Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope

Biochimica et Biophysica Acta - General Subjects

Volumn 1830, Issue 10, 2013, Pages 4681-4691

  Lian, Wu ^a,b   Wu, Mingyi ^a   Huang, Ning ^c   Gao, Na ^a   Xiao, Chuang ^a,b   Li, Zi ^a   Zhang, Zhigang ^a   Zheng, Yongtang ^c   Peng, Wenlie ^b   Zhao, Jinhua ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c KUNMING INSTITUTE OF ZOOLOGY   (China)

Author keywords

Anti human immunodeficiency virus activity; Biolayer interferometry; Cluster of Differentiation 4 induced epitope; Envelope glycoprotein 120; Glycosaminoglycan; Structure activity relationship

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTICOAGULANT AGENT; CD4 ANTIGEN; DEXTRAN SULFATE; EPITOPE; FUCOSYLATED GLYCOSAMINOGLYCAN; GAG PROTEIN; GLYCOPROTEIN GP 120; HEPARIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 17B; UNCLASSIFIED DRUG;

ANTICOAGULATION; ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ECHINODERM; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MOLECULAR SIZE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; VIRUS ENTRY; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS STRAIN;

ACTIVATED PARTIAL THROMBOPLASTIN TIME; AMINE REACTIVE SECOND-GENERATION; ANTI-HUMAN IMMUNODEFICIENCY VIRUS ACTIVITY; APTT; AR2G; BIOLAYER INTERFEROMETRY; BLI; CLUSTER OF DIFFERENTIATION 4 INDUCED EPITOPE; DEPOLYMERIZED FUCOSYLATED GLYCOSAMINOGLYCAN; DFG; ENVELOPE GLYCOPROTEIN 120; FG; FUCOSYLATED GLYCOSAMINOGLYCAN; GLYCOSAMINOGLYCAN; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; MOLECULAR WEIGHT; MW; SA; STREPTAVIDIN BIOSENSORS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALS; ANTI-HIV AGENTS; ANTIGENS, CD4; CELL LINE; ECHINODERMATA; EPITOPES; FUCOSE; GLYCOSAMINOGLYCANS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; MOLECULAR WEIGHT; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

ECHINODERMATA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84879494650     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2013.06.003     Document Type: Article

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