메뉴 건너뛰기




Volumn 9, Issue 9, 2014, Pages

The protective role of fucosylated chondroitin sulfate, a distinct glycosaminoglycan, in a murine model of streptozotocin-induced diabetic nephropathy

Author keywords

[No Author keywords available]

Indexed keywords

AGRIN; CHONDROITIN SULFATE; COLLAGEN TYPE 18; ENOXAPARIN; GLUCOSE; GLYCOSAMINOGLYCAN; HEPARANASE; HEPARANASE 1; NESTIN; PERLECAN; PROTEOGLYCAN; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; COLLAGEN; FUCOSYLATED CHONDROITIN SULFATE;

EID: 84907000344     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106929     Document Type: Article
Times cited : (16)

References (59)
  • 1
    • 75649140890 scopus 로고    scopus 로고
    • Diabetic kidney disease: Act now or pay later
    • Atkins RC, Zimmet P (2010) Diabetic kidney disease: act now or pay later. Nephrol Dial Transplant 25: 331-333.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 331-333
    • Atkins, R.C.1    Zimmet, P.2
  • 2
    • 10644259663 scopus 로고    scopus 로고
    • From hyperglycemia to diabetic kidney disease: The role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
    • Schrijvers BF, De Vriese AS, Flyvbjerg A (2004) From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines. Endocr Rev 25: 971-1010.
    • (2004) Endocr Rev , vol.25 , pp. 971-1010
    • Schrijvers, B.F.1    De Vriese, A.S.2    Flyvbjerg, A.3
  • 3
    • 42149122041 scopus 로고    scopus 로고
    • Properties of the glomerular barrier and mechanisms of proteinuria
    • Haraldsson B, Nyström J, Deen WM (2008) Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88: 451-487.
    • (2008) Physiol Rev , vol.88 , pp. 451-487
    • Haraldsson, B.1    Nyström, J.2    Deen, W.M.3
  • 5
    • 45249108429 scopus 로고    scopus 로고
    • Proteinuria in diabetic kidney disease: A mechanistic viewpoint
    • Jefferson JA, Shanklandand SJ, Pichler RH (2008) Proteinuria in diabetic kidney disease: A mechanistic viewpoint. Kidney Int 74: 22-36.
    • (2008) Kidney Int , vol.74 , pp. 22-36
    • Jefferson, J.A.1    Shanklandand, S.J.2    Pichler, R.H.3
  • 6
    • 0019304713 scopus 로고
    • Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion
    • Kanwar YS, Linker A, Farquhar MG (1980) Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion. J Cell Biol 86: 688-693.
    • (1980) J Cell Biol , vol.86 , pp. 688-693
    • Kanwar, Y.S.1    Linker, A.2    Farquhar, M.G.3
  • 7
    • 0026542409 scopus 로고
    • A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats
    • van den Born J, van den Heuvel LP, Bakker MA, Veerkamp JH, Assmann KJ, et al. (1992) A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats. Kidney Int 41: 115-123.
    • (1992) Kidney Int , vol.41 , pp. 115-123
    • Van Den-Born, J.1    Van Den-Heuvel, L.P.2    Bakker, M.A.3    Veerkamp, J.H.4    Assmann, K.J.5
  • 8
    • 0028297289 scopus 로고
    • Expression of glomerular extracellular matrix components in human diabetic nephropathy: Decrease of heparan sulfate in the glomerular basement membrane
    • Tamsma JT, van den Born J, Bruijn JA, Assmann KJ, Weening JJ, et al. (1994) Expression of glomerular extracellular matrix components in human diabetic nephropathy: decrease of heparan sulfate in the glomerular basement membrane. Diabetologia 37: 313-320.
    • (1994) Diabetologia , vol.37 , pp. 313-320
    • Tamsma, J.T.1    Van Den-Born, J.2    Bruijn, J.A.3    Assmann, K.J.4    Weening, J.J.5
  • 9
    • 33947254378 scopus 로고    scopus 로고
    • In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria
    • Wijnhoven TJ, Lensen JF, Wismans RG, Lamrani M, Monnens LA, et al. (2007) In vivo degradation of heparan sulfates in the glomerular basement membrane does not result in proteinuria. J Am Soc Nephrol 18: 823-832.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 823-832
    • Wijnhoven, T.J.1    Lensen, J.F.2    Wismans, R.G.3    Lamrani, M.4    Monnens, L.A.5
  • 11
    • 67651089928 scopus 로고    scopus 로고
    • Glomerular filtration is normal in the absence of both agrin and perlecanheparan sulfate from the glomerular basement membrane
    • Goldberg S, Harvey SJ, Cunningham J, Tryggvason K, Miner JH (2009) Glomerular filtration is normal in the absence of both agrin and perlecanheparan sulfate from the glomerular basement membrane. Nephrol Dial Transplant 24: 2044-2051.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2044-2051
    • Goldberg, S.1    Harvey, S.J.2    Cunningham, J.3    Tryggvason, K.4    Miner, J.H.5
  • 12
    • 38149061339 scopus 로고    scopus 로고
    • Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria
    • van den Hoven MJ, Wijnhoven TJ, Li JP, Zcharia E, Dijkman HB, et al. (2008) Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria. Kidney Int 73: 278-287.
    • (2008) Kidney Int , vol.73 , pp. 278-287
    • Van Den-Hoven, M.J.1    Wijnhoven, T.J.2    Li, J.P.3    Zcharia, E.4    Dijkman, H.B.5
  • 13
    • 34547680445 scopus 로고    scopus 로고
    • Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity
    • Harvey SJ, Jarad G, Cunningham J, Rops AL, van der Vlag J, et al. Disruption of glomerular basement membrane charge through podocyte-specific mutation of agrin does not alter glomerular permselectivity. Am J Pathol 2007; 171: 139-152.
    • (2007) Am J Pathol , vol.171 , pp. 139-152
    • Harvey, S.J.1    Jarad, G.2    Cunningham, J.3    Rops, A.L.4    Van Der-Vlag, J.5
  • 15
    • 21344458126 scopus 로고    scopus 로고
    • Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: Potential role in the pathogenesis of proteinuria in diabetic patients
    • Maxhimer JB, Somenek M, Rao G, Pesce CE, Baldwin D Jr, et al. (2005) Heparanase-1 gene expression and regulation by high glucose in renal epithelial cells: potential role in the pathogenesis of proteinuria in diabetic patients. Diabetes 54: 2172-2178.
    • (2005) Diabetes , vol.54 , pp. 2172-2178
    • Maxhimer, J.B.1    Somenek, M.2    Rao, G.3    Pesce, C.E.4    Baldwin, D.5
  • 17
    • 79952066491 scopus 로고    scopus 로고
    • Heparanase levels are elevated in the urine and plasma of type 2 diabetes patients and associate with blood glucose levels
    • Shafat I, Ilan N, Zoabi S, Vlodavsky I, Nakhoul F (2011) Heparanase Levels Are Elevated in the Urine and Plasma of Type 2 Diabetes Patients and Associate with Blood Glucose Levels. PLoS One 6: e17312.
    • (2011) PLoS One , vol.6 , pp. e17312
    • Shafat, I.1    Ilan, N.2    Zoabi, S.3    Vlodavsky, I.4    Nakhoul, F.5
  • 18
    • 84555188487 scopus 로고    scopus 로고
    • Heparanase is essential for the development of diabetic nephropathy in mice
    • Gil N, Goldberg R, Neuman T, Garsen M, Zcharia E, et al. (2012) Heparanase is essential for the development of diabetic nephropathy in mice. Diabetes 61: 208-216.
    • (2012) Diabetes , vol.61 , pp. 208-216
    • Gil, N.1    Goldberg, R.2    Neuman, T.3    Garsen, M.4    Zcharia, E.5
  • 19
  • 21
    • 77951727161 scopus 로고    scopus 로고
    • Glycosaminoglycan treatment in glomerulonephritis? An interesting option to investigate
    • Gambaro G, Kong NC (2010) Glycosaminoglycan treatment in glomerulonephritis? An interesting option to investigate. J Nephrol 23: 244-252.
    • (2010) J Nephrol , vol.23 , pp. 244-252
    • Gambaro, G.1    Kong, N.C.2
  • 22
    • 33646191735 scopus 로고    scopus 로고
    • Effects of low molecular weight heparin in obstructed kidneys: Decrease of collagen, fibronectin and TGF-beta, and increase of chondroitin/dermatan sulfate proteoglycans and macrophage infiltration
    • Pecly IM, Gonçalves RG, Rangel EP, Takiya CM, Taboada FS, et al. (2006) Effects of low molecular weight heparin in obstructed kidneys: decrease of collagen, fibronectin and TGF-beta, and increase of chondroitin/dermatan sulfate proteoglycans and macrophage infiltration. Nephrol Dial Transplant 21: 1212-1222.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1212-1222
    • Pecly, I.M.1    Gonçalves, R.G.2    Rangel, E.P.3    Takiya, C.M.4    Taboada, F.S.5
  • 23
    • 0042521148 scopus 로고    scopus 로고
    • Heparin reduces glomerular infiltration and TGF-beta protein expression by macrophages in puromycin glomerulosclerosis
    • Ceol M, Vianello D, Schleicher E, Anglani F, Barbanti M, et al. (2003) Heparin reduces glomerular infiltration and TGF-beta protein expression by macrophages in puromycin glomerulosclerosis. J Nephrol 16: 210-218.
    • (2003) J Nephrol , vol.16 , pp. 210-218
    • Ceol, M.1    Vianello, D.2    Schleicher, E.3    Anglani, F.4    Barbanti, M.5
  • 24
    • 0028092966 scopus 로고
    • Treatment with a glycosaminoglycan formulation ameliorates experimental diabetic nephropathy
    • Gambaro G, Venturini AP, Noonan DM, Fries W, Re G, et al. (1994) Treatment with a glycosaminoglycan formulation ameliorates experimental diabetic nephropathy. Kidney Int 46: 797-806.
    • (1994) Kidney Int , vol.46 , pp. 797-806
    • Gambaro, G.1    Venturini, A.P.2    Noonan, D.M.3    Fries, W.4    Re, G.5
  • 25
    • 0033672331 scopus 로고    scopus 로고
    • Glycosaminoglycan therapy prevents TGF-beta1 overexpression and pathologic changes in renal tissue of long-term diabetic rats
    • Ceol M, Gambaro G, Sauer U, Baggio B, Anglani F, et al. (2000) Glycosaminoglycan therapy prevents TGF-beta1 overexpression and pathologic changes in renal tissue of long-term diabetic rats. J Am Soc Nephrol 11: 2324-2336.
    • (2000) J Am Soc Nephrol , vol.11 , pp. 2324-2336
    • Ceol, M.1    Gambaro, G.2    Sauer, U.3    Baggio, B.4    Anglani, F.5
  • 26
    • 84872785696 scopus 로고    scopus 로고
    • Sulodexide decreases albuminuria and regulates matrix protein accumulation in C57BL/6 mice with streptozotocin-induced type I diabetic nephropathy
    • Yung S, Chau MK, Zhang Q, Zhang CZ, Chan TM (2013) Sulodexide decreases albuminuria and regulates matrix protein accumulation in C57BL/6 mice with streptozotocin-induced type I diabetic nephropathy. PLoS One 8: e54501.
    • (2013) PLoS One , vol.8 , pp. e54501
    • Yung, S.1    Chau, M.K.2    Zhang, Q.3    Zhang, C.Z.4    Chan, T.M.5
  • 27
    • 84867669140 scopus 로고    scopus 로고
    • A new mechanism of action of sulodexide in diabetic nephropathy: Inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition
    • Masola V, Onisto M, Zaza G, Lupo A, Gambaro G (2012) A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition. J Transl Med 10: 213.
    • (2012) J Transl Med , vol.10 , pp. 213
    • Masola, V.1    Onisto, M.2    Zaza, G.3    Lupo, A.4    Gambaro, G.5
  • 28
    • 0035722285 scopus 로고    scopus 로고
    • Lowmolecular- weight heparin prevents high glucose- and phorbol ester-induced TGF-beta 1 gene activation
    • Weigert C, Brodbeck K, Häring HU, Gambaro G, Schleicher ED (2001) Lowmolecular- weight heparin prevents high glucose- and phorbol ester-induced TGF-beta 1 gene activation. Kidney Int 60: 935-943.
    • (2001) Kidney Int , vol.60 , pp. 935-943
    • Weigert, C.1    Brodbeck, K.2    Häring, H.U.3    Gambaro, G.4    Schleicher, E.D.5
  • 29
    • 79960246274 scopus 로고    scopus 로고
    • Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: Biochemical and structural considerations
    • Bacilieri M, Naggi A, Ceol M, Schleicher ED, Tosetto E, et al. (2011) Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: biochemical and structural considerations. Glycobiology 21: 1029-1037.
    • (2011) Glycobiology , vol.21 , pp. 1029-1037
    • Bacilieri, M.1    Naggi, A.2    Ceol, M.3    Schleicher, E.D.4    Tosetto, E.5
  • 30
    • 0030719936 scopus 로고    scopus 로고
    • A randomized, controlled study of sulodexide therapy for the treatment of diabetic nephropathy
    • Dedov I, Shestakova M, Vorontzov A, Palazzini E (1997) A randomized, controlled study of sulodexide therapy for the treatment of diabetic nephropathy. Nephrol Dial Transplant 12: 2295-2300.
    • (1997) Nephrol Dial Transplant , vol.12 , pp. 2295-2300
    • Dedov, I.1    Shestakova, M.2    Vorontzov, A.3    Palazzini, E.4
  • 31
    • 0036014944 scopus 로고    scopus 로고
    • Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: The Di.N.A.S. Randomized trial
    • Gambaro G, Kinalska I, Oksa A, Pont'uch P, Hertlová M, et al. (2002) Oral sulodexide reduces albuminuria in microalbuminuric and macroalbuminuric type 1 and type 2 diabetic patients: the Di.N.A.S. randomized trial. J Am Soc Nephrol 13: 1615-1625.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1615-1625
    • Gambaro, G.1    Kinalska, I.2    Oksa, A.3    Pont'uch, P.4    Hertlová, M.5
  • 32
    • 77955440687 scopus 로고    scopus 로고
    • Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy
    • Blouza S, Dakhli S, Abid H, Aissaoui M, Ardhaoui I, et al. (2010) Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy. J Nephrol 23: 415-424.
    • (2010) J Nephrol , vol.23 , pp. 415-424
    • Blouza, S.1    Dakhli, S.2    Abid, H.3    Aissaoui, M.4    Ardhaoui, I.5
  • 33
    • 80055018022 scopus 로고    scopus 로고
    • Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: A randomized controlled trial
    • Lewis EJ, Lewis JB, Greene T, Hunsicker LG, Berl T, et al. (2011) Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: a randomized controlled trial. Am J Kidney Dis 58: 729-736.
    • (2011) Am J Kidney Dis , vol.58 , pp. 729-736
    • Lewis, E.J.1    Lewis, J.B.2    Greene, T.3    Hunsicker, L.G.4    Berl, T.5
  • 34
    • 84863393468 scopus 로고    scopus 로고
    • Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy
    • Packham DK, Wolfe R, Reutens AT, Berl T, Heerspink HL, et al. (2012) Sulodexide fails to demonstrate renoprotection in overt type 2 diabetic nephropathy. J Am Soc Nephrol 23: 123-130.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 123-130
    • Packham, D.K.1    Wolfe, R.2    Reutens, A.T.3    Berl, T.4    Heerspink, H.L.5
  • 35
    • 84862632961 scopus 로고    scopus 로고
    • Discounting the efficacy of sulodexide in diabetic nephropathy is premature
    • Gambaro G (2012) Discounting the efficacy of sulodexide in diabetic nephropathy is premature. Am J Kidney Dis 60: 169-170.
    • (2012) Am J Kidney Dis , vol.60 , pp. 169-170
    • Gambaro, G.1
  • 36
    • 0031831742 scopus 로고    scopus 로고
    • Antithrombotic activity of a fucosylated chondroitin sulfate from echinoderm: Sulfated fucose branches on the polysaccharide account for its antithrombotic action
    • Mourão PA, Guimarães B, Mulloy B, Thomas S, Gray E (1998) Antithrombotic activity of a fucosylated chondroitin sulfate from echinoderm: sulfated fucose branches on the polysaccharide account for its antithrombotic action. Br J Haematol 101: 647-652.
    • (1998) Br J Haematol , vol.101 , pp. 647-652
    • Mourão, P.A.1    Guimarães, B.2    Mulloy, B.3    Thomas, S.4    Gray, E.5
  • 37
    • 34447522213 scopus 로고    scopus 로고
    • Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment
    • Borsig L, Wang L, Cavalcante MC, Cardilo-Reis L, Ferreira PL, et al. (2007) Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment. J Biol Chem 282: 14984-14991.
    • (2007) J Biol Chem , vol.282 , pp. 14984-14991
    • Borsig, L.1    Wang, L.2    Cavalcante, M.C.3    Cardilo-Reis, L.4    Ferreira, P.L.5
  • 38
    • 78649952842 scopus 로고    scopus 로고
    • Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: A P-selectin-mediated event?
    • Melo-Filho NM, Belmiro CL, Gonçalves RG, Takiya CM, Leite M Jr, et al. (2010) Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: a P-selectin-mediated event? Am J Physiol Renal Physiol 299: F1299-F1307.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. F1299-F1307
    • Melo-Filho, N.M.1    Belmiro, C.L.2    Gonçalves, R.G.3    Takiya, C.M.4    Leite, M.5
  • 39
    • 33646376214 scopus 로고    scopus 로고
    • Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes
    • Chen J, Boyle S, Zhao M, Su W, Takahashi K, et al. (2006) Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. J Am Soc Nephrol 17: 1283-1291.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1283-1291
    • Chen, J.1    Boyle, S.2    Zhao, M.3    Su, W.4    Takahashi, K.5
  • 40
    • 84907003882 scopus 로고    scopus 로고
    • Accessed 19 September 2011
    • Mesangial index quantification. Animal Models of Diabetic Complications Consortium (2008) Available: www.amdcc.org/shared/showFile. aspx?doctypeid=3&docid=64. Accessed 19 September 2011.
    • (2008) Animal Models of Diabetic Complications Consortium
  • 42
    • 84867576816 scopus 로고    scopus 로고
    • Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy
    • Weil EJ, Lemley KV, Mason CC, Yee B, Jones Ll, et al. (2012) Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy. Kidney Int 82: 1010-1017.
    • (2012) Kidney Int , vol.82 , pp. 1010-1017
    • Weil, E.J.1    Lemley, K.V.2    Mason, C.C.3    Yee, B.4    Jones, L.L.5
  • 43
    • 20044362239 scopus 로고    scopus 로고
    • From the periphery of the glomerular capillary wall toward the center of disease: Podocyte injury comes of age in diabetic nephropathy
    • Wolf G, Chen S, Ziyadeh FN (2005) From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54: 1626-1634.
    • (2005) Diabetes , vol.54 , pp. 1626-1634
    • Wolf, G.1    Chen, S.2    Ziyadeh, F.N.3
  • 44
    • 69249158624 scopus 로고    scopus 로고
    • Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species
    • van den Hoven MJ, Waanders F, Rops AL, Kramer AB, van Goor H, et al. (2009) Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species. Nephrol Dial Transplant 24: 2637-2645.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2637-2645
    • Van Den-Hoven, M.J.1    Waanders, F.2    Rops, A.L.3    Kramer, A.B.4    Van Goor, H.5
  • 45
    • 0032863737 scopus 로고    scopus 로고
    • Inhibition of glomerular cell apoptosis by heparin
    • Ishikawa Y, Kitamura M (1999) Inhibition of glomerular cell apoptosis by heparin. Kidney Int 56: 954-963.
    • (1999) Kidney Int , vol.56 , pp. 954-963
    • Ishikawa, Y.1    Kitamura, M.2
  • 46
    • 0035021506 scopus 로고    scopus 로고
    • Decreased glomerular expression of agrin in diabetic nephropathy and podocytes, cultured in high glucose medium
    • Yard BA, Kahlert S, Engelleiter R, Resch S, Waldherr R, et al. (2001) Decreased glomerular expression of agrin in diabetic nephropathy and podocytes, cultured in high glucose medium. Exp Nephrol 9: 214-222.
    • (2001) Exp Nephrol , vol.9 , pp. 214-222
    • Yard, B.A.1    Kahlert, S.2    Engelleiter, R.3    Resch, S.4    Waldherr, R.5
  • 47
    • 84885305158 scopus 로고    scopus 로고
    • Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin
    • Han J, Hiebert LM. (2013) Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin. Vascular Pharmacology 59: 112-118.
    • (2013) Vascular Pharmacology , vol.59 , pp. 112-118
    • Han, J.1    Hiebert, L.M.2
  • 48
    • 0037088587 scopus 로고    scopus 로고
    • Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: Role of GAbinding protein and Sp1 in regulating HPR1 basal promoter activity
    • Jiang P, Kumar A, Parrillo JE, Dempsey LA, Platt JL, et al. (2002) Cloning and characterization of the human heparanase-1 (HPR1) gene promoter: role of GAbinding protein and Sp1 in regulating HPR1 basal promoter activity. J Biol Chem 277: 8989-8998.
    • (2002) J Biol Chem , vol.277 , pp. 8989-8998
    • Jiang, P.1    Kumar, A.2    Parrillo, J.E.3    Dempsey, L.A.4    Platt, J.L.5
  • 49
    • 0024470511 scopus 로고
    • Retention of glomerular basement membrane-proteoglycans accompanying loss of anionic site staining in experimental diabetes
    • Templeton DM (1989) Retention of glomerular basement membrane-proteoglycans accompanying loss of anionic site staining in experimental diabetes. Lab Invest 61: 202-211.
    • (1989) Lab Invest , vol.61 , pp. 202-211
    • Templeton, D.M.1
  • 50
    • 27844520213 scopus 로고    scopus 로고
    • Synthesis of anticoagulantly active heparan sulfate proteoglycans by glomerular epithelial cells involves multiple 3-O-sulfotransferase isoforms and a limiting precursor pool
    • Girardin EP, Hajmohammadi S, Birmele B, Helisch A, Shworak NW, et al. (2005) Synthesis of anticoagulantly active heparan sulfate proteoglycans by glomerular epithelial cells involves multiple 3-O-sulfotransferase isoforms and a limiting precursor pool. J Biol Chem 280: 38059-70.
    • (2005) J Biol Chem , vol.280 , pp. 38059-38070
    • Girardin, E.P.1    Hajmohammadi, S.2    Birmele, B.3    Helisch, A.4    Shworak, N.W.5
  • 51
    • 0033838261 scopus 로고    scopus 로고
    • A specific structural alteration in the heparan sulphate of human glomerular basement membrane in diabetes
    • Edge AS, Spiro RG (2000) A specific structural alteration in the heparan sulphate of human glomerular basement membrane in diabetes. Diabetologia 43: 1056-9.
    • (2000) Diabetologia , vol.43 , pp. 1056-1059
    • Edge, A.S.1    Spiro, R.G.2
  • 53
    • 79958827062 scopus 로고    scopus 로고
    • Diabetes results in structural alteration of chondroitin sulfate/dermatan sulfate in the rat kidney: Effects on the binding to extracellular matrix components
    • Joladarashi D, Salimath PV, Chilkunda ND (2011) Diabetes results in structural alteration of chondroitin sulfate/dermatan sulfate in the rat kidney: effects on the binding to extracellular matrix components. Glycobiology 21: 960-72.
    • (2011) Glycobiology , vol.21 , pp. 960-972
    • Joladarashi, D.1    Salimath, P.V.2    Chilkunda, N.D.3
  • 54
    • 84887378158 scopus 로고    scopus 로고
    • Reduced sulfation of chondroitin sulfate but not heparan sulfation kidneys of diabetic db/db mice
    • Reine TM, Grøndahl F, Jenssen TG, Hadler-Olsen E, Prydz K, et al. (2013) Reduced sulfation of chondroitin sulfate but not heparan sulfation kidneys of diabetic db/db mice. J Histochem Cytochem 61: 606-16.
    • (2013) J Histochem Cytochem , vol.61 , pp. 606-616
    • Reine, T.M.1    Grøndahl, F.2    Jenssen, T.G.3    Hadler-Olsen, E.4    Prydz, K.5
  • 55
    • 79955036703 scopus 로고    scopus 로고
    • Changes in cardiac heparan sulfate proteoglycan expression and streptozotocin-induced diastolic dysfunction in rats
    • Strunz CM, Matsuda M, Salemi VM, Nogueira A, Mansur AP, et al (2011) Changes in cardiac heparan sulfate proteoglycan expression and streptozotocin-induced diastolic dysfunction in rats. Cardiovasc Diabetol 25; 10: 35.
    • (2011) Cardiovasc Diabetol , vol.25 , Issue.10 , pp. 35
    • Strunz, C.M.1    Matsuda, M.2    Salemi, V.M.3    Nogueira, A.4    Mansur, A.P.5
  • 56
    • 0031788344 scopus 로고    scopus 로고
    • Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose
    • Mogyorosi A, Ziyadeh FN (1998) Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose. Am J Physiol Renal Physiol 275: F827-F832.
    • (1998) Am J Physiol Renal Physiol , vol.275 , pp. F827-F832
    • Mogyorosi, A.1    Ziyadeh, F.N.2
  • 57
    • 84908593660 scopus 로고    scopus 로고
    • Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis
    • Apr 23
    • Rops A, Loeven MA, van Gemst JJ, Eversen I, Van Wijk XM, et al. (2014) Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis. Kidney Int Apr 23. doi:10.1038/ki.2014.115.
    • (2014) Kidney Int
    • Rops, A.1    Loeven, M.A.2    Van Gemst, J.J.3    Eversen, I.4    Van Wijk, X.M.5
  • 58
    • 33746747093 scopus 로고    scopus 로고
    • Functional and molecular alterations of the glomerular barrier in long-term diabetes in mice
    • Jeansson M, Granqvist AB, Nyström JS, Haraldsson B (2006) Functional and molecular alterations of the glomerular barrier in long-term diabetes in mice. Diabetologia 49: 2200-2209.
    • (2006) Diabetologia , vol.49 , pp. 2200-2209
    • Jeansson, M.1    Granqvist, A.B.2    Nyström, J.S.3    Haraldsson, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.