CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

EMBO Molecular Medicine

Volumn 5, Issue 11, 2013, Pages 1775-1793

  Sennlaub, Florian ^a,b,c,d   Auvynet, Constance ^a,b,e   Calippe, Bertrand ^a,b,c   Lavalette, Sophie ^a,b,c   Poupel, Lucie ^b,e   Hu, Shulong J ^a,b,c   Dominguez, Elisa ^a,b,c   Camelo, Serge ^a,b,c   Levy, Olivier ^a,b,c   Guyon, Elodie ^a,b,e   Saederup, Noah ^f,g   Charo, Israel F ^f,g   Rooijen, Nico Van ^h   Nandrot, Emeline ^a,b,c   Bourges, Jean Louis ^b,d,i,j   Behar Cohen, Francine ^b,d,i,j   Sahel, José Alain ^a,b,c   Guillonneau, Xavier ^a,b,c   Raoul, William ^a,b,c   Combadiere, Christophe ^b,e,k  

^a INSTITUT DE LA VISION   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c CENTRE HOSPITALIER NATIONAL D OPHTALMOLOGIE DES QUINZE VINGTS   (France)

^d HÔTEL DIEU   (France)

^e INSERM   (France)

^f GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h VU UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁱ CENTRE DE RECHERCHE DES CORDELIERS   (France)

^j UNIVERSITÉ PARIS DESCARTES   (France)

^k PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

more..

Author keywords

Age related macular disease; Chemokines; Monocyte; Neurodegeneration; Neuroinflammation

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; MONOCYTE CHEMOTACTIC PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; GENE DELETION; IN VIVO STUDY; MICROGLIA; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA; RETINA MACULA AGE RELATED DEGENERATION;

AGE-RELATED MACULAR DISEASE; CHEMOKINES; MONOCYTE; NEURODEGENERATION; NEUROINFLAMMATION;

ANIMALS; CHEMOKINE CCL2; FEMALE; HUMANS; INFLAMMATION; MACULAR DEGENERATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; NEUTROPHIL INFILTRATION; PHOTORECEPTOR CELLS, VERTEBRATE; RECEPTORS, CCR2; RECEPTORS, CHEMOKINE;

EID: 84887096324     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201302692     Document Type: Article

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