers Arch Ophthalmol 123 6 2005 774 782
18. J.B. Jonas, Y. Tao, M. Neumaier, and P. Findeisen Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration Acta Ophthalmol 90 5 2012 e381 e388
19. H. Oh, H. Takagi, and C. Takagi The potential angiogenic role of macrophages in the formation of choroidal neovascular membranes Invest Ophthalmol Vis Sci 40 9 1999 1891 1898
20. T. Lin, G.B. Walker, and K. Kurji Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: implications for age-related degenerative diseases of the eye Cytokine 62 3 2013 369 381
21. S.W. Cousins, D.G. Espinosa-Heidmann, and K.G. Csaky Monocyte activation in patients with age-related macular degeneration: a biomarker of risk for choroidal neovascularization? Arch Ophthalmol 122 7 2004 1013 1018
22. V. Tarallo, Y. Hirano, and B.D. Gelfand DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 Cell 149 4 2012 847 859
23. S.L. Doyle, M. Campbell, and E. Ozaki NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components Nat Med 18 5 2012 791 798
24. J.C.C. Wang, A. Wang, and J. Gao Isolation of total DNA from postmortem human eye tissues and quality comparison between iris and retina Mol Vis 18 311 2012 3049 3056
25. A. Ko, S. Cao, and K. Pakzad-Vaezi Optical coherence tomography-based correlation between choroidal thickness and drusen load in dry age-related macular degeneration Retina 33 5 2013 1005 1010
26. W.B. Ershler, W.H. Sun, and N. Binkley Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction Lymphokine Cytokine Res 12 4 1993 225 230
27. W.B. Ershler, and E.T. Keller Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty Annu Rev Med 51 2000 245 270
28. L. Rink, I. Cakman, and H. Kirchner Altered cytokine production in the elderly Mech Ageing Dev 102 2-3 1998 199 209
29. S.D. Bamforth, S. Lightman, and J. Greenwood The effect of TNF-alpha and IL-6 on the permeability of the rat blood-retinal barrier in vivo Acta Neuropathol 91 6 1996 624 632
30. S.D. Bamforth, S.L. Lightman, and J. Greenwood Ultrastructural analysis of interleukin-1 beta-induced leukocyte recruitment to the rat retina Invest Ophthalmol Vis Sci 38 1 1997 25 35
31. A. Duchini, S. Govindarajan, M. Santucci, G. Zampi, and F.M. Hofman Effects of tumor necrosis factor-alpha and interleukin-6 on fluid-phase permeability and ammonia diffusion in CNS-derived endothelial cells J Investig Med 44 8 1996 474 482
32. S.G. Elner, R.M. Strieter, V.M. Elner, B.J. Rollins, M.A. Del Monte, and S.L. Kunkel Monocyte chemotactic protein gene expression by cytokine-treated human retinal pigment epithelial cells Lab Invest 64 6 1991 819 825
33. V.M. Elner, W. Scales, S.G. Elner, J. Danforth, S.L. Kunkel, and R.M. Strieter Interleukin-6 (IL-6) gene expression and secretion by cytokine-stimulated human retinal pigment epithelial cells Exp Eye Res 54 3 1992 361 368
34. C.N. Nagineni, B. Detrick, and J.J. Hooks Synergistic effects of gamma interferon on inflammatory mediators that induce interleukin-6 gene expression and secretion by human retinal pigment epithelial cells Clin Diagn Lab Immunol 1 5 1994 569 577
35. A.O. Edwards, R. Ritter 3rd, K.J. Abel, A. Manning, C. Panhuysen, and L.A. Farrer Complement factor H polymorphism and age-related macular degeneration Science 308 5720 2005 421 424
36. G.S. Hageman, D.H. Anderson, and L.V. Johnson A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc Natl Acad Sci U S A 102 20 2005 7227 7232
37. J.L. Haines, M.A. Hauser, and S. Schmidt Complement factor H variant increases the risk of age-related macular degeneration Science 308 5720 2005 419 421
38. R.J. Klein, C. Zeiss, and E.Y. Chew Complement factor H polymorphism in age-related macular degeneration Science 308 5720 2005 385 389
39. R.R. Priya, E.Y. Chew, and A. Swaroop Genetic studies of age-related macular degeneration: lessons, challenges, and opportunities for disease management Ophthalmology 119 12 2012 2526 2536
40. D.T. Bradley, P.F. Zipfel, and A.E. Hughes Complement in age-related macular degeneration: a focus on function Eye 25 6 2011 683 693
41. D.H. Anderson, M.J. Radeke, and N.B. Gallo The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited Prog Retina Eye Res 29 2 2010 95 112
42. R.F. Mullins, A.D. Dewald, L.M. Streb, K. Wang, M.H. Kuehn, and E.M. Stone Elevated membrane attack complex in human choroid with high risk complement factor H genotypes Exp Eye Res 93 4 2011 565 567
43. M.M. Markiewski, and J.D. Lambris The role of complement in inflammatory diseases from behind the scenes into the spotlight Am J Pathol 171 3 2007 715 727
44. T. Takabayashi, E. Vannier, and B.D. Clark A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis J Immunol 156 9 1996 3455 3460
45. T. Takabayashi, E. Vannier, J.F. Burke, R.G. Tompkins, J.A. Gelfand, and B.D. Clark Both C3a and C3a(desArg) regulate interleukin-6 synthesis in human peripheral blood mononuclear cells J Infect Dis 177 6 1998 1622 1628
46. N. Lauer, M. Mihlan, and A. Hartmann Complement regulation at necrotic cell lesions is impaired by the age-related macular degeneration-associated factor-H His402 risk variant J Immunol 187 8 2011 4374 4383
47. N. Shanmugam, J.L. Figarola, Y. Li, P.M. Swiderski, S. Rahbar, and R. Natarajan Proinflammatory effects of advanced lipoxidation end products in monocytes Diabetes 57 4 2008 879 888
48. S.P. Mooijaart, K.M. Koeijvoets, E.J. Sijbrands, M.R. Daha, and R.G. Westendorp Complement factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large Exp Gerontol 42 11 2007 1116 1122
49. F.M. Mo, A.D. Proia, W.H. Johnson, D. Cyr, and K. Lashkari Interferon gamma-inducible protein-10 (IP-10) and eotaxin as biomarkers in age-related macular degeneration Invest Ophthalmol Vis Sci 51 8 2010 4226 4236
50. R. van Leeuwen, C.C. Klaver, J.R. Vingerling, A. Hofman, and P.T. de Jong The risk and natural course of age-related maculopathy: follow-up at 6 1/2 years in the Rotterdam study Arch Ophthalmol 121 4 2003 519 526
51. M.D. Davis, R.E. Gangnon, and L.Y. Lee The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS report no. 17 Arch Ophthalmol 123 11 2005 1484 1498