Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant action

Journal of Biological Chemistry

Volumn 271, Issue 39, 1996, Pages 23973-23984

  Mourao, Paulo A S ^a   Pereira, Mariana S ^a   Pavo, Mauro S G ^a   Mulloy, Barbara ^b   Tollefsen, Douglas M ^c   Mowinckel, Marie Christine ^d   Abildgaard, Ulrich ^d  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d AKER UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN; CHONDROITIN ABC LYASE; CHONDROITIN SULFATE; DERMATAN SULFATE; HEPARIN COFACTOR II; POLYSACCHARIDE;

ANTICOAGULATION; ARTICLE; CHEMICAL STRUCTURE; ECHINODERM; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; THROMBOSIS; THROMBOSIS PREVENTION;

ANIMALS; ANTICOAGULANTS; ANTITHROMBIN III; CHONDROITIN SULFATES; CHROMATOGRAPHY, THIN LAYER; ENZYME INHIBITORS; FUCOSE; HEPARIN COFACTOR II; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PARTIAL THROMBOPLASTIN TIME; SEA CUCUMBERS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 0029796369     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.39.23973     Document Type: Article

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