Antitumor properties of a new non-anticoagulant heparin analog from the mollusk Nodipecten nodosus: Effect on P-selectin, heparanase, metastasis and cellular recruitment

Glycobiology

Volumn 25, Issue 4, 2015, Pages 386-393

  Gomes, Angélica Maciel ^a   Kozlowski, Eliene Oliveira ^a   Borsig, Lubor ^b   Teixeira, Felipe C O B ^a   Vlodavsky, Israel ^c   Pavão, Mauro S G ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

anti cancer activity; heparanase; mollusk heparan sulfate; P selectin

Indexed keywords

GLYCAN; HEPARAN SULFATE; HEPARANASE; HEPARIN; PADGEM PROTEIN; ANTICOAGULANT AGENT; ANTINEOPLASTIC AGENT; BETA GLUCURONIDASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCHEMICAL ANALYSIS; CELL ADHESION; CELL INVASION; COLON CARCINOMA; COMPLEX FORMATION; CONTROLLED STUDY; DRUG MECHANISM; ENDOTHELIUM; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; INFLAMMATION; INFLAMMATORY CELL; LEUKOCYTE ROLLING; LEWIS LUNG CARCINOMA CELL; LUNG METASTASIS; MALE; METASTASIS INHIBITION; MOLLUSC; MOUSE; NODIPECTEN NODOSUS; NONHUMAN; PRIORITY JOURNAL; RAT; THIOGLYCOLATE-INDUCED PERITONITIS; THROMBOCYTE; TUMOR GROWTH; ANIMAL; ANTAGONISTS AND INHIBITORS; CANCER TRANSPLANTATION; CARCINOMA, LEWIS LUNG; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; IC50; LUNG NEOPLASMS; METABOLISM; PHYSIOLOGY; SECONDARY; TUMOR CELL LINE;

ANIMALS; ANTICOAGULANTS; ANTINEOPLASTIC AGENTS; BLOOD PLATELETS; CARCINOMA, LEWIS LUNG; CELL ADHESION; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GLUCURONIDASE; HEPARITIN SULFATE; HUMANS; INHIBITORY CONCENTRATION 50; LEUKOCYTE ROLLING; LUNG NEOPLASMS; MOLLUSCA; NEOPLASM TRANSPLANTATION; P-SELECTIN;

EID: 84941053916     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwu119     Document Type: Article

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