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Volumn 35, Issue 6, 2015, Pages 1195-1219

A Dilemma in the Glycosaminoglycan-Based Therapy: Synthetic or Naturally Unique Molecules?

Author keywords

Carbohydrate based drugs; Chemical synthesis, drug development; Enzymatic synthesis; Glycosaminoglycans; Oligosaccharide synthesis

Indexed keywords

GLYCOSAMINOGLYCAN; GLYCOSAMINOGLYCAN POLYSULFATE; OLIGOSACCHARIDE;

EID: 84943581541     PISSN: 01986325     EISSN: 10981128     Source Type: Journal    
DOI: 10.1002/med.21356     Document Type: Article
Times cited : (37)

References (128)
  • 1
    • 0033635310 scopus 로고    scopus 로고
    • Heparin and heparan sulfate: Biosynthesis, structure and function
    • Sasisekharan R, Venkataraman, G. Heparin and heparan sulfate: Biosynthesis, structure and function. Curr Opin Chem Biol 2000;4:626-631.
    • (2000) Curr Opin Chem Biol , vol.4 , pp. 626-631
    • Sasisekharan, R.1    Venkataraman, G.2
  • 2
    • 0035984272 scopus 로고    scopus 로고
    • Heparin and heparan sulfate: Structure and function
    • Rabestein DL. Heparin and heparan sulfate: Structure and function. Nat Prod Rep 2002;19:312-331.
    • (2002) Nat Prod Rep , vol.19 , pp. 312-331
    • Rabestein, D.L.1
  • 4
    • 0033785674 scopus 로고    scopus 로고
    • Keratan sulfate: Structure, biosynthesis, and function
    • Funderburgh JL. Keratan sulfate: Structure, biosynthesis, and function. Glycobiology 2000;10:951-958.
    • (2000) Glycobiology , vol.10 , pp. 951-958
    • Funderburgh, J.L.1
  • 5
    • 84907486331 scopus 로고    scopus 로고
    • Keratan sulfate: An up-to-date review
    • Pomin, VH. Keratan sulfate: An up-to-date review. Int J Biol Macromol 2015;72:282-289.
    • (2015) Int J Biol Macromol , vol.72 , pp. 282-289
    • Pomin, V.H.1
  • 6
    • 34447121482 scopus 로고    scopus 로고
    • Hyaluronan
    • Almond A. Hyaluronan. Cell Mol Life Sci 2007;64:1591-1596.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 1591-1596
    • Almond, A.1
  • 7
    • 56649100319 scopus 로고    scopus 로고
    • The structure of glycosaminoglycans and their interactions with proteins
    • Gandhi NS, Mancera RL. The structure of glycosaminoglycans and their interactions with proteins. Chem Biol Drug Des 2008;72:455-482.
    • (2008) Chem Biol Drug Des , vol.72 , pp. 455-482
    • Gandhi, N.S.1    Mancera, R.L.2
  • 8
    • 33745040961 scopus 로고    scopus 로고
    • Therapeutic applications of glycosaminoglycans
    • Volpi N. Therapeutic applications of glycosaminoglycans. Curr Med Chem 2006;13:1799-17810.
    • (2006) Curr Med Chem , vol.13 , pp. 1799-17810
    • Volpi, N.1
  • 9
    • 0035912864 scopus 로고    scopus 로고
    • Guide to anticoagulant therapy: Heparin: A statement for healthcare professionals from the American Heart Association
    • Hirsh J, Anand SS, Halperin JL, Fuster V. Guide to anticoagulant therapy: Heparin: A statement for healthcare professionals from the American Heart Association. Circulation 2001;103:2994-3018.
    • (2001) Circulation , vol.103 , pp. 2994-3018
    • Hirsh, J.1    Anand, S.S.2    Halperin, J.L.3    Fuster, V.4
  • 10
    • 4544363732 scopus 로고    scopus 로고
    • Treatment of venous thromboembolism. Initial treatment of venous thromboembolism
    • McRae SJ, Ginsberg JS. Treatment of venous thromboembolism. Initial treatment of venous thromboembolism. Circulation 2004;110:I-3-I-9.
    • (2004) Circulation , vol.110 , pp. I3-I9
    • McRae, S.J.1    Ginsberg, J.S.2
  • 11
    • 84864435639 scopus 로고    scopus 로고
    • Residual keratan sulfate in chondroitin sulfate formulations for oral administration
    • Pomin VH, Piquet AA, Pereira MS, Mourão PA. Residual keratan sulfate in chondroitin sulfate formulations for oral administration. Carbohydr Polym 2012;90:839-846.
    • (2012) Carbohydr Polym , vol.90 , pp. 839-846
    • Pomin, V.H.1    Piquet, A.A.2    Pereira, M.S.3    Mourão, P.A.4
  • 12
    • 77953684080 scopus 로고    scopus 로고
    • Proteoglycans and sulfated glycosaminoglycans
    • In: Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME, Eds., 2nd edition. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. Chapter 16
    • Esko JD, Kimata K, Lindahl U. Proteoglycans and sulfated glycosaminoglycans. In: Varki A, Cummings RD, Esko JD, Freeze HH, Stanley P, Bertozzi CR, Hart GW, Etzler ME, Eds. Essentials of Glycobiology, 2nd edition. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 2009. Chapter 16. Available from http://www.ncbi.nlm.nih.gov/books/NBK1900/
    • (2009) Essentials of Glycobiology
    • Esko, J.D.1    Kimata, K.2    Lindahl, U.3
  • 13
    • 79953067209 scopus 로고    scopus 로고
    • Hyaluronic acid hydrogels for biomedical applications
    • Burdick JA, Prestwich GD. Hyaluronic acid hydrogels for biomedical applications. Adv Mater 2011;23:H41-H56.
    • (2011) Adv Mater , vol.23 , pp. H41-H56
    • Burdick, J.A.1    Prestwich, G.D.2
  • 14
    • 84891782055 scopus 로고    scopus 로고
    • NMR chemical shifts in structural biology of glycosaminoglycans
    • Pomin VH. NMR chemical shifts in structural biology of glycosaminoglycans. Anal Chem 2014;86:65-94.
    • (2014) Anal Chem , vol.86 , pp. 65-94
    • Pomin, V.H.1
  • 15
    • 0032742808 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: A clinicopathologic genesis
    • Warkentin TE. Heparin-induced thrombocytopenia: A clinicopathologic genesis. Thromb Haemost 1999;82:439-447.
    • (1999) Thromb Haemost , vol.82 , pp. 439-447
    • Warkentin, T.E.1
  • 16
    • 0032723867 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Molecular pathogenesis
    • Visentin GP. Heparin-induced thrombocytopenia: Molecular pathogenesis. Thromb Haemost 1999;82:448-156.
    • (1999) Thromb Haemost , vol.82 , pp. 156-448
    • Visentin, G.P.1
  • 17
    • 0019076312 scopus 로고
    • Bleeding associated with antithrombotic therapy
    • Kelton, JG. Hirsh J. Bleeding associated with antithrombotic therapy. Semin Hematol 1980;17:259-379.
    • (1980) Semin Hematol , vol.17 , pp. 259-379
    • Kelton, J.G.1    Hirsh, J.2
  • 18
    • 0022485054 scopus 로고
    • Efficacy and safety of two regimens of low molecular weight heparin fragment Fragmin in preventing post-operative venous thromboembolism
    • Kakkar VV, Kakkar S, Sanderson RM, Peers CE. Efficacy and safety of two regimens of low molecular weight heparin fragment Fragmin in preventing post-operative venous thromboembolism. Haemostasis 1986;16:19-24.
    • (1986) Haemostasis , vol.16 , pp. 19-24
    • Kakkar, V.V.1    Kakkar, S.2    Sanderson, R.M.3    Peers, C.E.4
  • 19
    • 0024418642 scopus 로고
    • Clinical experience with antithrombin III concentrate in treatment of congenital and acquired deficiency of antithrombin. The Antithrombin III Study Group
    • Schwartz RS, Bauer KA, Rosenberg RD, Kavanaugh EJ, Davies DC, Bogdanoff DA. Clinical experience with antithrombin III concentrate in treatment of congenital and acquired deficiency of antithrombin. The Antithrombin III Study Group. Am J Med 1989;87:53S-60S.
    • (1989) Am J Med , vol.87 , pp. 53S-60S
    • Schwartz, R.S.1    Bauer, K.A.2    Rosenberg, R.D.3    Kavanaugh, E.J.4    Davies, D.C.5    Bogdanoff, D.A.6
  • 20
    • 0032712157 scopus 로고    scopus 로고
    • Inhibition of the generation of thrombin and factor Xa by a fucoidan from the brown seaweed Ecklonia kurome
    • Nishino T, Fukuda A, Nagumo T, Fujihara M, Kaji E. Inhibition of the generation of thrombin and factor Xa by a fucoidan from the brown seaweed Ecklonia kurome. Thromb Res 1999;96:37-49.
    • (1999) Thromb Res , vol.96 , pp. 37-49
    • Nishino, T.1    Fukuda, A.2    Nagumo, T.3    Fujihara, M.4    Kaji, E.5
  • 21
    • 0035877794 scopus 로고    scopus 로고
    • Molecular basis for the susceptibility of fibrin-bound thrombin to inactivation by heparin cofactor II in the presence of dermatan sulfate but not heparin
    • Liaw PCY, Becker DJ, Stafford AR, Fredenburgh JC, Weitz JI. Molecular basis for the susceptibility of fibrin-bound thrombin to inactivation by heparin cofactor II in the presence of dermatan sulfate but not heparin. J Biol Chem 2001; 276:20959-20965.
    • (2001) J Biol Chem , vol.276 , pp. 20959-20965
    • Liaw, P.C.Y.1    Becker, D.J.2    Stafford, A.R.3    Fredenburgh, J.C.4    Weitz, J.I.5
  • 22
    • 84910652229 scopus 로고    scopus 로고
    • Structural and functional analyses of bovine and porcine intestinal heparins confirm they are different drugs
    • Santos GR, Tovar AM, Capillé NV, Pereira MS, Pomin VH, Mourão PA. Structural and functional analyses of bovine and porcine intestinal heparins confirm they are different drugs. Drug Discov Today 2014;19:1801-1807.
    • (2014) Drug Discov Today , vol.19 , pp. 1801-1807
    • Santos, G.R.1    Tovar, A.M.2    Capillé, N.V.3    Pereira, M.S.4    Pomin, V.H.5    Mourão, P.A.6
  • 23
    • 1842479365 scopus 로고    scopus 로고
    • College of American Pathologists. Heparin monitoring and patient safety: a College of American Pathologists Q-Probes study of 3431 patients at 140 institutions
    • Valenstein PN, Walsh MK, Meier F, College of American Pathologists. Heparin monitoring and patient safety: a College of American Pathologists Q-Probes study of 3431 patients at 140 institutions. Arch Pathol Lab Med 2004;128:397-402.
    • (2004) Arch Pathol Lab Med , vol.128 , pp. 397-402
    • Valenstein, P.N.1    Walsh, M.K.2    Meier, F.3
  • 26
    • 79251605463 scopus 로고    scopus 로고
    • New developments in the characterization of heparin and its impurities
    • Larive CK. New developments in the characterization of heparin and its impurities. Anal Bioanal Chem 2011;399:525-526.
    • (2011) Anal Bioanal Chem , vol.399 , pp. 525-526
    • Larive, C.K.1
  • 27
    • 61449171129 scopus 로고    scopus 로고
    • Lessons learned from the contamination of heparin
    • Liu H, Zhang Z, Linhardt RJ. Lessons learned from the contamination of heparin. Nat Prod Rep 2012;26:313-321.
    • (2012) Nat Prod Rep , vol.26 , pp. 313-321
    • Liu, H.1    Zhang, Z.2    Linhardt, R.J.3
  • 28
    • 44949233239 scopus 로고    scopus 로고
    • The FDA and safety-Beyond the heparin crisis
    • Laurencin CT, Nair L. The FDA and safety-Beyond the heparin crisis. Nat Biotechnol 2008;26:621-623.
    • (2008) Nat Biotechnol , vol.26 , pp. 621-623
    • Laurencin, C.T.1    Nair, L.2
  • 29
    • 60549089837 scopus 로고    scopus 로고
    • Tainted heparin crisis tested FDA's investigative skills
    • Lavine G. Tainted heparin crisis tested FDA's investigative skills. Am J Health Syst Pharm 2009;66:210-211.
    • (2009) Am J Health Syst Pharm , vol.66 , pp. 210-211
    • Lavine, G.1
  • 30
    • 70449572936 scopus 로고    scopus 로고
    • From crisis to opportunity: A perspective on the heparin crisis
    • Sasisekharan R, Shriver Z. From crisis to opportunity: A perspective on the heparin crisis. Thromb Haemost 2009;102;854-858.
    • (2009) Thromb Haemost , vol.102 , pp. 854-858
    • Sasisekharan, R.1    Shriver, Z.2
  • 31
    • 84881394944 scopus 로고    scopus 로고
    • Heparin crisis 2008: A tipping point for increased FDA enforcement in the pharma sector?
    • Rosania L. Heparin crisis 2008: A tipping point for increased FDA enforcement in the pharma sector? Food Drug Law J 2010;65:489-501.
    • (2010) Food Drug Law J , vol.65 , pp. 489-501
    • Rosania, L.1
  • 32
    • 19944404265 scopus 로고    scopus 로고
    • Carbohydrates as the next frontier in pharmaceutical research
    • Werz DB, Seeberger PH. Carbohydrates as the next frontier in pharmaceutical research. Chem Eur J 2005;11:3194-3206.
    • (2005) Chem Eur J , vol.11 , pp. 3194-3206
    • Werz, D.B.1    Seeberger, P.H.2
  • 33
    • 26044440288 scopus 로고    scopus 로고
    • Automated synthesis of oligosaccharides as a basis for drug discovery
    • Seeberger PH, Werz DB. Automated synthesis of oligosaccharides as a basis for drug discovery. Nat Rev Drug Discov 2005;4:751-763.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 751-763
    • Seeberger, P.H.1    Werz, D.B.2
  • 34
    • 70350441377 scopus 로고    scopus 로고
    • Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research
    • Boltje TJ, Buskas T, Boons GJ. Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research. Nat Chem 2009;1:611-622.
    • (2009) Nat Chem , vol.1 , pp. 611-622
    • Boltje, T.J.1    Buskas, T.2    Boons, G.J.3
  • 35
    • 84870874385 scopus 로고    scopus 로고
    • Acylsulfonamide safety-catch linker: Promise and limitations for solid-phase oligosaccharide synthesis
    • Yin J, Eller S, Collot M, Seeberger PH. Acylsulfonamide safety-catch linker: Promise and limitations for solid-phase oligosaccharide synthesis. Beilstein J Org Chem 2012;8:2067-2071.
    • (2012) Beilstein J Org Chem , vol.8 , pp. 2067-2071
    • Yin, J.1    Eller, S.2    Collot, M.3    Seeberger, P.H.4
  • 36
    • 84902438188 scopus 로고    scopus 로고
    • A multifunctional anomeric linker for the chemoenzymatic synthesis of complex oligosaccharides
    • Prudden AR, Chinoy ZS, Wolfert MA, Boons GJ. A multifunctional anomeric linker for the chemoenzymatic synthesis of complex oligosaccharides. Chem Commun 2014;50:7132-7135.
    • (2014) Chem Commun , vol.50 , pp. 7132-7135
    • Prudden, A.R.1    Chinoy, Z.S.2    Wolfert, M.A.3    Boons, G.J.4
  • 37
    • 79960566715 scopus 로고    scopus 로고
    • Enzymes in the synthesis of glycoconjugates
    • Schmaltz RM, Hanson SR, Wong CH. Enzymes in the synthesis of glycoconjugates. Chem Rev 2011;111:4259-4307.
    • (2011) Chem Rev , vol.111 , pp. 4259-4307
    • Schmaltz, R.M.1    Hanson, S.R.2    Wong, C.H.3
  • 38
    • 0141426753 scopus 로고    scopus 로고
    • Recent chemical and enzymatic approaches to the synthesis of glycosaminoglycans oligosaccharides
    • Karst NA, Linhardt RJ. Recent chemical and enzymatic approaches to the synthesis of glycosaminoglycans oligosaccharides. Curr Med Chem 2003;10:1993-2031.
    • (2003) Curr Med Chem , vol.10 , pp. 1993-2031
    • Karst, N.A.1    Linhardt, R.J.2
  • 39
    • 36849042592 scopus 로고    scopus 로고
    • Chapter 15-Enzymatic synthesis of glycosaminoglycans: Improving on nature
    • Avci FY, DeAngelis PL, Liu J, Linhardt RJ. Chapter 15-Enzymatic synthesis of glycosaminoglycans: Improving on nature. Front Mod Carb Chem 2007;960:253-284.
    • (2007) Front Mod Carb Chem , vol.960 , pp. 253-284
    • Avci, F.Y.1    DeAngelis, P.L.2    Liu, J.3    Linhardt, R.J.4
  • 40
    • 84880038115 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis of glycosaminoglycans: Re-creating, re-modeling and re-designing naturés longest or most complex carbohydrate chains
    • DeAngelis PL, Liu J, Linhardt RJ. Chemoenzymatic synthesis of glycosaminoglycans: Re-creating, re-modeling and re-designing naturés longest or most complex carbohydrate chains. Glycobiology 2013;23:764-777.
    • (2013) Glycobiology , vol.23 , pp. 764-777
    • DeAngelis, P.L.1    Liu, J.2    Linhardt, R.J.3
  • 41
    • 84910051456 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis of heparan sulfate and heparin
    • Liu J, Linhardt RJ. Chemoenzymatic synthesis of heparan sulfate and heparin. Nat Prod Rep 2014;31:129-157.
    • (2014) Nat Prod Rep , vol.31 , pp. 129-157
    • Liu, J.1    Linhardt, R.J.2
  • 42
    • 0034994242 scopus 로고    scopus 로고
    • Towards a modular approach for heparin synthesis
    • Haller M, Boons GJ. Towards a modular approach for heparin synthesis. J Chem Soc Perkin Trans 1 2001; 814-822.
    • (2001) J Chem Soc Perkin Trans 1 , pp. 814-822
    • Haller, M.1    Boons, G.J.2
  • 43
    • 0036314235 scopus 로고    scopus 로고
    • Selectively protected disaccharide building blocks for modular synthesis of heparin fragments
    • Haller MF, Boons GJ. Selectively protected disaccharide building blocks for modular synthesis of heparin fragments. Eur J Org Chem 2002;2002:2033-2038.
    • (2002) Eur J Org Chem , vol.2002 , pp. 2033-2038
    • Haller, M.F.1    Boons, G.J.2
  • 44
    • 0141789698 scopus 로고    scopus 로고
    • Synthesis of iduronic acid building blocks for the modular assembly of glycosaminoglycans
    • Lohman GJS, Hunt DK, Högermeier JA, Seeberger PH. Synthesis of iduronic acid building blocks for the modular assembly of glycosaminoglycans. J Org Chem 2003;68:7559-7561.
    • (2003) J Org Chem , vol.68 , pp. 7559-7561
    • Lohman, G.J.S.1    Hunt, D.K.2    Högermeier, J.A.3    Seeberger, P.H.4
  • 46
    • 2942536229 scopus 로고    scopus 로고
    • A stereochemical surprise at the late stage of the synthesis of fully N-differentiated heparin oligosaccharides containing amino, acetamino, and N-sulfonate groups
    • Lohman GJS, Seeberger PH. A stereochemical surprise at the late stage of the synthesis of fully N-differentiated heparin oligosaccharides containing amino, acetamino, and N-sulfonate groups. J Org Chem 2004;69:4081-4093.
    • (2004) J Org Chem , vol.69 , pp. 4081-4093
    • Lohman, G.J.S.1    Seeberger, P.H.2
  • 47
    • 22644444072 scopus 로고    scopus 로고
    • Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans
    • Noti C, Seeberger PH. Chemical approaches to define the structure-activity relationship of heparin-like glycosaminoglycans. Chem Biol 2005;12:731-756.
    • (2005) Chem Biol , vol.12 , pp. 731-756
    • Noti, C.1    Seeberger, P.H.2
  • 49
    • 33644946682 scopus 로고    scopus 로고
    • Microarrays of synthetic heparin oligosaccharides
    • de Paz JL, Noti C, Seeberger PH. Microarrays of synthetic heparin oligosaccharides. J Am Chem Soc 2006;128:2766-2767.
    • (2006) J Am Chem Soc , vol.128 , pp. 2766-2767
    • de Paz, J.L.1    Noti, C.2    Seeberger, P.H.3
  • 50
    • 33845218763 scopus 로고    scopus 로고
    • Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions
    • Noti C, dePaz JL, Polito L, Seeberger PH. Preparation and use of microarrays containing synthetic heparin oligosaccharides for the rapid analysis of heparin-protein interactions. Chem Eur J 2006;12:8664-8666.
    • (2006) Chem Eur J , vol.12 , pp. 8664-8666
    • Noti, C.1    de Paz, J.L.2    Polito, L.3    Seeberger, P.H.4
  • 51
    • 34547948541 scopus 로고    scopus 로고
    • Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers
    • dePaz JL, Noti C, Böhm F, Werner S, Seeberger PH. Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers. Chem Biol 2007;14:879-887.
    • (2007) Chem Biol , vol.14 , pp. 879-887
    • de Paz, J.L.1    Noti, C.2    Böhm, F.3    Werner, S.4    Seeberger, P.H.5
  • 54
    • 65349085618 scopus 로고    scopus 로고
    • Design of biologically active heparan sulfate and heparin using an enzyme-based approach
    • Peterson S, Frick A, Liu J. Design of biologically active heparan sulfate and heparin using an enzyme-based approach. Nat Prod Rep 2009;26:610-627.
    • (2009) Nat Prod Rep , vol.26 , pp. 610-627
    • Peterson, S.1    Frick, A.2    Liu, J.3
  • 55
    • 84865235998 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis of heparin oligosaccharides with both anti-Xa and anti-IIa activities
    • Xu Y, Pempe EH, Liu J. Chemoenzymatic synthesis of heparin oligosaccharides with both anti-Xa and anti-IIa activities. J Biol Chem 2012;287:29054-29061.
    • (2012) J Biol Chem , vol.287 , pp. 29054-29061
    • Xu, Y.1    Pempe, E.H.2    Liu, J.3
  • 56
    • 84876084809 scopus 로고    scopus 로고
    • Heparosan-derived heparan sulfate/heparin-like compounds: one kind of potential therapeutic agents
    • Li P, Sheng J, Liu Y, Li J, Liu J, Wang F. Heparosan-derived heparan sulfate/heparin-like compounds: one kind of potential therapeutic agents. Med Res Rev 2013;3:665-692.
    • (2013) Med Res Rev , vol.3 , pp. 665-692
    • Li, P.1    Sheng, J.2    Liu, Y.3    Li, J.4    Liu, J.5    Wang, F.6
  • 58
    • 0347916941 scopus 로고    scopus 로고
    • New set of orthogonal protecting groups for the modular synthesis of heparan sulfate fragments
    • Prabhu A, Venot A, Boons GJ. New set of orthogonal protecting groups for the modular synthesis of heparan sulfate fragments. Org Lett 2003;5:4975-4978.
    • (2003) Org Lett , vol.5 , pp. 4975-4978
    • Prabhu, A.1    Venot, A.2    Boons, G.J.3
  • 61
    • 84855646812 scopus 로고    scopus 로고
    • A synthetic heparan sulfate oligosaccharide library reveals the novel enzymatic action of D-glucosaminyl 3-O-sulfotransferase-3a
    • Nguyen TKN, Arungundram S, Tran VM, Raman K, Al-Mafraji K, Venot A, Boons GJ, Kuberan B. A synthetic heparan sulfate oligosaccharide library reveals the novel enzymatic action of D-glucosaminyl 3-O-sulfotransferase-3a. Mol Biosyst 2012;8:609-614.
    • (2012) Mol Biosyst , vol.8 , pp. 609-614
    • Nguyen, T.K.N.1    Arungundram, S.2    Tran, V.M.3    Raman, K.4    Al-Mafraji, K.5    Venot, A.6    Boons, G.J.7    Kuberan, B.8
  • 62
    • 84870538031 scopus 로고    scopus 로고
    • Electron detachment dissociation of synthetic heparan sulfate glycosaminoglycans tetrasaccharides varying in degree of sulfation and hexuronic acid stereochemistry
    • Leach III FE, Arungundram S, Al-Mafraji K, Venot A, Boons GJ, Amster IJ. Electron detachment dissociation of synthetic heparan sulfate glycosaminoglycans tetrasaccharides varying in degree of sulfation and hexuronic acid stereochemistry. Int J Mass Spectrom 2012;330-332:152-159.
    • (2012) Int J Mass Spectrom , vol.330-332 , pp. 152-159
    • Leach, F.E.1    Arungundram, S.2    Al-Mafraji, K.3    Venot, A.4    Boons, G.J.5    Amster, I.J.6
  • 63
    • 84872535620 scopus 로고    scopus 로고
    • Fluorous supported modular synthesis of heparan sulfate oligosaccharides
    • Zong C, Venot A, Dhamale O, Boons GJ. Fluorous supported modular synthesis of heparan sulfate oligosaccharides. Org Lett 15:342-345.
    • Org Lett , vol.15 , pp. 342-345
    • Zong, C.1    Venot, A.2    Dhamale, O.3    Boons, G.J.4
  • 64
    • 84903718332 scopus 로고    scopus 로고
    • Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides
    • Hsieh PH, Xu Y, Keire DA, Liu J. Chemoenzymatic synthesis and structural characterization of 2-O-sulfated glucuronic acid-containing heparan sulfate hexasaccharides. Glycobiology 2014;24:681-692.
    • (2014) Glycobiology , vol.24 , pp. 681-692
    • Hsieh, P.H.1    Xu, Y.2    Keire, D.A.3    Liu, J.4
  • 65
    • 84897681556 scopus 로고    scopus 로고
    • New glucuronic acid donors for the modular synthesis of heparan sulfate oligosaccharides
    • Dhamale OP, Zong C, Al-Mafraji K, Boons GJ. New glucuronic acid donors for the modular synthesis of heparan sulfate oligosaccharides. Org Biomol Chem 2014;12:2087-2098.
    • (2014) Org Biomol Chem , vol.12 , pp. 2087-2098
    • Dhamale, O.P.1    Zong, C.2    Al-Mafraji, K.3    Boons, G.J.4
  • 67
    • 84878072339 scopus 로고    scopus 로고
    • Automated solid-phase synthesis of chondroitin sulfate glycosaminoglycans
    • Eller S, Collot M, Yin J, Hahm HS, Seeberger PH. Automated solid-phase synthesis of chondroitin sulfate glycosaminoglycans. Angew Chem Int Ed 2013;52:5858-5861.
    • (2013) Angew Chem Int Ed , vol.52 , pp. 5858-5861
    • Eller, S.1    Collot, M.2    Yin, J.3    Hahm, H.S.4    Seeberger, P.H.5
  • 68
    • 84921714540 scopus 로고    scopus 로고
    • Automated synthesis of chondroitin sulfate oligosaccharides
    • Liang CF, Hahm HS, Seeberger PH. Automated synthesis of chondroitin sulfate oligosaccharides. Methods Mol Biol 2015;1229:3-10.
    • (2015) Methods Mol Biol , vol.1229 , pp. 3-10
    • Liang, C.F.1    Hahm, H.S.2    Seeberger, P.H.3
  • 70
    • 84904862825 scopus 로고    scopus 로고
    • Isolation and characterization of hyaluronic acid from marine organisms
    • Giji S, Arumugam M. Isolation and characterization of hyaluronic acid from marine organisms. Adv Food Nutr Res 2014;72:61-77.
    • (2014) Adv Food Nutr Res , vol.72 , pp. 61-77
    • Giji, S.1    Arumugam, M.2
  • 71
    • 84886508145 scopus 로고    scopus 로고
    • Isolation, characterization and antioxidant activity of hyaluronic acid from marine bivalve mollusc Amussium pleuronectus (Linnaeus, 1758)
    • Kanchana S, Arumugam M, Giji S, Balasubramanian T. Isolation, characterization and antioxidant activity of hyaluronic acid from marine bivalve mollusc Amussium pleuronectus (Linnaeus, 1758). Bioactive Carbohydr Diet Fibre 2013;2:1-7.
    • (2013) Bioactive Carbohydr Diet Fib , vol.2 , pp. 1-7
    • Kanchana, S.1    Arumugam, M.2    Giji, S.3    Balasubramanian, T.4
  • 72
    • 84875792414 scopus 로고    scopus 로고
    • Chondroitin sulfate, hyaluronic acid and chitin/chitosan production using marine waste sources: Characteristics, applications and eco-friendly processes: A review
    • Vázquez JA, Rodríguez-Amado I, Montemayor MI, Fraguas J, González Mdel P, Murado MA. Chondroitin sulfate, hyaluronic acid and chitin/chitosan production using marine waste sources: Characteristics, applications and eco-friendly processes: A review. Mar Drugs 2013;11:747-774.
    • (2013) Mar Drugs , vol.11 , pp. 747-774
    • Vázquez, J.A.1    Rodríguez-Amado, I.2    Montemayor, M.I.3    Fraguas, J.4    González Mdel, P.5    Murado, M.A.6
  • 73
    • 0021762049 scopus 로고
    • Isolation and characterization of an asparagine-linked keratan sulfate from the skin of a marine teleost, Scomber japonicus
    • Ito M, Kitamikado M, Yamagata T. Isolation and characterization of an asparagine-linked keratan sulfate from the skin of a marine teleost, Scomber japonicus. Biochim Biophys Acta 1984;797:221-230.
    • (1984) Biochim Biophys Acta , vol.797 , pp. 221-230
    • Ito, M.1    Kitamikado, M.2    Yamagata, T.3
  • 74
    • 77951250841 scopus 로고    scopus 로고
    • Unique extracellular matrix heparan sulfate from the bivalve Nodipecten nodosus (Linnaeus, 1758) safely inhibits arterial thrombosis after photochemically induced endothelial lesion
    • Gomes AM, Kozlowski EO, Pomin VH, de Barros CM, Zaganeli JL, Pavão MS. Unique extracellular matrix heparan sulfate from the bivalve Nodipecten nodosus (Linnaeus, 1758) safely inhibits arterial thrombosis after photochemically induced endothelial lesion. J Biol Chem 2010;285:7312-7323.
    • (2010) J Biol Chem , vol.285 , pp. 7312-7323
    • Gomes, A.M.1    Kozlowski, E.O.2    Pomin, V.H.3    de Barros, C.M.4    Zaganeli, J.L.5    Pavão, M.S.6
  • 77
    • 1342343931 scopus 로고    scopus 로고
    • Acharan sulfate, the new glycosaminoglycan from Achatina fulica Bowdich 1822. Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix
    • Vieira TC, Costa-Filho A, Salgado NC, Allodi S, Valente AP, Nasciutti LE, Silva LC. Acharan sulfate, the new glycosaminoglycan from Achatina fulica Bowdich 1822. Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix. Eur J Biochem 2004;271:845-854.
    • (2004) Eur J Biochem , vol.271 , pp. 845-854
    • Vieira, T.C.1    Costa-Filho, A.2    Salgado, N.C.3    Allodi, S.4    Valente, A.P.5    Nasciutti, L.E.6    Silva, L.C.7
  • 78
    • 66949143365 scopus 로고    scopus 로고
    • Antiproliferative heparin (glycosaminoglycans) isolated from giant clam (Tridacna maxima) and green mussel (Perna viridis)
    • Arumugam M, Garg H, Ajithkumar T, Shanmugam A. Antiproliferative heparin (glycosaminoglycans) isolated from giant clam (Tridacna maxima) and green mussel (Perna viridis). Afr J Biotechnol 2009;8:2394-2396.
    • (2009) Afr J Biotechnol , vol.8 , pp. 2394-2396
    • Arumugam, M.1    Garg, H.2    Ajithkumar, T.3    Shanmugam, A.4
  • 79
    • 84941053916 scopus 로고    scopus 로고
    • Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment
    • Gomes AM, Kozlowski EO, Borsig L, Teixeira FC, Vlodavsky I, Pavão MS. Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment. Glycobiology 2015;25:386-393.
    • (2015) Glycobiology , vol.25 , pp. 386-393
    • Gomes, A.M.1    Kozlowski, E.O.2    Borsig, L.3    Teixeira, F.C.4    Vlodavsky, I.5    Pavão, M.S.6
  • 80
    • 84898074624 scopus 로고    scopus 로고
    • A heparin-like glycosaminoglycan from shrimp containing high levels of 3-O-sulfated D-glucosamine groups in an unusual trisaccharide sequence
    • Chavante SF, Brito AS, Lima M, Yates E, Nader H, Guerrini M, Torri G, Bisio A. A heparin-like glycosaminoglycan from shrimp containing high levels of 3-O-sulfated D-glucosamine groups in an unusual trisaccharide sequence. Carbohydr Res 2014;390:59-66.
    • (2014) Carbohydr Res , vol.390 , pp. 59-66
    • Chavante, S.F.1    Brito, A.S.2    Lima, M.3    Yates, E.4    Nader, H.5    Guerrini, M.6    Torri, G.7    Bisio, A.8
  • 81
    • 1842636864 scopus 로고    scopus 로고
    • Long duration of anticoagulant activity and protective effects of acharan sulfate in vivo
    • Li DW, Lee IS, Sim JS, Toida T, Linhardt RJ, Kim YS. Long duration of anticoagulant activity and protective effects of acharan sulfate in vivo. Thromb Res 2004;113:67-73.
    • (2004) Thromb Res , vol.113 , pp. 67-73
    • Li, D.W.1    Lee, I.S.2    Sim, J.S.3    Toida, T.4    Linhardt, R.J.5    Kim, Y.S.6
  • 84
    • 0037666120 scopus 로고    scopus 로고
    • Pharmacological activities of a new glycosaminoglycan, acharan sulfate isolated from the giant African snail Achatina fulica
    • Shim JY, Lee YS, Jung SH, Choi HS, Shin KH, Kim YS. Pharmacological activities of a new glycosaminoglycan, acharan sulfate isolated from the giant African snail Achatina fulica. Arch Pharm Res 2002;25:889-894.
    • (2002) Arch Pharm Res , vol.25 , pp. 889-894
    • Shim, J.Y.1    Lee, Y.S.2    Jung, S.H.3    Choi, H.S.4    Shin, K.H.5    Kim, Y.S.6
  • 87
    • 77954951116 scopus 로고    scopus 로고
    • Induction of nucleolin translocation by acharan sulfate in A549 human lung adenocarcinoma
    • Joo EJ, Yang H, Park Y, Park NY, Toida T, Linhardt RJ, Kim YS. Induction of nucleolin translocation by acharan sulfate in A549 human lung adenocarcinoma. J Cell Biochem 2010;110:1272-1278.
    • (2010) J Cell Biochem , vol.110 , pp. 1272-1278
    • Joo, E.J.1    Yang, H.2    Park, Y.3    Park, N.Y.4    Toida, T.5    Linhardt, R.J.6    Kim, Y.S.7
  • 88
    • 80054770002 scopus 로고    scopus 로고
    • Inhibition of Helicobacter pylori adhesion to Kato III cells by intact and low molecular weight acharan sulfate
    • Sim JS, Hahn BS, Im AR, Park Y, Shin JE, Bae EA, Kim DH, Kim YS. Inhibition of Helicobacter pylori adhesion to Kato III cells by intact and low molecular weight acharan sulfate. Glycoconj J 2011;28:411-418.
    • (2011) Glycoconj J , vol.28 , pp. 411-418
    • Sim, J.S.1    Hahn, B.S.2    Im, A.R.3    Park, Y.4    Shin, J.E.5    Bae, E.A.6    Kim, D.H.7    Kim, Y.S.8
  • 89
    • 84883830622 scopus 로고    scopus 로고
    • Wound healing and antibacterial activities of chondroitin sulfate- and acharan sulfate-reduced silver nanoparticles
    • Im AR, Kim JY, Kim HS, Cho S, Park Y, Kim YS. Wound healing and antibacterial activities of chondroitin sulfate- and acharan sulfate-reduced silver nanoparticles. Nanotechnology 2013;24:395102.
    • (2013) Nanotechnology , vol.24 , pp. 395102
    • Im, A.R.1    Kim, J.Y.2    Kim, H.S.3    Cho, S.4    Park, Y.5    Kim, Y.S.6
  • 90
    • 34547616504 scopus 로고    scopus 로고
    • Activation of professional antigen presenting cells by acharan sulfate isolated from giant African snail, Achatina fulica
    • Kim HS, Lee YH, Lee YR, Im SA, Lee JK, Kim YS, Sim JS, Choi HS, Lee CK. Activation of professional antigen presenting cells by acharan sulfate isolated from giant African snail, Achatina fulica. Arch Pharm Res 2007;30:866-870.
    • (2007) Arch Pharm Res , vol.30 , pp. 866-870
    • Kim, H.S.1    Lee, Y.H.2    Lee, Y.R.3    Im, S.A.4    Lee, J.K.5    Kim, Y.S.6    Sim, J.S.7    Choi, H.S.8    Lee, C.K.9
  • 91
    • 80155168926 scopus 로고    scopus 로고
    • Mining invertebrate natural products for future therapeutic treasure
    • Park Y. Mining invertebrate natural products for future therapeutic treasure. Nat Prod Commun 2011;6:1403-1408.
    • (2011) Nat Prod Commun , vol.6 , pp. 1403-1408
    • Park, Y.1
  • 92
    • 0024279639 scopus 로고
    • Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber
    • Vieira RP, Mourão PA, Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumber. J Biol Chem 1988;263:18176-18183.
    • (1988) J Biol Chem , vol.263 , pp. 18176-18183
    • Vieira, R.P.1    Mourão, P.A.2
  • 93
    • 0025895050 scopus 로고
    • Structure of a fucose-branched chondroitin sulfate from sea cucumber. Evidence for the presence of 3-O-sulfo-beta-D-glucuronosyl residues
    • Vieira RP, Mulloy B, Mourão PA. Structure of a fucose-branched chondroitin sulfate from sea cucumber. Evidence for the presence of 3-O-sulfo-beta-D-glucuronosyl residues. J Biol Chem 1991;266:13530-13536.
    • (1991) J Biol Chem , vol.266 , pp. 13530-13536
    • Vieira, R.P.1    Mulloy, B.2    Mourão, P.A.3
  • 94
    • 0029796369 scopus 로고    scopus 로고
    • Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant action
    • Mourão PA, Pereira MS, Pavão MS, Mulloy B, Tollefsen DM, Mowinckel MC, Abildgaard U. Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant action. J Biol Chem 1996;271:23973-23984.
    • (1996) J Biol Chem , vol.271 , pp. 23973-23984
    • Mourão, P.A.1    Pereira, M.S.2    Pavão, M.S.3    Mulloy, B.4    Tollefsen, D.M.5    Mowinckel, M.C.6    Abildgaard, U.7
  • 95
    • 70449581263 scopus 로고    scopus 로고
    • Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding. Practical and conceptual implications
    • Fonseca RJ, Santos GR, Mourão PA. Effects of polysaccharides enriched in 2, 4-disulfated fucose units on coagulation, thrombosis and bleeding. Practical and conceptual implications. Thromb Haemost 2009;102:829-836.
    • (2009) Thromb Haemost , vol.102 , pp. 829-836
    • Fonseca, R.J.1    Santos, G.R.2    Mourão, P.A.3
  • 96
    • 84892865069 scopus 로고    scopus 로고
    • Holothurian fucosylated chondroitin sulfate
    • Pomin, VH. Holothurian fucosylated chondroitin sulfate. Mar Drugs 2014;12:232-254.
    • (2014) Mar Drugs , vol.12 , pp. 232-254
    • Pomin, V.H.1
  • 97
    • 78349310561 scopus 로고    scopus 로고
    • Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers
    • Chen S, Xue C, Yin L, Tang Q, Yu G, Chai W. Comparison of structures and anticoagulant activities of fucosylated chondroitin sulfates from different sea cucumbers. Carbohydr Polym 2011;83:688-696.
    • (2011) Carbohydr Polym , vol.83 , pp. 688-696
    • Chen, S.1    Xue, C.2    Yin, L.3    Tang, Q.4    Yu, G.5    Chai, W.6
  • 98
    • 77952087454 scopus 로고    scopus 로고
    • Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharides
    • Fonseca RJ, Oliveira SN, Pomin VH, Mecawi AS, Araujo IG, Mourão PA. Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharides. Thromb Haemost 2010;103:994-1004.
    • (2010) Thromb Haemost , vol.103 , pp. 994-1004
    • Fonseca, R.J.1    Oliveira, S.N.2    Pomin, V.H.3    Mecawi, A.S.4    Araujo, I.G.5    Mourão, P.A.6
  • 99
    • 84920160745 scopus 로고    scopus 로고
    • Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase
    • Wu M, Wen D, Gao N, Xiao C, Yang L, Xu L, Lian W, Peng W, Jiang J, Zhao J. Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase. Eur J Med Chem 2015;92:257-269.
    • (2015) Eur J Med Chem , vol.92 , pp. 257-269
    • Wu, M.1    Wen, D.2    Gao, N.3    Xiao, C.4    Yang, L.5    Xu, L.6    Lian, W.7    Peng, W.8    Jiang, J.9    Zhao, J.10
  • 100
    • 0031831742 scopus 로고    scopus 로고
    • Antithrombotic activity of a fucosylated chondroitin sulphate from echinoderm: Sulphated fucose branches on the polysaccharide account for its antithrombotic action
    • Mourão PA, Guimarães B, Mulloy B, Thomas S, Gray E. Antithrombotic activity of a fucosylated chondroitin sulphate from echinoderm: Sulphated fucose branches on the polysaccharide account for its antithrombotic action. Br J Haematol 1998;101:647-652.
    • (1998) Br J Haematol , vol.101 , pp. 647-652
    • Mourão, P.A.1    Guimarães, B.2    Mulloy, B.3    Thomas, S.4    Gray, E.5
  • 101
    • 0033833568 scopus 로고    scopus 로고
    • Different antithrombotic mechanisms among glycosaminoglycans revealed with a new fucosylated chondroitin sulfate from an echinoderm
    • Pacheco RG, Vicente CP, Zancan P, Mourão PA. Different antithrombotic mechanisms among glycosaminoglycans revealed with a new fucosylated chondroitin sulfate from an echinoderm. Blood Coagul Fibrinol 2000;11:563-573.
    • (2000) Blood Coagul Fibrinol , vol.11 , pp. 563-573
    • Pacheco, R.G.1    Vicente, C.P.2    Zancan, P.3    Mourão, P.A.4
  • 102
    • 1642265920 scopus 로고    scopus 로고
    • Use of sulfated fucans as anticoagulant and antithrombotic agents: Future perspectives
    • Mourão PA. Use of sulfated fucans as anticoagulant and antithrombotic agents: Future perspectives. Curr Pharm Des 2004;10:967-981.
    • (2004) Curr Pharm Des , vol.10 , pp. 967-981
    • Mourão, P.A.1
  • 103
    • 2042546747 scopus 로고    scopus 로고
    • Venous and arterial thrombosis in rat models: Dissociation of the antithrombotic effects of glycosaminoglycans
    • Zancan P, Mourão PA. Venous and arterial thrombosis in rat models: Dissociation of the antithrombotic effects of glycosaminoglycans. Blood Coagul Fibrinol 2004;15:45-54.
    • (2004) Blood Coagul Fibrinol , vol.15 , pp. 45-54
    • Zancan, P.1    Mourão, P.A.2
  • 104
    • 33845361767 scopus 로고    scopus 로고
    • Fucosylated chondroitin sulfate as a new oral antithrombotic agent
    • Fonseca RJ, Mourão PA. Fucosylated chondroitin sulfate as a new oral antithrombotic agent. Thromb Haemost 2006;96:822-829.
    • (2006) Thromb Haemost , vol.96 , pp. 822-829
    • Fonseca, R.J.1    Mourão, P.A.2
  • 105
    • 0037378446 scopus 로고    scopus 로고
    • Depolymerized holothurian glycosaminoglycan (DHG), a novel alternative anticoagulant for hemodialysis, is safe and effective in a dog renal failure model
    • Minamiguchi K, Kitazato KT, Nagase H, Sasaki E, Ohwada K, Kitazato K. Depolymerized holothurian glycosaminoglycan (DHG), a novel alternative anticoagulant for hemodialysis, is safe and effective in a dog renal failure model. Kidney Intern 2003;63:1548-1555.
    • (2003) Kidney Intern , vol.63 , pp. 1548-1555
    • Minamiguchi, K.1    Kitazato, K.T.2    Nagase, H.3    Sasaki, E.4    Ohwada, K.5    Kitazato, K.6
  • 106
    • 0030601735 scopus 로고    scopus 로고
    • High affinity of a fucosylated chondroitin sulfate for plasma low density lipoprotein
    • Tovar AM, Mourão PA. High affinity of a fucosylated chondroitin sulfate for plasma low density lipoprotein. Atherosclerosis 1996;26:85-195.
    • (1996) Atherosclerosis , vol.26 , pp. 85-195
    • Tovar, A.M.1    Mourão, P.A.2
  • 107
    • 0031047910 scopus 로고    scopus 로고
    • Depolymerized holothurian glycosaminoglycan (DHG) prevents neointimal formation in balloon-injured rat carotid artery
    • Igarashi M, Takeda Y, Mori S, Takahashi K, Fuse T, Yamamura M, Saito Y. Depolymerized holothurian glycosaminoglycan (DHG) prevents neointimal formation in balloon-injured rat carotid artery. Atherosclerosis 1997;129:27-31.
    • (1997) Atherosclerosis , vol.129 , pp. 27-31
    • Igarashi, M.1    Takeda, Y.2    Mori, S.3    Takahashi, K.4    Fuse, T.5    Yamamura, M.6    Saito, Y.7
  • 108
    • 0033861026 scopus 로고    scopus 로고
    • Modulation of vascular human endothelial and rat smooth muscle cell growth by a fucosylated chondroitin sulfate from echinoderm
    • Tapon-Bretaudière J, Drouet B, Matou S, Mourão PA, Bros A, Letourneur D, Fischer AM. Modulation of vascular human endothelial and rat smooth muscle cell growth by a fucosylated chondroitin sulfate from echinoderm. Thromb Haemost 2000;84:332-337.
    • (2000) Thromb Haemost , vol.84 , pp. 332-337
    • Tapon-Bretaudière, J.1    Drouet, B.2    Matou, S.3    Mourão, P.A.4    Bros, A.5    Letourneur, D.6    Fischer, A.M.7
  • 110
    • 78649952842 scopus 로고    scopus 로고
    • Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: A P-selectin-mediated event?
    • Melo-Filho NM, Belmiro CL, Gonçalves RG, Takiya CM, Leite MJ, Pavão MS, Mourão PA. Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: A P-selectin-mediated event? Am J Physiol Renal Physiol 2010;299:F1299-F1307.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. F1299-F1307
    • Melo-Filho, N.M.1    Belmiro, C.L.2    Gonçalves, R.G.3    Takiya, C.M.4    Leite, M.J.5    Pavão, M.S.6    Mourão, P.A.7
  • 111
    • 34447522213 scopus 로고    scopus 로고
    • Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment
    • Borsig L, Wang L, Cavalcante MC, Cardilo-Reis L, Ferreira PL, Mourão PA, Esko JD, Pavão MS. Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment. J Biol Chem 2007;282:14984-14991.
    • (2007) J Biol Chem , vol.282 , pp. 14984-14991
    • Borsig, L.1    Wang, L.2    Cavalcante, M.C.3    Cardilo-Reis, L.4    Ferreira, P.L.5    Mourão, P.A.6    Esko, J.D.7    Pavão, M.S.8
  • 112
    • 84879494650 scopus 로고    scopus 로고
    • Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope
    • Lian W, Wu M, Huang N, Gao N, Xiao C, Li Z, Zhang Z, Zheng Y, Peng W, Zhao J. Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope. Biochim Biophys Acta 2013;1830:4681-4691.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 4681-4691
    • Lian, W.1    Wu, M.2    Huang, N.3    Gao, N.4    Xiao, C.5    Li, Z.6    Zhang, Z.7    Zheng, Y.8    Peng, W.9    Zhao, J.10
  • 113
    • 84881489163 scopus 로고    scopus 로고
    • The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entry
    • Huang N, Wu MY, Zheng CB, Zhu L, Zhao JH, Zheng YT. The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entry. Carbohydr Res 2013;380:64-69.
    • (2013) Carbohydr Res , vol.380 , pp. 64-69
    • Huang, N.1    Wu, M.Y.2    Zheng, C.B.3    Zhu, L.4    Zhao, J.H.5    Zheng, Y.T.6
  • 114
    • 84886679455 scopus 로고    scopus 로고
    • Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant mice
    • Hu S, Chang Y, Wang J, Xue C, Shi D, Xu H, Wang Y. Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant mice. Food Funct 2013;4:1639-1646.
    • (2013) Food Funct , vol.4 , pp. 1639-1646
    • Hu, S.1    Chang, Y.2    Wang, J.3    Xue, C.4    Shi, D.5    Xu, H.6    Wang, Y.7
  • 117
    • 0026670983 scopus 로고
    • Structure of DHG, a depolymerized holothurian glycosaminoglycan from sea cucumber, Stichopus japonicus
    • Yoshida HI, Minami Y. Structure of DHG, a depolymerized holothurian glycosaminoglycan from sea cucumber, Stichopus japonicus. Tetrahedron Lett 1992;33:4959-4962.
    • (1992) Tetrahedron Lett , vol.33 , pp. 4959-4962
    • Yoshida, H.I.1    Minami, Y.2
  • 118
    • 84911487939 scopus 로고    scopus 로고
    • Sea, carbohydrates and clotting: A triad on the road of drug discovery
    • Pomin VH. Sea, carbohydrates and clotting: A triad on the road of drug discovery. Mini Rev Med Chem 2014;14:717-724.
    • (2014) Mini Rev Med Chem , vol.14 , pp. 717-724
    • Pomin, V.H.1
  • 119
    • 84873716581 scopus 로고    scopus 로고
    • Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates
    • Chen S, Li G, Wu N, Guo X, Liao N, Ye X, Liu D, Xue C, Chai W. Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates. Biochim Biophys Acta 2013;1830:3054-3066.
    • (2013) Biochim Biophys Acta , vol.1830 , pp. 3054-3066
    • Chen, S.1    Li, G.2    Wu, N.3    Guo, X.4    Liao, N.5    Ye, X.6    Liu, D.7    Xue, C.8    Chai, W.9
  • 120
    • 84875769078 scopus 로고    scopus 로고
    • Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers
    • Luo L, Wu M, Xu L, Lian W, Xiang J, Lu F, Gao N, Xiao C, Wang S, Zhao J. Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers. Mar Drugs 2013;11:399-417.
    • (2013) Mar Drugs , vol.11 , pp. 399-417
    • Luo, L.1    Wu, M.2    Xu, L.3    Lian, W.4    Xiang, J.5    Lu, F.6    Gao, N.7    Xiao, C.8    Wang, S.9    Zhao, J.10
  • 121
    • 83655163741 scopus 로고    scopus 로고
    • Preparation and anticoagulant activity of a fucosylated polysaccharide sulfate from a sea cucumber Acaudina molpadioidea
    • Ye L, Xu L, Li J. Preparation and anticoagulant activity of a fucosylated polysaccharide sulfate from a sea cucumber Acaudina molpadioidea. Carbohydr Polym 2012;87:2052-2057.
    • (2012) Carbohydr Polym , vol.87 , pp. 2052-2057
    • Ye, L.1    Xu, L.2    Li, J.3
  • 122
    • 80054745034 scopus 로고    scopus 로고
    • Structure and effect of sulfated fucose branches on anticoagulant activity of the fucosylated chondroitin sulfate from sea cucumber Thelenata ananas
    • Wu M, Huang R, Wen D, Gao N, He J, Li Z, Zhao J. Structure and effect of sulfated fucose branches on anticoagulant activity of the fucosylated chondroitin sulfate from sea cucumber Thelenata ananas. Carbohydr Polym 2012;87:862-868.
    • (2012) Carbohydr Polym , vol.87 , pp. 862-868
    • Wu, M.1    Huang, R.2    Wen, D.3    Gao, N.4    He, J.5    Li, Z.6    Zhao, J.7
  • 123
    • 0028921935 scopus 로고
    • Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: Antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin
    • Nagase H, Enjyoji KI, Minamiguchi K, Kitazato KY, Kitazato K, Saito H, Kato H. Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: Antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin. Blood 1995;5:1527-1534.
    • (1995) Blood , vol.5 , pp. 1527-1534
    • Nagase, H.1    Enjyoji, K.I.2    Minamiguchi, K.3    Kitazato, K.Y.4    Kitazato, K.5    Saito, H.6    Kato, H.7
  • 125
    • 0029586967 scopus 로고
    • A unique dermatan sulfate-like glycosaminoglycan from ascidian. Its structure and the effect of its unusual sulfation pattern on anticoagulant activity
    • Pavão MS, Mourão PA, Mulloy B, Tollefsen DM. A unique dermatan sulfate-like glycosaminoglycan from ascidian. Its structure and the effect of its unusual sulfation pattern on anticoagulant activity. J Biol Chem 1995;270:31027-31036.
    • (1995) J Biol Chem , vol.270 , pp. 31027-31036
    • Pavão, M.S.1    Mourão, P.A.2    Mulloy, B.3    Tollefsen, D.M.4
  • 126
    • 0036516533 scopus 로고    scopus 로고
    • Structure and anticoagulant properties of sulfated glycosaminoglycans from primitive Chordates
    • Pavão MS. Structure and anticoagulant properties of sulfated glycosaminoglycans from primitive Chordates. An Acad Bras Cienc 2002;74:105-112.
    • (2002) An Acad Bras Cienc , vol.74 , pp. 105-112
    • Pavão, M.S.1
  • 128
    • 80052401501 scopus 로고    scopus 로고
    • Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P-selectin
    • Kozlowski EO, Pavao MS, Borsig L. Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P-selectin. J Thromb Haemost 2011;9:1807-1815.
    • (2011) J Thromb Haemost , vol.9 , pp. 1807-1815
    • Kozlowski, E.O.1    Pavao, M.S.2    Borsig, L.3


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