-
1
-
-
0029862973
-
Hyperinsulinemia as an independent risk factor for ischemic heart disease
-
Despres JP, et al. (1996) Hyperinsulinemia as an independent risk factor for ischemic heart disease. The New Eng J Med 334:952-957.
-
(1996)
The New Eng J Med
, vol.334
, pp. 952-957
-
-
Despres, J.P.1
-
2
-
-
0842277242
-
-
Grundy SM, Brewer HB, Jr, Cleeman JI, Smith SC, Jr, Lenfant C (2004) Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Associa-tion conference on scientific issues related to definition. Circulation 109:433-438.
-
Grundy SM, Brewer HB, Jr, Cleeman JI, Smith SC, Jr, Lenfant C (2004) Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Associa-tion conference on scientific issues related to definition. Circulation 109:433-438.
-
-
-
-
3
-
-
0036224883
-
Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: Relationships to insulin sensitivity, total body fat, and central adiposity
-
Sinha R, et al. (2002) Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: Relationships to insulin sensitivity, total body fat, and central adiposity. Diabetes 51:1022-1027.
-
(2002)
Diabetes
, vol.51
, pp. 1022-1027
-
-
Sinha, R.1
-
4
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS (2006) Inflammation and metabolic disorders. Nature 444:860-867.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
5
-
-
33646572904
-
The metabolic syndrome and adipocytokines
-
Matsuzawa Y (2006) The metabolic syndrome and adipocytokines. FEBS Lett 580:2917-2921.
-
(2006)
FEBS Lett
, vol.580
, pp. 2917-2921
-
-
Matsuzawa, Y.1
-
6
-
-
33748305621
-
Down-regulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha
-
Dahlman I, et al. (2006) Down-regulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha. Diabetes 55:1792-1799.
-
(2006)
Diabetes
, vol.55
, pp. 1792-1799
-
-
Dahlman, I.1
-
7
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, et al. (2003) PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nature Genet 34:267-273.
-
(2003)
Nature Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
-
8
-
-
0033857387
-
Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists
-
Olefsky JM (2000) Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists. J Clin Invest 106:467-472.
-
(2000)
J Clin Invest
, vol.106
, pp. 467-472
-
-
Olefsky, J.M.1
-
9
-
-
34547654459
-
Effect of pioglitazone on atherogenic outcomes in type 2 diabetic patients: A comparison of responders and non-responders
-
Igarashi M, et al. (2007) Effect of pioglitazone on atherogenic outcomes in type 2 diabetic patients: A comparison of responders and non-responders. Diabetes Res Clin Pract 77:389-398.
-
(2007)
Diabetes Res Clin Pract
, vol.77
, pp. 389-398
-
-
Igarashi, M.1
-
10
-
-
0026517631
-
Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects
-
Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM (1992) Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care 15:193-203.
-
(1992)
Diabetes Care
, vol.15
, pp. 193-203
-
-
Suter, S.L.1
Nolan, J.J.2
Wallace, P.3
Gumbiner, B.4
Olefsky, J.M.5
-
11
-
-
0034527587
-
Expression of genes involved in lipid metabolism correlate with peroxisome proliferator-activated receptor gamma expression in human skeletal muscle
-
Lapsys NM, et al. (2000) Expression of genes involved in lipid metabolism correlate with peroxisome proliferator-activated receptor gamma expression in human skeletal muscle. J Clin Endocrinol Metab 85:4293-4297.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 4293-4297
-
-
Lapsys, N.M.1
-
12
-
-
33645863768
-
Transcriptional regulation of metabolism
-
Desvergne B, Michalik L, Wahli W (2006) Transcriptional regulation of metabolism. Physiol Rev 86:465-514.
-
(2006)
Physiol Rev
, vol.86
, pp. 465-514
-
-
Desvergne, B.1
Michalik, L.2
Wahli, W.3
-
13
-
-
0037732481
-
The adipocyte in insulin resistance: Key molecules and the impact of the thiazolidinediones
-
Arner P (2003) The adipocyte in insulin resistance: Key molecules and the impact of the thiazolidinediones. Trends Endocrinol Metab 14:137-145.
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 137-145
-
-
Arner, P.1
-
14
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, et al. (2001) Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98:2005-2010.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
-
15
-
-
33745848775
-
Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony
-
Herman MA,Kahn BB (2006) Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. J Clin Invest 116:1767-1775.
-
(2006)
J Clin Invest
, vol.116
, pp. 1767-1775
-
-
Herman, M.A.1
Kahn, B.B.2
-
16
-
-
23844556589
-
Leptin improves insulin resistance and hyperglycemia in amouse model of type 2 diabetes
-
Toyoshima Y, et al. (2005) Leptin improves insulin resistance and hyperglycemia in amouse model of type 2 diabetes. Endocrinology 146:4024-4035.
-
(2005)
Endocrinology
, vol.146
, pp. 4024-4035
-
-
Toyoshima, Y.1
-
17
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, et al. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
-
18
-
-
23144442351
-
VAMPIRE microarray suite:Aweb-based platform for the interpretation of gene expression data
-
Hsiao A, Ideker T, Olefsky JM, Subramaniam S (2005) VAMPIRE microarray suite:Aweb-based platform for the interpretation of gene expression data. Nucleic Acids Res 33:W627-632.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Hsiao, A.1
Ideker, T.2
Olefsky, J.M.3
Subramaniam, S.4
-
19
-
-
33644874819
-
From genomics to chemical genomics: New developments in KEGG
-
Kanehisa M, et al. (2006) From genomics to chemical genomics: New developments in KEGG. Nucleic Acids Res 34:D354-357.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Kanehisa, M.1
-
20
-
-
33644666743
-
Insulin resistance index as a predictor for pioglitazone treatment in type 2 diabetes
-
Araki T, et al. (2005) Insulin resistance index as a predictor for pioglitazone treatment in type 2 diabetes. Osaka City Med J 51:19-25.
-
(2005)
Osaka City Med J
, vol.51
, pp. 19-25
-
-
Araki, T.1
-
21
-
-
33745458797
-
MondoA-Mlx het-erodimers are candidate sensors of cellular energy status: Mitochondrial localization and direct regulation of glycolysis
-
Sans CL, Satterwhite DJ, Stoltzman CA, Breen KT, Ayer DE (2006) MondoA-Mlx het-erodimers are candidate sensors of cellular energy status: Mitochondrial localization and direct regulation of glycolysis. Mol Cell Biol 26:4863-4871.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4863-4871
-
-
Sans, C.L.1
Satterwhite, D.J.2
Stoltzman, C.A.3
Breen, K.T.4
Ayer, D.E.5
-
22
-
-
39749147110
-
Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
-
Muoio DM, Newgard CB (2008)Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol 9:193-205.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
23
-
-
33749370466
-
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects
-
Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM (2006) Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. Diabetes 55:2277-2285.
-
(2006)
Diabetes
, vol.55
, pp. 2277-2285
-
-
Bandyopadhyay, G.K.1
Yu, J.G.2
Ofrecio, J.3
Olefsky, J.M.4
-
24
-
-
31044447347
-
Inflamed fat: What starts the fire?
-
Neels JG, Olefsky JM (2006) Inflamed fat: What starts the fire? J Clin Invest 116:33-35.
-
(2006)
J Clin Invest
, vol.116
, pp. 33-35
-
-
Neels, J.G.1
Olefsky, J.M.2
-
25
-
-
17844385363
-
Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo
-
Bogacka I, Xie H, Bray GA, Smith SR (2005) Pioglitazone induces mitochondrial biogenesis in human subcutaneous adipose tissue in vivo. Diabetes 54:1392-1399.
-
(2005)
Diabetes
, vol.54
, pp. 1392-1399
-
-
Bogacka, I.1
Xie, H.2
Bray, G.A.3
Smith, S.R.4
-
26
-
-
33644821858
-
Mitochondria are impaired in the adipocytes of type 2 diabetic mice
-
Choo HJ, et al. (2006) Mitochondria are impaired in the adipocytes of type 2 diabetic mice. Diabetologia 49:784-791.
-
(2006)
Diabetologia
, vol.49
, pp. 784-791
-
-
Choo, H.J.1
-
27
-
-
34347391646
-
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone
-
Rong JX, et al. (2007) Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone. Diabetes 56:1751-1760.
-
(2007)
Diabetes
, vol.56
, pp. 1751-1760
-
-
Rong, J.X.1
-
28
-
-
85047689659
-
Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone
-
Wilson-Fritch L, et al. (2004) Mitochondrial remodeling in adipose tissue associated with obesity and treatment with rosiglitazone. J Clin Invest 114:1281-1289.
-
(2004)
J Clin Invest
, vol.114
, pp. 1281-1289
-
-
Wilson-Fritch, L.1
-
29
-
-
0036789137
-
The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
-
Yu JG, et al. (2002)The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2968-2974.
-
(2002)
Diabetes
, vol.51
, pp. 2968-2974
-
-
Yu, J.G.1
-
30
-
-
0033980466
-
Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects
-
Frias JP,Yu JG, Kruszynska YT, Olefsky JM(2000) Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects. Diabetes Care 23:64-69.
-
(2000)
Diabetes Care
, vol.23
, pp. 64-69
-
-
Frias, J.P.1
Yu, J.G.2
Kruszynska, Y.T.3
Olefsky, J.M.4
-
31
-
-
0000648085
-
Influences of glucose loading and of injected insulin on hepatic glucose output
-
Steele R (1959) Influences of glucose loading and of injected insulin on hepatic glucose output. Ann N Y Acad Sci 82:420-430.
-
(1959)
Ann N Y Acad Sci
, vol.82
, pp. 420-430
-
-
Steele, R.1
-
32
-
-
0021311455
-
Tracers in metabolic research: Radioisotope and stable isotope/mass spectrometry methods
-
Wolfe RR (1984) Tracers in metabolic research: Radioisotope and stable isotope/mass spectrometry methods. Lab Res Methods Biol Med 9:1-287.
-
(1984)
Lab Res Methods Biol Med
, vol.9
, pp. 1-287
-
-
Wolfe, R.R.1
-
33
-
-
0015146643
-
Use of polyethylene glycol to separate free and anti-body-bound peptide hormones in radioimmunoassays
-
Desbuquois B, Aurbach GD (1971) Use of polyethylene glycol to separate free and anti-body-bound peptide hormones in radioimmunoassays. J Clin Endocrinol Metab 33:732-738.
-
(1971)
J Clin Endocrinol Metab
, vol.33
, pp. 732-738
-
-
Desbuquois, B.1
Aurbach, G.D.2
-
34
-
-
10244251720
-
Variance-modeled posterior inference of microarray data: Detecting gene-expression changes in 3T3-L1 adipocytes
-
Hsiao A, Worrall DS, Olefsky JM, Subramaniam S (2004) Variance-modeled posterior inference of microarray data: Detecting gene-expression changes in 3T3-L1 adipocytes. Bioinformatics 20:3108-3127.
-
(2004)
Bioinformatics
, vol.20
, pp. 3108-3127
-
-
Hsiao, A.1
Worrall, D.S.2
Olefsky, J.M.3
Subramaniam, S.4
-
35
-
-
0004285343
-
-
McGraw-Hill Medical Pub Division, New York 6th Ed, p
-
Glantz SA (2005) Primer of Biostatistics (McGraw-Hill Medical Pub Division, New York) 6th Ed, p 520.
-
(2005)
Primer of Biostatistics
, pp. 520
-
-
Glantz, S.A.1
|