-
1
-
-
34250803204
-
Epidemiology of chronic musculoskeletal pain
-
McBeth, J. & Jones, K. Epidemiology of chronic musculoskeletal pain. Best Pract Res Clin Rheumatol 21, 403-425, doi:10.1016/j.berh.2007.03.003 (2007).
-
(2007)
Best Pract Res Clin Rheumatol
, vol.21
, pp. 403-425
-
-
McBeth, J.1
Jones, K.2
-
2
-
-
84863478238
-
Low back pain: Epidemiology of consultations
-
Joud, A., Petersson, I. F. & Englund, M. Low back pain: epidemiology of consultations. Arthritis Care Res 64, 1084-1088, doi:10.1002/acr.21642 (2012).
-
(2012)
Arthritis Care Res
, vol.64
, pp. 1084-1088
-
-
Joud, A.1
Petersson, I.F.2
Englund, M.3
-
3
-
-
0033996519
-
Anterior lumbar fusion improves discogenic pain at levels of prior posterolateral fusion
-
Barrick, W. T. et al. Anterior lumbar fusion improves discogenic pain at levels of prior posterolateral fusion. Spine 25, 853-857 (2000).
-
(2000)
Spine
, vol.25
, pp. 853-857
-
-
Barrick, W.T.1
-
4
-
-
0017336286
-
The anatomical source of back pain
-
Kellgren, J. H. The anatomical source of back pain. Rheumatol Rehabil 16, 3-12 (1977).
-
(1977)
Rheumatol Rehabil
, vol.16
, pp. 3-12
-
-
Kellgren, J.H.1
-
5
-
-
0025853545
-
The tissue origin of low back pain and sciatica: A report of pain response to tissue stimulation during operations on the lumbar spine using local anesthesia
-
Kuslich, S. D., Ulstrom, C. L. & Michael, C. J. The tissue origin of low back pain and sciatica: a report of pain response to tissue stimulation during operations on the lumbar spine using local anesthesia. Orthop Clin North Am 22, 181-187 (1991).
-
(1991)
Orthop Clin North Am
, vol.22
, pp. 181-187
-
-
Kuslich, S.D.1
Ulstrom, C.L.2
Michael, C.J.3
-
6
-
-
0342514575
-
Low back pain in relation to lumbar disc degeneration
-
Luoma, K. et al. Low back pain in relation to lumbar disc degeneration. Spine 25, 487-492 (2000).
-
(2000)
Spine
, vol.25
, pp. 487-492
-
-
Luoma, K.1
-
7
-
-
0032055960
-
Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls
-
Gruber, H. E. & Hanley, E. N., Jr. Analysis of aging and degeneration of the human intervertebral disc. Comparison of surgical specimens with normal controls. Spine 23, 751-757 (1998).
-
(1998)
Spine
, vol.23
, pp. 751-757
-
-
Gruber, H.E.1
Hanley, E.N.2
-
8
-
-
0346847531
-
Biologic strategies for the therapy of intervertebral disc degeneration
-
Gruber, H. E. & Hanley, E. N., Jr. Biologic strategies for the therapy of intervertebral disc degeneration. Expert Opin Biol Ther 3, 1209-1214, doi:10.1517/14712598.3.8.1209 (2003).
-
(2003)
Expert Opin Biol Ther
, vol.3
, pp. 1209-1214
-
-
Gruber, H.E.1
Hanley, E.N.2
-
9
-
-
0035868674
-
Expression of Fas ligand and apoptosis of disc cells in herniated lumbar disc tissue
-
Park, J. B., Chang, H. & Kim, K.W. Expression of Fas ligand and apoptosis of disc cells in herniated lumbar disc tissue. Spine 26, 618-621 (2001).
-
(2001)
Spine
, vol.26
, pp. 618-621
-
-
Park, J.B.1
Chang, H.2
Kim, K.W.3
-
10
-
-
0035863571
-
Expression of Fas receptor on disc cells in herniated lumbar disc tissue
-
Park, J. B., Kim, K.W., Han, C. W. & Chang, H. Expression of Fas receptor on disc cells in herniated lumbar disc tissue. Spine 26, 142-146 (2001).
-
(2001)
Spine
, vol.26
, pp. 142-146
-
-
Park, J.B.1
Kim, K.W.2
Han, C.W.3
Chang, H.4
-
11
-
-
33845360165
-
Programmed cell death in intervertebral disc degeneration
-
Zhao, C. Q., Jiang, L. S. & Dai, L. Y. Programmed cell death in intervertebral disc degeneration. Apoptosis 11, 2079-2088, doi:10.1007/s10495-006-0290-7 (2006).
-
(2006)
Apoptosis
, vol.11
, pp. 2079-2088
-
-
Zhao, C.Q.1
Jiang, L.S.2
Dai, L.Y.3
-
12
-
-
34548620230
-
The cell biology of intervertebral disc aging and degeneration
-
Zhao, C. Q., Wang, L. M., Jiang, L. S. & Dai, L. Y. The cell biology of intervertebral disc aging and degeneration. Ageing Res Rev 6, 247-261, doi:10.1016/ j.arr.2007.08.001 (2007).
-
(2007)
Ageing Res Rev
, vol.6
, pp. 247-261
-
-
Zhao, C.Q.1
Wang, L.M.2
Jiang, L.S.3
Dai, L.Y.4
-
13
-
-
13944253348
-
Calorie restriction--the SIR2 connection
-
Guarente, L. & Picard, F. Calorie restriction--the SIR2 connection. Cell 120, 473-482, doi:10.1016/j.cell.2005.01.029 (2005).
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
14
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen, H. Y. et al. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (New York, N.Y.) 305, 390-392, doi:10.1126/science.1099196 (2004).
-
(2004)
Science (New York, N.Y.)
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
-
15
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
Saunders, L. R. & Verdin, E. Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene 26, 5489-5504, doi:10.1038/sj.onc.1210616 (2007).
-
(2007)
Oncogene
, vol.26
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
16
-
-
84892581395
-
SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway
-
Wang, D. et al. SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway. Age (Dordrecht, Netherlands) 35, 1741-1753, doi:10.1007/s11357-012-9474-y (2013).
-
(2013)
Age (Dordrecht, Netherlands)
, vol.35
, pp. 1741-1753
-
-
Wang, D.1
-
17
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
Shintani, T. & Klionsky, D. J. Autophagy in health and disease: a double-edged sword. Science (New York, N.Y.) 306, 990-995, doi:10.1126/science.1099993 (2004).
-
(2004)
Science (New York, N.Y.)
, vol.306
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
18
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
Yang, Z. & Klionsky, D. J. Eaten alive: a history of macroautophagy. Nat Cell Biol 12, 814-822, doi:10.1038/ncb0910-814 (2010).
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
19
-
-
38049115875
-
Apoptosis and autophagy: Regulatory connections between two supposedly different processes
-
Thorburn, A. Apoptosis and autophagy: regulatory connections between two supposedly different processes. Apoptosis 13, 1-9, doi:10.1007/s10495-007-0154- 9 (2008).
-
(2008)
Apoptosis
, vol.13
, pp. 1-9
-
-
Thorburn, A.1
-
20
-
-
80755188000
-
Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus
-
Ye, W. et al. Age-related increases of macroautophagy and chaperone-mediated autophagy in rat nucleus pulposus. Connect Tissue Res 52, 472-478, doi:10.3109/ 03008207.2011.564336 (2011).
-
(2011)
Connect Tissue Res
, vol.52
, pp. 472-478
-
-
Ye, W.1
-
21
-
-
84872133973
-
Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats
-
Ye, W. et al. Increased macroautophagy in the pathological process of intervertebral disc degeneration in rats. Connect Tissue Res 54, 22-28, doi:10.3109/03008207.2012.715702 (2013).
-
(2013)
Connect Tissue Res
, vol.54
, pp. 22-28
-
-
Ye, W.1
-
22
-
-
38649097225
-
Are animal models useful for studying human disc disorders/ degeneration?
-
Alini, M. et al. Are animal models useful for studying human disc disorders/ degeneration? Eur Spine J 17, 2-19, doi:10.1007/s00586-007-0414-y (2008).
-
(2008)
Eur Spine J
, vol.17
, pp. 2-19
-
-
Alini, M.1
-
23
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
Ravikumar, B. et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 90, 1383-1435, doi:10.1152/physrev.00030.2009 (2010).
-
(2010)
Physiol Rev
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
-
24
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell 132, 27-42, doi:10.1016/j.cell.2007.12.018 (2008).
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
25
-
-
77649128750
-
Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis
-
Carames, B., Taniguchi, N., Otsuki, S., Blanco, F. J. & Lotz, M. Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. Arthritis Rheum 62, 791-801, doi:10.1002/art.27305 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 791-801
-
-
Carames, B.1
Taniguchi, N.2
Otsuki, S.3
Blanco, F.J.4
Lotz, M.5
-
26
-
-
0028544616
-
The age-related characteristics of autophagocytosis in different tissues of laboratory animals
-
Stupina, A. S., Terman, A. K., Kvitnitskaia-Ryzhova, T., Mezhiborskaia, N. A. & Zherebitskii, V. A. The age-related characteristics of autophagocytosis in different tissues of laboratory animals. Tsitol Genet 28, 15-20 (1994).
-
(1994)
Tsitol Genet
, vol.28
, pp. 15-20
-
-
Stupina, A.S.1
Terman, A.K.2
Kvitnitskaia-Ryzhova, T.3
Mezhiborskaia, N.A.4
Zherebitskii, V.A.5
-
27
-
-
77955342581
-
Inhibition of autophagy in the heart induces age-related cardiomyopathy
-
Taneike, M. et al. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6, 600-606, doi:10.4161/auto.6.5.11947 (2010).
-
(2010)
Autophagy
, vol.6
, pp. 600-606
-
-
Taneike, M.1
-
28
-
-
10344267546
-
Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: A species comparison
-
Hunter, C. J., Matyas, J. R. & Duncan, N. A. Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison. J Anat 205, 357-362, doi:10.1111/j.0021-8782.2004.00352.x (2004).
-
(2004)
J Anat
, vol.205
, pp. 357-362
-
-
Hunter, C.J.1
Matyas, J.R.2
Duncan, N.A.3
-
29
-
-
84902876728
-
Differential expression of extracellular-signal-regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells
-
Liang, W. et al. Differential expression of extracellular-signal-regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells. Biochem Biophys Res Commun 449, 466-470, doi:10.1016/j.bbrc.2014.05.042 (2014).
-
(2014)
Biochem Biophys Res Commun
, vol.449
, pp. 466-470
-
-
Liang, W.1
-
30
-
-
84892991169
-
The evidence and the possible significance of autophagy in degeneration model of human cervical end-plate cartilage
-
Xu, H., Xiong, S., Wang, H., Zhang, M. & Yu, Y. The evidence and the possible significance of autophagy in degeneration model of human cervical end-plate cartilage. Exp Ther Med 7, 537-542, doi:10.3892/etm.2013.1465 (2014).
-
(2014)
Exp Ther Med
, vol.7
, pp. 537-542
-
-
Xu, H.1
Xiong, S.2
Wang, H.3
Zhang, M.4
Yu, Y.5
-
31
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor, R. R. et al. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circulation research 100, 1512-1521, doi:10.1161/ 01.RES.0000267723.65696.4a (2007).
-
(2007)
Circulation Research
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
-
32
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki, T., Sasaki, Y. & Milbrandt, J. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science (New York, N.Y.) 305, 1010-1013, doi:10.1126/science.1098014 (2004).
-
(2004)
Science (New York, N.Y.)
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
33
-
-
77951717549
-
SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway
-
Gagarina, V. et al. SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway. Arthritis Rheum 62, 1383-1392, doi:10.1002/ art.27369 (2010).
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1383-1392
-
-
Gagarina, V.1
-
34
-
-
69449107308
-
SIRT1 regulation of apoptosis of human chondrocytes
-
Takayama, K. et al. SIRT1 regulation of apoptosis of human chondrocytes. Arthritis Rheum 60, 2731-2740, doi:10.1002/art.24864 (2009).
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2731-2740
-
-
Takayama, K.1
-
35
-
-
84887346480
-
Resveratrol protects HUVECs from oxidized-LDL induced oxidative damage by autophagy upregulation via the AMPK/SIRT1 pathway
-
Guo, H., Chen, Y., Liao, L. & Wu, W. Resveratrol protects HUVECs from oxidized-LDL induced oxidative damage by autophagy upregulation via the AMPK/SIRT1 pathway. Cardiovasc Drugs Ther 27, 189-198, doi:10.1007/s10557- 013-6442-4 (2013).
-
(2013)
Cardiovasc Drugs Ther
, vol.27
, pp. 189-198
-
-
Guo, H.1
Chen, Y.2
Liao, L.3
Wu, W.4
-
36
-
-
41549138483
-
Arole for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
Lee, I. H. et al. Arole for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A 105, 3374-3379, doi:10.1073/ pnas.0712145105 (2008).
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
-
37
-
-
84898031861
-
SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress
-
Ou, X., Lee, M. R., Huang, X., Messina-Graham, S. & Broxmeyer, H. E. SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress. Stem cells (Dayton, Ohio) 32, 1183-1194, doi:10.1002/ stem.1641 (2014).
-
(2014)
Stem Cells (Dayton, Ohio)
, vol.32
, pp. 1183-1194
-
-
Ou, X.1
Lee, M.R.2
Huang, X.3
Messina-Graham, S.4
Broxmeyer, H.E.5
-
38
-
-
84855468411
-
Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1
-
Zeng, R., Chen, Y., Zhao, S. & Cui, G. H. Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1. Acta Pharmacol Sin 33, 91-100, doi:10.1038/ aps.2011.143 (2012).
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 91-100
-
-
Zeng, R.1
Chen, Y.2
Zhao, S.3
Cui, G.H.4
-
39
-
-
84908478414
-
ER stress-mediated autophagy protects against LPS-induced apoptosis in HL-1 cardiomyocytes
-
Zou, X. et al. ER stress-mediated autophagy protects against LPS-induced apoptosis in HL-1 cardiomyocytes. Exp Physiol 99, 1348-1358, doi:10.1113/ expphysiol.2014.079012 (2014).
-
(2014)
Exp Physiol
, vol.99
, pp. 1348-1358
-
-
Zou, X.1
-
40
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
-
41
-
-
84886410536
-
Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway
-
Yang, Y. H. et al. Estradiol inhibits osteoblast apoptosis via promotion of autophagy through the ER-ERK-mTOR pathway. Apoptosis 18, 1363-1375, doi:10.1007/s10495-013-0867-x (2013).
-
(2013)
Apoptosis
, vol.18
, pp. 1363-1375
-
-
Yang, Y.H.1
-
42
-
-
84868139191
-
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
-
Jeong, J. K., Moon, M.H., Lee, Y. J., Seol, J. W. & Park, S. Y. Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity. Neurobiol Aging 34, 146-156, doi:10.1016/j.neurobiolaging.2012.04.002 (2013).
-
(2013)
Neurobiol Aging
, vol.34
, pp. 146-156
-
-
Jeong, J.K.1
Moon, M.H.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
43
-
-
84912558699
-
Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice
-
Wang, B. et al. Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice. J Cell MolMed 18, 1599-1611, doi:10.1111/ jcmm.12312 (2014).
-
(2014)
J Cell MolMed
, vol.18
, pp. 1599-1611
-
-
Wang, B.1
-
44
-
-
84893849787
-
Enhancement in efferocytosis of oxidized low-density lipoprotein-induced apoptotic RAW264.7 cells through Sirt1- mediated autophagy
-
Liu, B., Zhang, B., Guo, R., Li, S. & Xu, Y. Enhancement in efferocytosis of oxidized low-density lipoprotein-induced apoptotic RAW264.7 cells through Sirt1- mediated autophagy. Int J Mol Med 33, 523-533, doi:10.3892/ijmm.2013.1609 (2014).
-
(2014)
Int J Mol Med
, vol.33
, pp. 523-533
-
-
Liu, B.1
Zhang, B.2
Guo, R.3
Li, S.4
Xu, Y.5
-
45
-
-
84882935541
-
Sirtuins' modulation of autophagy
-
Ng, F. & Tang, B. L. Sirtuins' modulation of autophagy. J Cell Physiol 228, 2262-2270, doi:10.1002/jcp.24399 (2013).
-
(2013)
J Cell Physiol
, vol.228
, pp. 2262-2270
-
-
Ng, F.1
Tang, B.L.2
-
46
-
-
67349273985
-
SIRT1: Regulation of longevity via autophagy
-
Salminen, A. & Kaarniranta, K. SIRT1: regulation of longevity via autophagy. Cell Signal 21, 1356-1360, doi:10.1016/j.cellsig.2009.02.014 (2009).
-
(2009)
Cell Signal
, vol.21
, pp. 1356-1360
-
-
Salminen, A.1
Kaarniranta, K.2
-
47
-
-
79959626436
-
Autophagy and apoptosis: What is the connection?
-
Gump, J. M. & Thorburn, A. Autophagy and apoptosis: what is the connection? Trends Cell Biol 21, 387-392, doi:10.1016/j.tcb.2011.03.007 (2011).
-
(2011)
Trends Cell Biol
, vol.21
, pp. 387-392
-
-
Gump, J.M.1
Thorburn, A.2
-
48
-
-
84873546725
-
Life in the balance - A mechanistic view of the crosstalk between autophagy and apoptosis
-
Rubinstein, A. D. & Kimchi, A. Life in the balance - a mechanistic view of the crosstalk between autophagy and apoptosis. J Cell Sci 125, 5259-5268, doi:10.1242/jcs.115865 (2012).
-
(2012)
J Cell Sci
, vol.125
, pp. 5259-5268
-
-
Rubinstein, A.D.1
Kimchi, A.2
-
49
-
-
0035449038
-
Magnetic resonance classification of lumbar intervertebral disc degeneration
-
Pfirrmann, C. W., Metzdorf, A., Zanetti, M., Hodler, J. & Boos, N. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine 26, 1873-1878 (2001).
-
(2001)
Spine
, vol.26
, pp. 1873-1878
-
-
Pfirrmann, C.W.1
Metzdorf, A.2
Zanetti, M.3
Hodler, J.4
Boos, N.5
|