메뉴 건너뛰기




Volumn 36, Issue 10, 2015, Pages 688-704

Erratum: Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma (Trends in Pharmacological Sciences (2015) 36 (688-704) DOI: 10.1016/j.tips.2015.06.010);Ligands for the Nuclear Peroxisome Proliferator-Activated Receptor Gamma

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12 14 PGJ2; 2,4 THIAZOLIDINEDIONE DERIVATIVE; AMORFRUTIN A; AMORFRUTIN B; LIGAND; MESALAZINE; MRL 24; OLSALAZINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; ROSIGLITAZONE; SR 1664; SR 1824; TELMISARTAN; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; PROTEIN BINDING;

EID: 84943411002     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2015.12.002     Document Type: Erratum
Times cited : (96)

References (106)
  • 1
    • 0012473279 scopus 로고
    • The nuclear receptor superfamily: The second decade
    • D.J. Mangelsdorf, and et al. The nuclear receptor superfamily: the second decade Cell 83 1995 835 839
    • (1995) Cell , vol.83 , pp. 835-839
    • Mangelsdorf, D.J.1
  • 2
    • 25444504005 scopus 로고    scopus 로고
    • A Nuclear Receptor Atlas: 3T3-L1 adipogenesis
    • M. Fu, and et al. A Nuclear Receptor Atlas: 3T3-L1 adipogenesis Mol. Endocrinol. 19 2005 2437 2450
    • (2005) Mol. Endocrinol. , vol.19 , pp. 2437-2450
    • Fu, M.1
  • 3
    • 14544303179 scopus 로고    scopus 로고
    • PPAR gamma, 10 years later
    • M.A. Lazar PPAR gamma, 10 years later Biochimie 87 2005 9 13
    • (2005) Biochimie , vol.87 , pp. 9-13
    • Lazar, M.A.1
  • 4
    • 77956018353 scopus 로고    scopus 로고
    • Revisiting the rosiglitazone story - Lessons learned
    • C.J. Rosen Revisiting the rosiglitazone story - lessons learned N. Engl. J. Med. 363 2010 803 806
    • (2010) N. Engl. J. Med. , vol.363 , pp. 803-806
    • Rosen, C.J.1
  • 5
    • 25444448223 scopus 로고    scopus 로고
    • A Nuclear Receptor Atlas: Macrophage activation
    • G.D. Barish, and et al. A Nuclear Receptor Atlas: macrophage activation Mol. Endocrinol. 19 2005 2466 2477
    • (2005) Mol. Endocrinol. , vol.19 , pp. 2466-2477
    • Barish, G.D.1
  • 6
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • M. Lehrke, and M.A. Lazar The many faces of PPARgamma Cell 123 2005 993 999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 7
    • 36048950218 scopus 로고    scopus 로고
    • Adipogenesis and lipotoxicity: Role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1)
    • G. Medina-Gomez, and et al. Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1) Public Health Nutr. 10 2007 1132 1137
    • (2007) Public Health Nutr. , vol.10 , pp. 1132-1137
    • Medina-Gomez, G.1
  • 8
    • 20044380758 scopus 로고    scopus 로고
    • The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform
    • G. Medina-Gomez, and et al. The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform Diabetes 54 2005 1706 1716
    • (2005) Diabetes , vol.54 , pp. 1706-1716
    • Medina-Gomez, G.1
  • 9
    • 76049086229 scopus 로고    scopus 로고
    • PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization
    • S. Sugii, and et al. PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization Proc. Natl. Acad. Sci. U.S.A. 106 2009 22504 22509
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 22504-22509
    • Sugii, S.1
  • 10
    • 78650317248 scopus 로고    scopus 로고
    • Endogenous ligands for nuclear receptors: Digging deeper
    • M. Schupp, and M.A. Lazar Endogenous ligands for nuclear receptors: digging deeper J. Biol. Chem. 285 2010 40409 40415
    • (2010) J. Biol. Chem. , vol.285 , pp. 40409-40415
    • Schupp, M.1    Lazar, M.A.2
  • 11
    • 84883253449 scopus 로고    scopus 로고
    • Acute genome-wide effects of rosiglitazone on PPARgamma transcriptional networks in adipocytes
    • A.K. Haakonsson, and et al. Acute genome-wide effects of rosiglitazone on PPARgamma transcriptional networks in adipocytes Mol. Endocrinol. 27 2013 1536 1549
    • (2013) Mol. Endocrinol. , vol.27 , pp. 1536-1549
    • Haakonsson, A.K.1
  • 12
    • 8844262660 scopus 로고    scopus 로고
    • Principles for modulation of the nuclear receptor superfamily
    • H. Gronemeyer, and et al. Principles for modulation of the nuclear receptor superfamily Nat. Rev. Drug Discov. 3 2004 950 964
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 950-964
    • Gronemeyer, H.1
  • 13
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma
    • E. Hu, and et al. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma Science 274 1996 2100 2103
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1
  • 14
    • 84864615516 scopus 로고    scopus 로고
    • Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma
    • L. Qiang, and et al. Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Ppargamma Cell 150 2012 620 632
    • (2012) Cell , vol.150 , pp. 620-632
    • Qiang, L.1
  • 15
    • 84862777029 scopus 로고    scopus 로고
    • O-GlcNAc modification of PPARgamma reduces its transcriptional activity
    • S. Ji, and et al. O-GlcNAc modification of PPARgamma reduces its transcriptional activity Biochem. Biophys. Res. Commun. 417 2012 1158 1163
    • (2012) Biochem. Biophys. Res. Commun. , vol.417 , pp. 1158-1163
    • Ji, S.1
  • 16
    • 3142716146 scopus 로고    scopus 로고
    • Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification
    • T. Ohshima, and et al. Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification J. Biol. Chem. 279 2004 29551 29557
    • (2004) J. Biol. Chem. , vol.279 , pp. 29551-29557
    • Ohshima, T.1
  • 17
    • 63049133308 scopus 로고    scopus 로고
    • PPAR-gamma AF-2 domain functions as a component of a ubiquitin-dependent degradation signal
    • G.E. Kilroy, and et al. PPAR-gamma AF-2 domain functions as a component of a ubiquitin-dependent degradation signal Obesity 17 2009 665 673
    • (2009) Obesity , vol.17 , pp. 665-673
    • Kilroy, G.E.1
  • 18
    • 84899710827 scopus 로고    scopus 로고
    • Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARgamma-driven enhancers
    • S.E. Step, and et al. Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARgamma-driven enhancers Genes Dev. 28 2014 1018 1028
    • (2014) Genes Dev. , vol.28 , pp. 1018-1028
    • Step, S.E.1
  • 19
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
    • S.A. Kliewer, and et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ Proc. Natl. Acad. Sci. U.S.A. 94 1997 4318 4323
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1
  • 20
    • 0030985318 scopus 로고    scopus 로고
    • Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
    • G. Krey, and et al. Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay Mol. Endocrinol. 11 1997 779 791
    • (1997) Mol. Endocrinol. , vol.11 , pp. 779-791
    • Krey, G.1
  • 21
    • 84902373936 scopus 로고    scopus 로고
    • Amorfrutins: A promising class of natural products that are beneficial to health
    • S. Sauer Amorfrutins: a promising class of natural products that are beneficial to health Chembiochem 15 2014 1231 1238
    • (2014) Chembiochem , vol.15 , pp. 1231-1238
    • Sauer, S.1
  • 22
    • 35148887302 scopus 로고    scopus 로고
    • Partial agonists activate PPARgamma using a helix 12 independent mechanism
    • J.B. Bruning, and et al. Partial agonists activate PPARgamma using a helix 12 independent mechanism Structure 15 2007 1258 1271
    • (2007) Structure , vol.15 , pp. 1258-1271
    • Bruning, J.B.1
  • 23
    • 84878808621 scopus 로고    scopus 로고
    • Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor gamma (PPARgamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes
    • W. Zheng, and et al. Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor gamma (PPARgamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes Diabetologia 56 2013 401 411
    • (2013) Diabetologia , vol.56 , pp. 401-411
    • Zheng, W.1
  • 24
    • 56749130032 scopus 로고    scopus 로고
    • Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA
    • V. Chandra, and et al. Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA Nature 456 2008 350 356
    • (2008) Nature , vol.456 , pp. 350-356
    • Chandra, V.1
  • 25
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: The diverse biology of PPARgamma
    • P. Tontonoz, and B.M. Spiegelman Fat and beyond: the diverse biology of PPARgamma Annu. Rev. Biochem. 77 2008 289 312
    • (2008) Annu. Rev. Biochem. , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 26
    • 33745714392 scopus 로고    scopus 로고
    • PPARs and other nuclear receptors in inflammation
    • G. Rizzo, and S. Fiorucci PPARs and other nuclear receptors in inflammation Curr. Opin. Pharmacol. 6 2006 421 427
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 421-427
    • Rizzo, G.1    Fiorucci, S.2
  • 27
    • 84907990392 scopus 로고    scopus 로고
    • Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes
    • R.E. Soccio, and et al. Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes Cell Metab. 20 2014 573 591
    • (2014) Cell Metab. , vol.20 , pp. 573-591
    • Soccio, R.E.1
  • 28
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • G.S. Hotamisligil, and et al. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance Science 271 1996 665 668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1
  • 30
    • 79952437112 scopus 로고    scopus 로고
    • Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice
    • X. Prieur, and et al. Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice Diabetes 60 2011 797 809
    • (2011) Diabetes , vol.60 , pp. 797-809
    • Prieur, X.1
  • 31
    • 21544479710 scopus 로고    scopus 로고
    • Collecting duct-specific deletion of peroxisome proliferator-activated receptor gamma blocks thiazolidinedione-induced fluid retention
    • H. Zhang, and et al. Collecting duct-specific deletion of peroxisome proliferator-activated receptor gamma blocks thiazolidinedione-induced fluid retention Proc. Natl. Acad. Sci. U.S.A. 102 2005 9406 9411
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 9406-9411
    • Zhang, H.1
  • 32
    • 34547603895 scopus 로고    scopus 로고
    • PPARs and molecular mechanisms of transrepression
    • M. Ricote, and C.K. Glass PPARs and molecular mechanisms of transrepression Biochim. Biophys. Acta 1771 2007 926 935
    • (2007) Biochim. Biophys. Acta , vol.1771 , pp. 926-935
    • Ricote, M.1    Glass, C.K.2
  • 33
    • 0034693323 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B
    • S.W. Chung, and et al. Oxidized low density lipoprotein inhibits interleukin-12 production in lipopolysaccharide-activated mouse macrophages via direct interactions between peroxisome proliferator-activated receptor-gamma and nuclear factor-kappa B J. Biol. Chem. 275 2000 32681 32687
    • (2000) J. Biol. Chem. , vol.275 , pp. 32681-32687
    • Chung, S.W.1
  • 34
    • 0042867242 scopus 로고    scopus 로고
    • Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB
    • H. Ruan, and et al. Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB J. Biol. Chem. 278 2003 28181 28192
    • (2003) J. Biol. Chem. , vol.278 , pp. 28181-28192
    • Ruan, H.1
  • 35
    • 0347756655 scopus 로고    scopus 로고
    • Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
    • D. Kelly, and et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA Nat. Immunol. 5 2004 104 112
    • (2004) Nat. Immunol. , vol.5 , pp. 104-112
    • Kelly, D.1
  • 36
    • 84871766892 scopus 로고    scopus 로고
    • PPARgamma is an E3 ligase that induces the degradation of NFkappaB/p65
    • Y. Hou, and et al. PPARgamma is an E3 ligase that induces the degradation of NFkappaB/p65 Nat. Commun. 3 2012 1300
    • (2012) Nat. Commun. , vol.3 , pp. 1300
    • Hou, Y.1
  • 37
    • 55749101777 scopus 로고    scopus 로고
    • Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
    • R. Nielsen, and et al. Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis Genes Dev. 22 2008 2953 2967
    • (2008) Genes Dev. , vol.22 , pp. 2953-2967
    • Nielsen, R.1
  • 38
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • R.M. Evans, and et al. PPARs and the complex journey to obesity Nat. Med. 10 2004 355 361
    • (2004) Nat. Med. , vol.10 , pp. 355-361
    • Evans, R.M.1
  • 39
    • 33748672081 scopus 로고    scopus 로고
    • Selective PPAR modulators, dual and pan PPAR agonists: Multimodal drugs for the treatment of type 2 diabetes and atherosclerosis
    • B. Pourcet, and et al. Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis Expert Opin. Emerg. Drugs 11 2006 379 401
    • (2006) Expert Opin. Emerg. Drugs , vol.11 , pp. 379-401
    • Pourcet, B.1
  • 40
    • 0034735992 scopus 로고    scopus 로고
    • Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone
    • J. Sakamoto, and et al. Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone Biochem. Biophys. Res. Commun. 278 2000 704 711
    • (2000) Biochem. Biophys. Res. Commun. , vol.278 , pp. 704-711
    • Sakamoto, J.1
  • 41
    • 84860795758 scopus 로고    scopus 로고
    • Amorfrutins are potent antidiabetic dietary natural products
    • C. Weidner, and et al. Amorfrutins are potent antidiabetic dietary natural products Proc. Natl. Acad. Sci. U.S.A. 109 2012 7257 7262
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 7257-7262
    • Weidner, C.1
  • 42
    • 84929493665 scopus 로고    scopus 로고
    • Structure-based virtual screening and discovery of new PPARdelta/gamma dual agonist and PPARdelta and gamma agonists
    • V.G. Maltarollo, and et al. Structure-based virtual screening and discovery of new PPARdelta/gamma dual agonist and PPARdelta and gamma agonists PLoS ONE 10 2015 e0118790
    • (2015) PLoS ONE , vol.10 , pp. e0118790
    • Maltarollo, V.G.1
  • 43
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • J.M. Lehmann, and et al. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma) J. Biol. Chem. 270 1995 12953 12956
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1
  • 44
    • 77951457202 scopus 로고    scopus 로고
    • Fibrates, glitazones, and peroxisome proliferator-activated receptors
    • F. Lalloyer, and B. Staels Fibrates, glitazones, and peroxisome proliferator-activated receptors Arterioscler. Thromb. Vasc. Biol. 30 2010 894 899
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 894-899
    • Lalloyer, F.1    Staels, B.2
  • 45
    • 0032505096 scopus 로고    scopus 로고
    • Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
    • R.T. Nolte, and et al. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma Nature 395 1998 137 143
    • (1998) Nature , vol.395 , pp. 137-143
    • Nolte, R.T.1
  • 46
    • 33244464265 scopus 로고    scopus 로고
    • Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: A systematic review
    • A. Natali, and E. Ferrannini Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review Diabetologia 49 2006 434 441
    • (2006) Diabetologia , vol.49 , pp. 434-441
    • Natali, A.1    Ferrannini, E.2
  • 47
    • 80053361589 scopus 로고    scopus 로고
    • The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact
    • E. Phielix, and et al. The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact Trends Pharmacol. Sci. 32 2011 607 616
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 607-616
    • Phielix, E.1
  • 48
    • 4143075930 scopus 로고    scopus 로고
    • Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: Comparison with metformin
    • J.M. Ye, and et al. Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin Diabetologia 47 2004 1306 1313
    • (2004) Diabetologia , vol.47 , pp. 1306-1313
    • Ye, J.M.1
  • 49
    • 0036255529 scopus 로고    scopus 로고
    • The mode of action of thiazolidinediones
    • H. Hauner The mode of action of thiazolidinediones Diab. Metab. Res. Rev. 18 Suppl. 2 2002 S10 S15
    • (2002) Diab. Metab. Res. Rev. , vol.18 , pp. S10-S15
    • Hauner, H.1
  • 50
    • 84875462925 scopus 로고    scopus 로고
    • Clinical proof-of-concept study with MSDC-0160, a prototype mTOT-modulating insulin sensitizer
    • J.R. Colca, and et al. Clinical proof-of-concept study with MSDC-0160, a prototype mTOT-modulating insulin sensitizer Clin. Pharmacol. Ther. 93 2013 352 359
    • (2013) Clin. Pharmacol. Ther. , vol.93 , pp. 352-359
    • Colca, J.R.1
  • 51
    • 84875858252 scopus 로고    scopus 로고
    • Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
    • A.S. Divakaruni, and et al. Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier Proc. Natl. Acad. Sci. U.S.A. 110 2013 5422 5427
    • (2013) Proc. Natl. Acad. Sci. U.S.A. , vol.110 , pp. 5422-5427
    • Divakaruni, A.S.1
  • 52
    • 20444497357 scopus 로고    scopus 로고
    • Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
    • D.L. Feinstein, and et al. Receptor-independent actions of PPAR thiazolidinedione agonists: is mitochondrial function the key? Biochem. Pharmacol. 70 2005 177 188
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 177-188
    • Feinstein, D.L.1
  • 53
    • 20944445862 scopus 로고    scopus 로고
    • Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma
    • C. Rousseaux, and et al. Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma J. Exp. Med. 201 2005 1205 1215
    • (2005) J. Exp. Med. , vol.201 , pp. 1205-1215
    • Rousseaux, C.1
  • 54
    • 33747777758 scopus 로고    scopus 로고
    • PPARgamma as a new therapeutic target in inflammatory bowel diseases
    • L. Dubuquoy, and et al. PPARgamma as a new therapeutic target in inflammatory bowel diseases Gut 55 2006 1341 1349
    • (2006) Gut , vol.55 , pp. 1341-1349
    • Dubuquoy, L.1
  • 55
    • 84930221778 scopus 로고    scopus 로고
    • Amorfrutins are natural PPARγ agonists with potent anti-inflammatory properties
    • L. Fuhr, and et al. Amorfrutins are natural PPARγ agonists with potent anti-inflammatory properties J. Nat. Prod. 78 2015 1160 1164
    • (2015) J. Nat. Prod. , vol.78 , pp. 1160-1164
    • Fuhr, L.1
  • 56
    • 81855225795 scopus 로고    scopus 로고
    • Molecular mechanisms of cancer development in obesity
    • M.J. Khandekar, and et al. Molecular mechanisms of cancer development in obesity Nat. Rev. Cancer 11 2011 886 895
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 886-895
    • Khandekar, M.J.1
  • 57
    • 67149146438 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
    • P.D. Home, and et al. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial Lancet 373 2009 2125 2135
    • (2009) Lancet , vol.373 , pp. 2125-2135
    • Home, P.D.1
  • 58
    • 79955427509 scopus 로고    scopus 로고
    • The safety of thiazolidinediones
    • K.G. Tolman The safety of thiazolidinediones Expert Opin. Drug Saf. 10 2011 419 428
    • (2011) Expert Opin. Drug Saf. , vol.10 , pp. 419-428
    • Tolman, K.G.1
  • 59
    • 77954835231 scopus 로고    scopus 로고
    • Planned study of Avandia in doubt after FDA review
    • S. Kean Planned study of Avandia in doubt after FDA review Science 329 2010 375
    • (2010) Science , vol.329 , pp. 375
    • Kean, S.1
  • 60
    • 77957952617 scopus 로고    scopus 로고
    • Regulatory action on rosiglitazone by the U.S. Food and Drug Administration
    • J. Woodcock, and et al. Regulatory action on rosiglitazone by the U.S. Food and Drug Administration N. Engl. J. Med. 363 2010 1489 1491
    • (2010) N. Engl. J. Med. , vol.363 , pp. 1489-1491
    • Woodcock, J.1
  • 61
    • 84890059916 scopus 로고    scopus 로고
    • US regulators relax restrictions on rosiglitazone
    • M. McCarthy US regulators relax restrictions on rosiglitazone BMJ 347 2013 f7144
    • (2013) BMJ , vol.347 , pp. f7144
    • McCarthy, M.1
  • 62
    • 84890931253 scopus 로고    scopus 로고
    • FDA eases restrictions on the glucose-lowering drug rosiglitazone
    • M. Mitka FDA eases restrictions on the glucose-lowering drug rosiglitazone JAMA 310 2013 2604
    • (2013) JAMA , vol.310 , pp. 2604
    • Mitka, M.1
  • 63
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    • S.E. Kahn, and et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy N. Engl. J. Med. 355 2006 2427 2443
    • (2006) N. Engl. J. Med. , vol.355 , pp. 2427-2443
    • Kahn, S.E.1
  • 64
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): A randomised controlled trial
    • J.A. Dormandy, and et al. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial Lancet 366 2005 1279 1289
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1
  • 65
    • 38149077162 scopus 로고    scopus 로고
    • Effect of pioglitazone on cardiovascular outcome in diabetes and chronic kidney disease
    • C.A. Schneider, and et al. Effect of pioglitazone on cardiovascular outcome in diabetes and chronic kidney disease J. Am. Soc. Nephrol. 19 2008 182 187
    • (2008) J. Am. Soc. Nephrol. , vol.19 , pp. 182-187
    • Schneider, C.A.1
  • 66
    • 84860117993 scopus 로고    scopus 로고
    • Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: Retrospective cohort study using UK general practice research database
    • I. Tzoulaki, and et al. Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database BMJ 339 2009 b4731
    • (2009) BMJ , vol.339 , pp. b4731
    • Tzoulaki, I.1
  • 67
    • 50049090547 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on BMD and osteoporosis
    • A.K. McDonough, and et al. The effect of thiazolidinediones on BMD and osteoporosis Nat. Clin. Pract. Endocrinol. Metab. 4 2008 507 513
    • (2008) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 507-513
    • McDonough, A.K.1
  • 68
    • 84883223326 scopus 로고    scopus 로고
    • Comparing pioglitazone to insulin with respect to cancer, cardiovascular and bone fracture endpoints, using propensity score weights
    • C. Vallarino, and et al. Comparing pioglitazone to insulin with respect to cancer, cardiovascular and bone fracture endpoints, using propensity score weights Clin. Drug Invest. 33 2013 621 631
    • (2013) Clin. Drug Invest. , vol.33 , pp. 621-631
    • Vallarino, C.1
  • 69
    • 33747818266 scopus 로고    scopus 로고
    • Nuclear receptors as drug targets in metabolic diseases: New approaches to therapy
    • J.F. Tobin, and L.P. Freedman Nuclear receptors as drug targets in metabolic diseases: new approaches to therapy Trends Endocrinol. Metab. 17 2006 284 290
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 284-290
    • Tobin, J.F.1    Freedman, L.P.2
  • 70
    • 33646045898 scopus 로고    scopus 로고
    • Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases
    • B.L. Balint, and L. Nagy Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases Endocr. Metab. Immune Dis. Drug Targets 6 2006 33 43
    • (2006) Endocr. Metab. Immune Dis. Drug Targets , vol.6 , pp. 33-43
    • Balint, B.L.1    Nagy, L.2
  • 71
    • 77952492038 scopus 로고    scopus 로고
    • Discovery and development of selective PPAR-gamma modulators (SPPAR-gamma Ms) as safe and effective antidiabetic agents
    • L.S. Doshi, and et al. Discovery and development of selective PPAR-gamma modulators (SPPAR-gamma Ms) as safe and effective antidiabetic agents Expert Opin. Invest. Drug 19 2010 489 512
    • (2010) Expert Opin. Invest. Drug , vol.19 , pp. 489-512
    • Doshi, L.S.1
  • 72
    • 84879957850 scopus 로고    scopus 로고
    • Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARgamma) agonist with potent glucose-lowering properties
    • C. Weidner, and et al. Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPARgamma) agonist with potent glucose-lowering properties Diabetologia 56 2013 1802 1812
    • (2013) Diabetologia , vol.56 , pp. 1802-1812
    • Weidner, C.1
  • 73
    • 84921390066 scopus 로고    scopus 로고
    • A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors
    • I.S. Aidhen, and et al. A common building block for the syntheses of amorfrutin and cajaninstilbene acid libraries toward efficient binding with peroxisome proliferator-activated receptors Org. Lett. 17 2015 194 197
    • (2015) Org. Lett. , vol.17 , pp. 194-197
    • Aidhen, I.S.1
  • 74
    • 33644672013 scopus 로고    scopus 로고
    • Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity
    • M. Schupp, and et al. Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity Diabetes 54 2005 3442 3452
    • (2005) Diabetes , vol.54 , pp. 3442-3452
    • Schupp, M.1
  • 75
    • 64249155573 scopus 로고    scopus 로고
    • Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes
    • A. Benardeau, and et al. Aleglitazar, a new, potent, and balanced dual PPARalpha/gamma agonist for the treatment of type II diabetes Bioorg. Med. Chem. Lett. 19 2009 2468 2473
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2468-2473
    • Benardeau, A.1
  • 76
    • 79953203593 scopus 로고    scopus 로고
    • Comparative cardiovascular effects of thiazolidinediones: Systematic review and meta-analysis of observational studies
    • Y.K. Loke, and et al. Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies BMJ 342 2011 d1309
    • (2011) BMJ , vol.342 , pp. d1309
    • Loke, Y.K.1
  • 77
    • 80053131732 scopus 로고    scopus 로고
    • Antidiabetic actions of a non-agonist PPARgamma ligand blocking Cdk5-mediated phosphorylation
    • J.H. Choi, and et al. Antidiabetic actions of a non-agonist PPARgamma ligand blocking Cdk5-mediated phosphorylation Nature 477 2011 477 481
    • (2011) Nature , vol.477 , pp. 477-481
    • Choi, J.H.1
  • 78
    • 84907203364 scopus 로고    scopus 로고
    • A novel non-agonist peroxisome proliferator-activated receptor gamma (PPARgamma) ligand UHC1 blocks PPARgamma phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity
    • S.S. Choi, and et al. A novel non-agonist peroxisome proliferator-activated receptor gamma (PPARgamma) ligand UHC1 blocks PPARgamma phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity J. Biol. Chem. 289 2014 26618 26629
    • (2014) J. Biol. Chem. , vol.289 , pp. 26618-26629
    • Choi, S.S.1
  • 79
    • 84870726015 scopus 로고    scopus 로고
    • Identification of PPARgamma partial agonists of natural origin (I): Development of a virtual screening procedure and in vitro validation
    • L. Guasch, and et al. Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation PLoS ONE 7 2012 e50816
    • (2012) PLoS ONE , vol.7 , pp. e50816
    • Guasch, L.1
  • 80
    • 84928915151 scopus 로고    scopus 로고
    • SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells
    • W. Jiang, and et al. SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells Sci. Rep. 4 2014 7456
    • (2014) Sci. Rep. , vol.4 , pp. 7456
    • Jiang, W.1
  • 81
    • 84908381489 scopus 로고    scopus 로고
    • L312, a novel PPARgamma ligand with potent anti-diabetic activity by selective regulation
    • X. Xie, and et al. L312, a novel PPARgamma ligand with potent anti-diabetic activity by selective regulation Biochim. Biophys. Acta 1850 2015 62 72
    • (2015) Biochim. Biophys. Acta , vol.1850 , pp. 62-72
    • Xie, X.1
  • 82
    • 81055144760 scopus 로고    scopus 로고
    • Adipocyte NCoR knockout decreases PPARgamma phosphorylation and enhances PPARgamma activity and insulin sensitivity
    • P. Li, and et al. Adipocyte NCoR knockout decreases PPARgamma phosphorylation and enhances PPARgamma activity and insulin sensitivity Cell 147 2011 815 826
    • (2011) Cell , vol.147 , pp. 815-826
    • Li, P.1
  • 83
    • 84923124525 scopus 로고    scopus 로고
    • An ERK/Cdk5 axis controls the diabetogenic actions of PPARgamma
    • A.S. Banks, and et al. An ERK/Cdk5 axis controls the diabetogenic actions of PPARgamma Nature 517 2015 391 395
    • (2015) Nature , vol.517 , pp. 391-395
    • Banks, A.S.1
  • 84
    • 84855459760 scopus 로고    scopus 로고
    • Obesity is associated with hypothalamic injury in rodents and humans
    • J.P. Thaler, and et al. Obesity is associated with hypothalamic injury in rodents and humans J. Clin. Invest. 122 2012 153 162
    • (2012) J. Clin. Invest. , vol.122 , pp. 153-162
    • Thaler, J.P.1
  • 85
    • 84890043525 scopus 로고    scopus 로고
    • Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans
    • B. Finan, and et al. Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans Sci. Transl. Med. 5 2013 209ra151
    • (2013) Sci. Transl. Med. , vol.5 , pp. 209ra151
    • Finan, B.1
  • 86
    • 84870902173 scopus 로고    scopus 로고
    • Targeted estrogen delivery reverses the metabolic syndrome
    • B. Finan, and et al. Targeted estrogen delivery reverses the metabolic syndrome Nat. Med. 18 2012 1847 1856
    • (2012) Nat. Med. , vol.18 , pp. 1847-1856
    • Finan, B.1
  • 87
    • 84870896791 scopus 로고    scopus 로고
    • A marriage made to last in drug design
    • M.O. Dietrich, and T.L. Horvath A marriage made to last in drug design Nat. Med. 18 2012 1737 1738
    • (2012) Nat. Med. , vol.18 , pp. 1737-1738
    • Dietrich, M.O.1    Horvath, T.L.2
  • 88
    • 84925282923 scopus 로고    scopus 로고
    • A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
    • B. Finan, and et al. A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents Nat. Med. 21 2015 27 36
    • (2015) Nat. Med. , vol.21 , pp. 27-36
    • Finan, B.1
  • 89
    • 34547863538 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists
    • C. Stahn, and et al. Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists Mol. Cell. Endocrinol. 275 2007 71 78
    • (2007) Mol. Cell. Endocrinol. , vol.275 , pp. 71-78
    • Stahn, C.1
  • 91
    • 83655165300 scopus 로고    scopus 로고
    • Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1
    • A.L. Wu, and et al. Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1 Sci. Transl. Med. 3 2011 113ra126
    • (2011) Sci. Transl. Med. , vol.3 , pp. 113ra126
    • Wu, A.L.1
  • 92
    • 84866462273 scopus 로고    scopus 로고
    • Can noncommunicable diseases be prevented? Lessons from studies of populations and individuals
    • M. Ezzati, and E. Riboli Can noncommunicable diseases be prevented? Lessons from studies of populations and individuals Science 337 2012 1482 1487
    • (2012) Science , vol.337 , pp. 1482-1487
    • Ezzati, M.1    Riboli, E.2
  • 93
    • 84897042175 scopus 로고    scopus 로고
    • Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice
    • C. Weidner, and et al. Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice Mol. Nutr. Food Res. 58 2014 903 907
    • (2014) Mol. Nutr. Food Res. , vol.58 , pp. 903-907
    • Weidner, C.1
  • 94
    • 84893074878 scopus 로고    scopus 로고
    • Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family
    • C. Weidner, and et al. Antidiabetic effects of chamomile flowers extract in obese mice through transcriptional stimulation of nutrient sensors of the peroxisome proliferator-activated receptor (PPAR) family PLoS ONE 8 2013 e80335
    • (2013) PLoS ONE , vol.8 , pp. e80335
    • Weidner, C.1
  • 95
    • 59849116161 scopus 로고    scopus 로고
    • Synergy research: Approaching a new generation of phytopharmaceuticals
    • H. Wagner, and G. Ulrich-Merzenich Synergy research: approaching a new generation of phytopharmaceuticals Phytomedicine 16 2009 97 110
    • (2009) Phytomedicine , vol.16 , pp. 97-110
    • Wagner, H.1    Ulrich-Merzenich, G.2
  • 96
    • 84921812992 scopus 로고    scopus 로고
    • Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes
    • M. Rafraf, and et al. Effectiveness of chamomile tea on glycemic control and serum lipid profile in patients with type 2 diabetes J. Endocrinol. Invest. 38 2015 163 170
    • (2015) J. Endocrinol. Invest. , vol.38 , pp. 163-170
    • Rafraf, M.1
  • 97
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: Using gene-expression signatures to connect small molecules, genes, and disease
    • J. Lamb, and et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease Science 313 2006 1929 1935
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1
  • 98
    • 84880081843 scopus 로고    scopus 로고
    • Protein sets define disease states and predict in vivo effects of drug treatment
    • D. Meierhofer, and et al. Protein sets define disease states and predict in vivo effects of drug treatment Mol. Cell. Proteomics 12 2013 1965 1979
    • (2013) Mol. Cell. Proteomics , vol.12 , pp. 1965-1979
    • Meierhofer, D.1
  • 99
    • 84915820372 scopus 로고    scopus 로고
    • Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs
    • D. Meierhofer, and et al. Integrative analysis of transcriptomics, proteomics, and metabolomics data of white adipose and liver tissue of high-fat diet and rosiglitazone-treated insulin-resistant mice identified pathway alterations and molecular hubs J. Proteome Res. 13 2014 5592 5602
    • (2014) J. Proteome Res. , vol.13 , pp. 5592-5602
    • Meierhofer, D.1
  • 100
    • 84890026795 scopus 로고    scopus 로고
    • Protein set analyses: How could this impact the clinic?
    • S. Sauer Protein set analyses: how could this impact the clinic? Expert Rev. Proteomics 10 2013 305 307
    • (2013) Expert Rev. Proteomics , vol.10 , pp. 305-307
    • Sauer, S.1
  • 101
    • 73249123069 scopus 로고    scopus 로고
    • Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization
    • D.D. Sears, and et al. Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization Proc. Natl. Acad. Sci. U.S.A. 106 2009 18745 18750
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 18745-18750
    • Sears, D.D.1
  • 102
    • 79955692835 scopus 로고    scopus 로고
    • A role for central nervous system PPAR-gamma in the regulation of energy balance
    • K.K. Ryan, and et al. A role for central nervous system PPAR-gamma in the regulation of energy balance Nat. Med. 17 2011 623 626
    • (2011) Nat. Med. , vol.17 , pp. 623-626
    • Ryan, K.K.1
  • 103
    • 79955694276 scopus 로고    scopus 로고
    • Brain PPAR-gamma promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones
    • M. Lu, and et al. Brain PPAR-gamma promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones Nat. Med. 17 2011 618 622
    • (2011) Nat. Med. , vol.17 , pp. 618-622
    • Lu, M.1
  • 104
    • 79955682482 scopus 로고    scopus 로고
    • PPAR-gamma action: It's all in your head
    • M.G. Myers Jr, and C.F. Burant PPAR-gamma action: it's all in your head Nat. Med. 17 2011 544 545
    • (2011) Nat. Med. , vol.17 , pp. 544-545
    • Myers, M.G.1    Burant, C.F.2
  • 106
    • 84891877307 scopus 로고    scopus 로고
    • Regulation of steatohepatitis and PPARgamma signaling by distinct AP-1 dimers
    • S.C. Hasenfuss, and et al. Regulation of steatohepatitis and PPARgamma signaling by distinct AP-1 dimers Cell Metab. 19 2014 84 95
    • (2014) Cell Metab. , vol.19 , pp. 84-95
    • Hasenfuss, S.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.