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Volumn 417, Issue 4, 2012, Pages 1158-1163

O-GlcNAc modification of PPARγ reduces its transcriptional activity

Author keywords

3T3 L1; Adipogenesis; O GlcNAc; PPAR

Indexed keywords

N ACETYLGLUCOSAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; THREONINE;

EID: 84862777029     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.12.086     Document Type: Article
Times cited : (69)

References (35)
  • 1
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., Heyman R.A., Evans R.M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 1992, 358:771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 2
    • 0030771852 scopus 로고    scopus 로고
    • DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region
    • Juge-Aubry C., Pernin A., Favez T., Burger A.G., Wahli W., Meier C.A., Desvergne B. DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region. J. Biol. Chem. 1997, 272:25252-25259.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25252-25259
    • Juge-Aubry, C.1    Pernin, A.2    Favez, T.3    Burger, A.G.4    Wahli, W.5    Meier, C.A.6    Desvergne, B.7
  • 3
    • 3242784885 scopus 로고    scopus 로고
    • Mechanism of the nuclear receptor molecular switch
    • Nagy L., Schwabe J.W. Mechanism of the nuclear receptor molecular switch. Trends Biochem. Sci. 2004, 29:317-324.
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 317-324
    • Nagy, L.1    Schwabe, J.W.2
  • 5
    • 0033583023 scopus 로고    scopus 로고
    • P300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively
    • Gelman L., Zhou G., Fajas L., Raspe E., Fruchart J.C., Auwerx J. P300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively. J. Biol. Chem. 1999, 274:7681-7688.
    • (1999) J. Biol. Chem. , vol.274 , pp. 7681-7688
    • Gelman, L.1    Zhou, G.2    Fajas, L.3    Raspe, E.4    Fruchart, J.C.5    Auwerx, J.6
  • 6
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O., Foufelle F., Scotto C., Dauca M., Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 1996, 137:354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 7
    • 33748942837 scopus 로고    scopus 로고
    • Transcriptional control of adipocyte formation
    • Farmer S.R. Transcriptional control of adipocyte formation. Cell Metab. 2006, 4:263-273.
    • (2006) Cell Metab. , vol.4 , pp. 263-273
    • Farmer, S.R.1
  • 9
    • 0034892766 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis
    • Fajas L., Debril M.B., Auwerx J. Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis. J. Mol. Endocrinol. 2001, 27:1-9.
    • (2001) J. Mol. Endocrinol. , vol.27 , pp. 1-9
    • Fajas, L.1    Debril, M.B.2    Auwerx, J.3
  • 10
    • 3042613480 scopus 로고    scopus 로고
    • O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
    • Zachara N.E., Hart G.W. O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochim. Biophys. Acta 2004, 1673:13-28.
    • (2004) Biochim. Biophys. Acta , vol.1673 , pp. 13-28
    • Zachara, N.E.1    Hart, G.W.2
  • 11
    • 34247583996 scopus 로고    scopus 로고
    • Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins
    • Hart G.W., Housley M.P., Slawson C. Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins. Nature 2007, 446:1017-1022.
    • (2007) Nature , vol.446 , pp. 1017-1022
    • Hart, G.W.1    Housley, M.P.2    Slawson, C.3
  • 12
    • 33644874204 scopus 로고    scopus 로고
    • The hexosamine signaling pathway: deciphering the " O-GlcNAc code"
    • Love D.C., Hanover J.A. The hexosamine signaling pathway: deciphering the " O-GlcNAc code" Sci. STKE 2005, 2005:re13.
    • (2005) Sci. STKE , vol.2005
    • Love, D.C.1    Hanover, J.A.2
  • 13
    • 0037300799 scopus 로고    scopus 로고
    • A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance
    • Wells L., Vosseller K., Hart G.W. A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance. Cell. Mol. Life Sci. 2003, 60:222-228.
    • (2003) Cell. Mol. Life Sci. , vol.60 , pp. 222-228
    • Wells, L.1    Vosseller, K.2    Hart, G.W.3
  • 15
    • 33747081065 scopus 로고    scopus 로고
    • Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, Metabolism, and dauer
    • Forsythe M.E., Love D.C., Lazarus B.D., Kim E.J., Prinz W.A., Ashwell G., Krause M.W., Hanover J.A. Caenorhabditis elegans ortholog of a diabetes susceptibility locus: oga-1 (O-GlcNAcase) knockout impacts O-GlcNAc cycling, Metabolism, and dauer. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:11952-11957.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 11952-11957
    • Forsythe, M.E.1    Love, D.C.2    Lazarus, B.D.3    Kim, E.J.4    Prinz, W.A.5    Ashwell, G.6    Krause, M.W.7    Hanover, J.A.8
  • 16
    • 1942456595 scopus 로고    scopus 로고
    • Sequential gene promoter interactions by C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis
    • Tang Q.Q., Zhang J.W., Daniel Lane M. Sequential gene promoter interactions by C/EBPbeta, C/EBPalpha, and PPARgamma during adipogenesis. Biochem. Biophys. Res. Commun. 2004, 318:213-218.
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 213-218
    • Tang, Q.Q.1    Zhang, J.W.2    Daniel Lane, M.3
  • 17
  • 18
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene
    • Tugwood J.D., Issemann I., Anderson R.G., Bundell K.R., McPheat W.L., Green S. The mouse peroxisome proliferator activated receptor recognizes a response element in the 5' flanking sequence of the rat acyl CoA oxidase gene. EMBO J. 1992, 11:433-439.
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 20
    • 33749160125 scopus 로고    scopus 로고
    • Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability
    • Yang W.H., Kim J.E., Nam H.W., Ju J.W., Kim H.S., Kim Y.S., Cho J.W. Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability. Nat. Cell Biol. 2006, 8:1074-1083.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1074-1083
    • Yang, W.H.1    Kim, J.E.2    Nam, H.W.3    Ju, J.W.4    Kim, H.S.5    Kim, Y.S.6    Cho, J.W.7
  • 21
    • 77955270120 scopus 로고    scopus 로고
    • Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation
    • Ishihara K., Takahashi I., Tsuchiya Y., Hasegawa M., Kamemura K. Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation. Biochem. Biophys. Res. Commun. 2010, 398:489-494.
    • (2010) Biochem. Biophys. Res. Commun. , vol.398 , pp. 489-494
    • Ishihara, K.1    Takahashi, I.2    Tsuchiya, Y.3    Hasegawa, M.4    Kamemura, K.5
  • 22
    • 80054911289 scopus 로고    scopus 로고
    • Suppression of Glutamine: fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes
    • Hsieh T.-J., Lin T., Hsieh P.-C., Liao M.-C., Shin S.-J. Suppression of Glutamine: fructose-6-phosphate amidotransferase-1 inhibits adipogenesis in 3T3-L1 adipocytes. J. Cell. Physiol. 2012, 227:108-115.
    • (2012) J. Cell. Physiol. , vol.227 , pp. 108-115
    • Hsieh, T.-J.1    Lin, T.2    Hsieh, P.-C.3    Liao, M.-C.4    Shin, S.-J.5
  • 23
    • 1642378571 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes
    • Arimura N., Horiba T., Imagawa M., Shimizu M., Sato R. The peroxisome proliferator-activated receptor gamma regulates expression of the perilipin gene in adipocytes. J. Biol. Chem. 2004, 279:10070-10076.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10070-10076
    • Arimura, N.1    Horiba, T.2    Imagawa, M.3    Shimizu, M.4    Sato, R.5
  • 24
    • 33744497272 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis
    • Hummasti S., Tontonoz P. The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis. Mol. Endocrinol. 2006, 20:1261-1275.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 1261-1275
    • Hummasti, S.1    Tontonoz, P.2
  • 25
    • 66449119706 scopus 로고    scopus 로고
    • The PPARgamma2 A/B-domain plays a gene-specific role in transactivation and cofactor recruitment
    • Bugge A., Grontved L., Aagaard M.M., Borup R., Mandrup S. The PPARgamma2 A/B-domain plays a gene-specific role in transactivation and cofactor recruitment. Mol. Endocrinol. 2009, 23:794-808.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 794-808
    • Bugge, A.1    Grontved, L.2    Aagaard, M.M.3    Borup, R.4    Mandrup, S.5
  • 26
    • 0034669882 scopus 로고    scopus 로고
    • Why are " natively unfolded" proteins unstructured under physiologic conditions?
    • Uversky V.N., Gillespie J.R., Fink A.L. Why are " natively unfolded" proteins unstructured under physiologic conditions?. Proteins 2000, 41:415-427.
    • (2000) Proteins , vol.41 , pp. 415-427
    • Uversky, V.N.1    Gillespie, J.R.2    Fink, A.L.3
  • 27
    • 0029662315 scopus 로고    scopus 로고
    • Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity
    • Kriwacki R.W., Hengst L., Tennant L., Reed S.I., Wright P.E. Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:11504-11509.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 11504-11509
    • Kriwacki, R.W.1    Hengst, L.2    Tennant, L.3    Reed, S.I.4    Wright, P.E.5
  • 30
    • 67049158217 scopus 로고    scopus 로고
    • Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides
    • Chalkley R.J., Thalhammer A., Schoepfer R., Burlingame A.L. Identification of protein O-GlcNAcylation sites using electron transfer dissociation mass spectrometry on native peptides. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:8894-8899.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 8894-8899
    • Chalkley, R.J.1    Thalhammer, A.2    Schoepfer, R.3    Burlingame, A.L.4
  • 32
    • 79961138782 scopus 로고    scopus 로고
    • A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome
    • Keembiyehetty C.N., Krzeslak A., Love D.C., Hanover J.A. A lipid-droplet-targeted O-GlcNAcase isoform is a key regulator of the proteasome. J. Cell Sci. 2011, 124:2851-2860.
    • (2011) J. Cell Sci. , vol.124 , pp. 2851-2860
    • Keembiyehetty, C.N.1    Krzeslak, A.2    Love, D.C.3    Hanover, J.A.4
  • 33
    • 33646354409 scopus 로고    scopus 로고
    • Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter
    • Zuo Y., Qiang L., Farmer S.R. Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter. J. Biol. Chem. 2006, 281:7960-7967.
    • (2006) J. Biol. Chem. , vol.281 , pp. 7960-7967
    • Zuo, Y.1    Qiang, L.2    Farmer, S.R.3
  • 34
    • 36649015243 scopus 로고    scopus 로고
    • Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis
    • Brasaemle D.L. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid Res. 2007, 48:2547-2559.
    • (2007) J. Lipid Res. , vol.48 , pp. 2547-2559
    • Brasaemle, D.L.1
  • 35
    • 0021150273 scopus 로고
    • Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxo-L-norleucine or 2-deoxy-D-glucose
    • Goldstein G., Guskey L.E. Poliovirus and vesicular stomatitis virus replication in the presence of 6-diazo-5-oxo-L-norleucine or 2-deoxy-D-glucose. J. Med. Virol. 1984, 14:159-167.
    • (1984) J. Med. Virol. , vol.14 , pp. 159-167
    • Goldstein, G.1    Guskey, L.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.