메뉴 건너뛰기




Volumn , Issue , 2003, Pages 837-860

Tumor necrosis factor

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84942923820     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012689663-3/50039-9     Document Type: Chapter
Times cited : (65)

References (253)
  • 1
    • 8244235133 scopus 로고    scopus 로고
    • P55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. Ro 45-2081 Study Group
    • Abraham E., Glauser M.P., Butler T., et al. p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. Ro 45-2081 Study Group. JAMA 1997, 277:1531-1538.
    • (1997) JAMA , vol.277 , pp. 1531-1538
    • Abraham, E.1    Glauser, M.P.2    Butler, T.3
  • 2
    • 0032495658 scopus 로고    scopus 로고
    • Doubleblind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock NORASEPT II Study Group
    • Abraham E., Anzueto A., Gutierrez G., et al. Doubleblind randomised controlled trial of monoclonal antibody to human tumour necrosis factor in treatment of septic shock NORASEPT II Study Group. Lancet 1998, 351:929-933.
    • (1998) Lancet , vol.351 , pp. 929-933
    • Abraham, E.1    Anzueto, A.2    Gutierrez, G.3
  • 3
    • 0027399029 scopus 로고
    • Polymorphic MHC ancestral haplotypes affect the activity of tumour necrosis factor-a
    • Abraham L.J., French M.A., Dawkins R.L. Polymorphic MHC ancestral haplotypes affect the activity of tumour necrosis factor-a. Clin. Exp. Immunol. 1993, 92:14-18.
    • (1993) Clin. Exp. Immunol. , vol.92 , pp. 14-18
    • Abraham, L.J.1    French, M.A.2    Dawkins, R.L.3
  • 4
    • 0030595340 scopus 로고    scopus 로고
    • FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
    • Adam-Klages S., Adam D., Wiegmann K., et al. FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 1996, 86:937-947.
    • (1996) Cell , vol.86 , pp. 937-947
    • Adam-Klages, S.1    Adam, D.2    Wiegmann, K.3
  • 5
    • 0030265258 scopus 로고    scopus 로고
    • The potential biological and clinical significance of the soluble tumor necrosis factor receptors
    • Aderka D. The potential biological and clinical significance of the soluble tumor necrosis factor receptors. Cytokine Growth Factor Rev. 1996, 7:231-240.
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 231-240
    • Aderka, D.1
  • 6
    • 0027366455 scopus 로고
    • Major histocompatibility complex susceptibility genes for dermatitis herpetiformis compared with those for glutensensitive enteropathy
    • Ahmed A.R., Yunis J.J., Marcus-Bagley D., et al. Major histocompatibility complex susceptibility genes for dermatitis herpetiformis compared with those for glutensensitive enteropathy. J. Exp. Med. 1993, 178:2067-2075.
    • (1993) J. Exp. Med. , vol.178 , pp. 2067-2075
    • Ahmed, A.R.1    Yunis, J.J.2    Marcus-Bagley, D.3
  • 7
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi D.R., Cuenda A., Cohen P., et al. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 1995, 270:27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3
  • 8
    • 0034930533 scopus 로고    scopus 로고
    • Etanercept in rheumatoid arthritis
    • Alldred A. Etanercept in rheumatoid arthritis. Exp. Opin. Pharmacother. 2001, 2:1137-1148.
    • (2001) Exp. Opin. Pharmacother. , vol.2 , pp. 1137-1148
    • Alldred, A.1
  • 9
    • 0032993839 scopus 로고    scopus 로고
    • Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle
    • Alloatti G., Penna C., De Martino A., et al. Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-alpha in the guinea-pig papillary muscle. Cardiovasc. Res. 1999, 41:611-619.
    • (1999) Cardiovasc. Res. , vol.41 , pp. 611-619
    • Alloatti, G.1    Penna, C.2    De Martino, A.3
  • 10
    • 0033592892 scopus 로고    scopus 로고
    • Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators
    • An J., Ribeiro R.C., Webb P., et al. Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators. Proc. Natl Acad. Sci. USA 1999, 96:15161-15166.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 15161-15166
    • An, J.1    Ribeiro, R.C.2    Webb, P.3
  • 11
    • 0028306198 scopus 로고
    • HLA DR-DQ associations with cervical carcinoma show papillomavirus-type specificity
    • Apple R.J., Erlich H.A., Klitz W., et al. HLA DR-DQ associations with cervical carcinoma show papillomavirus-type specificity. Nat. Genet. 1994, 6:157-162.
    • (1994) Nat. Genet. , vol.6 , pp. 157-162
    • Apple, R.J.1    Erlich, H.A.2    Klitz, W.3
  • 12
    • 0025721017 scopus 로고
    • Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin
    • Ashkenazi A., Marsters S.A., Capon D.J., et al. Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. Proc. Natl Acad. Sci. USA 1991, 88:10535-10539.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 10535-10539
    • Ashkenazi, A.1    Marsters, S.A.2    Capon, D.J.3
  • 13
    • 0028867899 scopus 로고
    • Immuno-suppression by glucocorticoids: inhibition of NFκB activity through induction of Iκ-B synthesis
    • Auphan N., Di Donato J.A., Rosette C., et al. Immuno-suppression by glucocorticoids: inhibition of NFκB activity through induction of Iκ-B synthesis. Science 1995, 270:286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    Di Donato, J.A.2    Rosette, C.3
  • 14
    • 0026624743 scopus 로고
    • Phospholipase D activation in human natural killer cells through the KP43 and CD16 surface antigens takes place by different mechanisms. Involvement of the phospholipase D pathway in tumor necrosis factor-α synthesis
    • Balboa M.A., Balsinde J., Aramburu J., et al. Phospholipase D activation in human natural killer cells through the KP43 and CD16 surface antigens takes place by different mechanisms. Involvement of the phospholipase D pathway in tumor necrosis factor-α synthesis. J. Exp. Med. 1992, 176:9-17.
    • (1992) J. Exp. Med. , vol.176 , pp. 9-17
    • Balboa, M.A.1    Balsinde, J.2    Aramburu, J.3
  • 15
    • 0030034370 scopus 로고    scopus 로고
    • Structural changes of tumor necrosis factor α associated with membrane insertion and channel formation
    • Baldwin R.L., Stolowitz M.L., Hood L., et al. Structural changes of tumor necrosis factor α associated with membrane insertion and channel formation. Proc. Natl Acad. Sci. USA 1996, 93:1021-1026.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 1021-1026
    • Baldwin, R.L.1    Stolowitz, M.L.2    Hood, L.3
  • 16
    • 0028176580 scopus 로고
    • Dissociation of TNF-α cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-α mutants
    • Barbara J.A., Smith W.B., Gamble J.R., et al. Dissociation of TNF-α cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-α mutants. EMBO J. 1994, 13:843.
    • (1994) EMBO J. , vol.13 , pp. 843
    • Barbara, J.A.1    Smith, W.B.2    Gamble, J.R.3
  • 17
    • 0026767837 scopus 로고
    • Disease severity in rheumatoid arthritis: relationships of plasma tumor necrosis factor-alpha, soluble interleukin 2-receptor, soluble CD4/CD8 ratio, neopterin, and fibrin D-dimer to traditional severity and functional measures
    • Beckham J.C., Caldwell D.S., Peterson B.L., et al. Disease severity in rheumatoid arthritis: relationships of plasma tumor necrosis factor-alpha, soluble interleukin 2-receptor, soluble CD4/CD8 ratio, neopterin, and fibrin D-dimer to traditional severity and functional measures. J. Clin. Immunol. 1992, 12:353-361.
    • (1992) J. Clin. Immunol. , vol.12 , pp. 353-361
    • Beckham, J.C.1    Caldwell, D.S.2    Peterson, B.L.3
  • 18
    • 0035396688 scopus 로고    scopus 로고
    • Advances in the treatment of epilepsy
    • Benbadis S.R., Tatum W.O. Advances in the treatment of epilepsy. Am. Fam. Physician 2001, 64:91-98.
    • (2001) Am. Fam. Physician , vol.64 , pp. 91-98
    • Benbadis, S.R.1    Tatum, W.O.2
  • 19
    • 0024202995 scopus 로고
    • Association between HLA-DR2 and production of tumour necrosis factor α and interleukin 1 by mononuclear cells activated by lipopolysaccharide
    • Bendtzen K., Morling N., Fomsgaard A., et al. Association between HLA-DR2 and production of tumour necrosis factor α and interleukin 1 by mononuclear cells activated by lipopolysaccharide. Scand. J. Immunol. 1988, 28:599-606.
    • (1988) Scand. J. Immunol. , vol.28 , pp. 599-606
    • Bendtzen, K.1    Morling, N.2    Fomsgaard, A.3
  • 20
    • 84942894496 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates cardiac TNF production in endotoxic shock
    • Bernik T.R., Ivanova S.M., Ochani M., et al. Vagus nerve stimulation attenuates cardiac TNF production in endotoxic shock. Shock 2001, 15(Supp.):27.
    • (2001) Shock , vol.15 , Issue.SUPP. , pp. 27
    • Bernik, T.R.1    Ivanova, S.M.2    Ochani, M.3
  • 21
    • 0037128663 scopus 로고    scopus 로고
    • Systemic anti-inflammatory action of CNI-1493 is mediated by the cholinergic anti-inflammatory pathway
    • Bernik T.R., DiRaimo R., Friedman S.G., et al. Systemic anti-inflammatory action of CNI-1493 is mediated by the cholinergic anti-inflammatory pathway. J. Exp. Med. 2002, 18:781-788.
    • (2002) J. Exp. Med. , vol.18 , pp. 781-788
    • Bernik, T.R.1    DiRaimo, R.2    Friedman, S.G.3
  • 22
    • 0027456316 scopus 로고
    • Polymorphism of the tumor necrosis factor β gene in systemic lupus erythematosus: TNFB-MHC haplotypes
    • Bettinotti M.P., Hartung K., Deicher H., et al. Polymorphism of the tumor necrosis factor β gene in systemic lupus erythematosus: TNFB-MHC haplotypes. Immunogenetics 1993, 37:449-454.
    • (1993) Immunogenetics , vol.37 , pp. 449-454
    • Bettinotti, M.P.1    Hartung, K.2    Deicher, H.3
  • 23
    • 0022371461 scopus 로고
    • Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
    • Beutler B., Greenwald D., Hulmes J.D., et al. Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 1985, 316:552-554.
    • (1985) Nature , vol.316 , pp. 552-554
    • Beutler, B.1    Greenwald, D.2    Hulmes, J.D.3
  • 24
    • 0022508713 scopus 로고
    • Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance
    • Beutler B., Krochin N., Milsark I.W., et al. Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance. Science 1986, 232:977-980.
    • (1986) Science , vol.232 , pp. 977-980
    • Beutler, B.1    Krochin, N.2    Milsark, I.W.3
  • 25
    • 0000555820 scopus 로고
    • Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1
    • Bevilacqua M.P., Pober J.S., Majeau G.R., et al. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc. Natl Acad. Sci. USA 1986, 83:4533-4537.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 4533-4537
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3
  • 26
    • 15844399881 scopus 로고    scopus 로고
    • Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone
    • Bianchi M., Bloom O., Raabe T., et al. Suppression of proinflammatory cytokines in monocytes by a tetravalent guanylhydrazone. J. Exp. Med. 1996, 183:927-936.
    • (1996) J. Exp. Med. , vol.183 , pp. 927-936
    • Bianchi, M.1    Bloom, O.2    Raabe, T.3
  • 27
    • 0028535870 scopus 로고
    • Pentoxifylline and other protein kinase C inhibitors down-regulate HIV-LTR NFκB-induced gene expression
    • Biswas D.K., Ahlers C.M., Dezube B.J., et al. Pentoxifylline and other protein kinase C inhibitors down-regulate HIV-LTR NFκB-induced gene expression. Mol. Med. 1994, 1:31-43.
    • (1994) Mol. Med. , vol.1 , pp. 31-43
    • Biswas, D.K.1    Ahlers, C.M.2    Dezube, B.J.3
  • 28
    • 8044257704 scopus 로고    scopus 로고
    • A metal-loproteinase disintegrin that releases tumour-necrosis factor-α from cells
    • Black R.A., Rauch C.T., Kozlosky C.J., et al. A metal-loproteinase disintegrin that releases tumour-necrosis factor-α from cells. Nature 1997, 385:729-733.
    • (1997) Nature , vol.385 , pp. 729-733
    • Black, R.A.1    Rauch, C.T.2    Kozlosky, C.J.3
  • 29
    • 0023178374 scopus 로고
    • Phase I study of recombinant tumor necrosis factor in cancer patients
    • Blick M., Sherwin S.A., Rosenblum M., et al. Phase I study of recombinant tumor necrosis factor in cancer patients. Cancer Res. 1987, 47:2986-2989.
    • (1987) Cancer Res. , vol.47 , pp. 2986-2989
    • Blick, M.1    Sherwin, S.A.2    Rosenblum, M.3
  • 30
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β
    • Bogdan C., Paik J., Vodovotz Y., et al. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β. J. Biol. Chem. 1992, 267:23301-23308.
    • (1992) J. Biol. Chem. , vol.267 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3
  • 31
    • 0030994024 scopus 로고    scopus 로고
    • Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation
    • Boise LH., Thompson C.B. Bcl-x(L) can inhibit apoptosis in cells that have undergone Fas-induced protease activation. Proc. Natl Acad. Sci. USA 1997, 94:3759-3764.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 3759-3764
    • Boise, L.H.1    Thompson, C.B.2
  • 32
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of mach, a novel MORT1/FADD-interacting protease, in Fas/Apo-1- and TNF receptor-induced cell death
    • Boldin M.P., Goncharov T.M., Goltsev Y.V., et al. Involvement of mach, a novel MORT1/FADD-interacting protease, in Fas/Apo-1- and TNF receptor-induced cell death. Cell 1996, 85:803-815.
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3
  • 33
    • 0034695178 scopus 로고    scopus 로고
    • Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation
    • Borovikova L.V., Ivanova S., Nardi D., et al. Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation. Auton. Neurosci. 2000, 85:141-147.
    • (2000) Auton. Neurosci. , vol.85 , pp. 141-147
    • Borovikova, L.V.1    Ivanova, S.2    Nardi, D.3
  • 34
    • 0034713266 scopus 로고    scopus 로고
    • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin
    • Borovikova L.V., Ivanova S., Zhang M., et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000, 405:458-462.
    • (2000) Nature , vol.405 , pp. 458-462
    • Borovikova, L.V.1    Ivanova, S.2    Zhang, M.3
  • 35
    • 0027197004 scopus 로고
    • Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells
    • Bradley J.R., Johnson D.R., Pober J.S. Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells. J. Immunol. 1993, 150:5544-5555.
    • (1993) J. Immunol. , vol.150 , pp. 5544-5555
    • Bradley, J.R.1    Johnson, D.R.2    Pober, J.S.3
  • 36
    • 0024309730 scopus 로고
    • Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins
    • Brett J., Gerlach H., Nawroth P., et al. Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins. J. Exp. Med. 1989, 169:1977-1991.
    • (1989) J. Exp. Med. , vol.169 , pp. 1977-1991
    • Brett, J.1    Gerlach, H.2    Nawroth, P.3
  • 37
    • 0025238559 scopus 로고
    • Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies
    • Brockhaus M., Schoenfeld H.J., Schlaeger E.J., et al. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc. Natl Acad. Sci. USA 1990, 87:3127-3131.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 3127-3131
    • Brockhaus, M.1    Schoenfeld, H.J.2    Schlaeger, E.J.3
  • 38
    • 0029899586 scopus 로고    scopus 로고
    • Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
    • Bruce A.J., Boling W., Kindy M.S., et al. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat. Med. 1996, 2:788-794.
    • (1996) Nat. Med. , vol.2 , pp. 788-794
    • Bruce, A.J.1    Boling, W.2    Kindy, M.S.3
  • 39
    • 0025366738 scopus 로고
    • Tumor necrosis factor-α, but not lymphotoxin, stimulates growth of tumor cells in hairy cell leukemia
    • Buck C., Digel W., Schoniger W., et al. Tumor necrosis factor-α, but not lymphotoxin, stimulates growth of tumor cells in hairy cell leukemia. Leukemia 1990, 4:431-434.
    • (1990) Leukemia , vol.4 , pp. 431-434
    • Buck, C.1    Digel, W.2    Schoniger, W.3
  • 40
    • 0028832278 scopus 로고
    • Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis
    • Cabrera M., Shaw M.A., Sharpies C., et al. Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. J. Exp. Med. 1995, 182:1259-1264.
    • (1995) J. Exp. Med. , vol.182 , pp. 1259-1264
    • Cabrera, M.1    Shaw, M.A.2    Sharpies, C.3
  • 41
    • 0025266645 scopus 로고
    • Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-α and interferon-γ in the serum of patients with septic shock. Swiss-Dutch J5 immunoglobulin study group
    • Calandra T., Baumgartner J.D., Grau G.E., et al. Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-α and interferon-γ in the serum of patients with septic shock. Swiss-Dutch J5 immunoglobulin study group. J. Infect. Dis. 1990, 161:982-987.
    • (1990) J. Infect. Dis. , vol.161 , pp. 982-987
    • Calandra, T.1    Baumgartner, J.D.2    Grau, G.E.3
  • 42
    • 0028087329 scopus 로고
    • Polymorphism at the tumour necrosis factor locus: a marker of genetic predisposition to colorectal cancer?
    • (letter)
    • Campbell D.A., Field M., McArdle C.S., et al. Polymorphism at the tumour necrosis factor locus: a marker of genetic predisposition to colorectal cancer?. Lancet 1994, 343:293-294. (letter).
    • (1994) Lancet , vol.343 , pp. 293-294
    • Campbell, D.A.1    Field, M.2    McArdle, C.S.3
  • 43
    • 0000370303 scopus 로고
    • Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators
    • Caput D., Beutler B., Hartog K., et al. Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl Acad. Sci. USA 1986, 83:1670-1674.
    • (1986) Proc. Natl Acad. Sci. USA , vol.83 , pp. 1670-1674
    • Caput, D.1    Beutler, B.2    Hartog, K.3
  • 44
    • 0016723594 scopus 로고
    • An endotoxin-induced serum factor that causes necrosis of tumors
    • Carswell E.A., Old L.J., Kassel R.L., et al. An endotoxin-induced serum factor that causes necrosis of tumors. Proc. Natl Acad. Sci. USA 1975, 72:3666-3670.
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 3666-3670
    • Carswell, E.A.1    Old, L.J.2    Kassel, R.L.3
  • 45
    • 0031914977 scopus 로고    scopus 로고
    • High resolution crystal structure of a human tumor necrosis factor-α mutant with low systemic toxicity
    • Cha S.S., Kim J.S., Cho H.S., et al. High resolution crystal structure of a human tumor necrosis factor-α mutant with low systemic toxicity. J. Biol. Chem. 1998, 273:2153-2160.
    • (1998) J. Biol. Chem. , vol.273 , pp. 2153-2160
    • Cha, S.S.1    Kim, J.S.2    Cho, H.S.3
  • 46
    • 0030587125 scopus 로고    scopus 로고
    • Differential activation of the nuclear factorκB by TNF muteins specific for the p60 and p80 TNF receptors
    • Chainy G.B., Singh S., Raju U., et al. Differential activation of the nuclear factorκB by TNF muteins specific for the p60 and p80 TNF receptors. J. Immunol. 1996, 157:2410-2417.
    • (1996) J. Immunol. , vol.157 , pp. 2410-2417
    • Chainy, G.B.1    Singh, S.2    Raju, U.3
  • 47
    • 0028178798 scopus 로고
    • Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
    • Cheng B., Christakos S., Mattson M.P. Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis. Neuron 1994, 12:139-153.
    • (1994) Neuron , vol.12 , pp. 139-153
    • Cheng, B.1    Christakos, S.2    Mattson, M.P.3
  • 48
    • 0029917841 scopus 로고    scopus 로고
    • Tank, a co-inducer with TRAF2 of TNF- and CD 401-mediated NFκB activation
    • Cheng G., Baltimore D. Tank, a co-inducer with TRAF2 of TNF- and CD 401-mediated NFκB activation. Genes Dev. 1996, 10:963-973.
    • (1996) Genes Dev. , vol.10 , pp. 963-973
    • Cheng, G.1    Baltimore, D.2
  • 49
    • 0027405779 scopus 로고
    • Tumour necrosis factor soluble receptors behave as acute phase reactants following surgery in patients with rheumatoid arthritis, chronic osteomyelitis and osteoarthritis
    • Chikanza I.C., Roux-Lombard P., Dayer J.M., et al. Tumour necrosis factor soluble receptors behave as acute phase reactants following surgery in patients with rheumatoid arthritis, chronic osteomyelitis and osteoarthritis. Clin. Exp. Immunol. 1993, 92:19-22.
    • (1993) Clin. Exp. Immunol. , vol.92 , pp. 19-22
    • Chikanza, I.C.1    Roux-Lombard, P.2    Dayer, J.M.3
  • 50
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan A.M., O'Rourke K., Tewari M., et al. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995, 81:505-512.
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3
  • 51
    • 0026091413 scopus 로고
    • Localization of tumor necrosis factor-a in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
    • Chu C.Q., Field M., Feldman M., et al. Localization of tumor necrosis factor-a in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum. 1991, 34:1125-1132.
    • (1991) Arthritis Rheum. , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldman, M.3
  • 52
    • 0032989434 scopus 로고    scopus 로고
    • Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3
    • Coeshott C., Ohnemus C., Pilyavskaya A., et al. Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc. Natl Acad. Sci. USA 1999, 96:6261-6266.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 6261-6266
    • Coeshott, C.1    Ohnemus, C.2    Pilyavskaya, A.3
  • 53
    • 0033549557 scopus 로고    scopus 로고
    • DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain
    • Cohen O., Inbal B., Kissil J.L., et al. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. J. Cell Biol. 1999, 146:141-148.
    • (1999) J. Cell Biol. , vol.146 , pp. 141-148
    • Cohen, O.1    Inbal, B.2    Kissil, J.L.3
  • 54
    • 0029991493 scopus 로고    scopus 로고
    • CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency
    • Cohen P.S., Nakshatri H., Dennis J., et al. CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency. Proc. Natl Acad. Sci. USA 1996, 93:3967-3971.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 3967-3971
    • Cohen, P.S.1    Nakshatri, H.2    Dennis, J.3
  • 55
    • 0033527064 scopus 로고    scopus 로고
    • PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis
    • Condorelli G., Vigliotta G., Cafieri A., et al. PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis. Oncogene 1999, 18:4409-4415.
    • (1999) Oncogene , vol.18 , pp. 4409-4415
    • Condorelli, G.1    Vigliotta, G.2    Cafieri, A.3
  • 56
    • 0028279896 scopus 로고
    • Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor α with human IDDM
    • Cox A., Gonzalez A.M., Wilson A.G., et al. Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor α with human IDDM. Diabetologia 1994, 37:500-503.
    • (1994) Diabetologia , vol.37 , pp. 500-503
    • Cox, A.1    Gonzalez, A.M.2    Wilson, A.G.3
  • 57
    • 0030868611 scopus 로고    scopus 로고
    • The role of 3' poly(A) tail metabolism in tumor necrosis factor-alpha regulation
    • Crawford E.K., Ensor J.E., Kalvakolanu I., et al. The role of 3' poly(A) tail metabolism in tumor necrosis factor-alpha regulation. J. Biol. Chem. 1997, 272:21120-21127.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21120-21127
    • Crawford, E.K.1    Ensor, J.E.2    Kalvakolanu, I.3
  • 58
    • 0023149684 scopus 로고
    • Biological effects of recombinant human tumor necrosis factor and its novel muteins on tumor and normal cell lines
    • Creasey AA., Doyle L.V., Reynolds M.T., et al. Biological effects of recombinant human tumor necrosis factor and its novel muteins on tumor and normal cell lines. Cancer Res. 1987, 47:145-149.
    • (1987) Cancer Res. , vol.47 , pp. 145-149
    • Creasey, A.A.1    Doyle, L.V.2    Reynolds, M.T.3
  • 59
    • 0029090390 scopus 로고
    • Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature
    • Cronin L., Cook D.J., Carlet J., et al. Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit. Care Med. 1995, 23:1430-1439.
    • (1995) Crit. Care Med. , vol.23 , pp. 1430-1439
    • Cronin, L.1    Cook, D.J.2    Carlet, J.3
  • 60
    • 0028919856 scopus 로고
    • A metal-loprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes
    • Crowe P.D., Walter B.X., Mohler K.M., et al. A metal-loprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes. J. Exp. Med. 1995, 181:1205-1210.
    • (1995) J. Exp. Med. , vol.181 , pp. 1205-1210
    • Crowe, P.D.1    Walter, B.X.2    Mohler, K.M.3
  • 61
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda A., Rouse J., Doza Y.N., et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 1995, 364:229-233.
    • (1995) FEBS Lett. , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3
  • 62
    • 0028366342 scopus 로고
    • A polymorphic variation in a putative regulation box of the TNFA promoter region
    • D'Alfonso S., Richiardi P.M. A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics 1994, 39:150-154.
    • (1994) Immunogenetics , vol.39 , pp. 150-154
    • D'Alfonso, S.1    Richiardi, P.M.2
  • 63
    • 0029928977 scopus 로고    scopus 로고
    • Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population
    • D'Alfonso S., Colombo G., Della Bella S., et al. Association between polymorphisms in the TNF region and systemic lupus erythematosus in the Italian population. Tissue Antigens 1996, 47:551-555.
    • (1996) Tissue Antigens , vol.47 , pp. 551-555
    • D'Alfonso, S.1    Colombo, G.2    Della Bella, S.3
  • 64
    • 0034746363 scopus 로고    scopus 로고
    • The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR
    • Dean J.L., Wait R., Mahtani K.R., et al. The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR. Mol. Cell Biol. 2001, 21:721-730.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 721-730
    • Dean, J.L.1    Wait, R.2    Mahtani, K.R.3
  • 65
    • 0033215445 scopus 로고    scopus 로고
    • The effect of a metalloproteinase inhibitor (GI5402) on tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha receptors during human endotoxemia
    • Dekkers P.E., Lauw F.N., ten Hove T., et al. The effect of a metalloproteinase inhibitor (GI5402) on tumor necrosis factor-alpha (TNF-alpha) and TNF-alpha receptors during human endotoxemia. Blood 1999, 94:2252-2258.
    • (1999) Blood , vol.94 , pp. 2252-2258
    • Dekkers, P.E.1    Lauw, F.N.2    ten Hove, T.3
  • 66
    • 0033860691 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen activated kinase attenuates the severity of pancreatitis-induced adult respiratory distress syndrome
    • Denham W., Yang J., Wang H., et al. Inhibition of p38 mitogen activated kinase attenuates the severity of pancreatitis-induced adult respiratory distress syndrome. Crit. Care Med. 2000, 28:2567-2572.
    • (2000) Crit. Care Med. , vol.28 , pp. 2567-2572
    • Denham, W.1    Yang, J.2    Wang, H.3
  • 67
    • 0029132699 scopus 로고
    • CDP571, a humanized antibody to human tumor necrosis factor-alpha: safety, pharmacokinetics, immune response, and influence of the antibody on cytokine concentrations in patients with septic shock. CPD571 Sepsis Study Group
    • Dhainaut J.F., Vincent J.L., Richard C., et al. CDP571, a humanized antibody to human tumor necrosis factor-alpha: safety, pharmacokinetics, immune response, and influence of the antibody on cytokine concentrations in patients with septic shock. CPD571 Sepsis Study Group. Crit. Care Med. 1995, 23:1461-1469.
    • (1995) Crit. Care Med. , vol.23 , pp. 1461-1469
    • Dhainaut, J.F.1    Vincent, J.L.2    Richard, C.3
  • 68
    • 0035864364 scopus 로고    scopus 로고
    • Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA
    • Di Marco S., Hel Z., Lachance C., et al. Polymorphism in the 3'-untranslated region of TNFalpha mRNA impairs binding of the post-transcriptional regulatory protein HuR to TNFalpha mRNA. Nucleic Acids Res. 2001, 29:863-871.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 863-871
    • Di Marco, S.1    Hel, Z.2    Lachance, C.3
  • 69
    • 0031021356 scopus 로고    scopus 로고
    • RAIDD is a new 'death' adaptor molecule
    • Duan H., Dixit V.M. RAIDD is a new 'death' adaptor molecule. Nature 1997, 385:86-89.
    • (1997) Nature , vol.385 , pp. 86-89
    • Duan, H.1    Dixit, V.M.2
  • 70
    • 0026670962 scopus 로고
    • Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages
    • Duerksen-Hughes P.J., Day D.B., Laster S.M., et al. Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages. J. Immunol. 1992, 149:2114-2122.
    • (1992) J. Immunol. , vol.149 , pp. 2114-2122
    • Duerksen-Hughes, P.J.1    Day, D.B.2    Laster, S.M.3
  • 71
    • 0026779627 scopus 로고
    • Nitric oxide mediates tumor necrosis factor-α cytotoxicity in endothelial cells
    • Estrada C., Gomez C., Martin C., et al. Nitric oxide mediates tumor necrosis factor-α cytotoxicity in endothelial cells. Biochem. Biophys. Res. Commun. 1992, 186:475-482.
    • (1992) Biochem. Biophys. Res. Commun. , vol.186 , pp. 475-482
    • Estrada, C.1    Gomez, C.2    Martin, C.3
  • 72
    • 0036138727 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha gene polymorphism in severe and mildmoderate rheumatoid arthritis
    • Fabris M., Di P.E., D'Elia A., et al. Tumor necrosis factor-alpha gene polymorphism in severe and mildmoderate rheumatoid arthritis. J. Rheumatol. 2002, 29:29-33.
    • (2002) J. Rheumatol. , vol.29 , pp. 29-33
    • Fabris, M.1    Di, P.E.2    D'Elia, A.3
  • 73
    • 0035056003 scopus 로고    scopus 로고
    • Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?
    • Feldmann M., Maini R.N. Anti-TNF alpha therapy of rheumatoid arthritis: what have we learned?. Annu. Rev. Immunol. 2001, 19:163-196.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 163-196
    • Feldmann, M.1    Maini, R.N.2
  • 74
    • 0032740614 scopus 로고    scopus 로고
    • Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase
    • Feng G.J., Goodridge H.S., Harnett M.M., et al. Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase. J. Immunol. 1999, 163:6403-6412.
    • (1999) J. Immunol. , vol.163 , pp. 6403-6412
    • Feng, G.J.1    Goodridge, H.S.2    Harnett, M.M.3
  • 75
    • 0025807206 scopus 로고
    • Elevated circulating tumor necrosis factor levels in Alzheimer's disease
    • Fillit H., Ding W.H., Buee L., et al. Elevated circulating tumor necrosis factor levels in Alzheimer's disease. Neurosci. Lett. 1991, 129:318-320.
    • (1991) Neurosci. Lett. , vol.129 , pp. 318-320
    • Fillit, H.1    Ding, W.H.2    Buee, L.3
  • 76
    • 0026735208 scopus 로고
    • Negative inotropic effects of cytokines on the heart mediated by nitric oxide
    • Finkel M.S., Oddis C.V., Jacob T.D., et al. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 1992, 257:387-389.
    • (1992) Science , vol.257 , pp. 387-389
    • Finkel, M.S.1    Oddis, C.V.2    Jacob, T.D.3
  • 77
    • 0028872096 scopus 로고
    • Characterization of protein complexes formed on the repressor elements of the human tumor necrosis factor alpha gene
    • Fong C.W., Siddiqui A.H., Mark D.F. Characterization of protein complexes formed on the repressor elements of the human tumor necrosis factor alpha gene. J. Interferon Cytokine Res. 1995, 15:887-895.
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 887-895
    • Fong, C.W.1    Siddiqui, A.H.2    Mark, D.F.3
  • 78
    • 0024822793 scopus 로고
    • Antibodies to cachectin/tumor necrosis factor reduce interleukin 1β and interleukin 6 appearance during lethal bacteremia
    • Fong Y., Tracey K.J., Moldawer L.L., et al. Antibodies to cachectin/tumor necrosis factor reduce interleukin 1β and interleukin 6 appearance during lethal bacteremia. J. Exp. Med. 1989, 170:1627-1633.
    • (1989) J. Exp. Med. , vol.170 , pp. 1627-1633
    • Fong, Y.1    Tracey, K.J.2    Moldawer, L.L.3
  • 79
    • 0024997223 scopus 로고
    • Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes
    • Gadient R.A., Cron K.C., Otten U. Interleukin-1β and tumor necrosis factor-α synergistically stimulate nerve growth factor (NGF) release from cultured rat astrocytes. Neurosci. Lett. 1990, 117:335-340.
    • (1990) Neurosci. Lett. , vol.117 , pp. 335-340
    • Gadient, R.A.1    Cron, K.C.2    Otten, U.3
  • 80
    • 0026002704 scopus 로고
    • The regulation of TNF receptor mRNA synthesis, membrane expression, and release by PMA- and LPS-stimulated human monocytic THP-1 cells in vitro
    • Gatanaga T., Hwang C.D., Gatanaga M., et al. The regulation of TNF receptor mRNA synthesis, membrane expression, and release by PMA- and LPS-stimulated human monocytic THP-1 cells in vitro. Cell Immunol. 1991, 138:1-10.
    • (1991) Cell Immunol. , vol.138 , pp. 1-10
    • Gatanaga, T.1    Hwang, C.D.2    Gatanaga, M.3
  • 81
    • 0028485654 scopus 로고
    • Processing of tumour necrosis factor-α precursor by metalloproteinases
    • Gearing A.J., Beckett P., Christodoulou M., et al. Processing of tumour necrosis factor-α precursor by metalloproteinases. Nature 1994, 370:555-557.
    • (1994) Nature , vol.370 , pp. 555-557
    • Gearing, A.J.1    Beckett, P.2    Christodoulou, M.3
  • 82
    • 0029069565 scopus 로고
    • Matrix metalloproteinases and processing of pro-TNF-α
    • Gearing A.J., Beckett P., Christodoulou M., et al. Matrix metalloproteinases and processing of pro-TNF-α. J. Leukoc. Biol. 1995, 57:774-777.
    • (1995) J. Leukoc. Biol. , vol.57 , pp. 774-777
    • Gearing, A.J.1    Beckett, P.2    Christodoulou, M.3
  • 83
    • 0023749693 scopus 로고
    • Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura
    • Girardin E., Grau G.E., Dayer J.M., et al. Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. N. Engl. J. Med. 1988, 319:397-400.
    • (1988) N. Engl. J. Med. , vol.319 , pp. 397-400
    • Girardin, E.1    Grau, G.E.2    Dayer, J.M.3
  • 84
    • 0026708465 scopus 로고
    • Imbalance between tumour necrosis factor-α and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group
    • Girardin E., Roux-Lombard P., Grau G.E., et al. Imbalance between tumour necrosis factor-α and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group. Immunology 1992, 76:20-23.
    • (1992) Immunology , vol.76 , pp. 20-23
    • Girardin, E.1    Roux-Lombard, P.2    Grau, G.E.3
  • 85
    • 0027969239 scopus 로고
    • Inhibition of tumor necrosis factor prevents myocardial dysfunction during burn shock
    • Giroir B.P., Horton J.W., White D.J., et al. Inhibition of tumor necrosis factor prevents myocardial dysfunction during burn shock. Am. J. Physiol. 1994, 267:H118-H124.
    • (1994) Am. J. Physiol. , vol.267 , pp. H118-H124
    • Giroir, B.P.1    Horton, J.W.2    White, D.J.3
  • 86
    • 0027326457 scopus 로고
    • Identification of a novel cyclopsporin-sensitive element in the human tumor necrosis factor α gene promoter
    • Goldfeld A.E., McCaffrey P.G., Strominger J.L., et al. Identification of a novel cyclopsporin-sensitive element in the human tumor necrosis factor α gene promoter. J. Exp. Med. 1993, 178:1365-1379.
    • (1993) J. Exp. Med. , vol.178 , pp. 1365-1379
    • Goldfeld, A.E.1    McCaffrey, P.G.2    Strominger, J.L.3
  • 88
    • 0028866022 scopus 로고
    • The transmenbrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
    • Grell M., Douni E., Wajant H., et al. The transmenbrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor. Cell 1995, 83:793-802.
    • (1995) Cell , vol.83 , pp. 793-802
    • Grell, M.1    Douni, E.2    Wajant, H.3
  • 89
    • 0025969055 scopus 로고
    • Elevated α-tumor necrosis factor levels in spinal fluid from HIV-1-infected patients with central nervous system involvement
    • Grimaldi L.M., Martino G.V., Franciotta D.M., et al. Elevated α-tumor necrosis factor levels in spinal fluid from HIV-1-infected patients with central nervous system involvement. Ann. Neurol. 1991, 29:21-25.
    • (1991) Ann. Neurol. , vol.29 , pp. 21-25
    • Grimaldi, L.M.1    Martino, G.V.2    Franciotta, D.M.3
  • 90
    • 0029760732 scopus 로고    scopus 로고
    • RIP and FADD: two 'death domain'-containing proteins can induce apoptosis by convergent, but dissociable, pathways
    • Grimm S., Stanger B.Z., Leder P. RIP and FADD: two 'death domain'-containing proteins can induce apoptosis by convergent, but dissociable, pathways. Proc. Natl Acad. Sci. USA 1996, 93:10923-10927.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10923-10927
    • Grimm, S.1    Stanger, B.Z.2    Leder, P.3
  • 91
    • 0033593448 scopus 로고    scopus 로고
    • Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA
    • Gueydan C., Droogmans L., Chalon P., et al. Identification of TIAR as a protein binding to the translational regulatory AU-rich element of tumor necrosis factor alpha mRNA. J. Biol. Chem. 1999, 274:2322-2326.
    • (1999) J. Biol. Chem. , vol.274 , pp. 2322-2326
    • Gueydan, C.1    Droogmans, L.2    Chalon, P.3
  • 92
    • 0035469890 scopus 로고    scopus 로고
    • Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression
    • Guha M., O'Connell M.A., Pawlinski R., et al. Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 2001, 98:1429-1439.
    • (2001) Blood , vol.98 , pp. 1429-1439
    • Guha, M.1    O'Connell, M.A.2    Pawlinski, R.3
  • 93
    • 0030603619 scopus 로고    scopus 로고
    • Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy
    • Habib F.M., Springall D.R., Davies G.J., et al. Tumour necrosis factor and inducible nitric oxide synthase in dilated cardiomyopathy. Lancet. 1996, 347:1151-1155.
    • (1996) Lancet. , vol.347 , pp. 1151-1155
    • Habib, F.M.1    Springall, D.R.2    Davies, G.J.3
  • 94
    • 0025282043 scopus 로고
    • Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway
    • Han J., Thompson P., Beutler B. Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway. J. Exp. Med. 1990, 172:391-394.
    • (1990) J. Exp. Med. , vol.172 , pp. 391-394
    • Han, J.1    Thompson, P.2    Beutler, B.3
  • 95
    • 0025055476 scopus 로고
    • TNF-induced cardiomyopathy
    • (letter)
    • Hegewisch S., Weh H.J., Hossfeld D.K. TNF-induced cardiomyopathy. Lancet 1990, 335:294-295. (letter).
    • (1990) Lancet , vol.335 , pp. 294-295
    • Hegewisch, S.1    Weh, H.J.2    Hossfeld, D.K.3
  • 96
    • 0026734195 scopus 로고
    • Malaria resistance genes: a natural selection
    • Hill A.V. Malaria resistance genes: a natural selection. Trans. R. Soc. Trop. Med. Hyg. 1992, 86:225-226.
    • (1992) Trans. R. Soc. Trop. Med. Hyg. , vol.86 , pp. 225-226
    • Hill, A.V.1
  • 97
    • 0026734195 scopus 로고
    • Malaria resistance genes: a natural selection
    • Hill A.V. Malaria resistance genes: a natural selection. Trans. R. Soc. Trop. Med. Hyg. 1992, 86:232.
    • (1992) Trans. R. Soc. Trop. Med. Hyg. , vol.86 , pp. 232
    • Hill, A.V.1
  • 98
    • 0024366885 scopus 로고
    • Tumor necrosis factor identified in multiple sclerosis brain
    • Hofman P.M., Hinton D.R., Johnson K., et al. Tumor necrosis factor identified in multiple sclerosis brain. J. Exp. Med. 1989, 170:607-612.
    • (1989) J. Exp. Med. , vol.170 , pp. 607-612
    • Hofman, P.M.1    Hinton, D.R.2    Johnson, K.3
  • 99
    • 0024448122 scopus 로고
    • Two different cell types have different major receptors for human tumor necrosis factor (TNF-α)
    • Hohmann H.P., Remy R., Brockhaus M., et al. Two different cell types have different major receptors for human tumor necrosis factor (TNF-α). J. Biol. Chem. 1989, 264:14927-14934.
    • (1989) J. Biol. Chem. , vol.264 , pp. 14927-14934
    • Hohmann, H.P.1    Remy, R.2    Brockhaus, M.3
  • 100
    • 0025609639 scopus 로고
    • Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NFκB. TNF-α is not needed for induction of a biological effect via TNF receptors
    • Hohmann H.P., Brockhaus M., Baeuerle P.A., et al. Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NFκB. TNF-α is not needed for induction of a biological effect via TNF receptors. J. Biol. Chem. 1990, 265:22409-22417.
    • (1990) J. Biol. Chem. , vol.265 , pp. 22409-22417
    • Hohmann, H.P.1    Brockhaus, M.2    Baeuerle, P.A.3
  • 101
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NFκB activation
    • Hsu H., Xiong J., Goeddel D.V. The TNF receptor 1-associated protein TRADD signals cell death and NFκB activation. Cell 1995, 81:495-504.
    • (1995) Cell , vol.81 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 102
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • Hsu H., Shu H.B., Pan M.G., et al. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 1996, 84:299-308.
    • (1996) Cell , vol.84 , pp. 299-308
    • Hsu, H.1    Shu, H.B.2    Pan, M.G.3
  • 103
    • 0025016823 scopus 로고
    • Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus
    • Jacob C.O., Fronek Z., Lewis G.D., et al. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc. Natl Acad. Sci. USA 1990, 87:1233-1237.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 1233-1237
    • Jacob, C.O.1    Fronek, Z.2    Lewis, G.D.3
  • 104
    • 0024539057 scopus 로고
    • Structure of tumour necrosis factor
    • Jones E.Y., Stuart D.I., Walker N.P. Structure of tumour necrosis factor. Nature 1989, 338:225-228.
    • (1989) Nature , vol.338 , pp. 225-228
    • Jones, E.Y.1    Stuart, D.I.2    Walker, N.P.3
  • 105
    • 0026093774 scopus 로고
    • Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes
    • Jongeneel C.V., Briant L., Udalova I.A., et al. Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes. Proc. Natl Acad. Sci. USA 1991, 88:9717-9721.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 9717-9721
    • Jongeneel, C.V.1    Briant, L.2    Udalova, I.A.3
  • 106
    • 0034189490 scopus 로고    scopus 로고
    • TNF-alpha antagonist for the treatment of Crohn's disease
    • Kam L.Y., Targan S.R. TNF-alpha antagonist for the treatment of Crohn's disease. Expert Opin. Pharmacother. 2000, 1:615-622.
    • (2000) Expert Opin. Pharmacother. , vol.1 , pp. 615-622
    • Kam, L.Y.1    Targan, S.R.2
  • 107
    • 0028898719 scopus 로고
    • Soluble TNF binding proteins modulate the negative inotropic properties of TNF-α in vitro
    • Kapadia S., Torre-Amione G., Yokoyama T., et al. Soluble TNF binding proteins modulate the negative inotropic properties of TNF-α in vitro. Am. J. Physiol. 1995, 268:H517-H525.
    • (1995) Am. J. Physiol. , vol.268 , pp. H517-H525
    • Kapadia, S.1    Torre-Amione, G.2    Yokoyama, T.3
  • 108
    • 0028356323 scopus 로고
    • Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation
    • Katz S.D., Rao R., Berman J.W., et al. Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure. Relation to nitric oxide-dependent vasodilation in the forearm circulation. Circulation 1994, 90:12-16.
    • (1994) Circulation , vol.90 , pp. 12-16
    • Katz, S.D.1    Rao, R.2    Berman, J.W.3
  • 109
    • 0025096274 scopus 로고
    • A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor
    • Kohno T., Brewer M.T., Baker S.L., et al. A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor. Proc. Natl Acad. Sci. USA 1990, 87:8331-8335.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 8331-8335
    • Kohno, T.1    Brewer, M.T.2    Baker, S.L.3
  • 110
    • 0035794112 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces distinctive NFκB signaling within human dermal fibroblasts
    • Kouba D.J., Nakano H., Nishiyama T., et al. Tumor necrosis factor-α induces distinctive NFκB signaling within human dermal fibroblasts. J. Biol. Chem. 2001, 276:6214-6224.
    • (2001) J. Biol. Chem. , vol.276 , pp. 6214-6224
    • Kouba, D.J.1    Nakano, H.2    Nishiyama, T.3
  • 111
    • 0027973632 scopus 로고
    • Characterization of a KROX-24/EGR-1-responsive element in the human tumor necrosis factor promoter
    • Kramer B., Meichle A., Hensel G., et al. Characterization of a KROX-24/EGR-1-responsive element in the human tumor necrosis factor promoter. Biochim. Biophys. Acta 1994, 1219:413-421.
    • (1994) Biochim. Biophys. Acta , vol.1219 , pp. 413-421
    • Kramer, B.1    Meichle, A.2    Hensel, G.3
  • 112
    • 0028931318 scopus 로고
    • Regulation of the human TNF promoter by the transcription factor Ets
    • Kramer B., Wiegmann K., Kronke M. Regulation of the human TNF promoter by the transcription factor Ets. J. Biol. Chem. 1995, 270:6577-6583.
    • (1995) J. Biol. Chem. , vol.270 , pp. 6577-6583
    • Kramer, B.1    Wiegmann, K.2    Kronke, M.3
  • 113
    • 0024281428 scopus 로고
    • A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF
    • Kriegler M., Perez C., De Fay K., et al. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: ramifications for the complex physiology of TNF. Cell 1988, 53:45-53.
    • (1988) Cell , vol.53 , pp. 45-53
    • Kriegler, M.1    Perez, C.2    De Fay, K.3
  • 114
    • 0024432688 scopus 로고
    • Translational blockade imposed by cytokine-derived UA-rich sequences
    • Kruys V., Marinx O., Shaw G., et al. Translational blockade imposed by cytokine-derived UA-rich sequences. Science 1989, 245:852-855.
    • (1989) Science , vol.245 , pp. 852-855
    • Kruys, V.1    Marinx, O.2    Shaw, G.3
  • 115
    • 0025015479 scopus 로고
    • TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria
    • Kwiatkowski D., Hill A.V., Sambou I., et al. TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria. Lancet 1990, 336:1201-1204.
    • (1990) Lancet , vol.336 , pp. 1201-1204
    • Kwiatkowski, D.1    Hill, A.V.2    Sambou, I.3
  • 116
    • 0026669753 scopus 로고
    • Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4
    • Lacraz S., Nicod L., Galve-de Rocnemonteix B., et al. Suppression of metalloproteinase biosynthesis in human alveolar macrophages by interleukin-4. J. Clin. Invest. 1992, 90:382-388.
    • (1992) J. Clin. Invest. , vol.90 , pp. 382-388
    • Lacraz, S.1    Nicod, L.2    Galve-de Rocnemonteix, B.3
  • 117
    • 0028855894 scopus 로고
    • IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
    • Lacraz S., Nicod L.P., Chicheportiche R., et al. IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J. Clin. Invest. 1995, 96:2304-2310.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2304-2310
    • Lacraz, S.1    Nicod, L.P.2    Chicheportiche, R.3
  • 118
    • 0033049125 scopus 로고    scopus 로고
    • Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
    • Lai W.S., Carballo E., Strum J.R., et al. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol. Cell. Biol. 1999, 19:4311-4323.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4311-4323
    • Lai, W.S.1    Carballo, E.2    Strum, J.R.3
  • 119
    • 0030042886 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells
    • Lee E., Vaughan D.E., Parikh S.H., et al. Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells. Circ. Res. 1996, 78:44-49.
    • (1996) Circ. Res. , vol.78 , pp. 44-49
    • Lee, E.1    Vaughan, D.E.2    Parikh, S.H.3
  • 120
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway
    • Lee F.S., Hagler J., Chen Z.J., et al. Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 1997, 88:213-222.
    • (1997) Cell , vol.88 , pp. 213-222
    • Lee, F.S.1    Hagler, J.2    Chen, Z.J.3
  • 121
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee J.C., Laydon J.T., McDonnell P.C., et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372:739-746.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 122
    • 0028256029 scopus 로고
    • Slow release of soluble TNF receptors by monocytes in vitro
    • Leeuwenberg J.F., Jeunhomme T.M., Buurman W.A. Slow release of soluble TNF receptors by monocytes in vitro. J. Immunol. 1994, 152:4036-4043.
    • (1994) J. Immunol. , vol.152 , pp. 4036-4043
    • Leeuwenberg, J.F.1    Jeunhomme, T.M.2    Buurman, W.A.3
  • 123
    • 0023890129 scopus 로고
    • Tumor necrosis factor-α in cerebrospinal fluid during bacterial, but not viral, meninigitis. Evaluation in murine model infections and in patients
    • Leist T.P., Frei I.C., Kam-Hansen S., et al. Tumor necrosis factor-α in cerebrospinal fluid during bacterial, but not viral, meninigitis. Evaluation in murine model infections and in patients. J. Exp. Med. 1988, 167:1743-1748.
    • (1988) J. Exp. Med. , vol.167 , pp. 1743-1748
    • Leist, T.P.1    Frei, I.C.2    Kam-Hansen, S.3
  • 124
    • 0026608675 scopus 로고
    • The core promoter region of the tumor necrosis factor α gene confers phorbol ester responsiveness to upstream transcriptional activators
    • Leitman D.C., Mackow E.R., Williams T., et al. The core promoter region of the tumor necrosis factor α gene confers phorbol ester responsiveness to upstream transcriptional activators. Mol. Cell Biol. 1992, 12:1352-1356.
    • (1992) Mol. Cell Biol. , vol.12 , pp. 1352-1356
    • Leitman, D.C.1    Mackow, E.R.2    Williams, T.3
  • 125
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B., Kalman J., Mayer L., et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N. Engl. J. Med. 1990, 323:236-241.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3
  • 126
    • 0026531756 scopus 로고
    • High-dose recombinant tumor necrosis factor α in combination with interferon γ and melphalan in isolation perfusion of the limbs for melanoma and sarcoma
    • Lienard D., Ewalenko P., Delmotte J.J., et al. High-dose recombinant tumor necrosis factor α in combination with interferon γ and melphalan in isolation perfusion of the limbs for melanoma and sarcoma. J. Clin. Oncol. 1992, 10:52-60.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 52-60
    • Lienard, D.1    Ewalenko, P.2    Delmotte, J.J.3
  • 127
    • 0024327280 scopus 로고
    • Pentoxifylline prevents tumor necrosis factor-induced lung injury
    • Lilly C.M., Sandhu J.S., Ishizaka A., et al. Pentoxifylline prevents tumor necrosis factor-induced lung injury. Am. Rev. Respir. Dis. 1989, 139:1361-1368.
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 1361-1368
    • Lilly, C.M.1    Sandhu, J.S.2    Ishizaka, A.3
  • 128
    • 0027338999 scopus 로고
    • CPLA2 is phosphorylated and activated by MAP kinase
    • Lin L.L., Wartmann M., Lin A.Y., et al. CPLA2 is phosphorylated and activated by MAP kinase. Cell 1993, 72:269-278.
    • (1993) Cell , vol.72 , pp. 269-278
    • Lin, L.L.1    Wartmann, M.2    Lin, A.Y.3
  • 130
    • 0031567897 scopus 로고    scopus 로고
    • TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation
    • Lin R.H., Hwang Y.W., Yang B.C., et al. TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation. J. Immunol. 1997, 158:598-603.
    • (1997) J. Immunol. , vol.158 , pp. 598-603
    • Lin, R.H.1    Hwang, Y.W.2    Yang, B.C.3
  • 131
    • 0028292231 scopus 로고
    • Tumor necrosis factor-alpha expression in ischemic neurons
    • Liu T., Clark R.K., McDonnell P.C., et al. Tumor necrosis factor-alpha expression in ischemic neurons. Stroke 1994, 25:1481-1488.
    • (1994) Stroke , vol.25 , pp. 1481-1488
    • Liu, T.1    Clark, R.K.2    McDonnell, P.C.3
  • 132
    • 0030298294 scopus 로고    scopus 로고
    • Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NFκB activation prevents cell death
    • Liu Z.G., Hsu H., Goeddel D.V., et al. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NFκB activation prevents cell death. Cell 1996, 87:565-576.
    • (1996) Cell , vol.87 , pp. 565-576
    • Liu, Z.G.1    Hsu, H.2    Goeddel, D.V.3
  • 133
    • 0027382150 scopus 로고
    • Human tumor necrosis factor α (TNF α) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors
    • Loetscher H., Stueber O., Banner D., et al. Human tumor necrosis factor α (TNF α) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors. J. Biol. Chem. 1993, 268:26350-26357.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26350-26357
    • Loetscher, H.1    Stueber, O.2    Banner, D.3
  • 134
    • 0034673697 scopus 로고    scopus 로고
    • Etanercept in children with plyarticular juvenile rheumatoid arthritis
    • Lovell D.J., Giannini E.H., Reiff A., et al. Etanercept in children with plyarticular juvenile rheumatoid arthritis. N. Engl J. Med. 2000, 342:763-769.
    • (2000) N. Engl J. Med. , vol.342 , pp. 763-769
    • Lovell, D.J.1    Giannini, E.H.2    Reiff, A.3
  • 135
    • 0029812902 scopus 로고    scopus 로고
    • Function of the p55 tumor necrosis factor receptor 'death domain' mediated by phosphatidylcholine-specific phospholipase C
    • Machleidt T., Kramer B., Adam D., et al. Function of the p55 tumor necrosis factor receptor 'death domain' mediated by phosphatidylcholine-specific phospholipase C. J. Exp. Med. 1996, 184:725-733.
    • (1996) J. Exp. Med. , vol.184 , pp. 725-733
    • Machleidt, T.1    Kramer, B.2    Adam, D.3
  • 136
    • 0028149960 scopus 로고
    • Differential responses of fibroblasts from wild-type and TNF-r55-deficient mice to mouse and human TNF-α activation
    • Mackay F., Rothe J., Bluethmann H., et al. Differential responses of fibroblasts from wild-type and TNF-r55-deficient mice to mouse and human TNF-α activation. J. Immunol. 1994, 153:5274-5284.
    • (1994) J. Immunol. , vol.153 , pp. 5274-5284
    • Mackay, F.1    Rothe, J.2    Bluethmann, H.3
  • 137
    • 0033524159 scopus 로고    scopus 로고
    • Infliximab (chimeric anti-tumour necrosis factor-α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial
    • Maini R., St.Clair E.W., Breeveld F., et al. Infliximab (chimeric anti-tumour necrosis factor-α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. Lancet 1999, 354:1932-1939.
    • (1999) Lancet , vol.354 , pp. 1932-1939
    • Maini, R.1    St.Clair, E.W.2    Breeveld, F.3
  • 138
    • 0033498342 scopus 로고    scopus 로고
    • Relation of a TNF gene polymorphism to severe sepsis in trauma patients
    • Majetschak M., Flohe S., Obertacke U., et al. Relation of a TNF gene polymorphism to severe sepsis in trauma patients. Ann. Surg. 1999, 230:207-214.
    • (1999) Ann. Surg. , vol.230 , pp. 207-214
    • Majetschak, M.1    Flohe, S.2    Obertacke, U.3
  • 139
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NFκB induction by TNF, CD95 and IL-1
    • Malinin N.L., Boldin M.P., Kovalenko A.V., et al. MAP3K-related kinase involved in NFκB induction by TNF, CD95 and IL-1. Nature 1997, 385:540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3
  • 140
    • 0025728020 scopus 로고
    • A new superfamily of cell surface proteins related to the nerve growth factor receptor
    • Mallett S., Barclay A.N. A new superfamily of cell surface proteins related to the nerve growth factor receptor. Immunol. Today 1991, 12:220-223.
    • (1991) Immunol. Today , vol.12 , pp. 220-223
    • Mallett, S.1    Barclay, A.N.2
  • 141
    • 0023601773 scopus 로고
    • Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic β-cell cytotoxicity
    • Mandrup-Poulsen T., Bendtzen K., Dinarello C.A., et al. Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic β-cell cytotoxicity. J. Immunol. 1987, 139:4077-4082.
    • (1987) J. Immunol. , vol.139 , pp. 4077-4082
    • Mandrup-Poulsen, T.1    Bendtzen, K.2    Dinarello, C.A.3
  • 142
    • 0012752838 scopus 로고    scopus 로고
    • TNF2, a polymorphism of the tumour necrosis-α gene promoter, is a component of the celiac disease major histocompatibility complex haplotype
    • Manus R.M., Wilson A.G., Mansfield J., et al. TNF2, a polymorphism of the tumour necrosis-α gene promoter, is a component of the celiac disease major histocompatibility complex haplotype. Eur. J. Immunol. 1996, 26:2113-2118.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2113-2118
    • Manus, R.M.1    Wilson, A.G.2    Mansfield, J.3
  • 143
    • 0021750837 scopus 로고
    • Histocompatibility antigens in small cell carcinoma of the lung
    • Markman M., Braine H.G., Abeloff M.D. Histocompatibility antigens in small cell carcinoma of the lung. Cancer 1984, 54:2943-2945.
    • (1984) Cancer , vol.54 , pp. 2943-2945
    • Markman, M.1    Braine, H.G.2    Abeloff, M.D.3
  • 144
    • 0028812776 scopus 로고
    • How the glucocorticoids suppress immunity
    • Marx J. How the glucocorticoids suppress immunity. Science 1995, 270:232-233.
    • (1995) Science , vol.270 , pp. 232-233
    • Marx, J.1
  • 145
    • 0027319561 scopus 로고
    • Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose
    • Mattson M.P., Zhang Y., Bose S. Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp. Neurol. 1993, 121:1-13.
    • (1993) Exp. Neurol. , vol.121 , pp. 1-13
    • Mattson, M.P.1    Zhang, Y.2    Bose, S.3
  • 146
    • 0028483534 scopus 로고
    • Regulation of tumor necrosis factor-α processing by a metalloproteinase inhibitor
    • McGeehan G.M., Becherer J.D., Bast R.C., et al. Regulation of tumor necrosis factor-α processing by a metalloproteinase inhibitor. Nature 1994, 370:558-561.
    • (1994) Nature , vol.370 , pp. 558-561
    • McGeehan, G.M.1    Becherer, J.D.2    Bast, R.C.3
  • 147
    • 0028169333 scopus 로고
    • Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria
    • McGuire W., Hill A.V., Allsopp C.E., et al. Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria. Nature 1994, 371:508-510.
    • (1994) Nature , vol.371 , pp. 508-510
    • McGuire, W.1    Hill, A.V.2    Allsopp, C.E.3
  • 148
    • 0029865338 scopus 로고    scopus 로고
    • Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes
    • McManus R., Moloney M., Borton M., et al. Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes. Hum. Immunol. 1996, 45:24-31.
    • (1996) Hum. Immunol. , vol.45 , pp. 24-31
    • McManus, R.1    Moloney, M.2    Borton, M.3
  • 149
    • 0027200968 scopus 로고
    • Interleukin-1 receptor antibody (IL-1RAB) protection and treatment against lethal endotoxemia in mice
    • McNamara M.J., Norton J.A., Nauta R.J., et al. Interleukin-1 receptor antibody (IL-1RAB) protection and treatment against lethal endotoxemia in mice. J. Surg. Res. 1993, 54:316-321.
    • (1993) J. Surg. Res. , vol.54 , pp. 316-321
    • McNamara, M.J.1    Norton, J.A.2    Nauta, R.J.3
  • 150
    • 0027462845 scopus 로고
    • Cytokine regulation of neuronal differentiation of hippocampal progenitor cells
    • Mehler M.F., Rozental R., Dougherty M., et al. Cytokine regulation of neuronal differentiation of hippocampal progenitor cells. Nature 1993, 362:62-65.
    • (1993) Nature , vol.362 , pp. 62-65
    • Mehler, M.F.1    Rozental, R.2    Dougherty, M.3
  • 151
    • 0031262936 scopus 로고    scopus 로고
    • TNF is a brain-damaging cytokine in cerebral ischemia
    • Meistrell M., Botchkina G.I., Wang H., et al. TNF is a brain-damaging cytokine in cerebral ischemia. Shock 1997, 8:341-348.
    • (1997) Shock , vol.8 , pp. 341-348
    • Meistrell, M.1    Botchkina, G.I.2    Wang, H.3
  • 152
    • 0028067284 scopus 로고
    • HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection
    • Meyer C.G., Gallin M., Erttmann K.D., et al. HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection. Proc. Natl Acad. Sci. USA 1994, 91:7515-7519.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 7515-7519
    • Meyer, C.G.1    Gallin, M.2    Erttmann, K.D.3
  • 153
    • 0024437786 scopus 로고
    • Tumour necrosis factor in bronchopulmonary secretions of patients with adult respiratory distress syndrome
    • Millar A.B., Foley N.M., Singer M., et al. Tumour necrosis factor in bronchopulmonary secretions of patients with adult respiratory distress syndrome. Lancet 1989, ii:712-714.
    • (1989) Lancet , vol.2 , pp. 712-714
    • Millar, A.B.1    Foley, N.M.2    Singer, M.3
  • 154
    • 0027198002 scopus 로고
    • Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
    • Mohler K.M., Torrance D.S., Smith C.A., et al. Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists. J. Immunol. 1993, 151:1548-1561.
    • (1993) J. Immunol. , vol.151 , pp. 1548-1561
    • Mohler, K.M.1    Torrance, D.S.2    Smith, C.A.3
  • 155
    • 0023689026 scopus 로고
    • Endotoxin-stimulated human monocyte secretion of interleukin 1, tumour necrosis factor α, and prostaglandin E2 shows stable interindividual differences
    • Molvig J., Baek L., Christensen P., et al. Endotoxin-stimulated human monocyte secretion of interleukin 1, tumour necrosis factor α, and prostaglandin E2 shows stable interindividual differences. Scand. J. Immunol. 1988, 27:705-716.
    • (1988) Scand. J. Immunol. , vol.27 , pp. 705-716
    • Molvig, J.1    Baek, L.2    Christensen, P.3
  • 156
    • 0025191971 scopus 로고
    • GO protein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway
    • Moriarty T.M., Padrell E., Carty D.J., et al. GO protein as signal transducer in the pertussis toxin-sensitive phosphatidylinositol pathway. Nature 1990, 343:79-82.
    • (1990) Nature , vol.343 , pp. 79-82
    • Moriarty, T.M.1    Padrell, E.2    Carty, D.J.3
  • 157
    • 0024551090 scopus 로고
    • Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage
    • Moser R.B., Schleiffenbaum B., Groscurth P., et al. Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage. J. Clin. Invest. 1989, 83:444-455.
    • (1989) J. Clin. Invest. , vol.83 , pp. 444-455
    • Moser, R.B.1    Schleiffenbaum, B.2    Groscurth, P.3
  • 158
    • 8044250278 scopus 로고    scopus 로고
    • Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
    • Moss M.L., Jin S.L., Milla M.E., et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α. Nature 1997, 385:733-736.
    • (1997) Nature , vol.385 , pp. 733-736
    • Moss, M.L.1    Jin, S.L.2    Milla, M.E.3
  • 159
    • 0028799113 scopus 로고
    • A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
    • Mullberg J., Durie F.H., Otten-Evans C., et al. A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor. J. Immunol. 1995, 155:5198-5205.
    • (1995) J. Immunol. , vol.155 , pp. 5198-5205
    • Mullberg, J.1    Durie, F.H.2    Otten-Evans, C.3
  • 160
    • 0029003788 scopus 로고
    • PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid
    • Müller G., Ayoub M., Storz P., et al. PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid. EMBO J. 1995, 14:1961-1969.
    • (1995) EMBO J. , vol.14 , pp. 1961-1969
    • Müller, G.1    Ayoub, M.2    Storz, P.3
  • 161
    • 15844412409 scopus 로고    scopus 로고
    • FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
    • Muzio M., Chinnaiyan A.M., Kischkel F.C., et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 1996, 85:817-827.
    • (1996) Cell , vol.85 , pp. 817-827
    • Muzio, M.1    Chinnaiyan, A.M.2    Kischkel, F.C.3
  • 162
    • 0029738546 scopus 로고    scopus 로고
    • Induction of α-helix in the β-sheet protein tumor necrosis factor-α: acid-induced denaturation
    • Narhi L.O., Philo J.S., Li T., et al. Induction of α-helix in the β-sheet protein tumor necrosis factor-α: acid-induced denaturation. Biochemistry 1996, 35:11454-11460.
    • (1996) Biochemistry , vol.35 , pp. 11454-11460
    • Narhi, L.O.1    Philo, J.S.2    Li, T.3
  • 163
    • 0024520830 scopus 로고
    • Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human spetic shock
    • Natanson C., Eichenholz P.W., Danner R.L., et al. Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human spetic shock. J. Exp. Med. 1989, 169:823-832.
    • (1989) J. Exp. Med. , vol.169 , pp. 823-832
    • Natanson, C.1    Eichenholz, P.W.2    Danner, R.L.3
  • 164
    • 0031013545 scopus 로고    scopus 로고
    • Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway
    • Natoli G., Costanzo A., Ianni A., et al. Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway. Science 1997, 275:200-203.
    • (1997) Science , vol.275 , pp. 200-203
    • Natoli, G.1    Costanzo, A.2    Ianni, A.3
  • 165
    • 0022508582 scopus 로고
    • Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1
    • Nawroth P.P., Bank I., Handley D., et al. Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1. J. Exp. Med. 1986, 163:1363-1375.
    • (1986) J. Exp. Med. , vol.163 , pp. 1363-1375
    • Nawroth, P.P.1    Bank, I.2    Handley, D.3
  • 166
    • 0023916785 scopus 로고
    • The antitumor function of tumor necrosis factor (TNF). II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma
    • North R.J., Havell E.A. The antitumor function of tumor necrosis factor (TNF). II. Analysis of the role of endogenous TNF in endotoxin-induced hemorrhagic necrosis and regression of an established sarcoma. J. Exp. Med. 1988, 167:1086-1099.
    • (1988) J. Exp. Med. , vol.167 , pp. 1086-1099
    • North, R.J.1    Havell, E.A.2
  • 167
    • 0024352283 scopus 로고
    • Hepatic arterial infusion of human recombinant tumor necrosis factor-α. An experimental study in dogs
    • Ohkawa S., Wright K.C., Mahajan H., et al. Hepatic arterial infusion of human recombinant tumor necrosis factor-α. An experimental study in dogs. Cancer 1989, 63:2096-2102.
    • (1989) Cancer , vol.63 , pp. 2096-2102
    • Ohkawa, S.1    Wright, K.C.2    Mahajan, H.3
  • 168
    • 0030185947 scopus 로고    scopus 로고
    • Regulation of pulp cell matrix metalloproteinase production by cytokines and lipopolysaccharides
    • Panagakos F.S., O'Boskey J.F., Rodriguez E. Regulation of pulp cell matrix metalloproteinase production by cytokines and lipopolysaccharides. J. Endod. 1996, 22:358-361.
    • (1996) J. Endod. , vol.22 , pp. 358-361
    • Panagakos, F.S.1    O'Boskey, J.F.2    Rodriguez, E.3
  • 169
    • 0023796459 scopus 로고
    • Low degree of DNA polymorphism in the HIA-linked lymphotoxin (tumour necrosis factor β) gene
    • Partanen J., Koskimies S. Low degree of DNA polymorphism in the HIA-linked lymphotoxin (tumour necrosis factor β) gene. Scand. J. Immunol. 1988, 28:313-316.
    • (1988) Scand. J. Immunol. , vol.28 , pp. 313-316
    • Partanen, J.1    Koskimies, S.2
  • 170
    • 0038985463 scopus 로고    scopus 로고
    • Stress-induced apoptosis and the sphingomyelin pathway
    • Pena L.A., Fuks Z., Kolesnick R. Stress-induced apoptosis and the sphingomyelin pathway. Biochem. Pharmacol. 1997, 53:615-621.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 615-621
    • Pena, L.A.1    Fuks, Z.2    Kolesnick, R.3
  • 171
    • 0025827590 scopus 로고
    • A tumor necrosis factor (TNF) receptor-IGG heavy chain chimeric protein as a bivalent antagonist of TNF activity
    • Peppel K., Crawford D., Beutler B. A tumor necrosis factor (TNF) receptor-IGG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J. Exp. Med. 1991, 174:1483-1489.
    • (1991) J. Exp. Med. , vol.174 , pp. 1483-1489
    • Peppel, K.1    Crawford, D.2    Beutler, B.3
  • 172
    • 0027297663 scopus 로고
    • Mice deficient for the 55 kD tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection
    • Pfeffer K., Matsuyama T., Kundig T.M., et al. Mice deficient for the 55 kD tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993, 73:457-467.
    • (1993) Cell , vol.73 , pp. 457-467
    • Pfeffer, K.1    Matsuyama, T.2    Kundig, T.M.3
  • 173
    • 0034254553 scopus 로고    scopus 로고
    • TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha
    • Piecyk M., Wax S., Beck A.R., et al. TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J. 2000, 19:4154-4163.
    • (2000) EMBO J. , vol.19 , pp. 4154-4163
    • Piecyk, M.1    Wax, S.2    Beck, A.R.3
  • 174
    • 0028105830 scopus 로고
    • Prediction of long-term mortality inpatients with rheumatoid arthritis according to simple questionnaire and joint count measures
    • Pincus T., Brooks R.H., Callahan L.F. Prediction of long-term mortality inpatients with rheumatoid arthritis according to simple questionnaire and joint count measures. Ann. Intern. Med. 1994, 120:26-34.
    • (1994) Ann. Intern. Med. , vol.120 , pp. 26-34
    • Pincus, T.1    Brooks, R.H.2    Callahan, L.F.3
  • 175
    • 0025903428 scopus 로고
    • Immunoregulators in the nervous system
    • Plata-Salaman C.R. Immunoregulators in the nervous system. Neurosci. Biobehav. Rev. 1991, 15:185-215.
    • (1991) Neurosci. Biobehav. Rev. , vol.15 , pp. 185-215
    • Plata-Salaman, C.R.1
  • 176
    • 0027397580 scopus 로고
    • Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus
    • Pociot F., Briant L., Jongeneel C.V., et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur. J. Immunol. 1993, 23:224-231.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 224-231
    • Pociot, F.1    Briant, L.2    Jongeneel, C.V.3
  • 177
    • 0027434873 scopus 로고
    • No independent association between a tumor necrosis factor-α promoter region polymorphism and insulin-dependent diabetes mellitus
    • Pociot F., Wilson A.G., Nerup J., et al. No independent association between a tumor necrosis factor-α promoter region polymorphism and insulin-dependent diabetes mellitus. Eur. J. Immunol. 1993, 23:3050-3053.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3050-3053
    • Pociot, F.1    Wilson, A.G.2    Nerup, J.3
  • 178
    • 0034045545 scopus 로고    scopus 로고
    • TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus
    • Rood M.J., van Krugten M.V., Zanelli E., et al. TNF-308A and HLA-DR3 alleles contribute independently to susceptibility to systemic lupus erythematosus. Arthritis Rheum. 2000, 43:129-134.
    • (2000) Arthritis Rheum. , vol.43 , pp. 129-134
    • Rood, M.J.1    van Krugten, M.V.2    Zanelli, E.3
  • 179
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NFκB by TNF receptor 2 and CD40
    • Rothe M., Sarma V., Dixit V.M., et al. TRAF2-mediated activation of NFκB by TNF receptor 2 and CD40. Science 1995, 269:1424-1427.
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3
  • 180
    • 0026080801 scopus 로고
    • Thalido-mide selectively inhibits tumor necrosis factor α production by stimulated human monocytes
    • Sampaio E.P., Sarno E.N., Galilly R., et al. Thalido-mide selectively inhibits tumor necrosis factor α production by stimulated human monocytes. J. Exp. Med. 1991, 173:699-703.
    • (1991) J. Exp. Med. , vol.173 , pp. 699-703
    • Sampaio, E.P.1    Sarno, E.N.2    Galilly, R.3
  • 181
    • 0033125226 scopus 로고    scopus 로고
    • Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety
    • Sandborn W.J., Hanauer S.B. Antitumor necrosis factor therapy for inflammatory bowel disease: a review of agents, pharmacology, clinical results, and safety. Inflamm. Bowel Dis. 1999, 5:119-133.
    • (1999) Inflamm. Bowel Dis. , vol.5 , pp. 119-133
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 182
    • 0022578656 scopus 로고
    • Actions of tumor necrosis factor on cultured vascular endothelial cells: morphologic modulation, growth inhibition, and cytotoxicity
    • Sato N., Goto T., Haranaka K., et al. Actions of tumor necrosis factor on cultured vascular endothelial cells: morphologic modulation, growth inhibition, and cytotoxicity. J. Natl Cancer Inst. 1986, 76:1113-1121.
    • (1986) J. Natl Cancer Inst. , vol.76 , pp. 1113-1121
    • Sato, N.1    Goto, T.2    Haranaka, K.3
  • 183
    • 0029913929 scopus 로고    scopus 로고
    • Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients
    • Sato Y., Koshita Y., Hirayama M., et al. Augmented antitumor effects of killer cells induced by tumor necrosis factor gene-transduced autologous tumor cells from gastrointestinal cancer patients. Hum Gene Ther. 1996, 7:1895-1905.
    • (1996) Hum Gene Ther. , vol.7 , pp. 1895-1905
    • Sato, Y.1    Koshita, Y.2    Hirayama, M.3
  • 184
    • 0025138735 scopus 로고
    • The role of cytokines in the generation of inflammation and tissue damage in experimental Gram-positive meningitis
    • Saukkonen K., Sande S., Cioffe C., et al. The role of cytokines in the generation of inflammation and tissue damage in experimental Gram-positive meningitis. J. Exp. Med. 1990, 171:439-448.
    • (1990) J. Exp. Med. , vol.171 , pp. 439-448
    • Saukkonen, K.1    Sande, S.2    Cioffe, C.3
  • 185
    • 0028879819 scopus 로고
    • Role of transcriptional activation of IκB α in mediation of immunosuppression by glucocorticoids
    • Scheinman R.I., Cogswell P.C., Lofquist A.K., et al. Role of transcriptional activation of IκB α in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3
  • 186
    • 0026602180 scopus 로고
    • Clinical and biologic effects of combination therapy with γ-interferon and tumor necrosis factor
    • Schiller J.H., Win P.L., Storer B., et al. Clinical and biologic effects of combination therapy with γ-interferon and tumor necrosis factor. Cancer 1992, 69:562-571.
    • (1992) Cancer , vol.69 , pp. 562-571
    • Schiller, J.H.1    Win, P.L.2    Storer, B.3
  • 187
    • 0026458406 scopus 로고
    • TNF activates NFκB by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown
    • Schutze S., Potthoff K., Machleidt T., et al. TNF activates NFκB by phosphatidylcholine-specific phospholipase C-induced 'acidic' sphingomyelin breakdown. Cell 1992, 71:765-776.
    • (1992) Cell , vol.71 , pp. 765-776
    • Schutze, S.1    Potthoff, K.2    Machleidt, T.3
  • 188
    • 0034467037 scopus 로고    scopus 로고
    • Anti-TNF-alpha therapy as a clinical intervention for periprosthetic osteolysis
    • Schwarz E.M., Looney R.J., O'Keefe R.J. Anti-TNF-alpha therapy as a clinical intervention for periprosthetic osteolysis. Arthritis Res. 2000, 2:165-168.
    • (2000) Arthritis Res. , vol.2 , pp. 165-168
    • Schwarz, E.M.1    Looney, R.J.2    O'Keefe, R.J.3
  • 189
    • 0024332475 scopus 로고
    • Purification and biologic characterization of a specific tumor necrosis factor α inhibitor
    • Seckinger P., Isaaz S., Dayer J.M. Purification and biologic characterization of a specific tumor necrosis factor α inhibitor. J. Biol. Chem. 1989, 264:11966-11973.
    • (1989) J. Biol. Chem. , vol.264 , pp. 11966-11973
    • Seckinger, P.1    Isaaz, S.2    Dayer, J.M.3
  • 190
    • 0035002214 scopus 로고    scopus 로고
    • Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFα monoclonal antibody and by pentoxiphylline
    • Segal R., Dayan M., Zinger H., et al. Suppression of experimental systemic lupus erythematosus (SLE) in mice via TNF inhibition by an anti-TNFα monoclonal antibody and by pentoxiphylline. Lupus 2001, 10:23-31.
    • (2001) Lupus , vol.10 , pp. 23-31
    • Segal, R.1    Dayan, M.2    Zinger, H.3
  • 191
    • 0038035591 scopus 로고    scopus 로고
    • Stress-induced apoptosis is not mediated by endolysosomal ceramide
    • Ségui B., Bezombes C., Uro-Coste E., et al. Stress-induced apoptosis is not mediated by endolysosomal ceramide. FASEB J. 2000, 14:36-47.
    • (2000) FASEB J. , vol.14 , pp. 36-47
    • Ségui, B.1    Bezombes, C.2    Uro-Coste, E.3
  • 192
    • 0025092159 scopus 로고
    • Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor
    • Selmaj K.W., Farooq M., Norton W.T., et al. Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J. Immunol. 1990, 144:129-135.
    • (1990) J. Immunol. , vol.144 , pp. 129-135
    • Selmaj, K.W.1    Farooq, M.2    Norton, W.T.3
  • 193
    • 0034186168 scopus 로고    scopus 로고
    • Anti-TNF therapy for Crohn's disease: a perspective (infliximab is not the drug we have been waiting for)
    • Shanahan F. Anti-TNF therapy for Crohn's disease: a perspective (infliximab is not the drug we have been waiting for). Inflamm. Bowel Dis. 2000, 6:137-139.
    • (2000) Inflamm. Bowel Dis. , vol.6 , pp. 137-139
    • Shanahan, F.1
  • 194
    • 0023058975 scopus 로고
    • A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation
    • Shaw G., Kamen R. A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 1986, 46:659-667.
    • (1986) Cell , vol.46 , pp. 659-667
    • Shaw, G.1    Kamen, R.2
  • 195
    • 0028120813 scopus 로고
    • The study of tumor necrosis factor β gene polymorphism in lung cancer patients
    • Shimura T., Hagihara M., Takebe K., et al. The study of tumor necrosis factor β gene polymorphism in lung cancer patients. Cancer 1994, 73:1184-1188.
    • (1994) Cancer , vol.73 , pp. 1184-1188
    • Shimura, T.1    Hagihara, M.2    Takebe, K.3
  • 196
    • 0027375872 scopus 로고
    • The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells
    • Shingu M., Nagai Y., Isayama T., et al. The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells. Clin. Exp. Immunol. 1993, 94:145-149.
    • (1993) Clin. Exp. Immunol. , vol.94 , pp. 145-149
    • Shingu, M.1    Nagai, Y.2    Isayama, T.3
  • 197
    • 0037085476 scopus 로고    scopus 로고
    • A high affinity HSF-1 binding site in the 5'-untranslated region of the murine tumor necrosis factor-(alpha) gene is a transcriptional repressor
    • Singh I.S., He J.R., Calderwood S., et al. A high affinity HSF-1 binding site in the 5'-untranslated region of the murine tumor necrosis factor-(alpha) gene is a transcriptional repressor. J. Biol. Chem. 2001, 15:4981-4988.
    • (2001) J. Biol. Chem. , vol.15 , pp. 4981-4988
    • Singh, I.S.1    He, J.R.2    Calderwood, S.3
  • 198
    • 0023882543 scopus 로고
    • Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts
    • Silver I.A., Murrills R.J., Etherington D.J. Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp. Cell Res. 1988, 175:266-276.
    • (1988) Exp. Cell Res. , vol.175 , pp. 266-276
    • Silver, I.A.1    Murrills, R.J.2    Etherington, D.J.3
  • 199
    • 0023192180 scopus 로고
    • The active form of tumor necrosis factor is a trimer
    • Smith R.A., Baglioni C. The active form of tumor necrosis factor is a trimer. J. Biol. Chem. 1987, 262:6951-6954.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6951-6954
    • Smith, R.A.1    Baglioni, C.2
  • 200
    • 0026444303 scopus 로고
    • Characterization of TNF receptors
    • Smith R.A., Baglioni C. Characterization of TNF receptors. Immunol. Ser. 1992, 56:131-147.
    • (1992) Immunol. Ser. , vol.56 , pp. 131-147
    • Smith, R.A.1    Baglioni, C.2
  • 201
    • 0024492512 scopus 로고
    • Evidence for a primary association of celiac disease to a particular HLA-DQα/β heterodimer
    • Sollid L.M., Markussen G., Ek J., et al. Evidence for a primary association of celiac disease to a particular HLA-DQα/β heterodimer. J. Exp. Med. 1989, 169:345-350.
    • (1989) J. Exp. Med. , vol.169 , pp. 345-350
    • Sollid, L.M.1    Markussen, G.2    Ek, J.3
  • 202
    • 0027353039 scopus 로고
    • Sphingomyelinases
    • Spence M.W. Sphingomyelinases. Adv. Lipid Res. 1993, 26:3-23.
    • (1993) Adv. Lipid Res. , vol.26 , pp. 3-23
    • Spence, M.W.1
  • 203
    • 0029054725 scopus 로고
    • RIP: a novel protein containing a death domain that interacts with FAS/APO-1 (CD95) in yeast and causes cell death
    • Stanger B.Z., Leder P., Lee T.H., et al. RIP: a novel protein containing a death domain that interacts with FAS/APO-1 (CD95) in yeast and causes cell death. Cell 1995, 81:513-523.
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.H.3
  • 204
    • 0023686040 scopus 로고
    • Granulocyte depletion prevents tumor necrosis factor-mediated acute lung injury in guinea pigs
    • Stephens K.E., Ishizaka A., Wu Z.H., et al. Granulocyte depletion prevents tumor necrosis factor-mediated acute lung injury in guinea pigs. Am. Rev. Respir. Dis. 1988, 138:1300-1307.
    • (1988) Am. Rev. Respir. Dis. , vol.138 , pp. 1300-1307
    • Stephens, K.E.1    Ishizaka, A.2    Wu, Z.H.3
  • 205
    • 0029922017 scopus 로고    scopus 로고
    • A genomic polymorphims within the tumor necrosis factor locus influences plasma tumor necrosis factor-a concentrations and outcome of patients with severe sepsis
    • Stuber F., Petersen M., Bokelmann F., et al. A genomic polymorphims within the tumor necrosis factor locus influences plasma tumor necrosis factor-a concentrations and outcome of patients with severe sepsis. Crit. Care Med. 1996, 24:381-384.
    • (1996) Crit. Care Med. , vol.24 , pp. 381-384
    • Stuber, F.1    Petersen, M.2    Bokelmann, F.3
  • 206
    • 0024342856 scopus 로고
    • The cardiovascular response of normal humans to the administration of endotoxin
    • Suffredini A.F., Fromm R.E., Parker M.M., et al. The cardiovascular response of normal humans to the administration of endotoxin. N. Engl J. Med. 1989, 321:280-287.
    • (1989) N. Engl J. Med. , vol.321 , pp. 280-287
    • Suffredini, A.F.1    Fromm, R.E.2    Parker, M.M.3
  • 207
    • 0022382737 scopus 로고
    • Recombinat human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro
    • Sugarman B.J., Aggarwal B.B., Hass P.E., et al. Recombinat human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science 1985, 230:943-945.
    • (1985) Science , vol.230 , pp. 943-945
    • Sugarman, B.J.1    Aggarwal, B.B.2    Hass, P.E.3
  • 208
    • 0026072837 scopus 로고
    • The two different receptors for tumor necrosis factor mediate distinct cellular responses
    • Tartaglia L.A., Weber R.F., Figari I.S., et al. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl Acad. Sci. USA 1991, 88:9292-9296.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 9292-9296
    • Tartaglia, L.A.1    Weber, R.F.2    Figari, I.S.3
  • 209
    • 0027275490 scopus 로고
    • A novel domain within the 55 kD TNF receptor signals cell death
    • Tartaglia L.A., Ayres T.M., Wong G.H., et al. A novel domain within the 55 kD TNF receptor signals cell death. Cell 1993, 74:845-853.
    • (1993) Cell , vol.74 , pp. 845-853
    • Tartaglia, L.A.1    Ayres, T.M.2    Wong, G.H.3
  • 210
    • 0027301244 scopus 로고
    • Ligand passing: the 75-kDA tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor
    • Tartaglia L.A., Pennica D., Goeddel D.V. Ligand passing: the 75-kDA tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. J. Biol. Chem. 1993, 268:18542-18548.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18542-18548
    • Tartaglia, L.A.1    Pennica, D.2    Goeddel, D.V.3
  • 211
    • 0035012652 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapies
    • Taylor P.C. Anti-tumor necrosis factor therapies. Curr. Opin. Rheumatol. 2001, 13:164-169.
    • (2001) Curr. Opin. Rheumatol. , vol.13 , pp. 164-169
    • Taylor, P.C.1
  • 212
    • 0031561534 scopus 로고    scopus 로고
    • Neuroscience. More than just frequency detectors?
    • Thomson A.M. Neuroscience. More than just frequency detectors?. Science 1997, 275:179-180.
    • (1997) Science , vol.275 , pp. 179-180
    • Thomson, A.M.1
  • 213
    • 0031626512 scopus 로고    scopus 로고
    • Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493
    • Tracey K.J. Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493. Prog. Clin. Biol. Res. 1998, 397:335-343.
    • (1998) Prog. Clin. Biol. Res. , vol.397 , pp. 335-343
    • Tracey, K.J.1
  • 214
    • 0025003076 scopus 로고
    • Metabolic responses to cachectin/TNF. A brief review
    • Tracey K.J., Cerami A. Metabolic responses to cachectin/TNF. A brief review. Ann. NY Acad. Sci. 1990, 587:325-331.
    • (1990) Ann. NY Acad. Sci. , vol.587 , pp. 325-331
    • Tracey, K.J.1    Cerami, A.2
  • 215
    • 0028244816 scopus 로고
    • Tumor necrosis factor: a pleiotropic cytokine and therapeutic target
    • Tracey K.J., Cerami A. Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 1994, 45:491-503.
    • (1994) Annu. Rev. Med. , vol.45 , pp. 491-503
    • Tracey, K.J.1    Cerami, A.2
  • 216
    • 0023028369 scopus 로고
    • Shock and tissue injury induced by recombinant human cachectin
    • Tracey K.J., Beutler B., Lowry S.F., et al. Shock and tissue injury induced by recombinant human cachectin. Science 1986, 234:470-474.
    • (1986) Science , vol.234 , pp. 470-474
    • Tracey, K.J.1    Beutler, B.2    Lowry, S.F.3
  • 217
    • 0022492412 scopus 로고
    • Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential
    • Tracey K.J., Lowry S.F., Beutler B., et al. Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential. J. Exp. Med. 1986, 164:1368-1373.
    • (1986) J. Exp. Med. , vol.164 , pp. 1368-1373
    • Tracey, K.J.1    Lowry, S.F.2    Beutler, B.3
  • 218
    • 0023491364 scopus 로고
    • Anticachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
    • Tracey K.J., Fong Y., Hesse D.G., et al. Anticachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 1987, 330:662-664.
    • (1987) Nature , vol.330 , pp. 662-664
    • Tracey, K.J.1    Fong, Y.2    Hesse, D.G.3
  • 219
    • 0023183621 scopus 로고
    • Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog
    • Tracey K.J., Lowry S.F., Fahey T.J., et al. Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. Surg. Gynecol. Obstet. 1987, 164:415-422.
    • (1987) Surg. Gynecol. Obstet. , vol.164 , pp. 415-422
    • Tracey, K.J.1    Lowry, S.F.2    Fahey, T.J.3
  • 220
    • 0023916786 scopus 로고
    • Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation
    • Tracey K.J., Wei H., Manogue K.R., et al. Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation. J. Exp. Med. 1988, 167:1211-1227.
    • (1988) J. Exp. Med. , vol.167 , pp. 1211-1227
    • Tracey, K.J.1    Wei, H.2    Manogue, K.R.3
  • 221
    • 0024513152 scopus 로고
    • Cachectin/tumour necrosis factor
    • Tracey K.J., Vlassara H., Cerami A. Cachectin/tumour necrosis factor. Lancet 1989, i:1122-1126.
    • (1989) Lancet , vol.1 , pp. 1122-1126
    • Tracey, K.J.1    Vlassara, H.2    Cerami, A.3
  • 222
    • 0029837669 scopus 로고    scopus 로고
    • Cell-type-specific regulation of the human tumor necrosis factor-α gene in B cells and T cells by NFATP and ATF-2/Jun
    • Tsai E.Y., Yie J., Thanos D., et al. Cell-type-specific regulation of the human tumor necrosis factor-α gene in B cells and T cells by NFATP and ATF-2/Jun. Mol. Cell Biol. 1996, 16:5232-5244.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5232-5244
    • Tsai, E.Y.1    Yie, J.2    Thanos, D.3
  • 223
    • 0035491457 scopus 로고    scopus 로고
    • Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test
    • Tsuchiya N., Kawasaki A., Tsao B.P., et al. Analysis of the association of HLA-DRB1, TNFalpha promoter and TNFR2 (TNFRSF1B) polymorphisms with SLE using transmission disequilibrium test. Genes Immun. 2001, 2:317-322.
    • (2001) Genes Immun. , vol.2 , pp. 317-322
    • Tsuchiya, N.1    Kawasaki, A.2    Tsao, B.P.3
  • 224
    • 0029058648 scopus 로고
    • Molecular design of hybrid tumour necrosis factor-α with polyethylene glycol increases its anti-tumour potency
    • Tsutsumi Y., Kihira T., Tsunoda S., et al. Molecular design of hybrid tumour necrosis factor-α with polyethylene glycol increases its anti-tumour potency. Br. J. Cancer 1995, 71:963-968.
    • (1995) Br. J. Cancer , vol.71 , pp. 963-968
    • Tsutsumi, Y.1    Kihira, T.2    Tsunoda, S.3
  • 225
    • 0027151876 scopus 로고
    • Highly informative typing of the human TNF locus using six adjacent polymorphic markers
    • Udalova I.A., Nedospasov S.A., Webb G.C., et al. Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomics 1993, 16:180-186.
    • (1993) Genomics , vol.16 , pp. 180-186
    • Udalova, I.A.1    Nedospasov, S.A.2    Webb, G.C.3
  • 226
    • 0029992609 scopus 로고    scopus 로고
    • Suppression of TNF-α-induced apoptosis by NFκB
    • Van Antwerp D.J., Martin S.J., Kafri T., et al. Suppression of TNF-α-induced apoptosis by NFκB. Science 1996, 274:787-789.
    • (1996) Science , vol.274 , pp. 787-789
    • Van Antwerp, D.J.1    Martin, S.J.2    Kafri, T.3
  • 227
    • 0032833505 scopus 로고    scopus 로고
    • Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells
    • van der Goot F.G., Pugin J., Hribar M., et al. Membrane interaction of TNF is not sufficient to trigger increase in membrane conductance in mammalian cells. FEBS Lett. 1999, 460:107-111.
    • (1999) FEBS Lett. , vol.460 , pp. 107-111
    • van der Goot, F.G.1    Pugin, J.2    Hribar, M.3
  • 228
    • 0035513853 scopus 로고    scopus 로고
    • Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus
    • van der Linden M.W., van der Slik A.R., Zanelli E., et al. Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus. Genes Immun. 2001, 2:373-380.
    • (2001) Genes Immun. , vol.2 , pp. 373-380
    • van der Linden, M.W.1    van der Slik, A.R.2    Zanelli, E.3
  • 229
    • 0029192212 scopus 로고
    • Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense?
    • (editorial)
    • van der Poll T., Lowry S.F. Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense?. Shock 1995, 3:1-12. (editorial).
    • (1995) Shock , vol.3 , pp. 1-12
    • van der Poll, T.1    Lowry, S.F.2
  • 230
    • 0027392199 scopus 로고
    • Human TNF mutants with selective activity on the p55 receptor
    • Van Ostade X., Vandenabeele P., Everaerdt B., et al. Human TNF mutants with selective activity on the p55 receptor. Nature 1993, 361:266-269.
    • (1993) Nature , vol.361 , pp. 266-269
    • Van Ostade, X.1    Vandenabeele, P.2    Everaerdt, B.3
  • 231
    • 0028203560 scopus 로고
    • A human tumor necrosis factor (TNF) a mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon
    • Van Zee K.J., Stackpole S.A., Montegut W.J., et al. A human tumor necrosis factor (TNF) a mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon. J. Exp. Med. 1994, 179:1185-1191.
    • (1994) J. Exp. Med. , vol.179 , pp. 1185-1191
    • Van Zee, K.J.1    Stackpole, S.A.2    Montegut, W.J.3
  • 232
    • 0035892750 scopus 로고    scopus 로고
    • In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL
    • Via C.S., Shustov A., Rus V., et al. In vivo neutralization of TNF-alpha promotes humoral autoimmunity by preventing the induction of CTL. J. Immunol. 2001, 167:6821-6826.
    • (2001) J. Immunol. , vol.167 , pp. 6821-6826
    • Via, C.S.1    Shustov, A.2    Rus, V.3
  • 233
    • 0024529891 scopus 로고
    • The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1. and fatal outcome
    • Waage A., Brandtzaeg P., Halstensen A., et al. The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1. and fatal outcome. J. Exp. Med. 1989, 169:333-338.
    • (1989) J. Exp. Med. , vol.169 , pp. 333-338
    • Waage, A.1    Brandtzaeg, P.2    Halstensen, A.3
  • 234
    • 0029858387 scopus 로고    scopus 로고
    • TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NFκB
    • Wang C.Y., Mayo M.W., Baldwin A.S. TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NFκB. Science 1996, 274:784-787.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 235
    • 0033611472 scopus 로고    scopus 로고
    • A trial of etanercept, a recombinant tumor necrosis factor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
    • Weinblatt M.E., Kremer J.M., Bankhurst A.D., et al. A trial of etanercept, a recombinant tumor necrosis factor: Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. N. Engl J. Med. 1999, 340:253-259.
    • (1999) N. Engl J. Med. , vol.340 , pp. 253-259
    • Weinblatt, M.E.1    Kremer, J.M.2    Bankhurst, A.D.3
  • 236
    • 0023771690 scopus 로고
    • Major histocompatibility complex extended haplotypes in systemic lupus erythematosus
    • Welch T.R., Beischel L.S., Balakrishnan K., et al. Major histocompatibility complex extended haplotypes in systemic lupus erythematosus. Dis. Markers 1988, 6:247-255.
    • (1988) Dis. Markers , vol.6 , pp. 247-255
    • Welch, T.R.1    Beischel, L.S.2    Balakrishnan, K.3
  • 237
    • 0028108015 scopus 로고
    • Functional dichotomy of neutral and acidic sphin-gomyelinases in tumor necrosis factor signaling
    • Weegmann K., Schutze S., Machleidt T., et al. Functional dichotomy of neutral and acidic sphin-gomyelinases in tumor necrosis factor signaling. Cell 1994, 78:1005-1015.
    • (1994) Cell , vol.78 , pp. 1005-1015
    • Weegmann, K.1    Schutze, S.2    Machleidt, T.3
  • 238
    • 0027534914 scopus 로고
    • An allelic polymorphism within the human tumor necrosis factor-α promoter region is strongly associated with HLA A1, B8, and DR3 alleles
    • Wilson A.G., de Vries N., Pociot F., et al. An allelic polymorphism within the human tumor necrosis factor-α promoter region is strongly associated with HLA A1, B8, and DR3 alleles. J. Exp. Med. 1993, 177:557-560.
    • (1993) J. Exp. Med. , vol.177 , pp. 557-560
    • Wilson, A.G.1    de Vries, N.2    Pociot, F.3
  • 239
    • 0028157286 scopus 로고
    • A genetic association between systemic lupus erythematosus and tumor necrosis factor-α
    • Wilson A.G., Gordon C., Di Giovine F.S., et al. A genetic association between systemic lupus erythematosus and tumor necrosis factor-α. Eur. J. Immunol. 1994, 24:191-195.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 191-195
    • Wilson, A.G.1    Gordon, C.2    Di Giovine, F.S.3
  • 240
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor-α promoter on transcriptional activation
    • Wilson A.G., Symons J.A., McDowell T.L., et al. Effects of a polymorphism in the human tumor necrosis factor-α promoter on transcriptional activation. Proc. Natl Acad. Sci. USA 1997, 94:3195-3199.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 3195-3199
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3
  • 241
    • 0028984578 scopus 로고
    • Activation of p42MAPK/ERK2 following engagement of tumor necrosis factor receptor CD120A (p55) in mouse macrophages
    • Winston B.W., Riches D.X. Activation of p42MAPK/ERK2 following engagement of tumor necrosis factor receptor CD120A (p55) in mouse macrophages. J. Immunol. 1995, 155:1525-1533.
    • (1995) J. Immunol. , vol.155 , pp. 1525-1533
    • Winston, B.W.1    Riches, D.X.2
  • 242
    • 0024202127 scopus 로고
    • Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism
    • Wong G.H., Goeddel D.V. Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism. Science 1988, 242:941-944.
    • (1988) Science , vol.242 , pp. 941-944
    • Wong, G.H.1    Goeddel, D.V.2
  • 243
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Dickens M., Raingeaud J., et al. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995, 270:1326-1331.
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3
  • 244
    • 0027483722 scopus 로고
    • Cellular basis for the negative inotropic effects of tumor necrosis factor-α in the adult mammalian heart
    • Yokoyama T., Vaca L., Rossen R.D., et al. Cellular basis for the negative inotropic effects of tumor necrosis factor-α in the adult mammalian heart. J. Clin. Invest. 1993, 92:2303-2312.
    • (1993) J. Clin. Invest. , vol.92 , pp. 2303-2312
    • Yokoyama, T.1    Vaca, L.2    Rossen, R.D.3
  • 245
    • 0023212746 scopus 로고
    • Different and synergistic actions of human tumor necrosis factor and interferon-γ in damage of liposome membranes
    • Yoshimura T., Sone S. Different and synergistic actions of human tumor necrosis factor and interferon-γ in damage of liposome membranes. J. Biol. Chem. 1987, 262:4597-4601.
    • (1987) J. Biol. Chem. , vol.262 , pp. 4597-4601
    • Yoshimura, T.1    Sone, S.2
  • 246
    • 4243199148 scopus 로고
    • A novel MAP kinase regulates the production of IL-1 and TNF in LPS activated human monocytes
    • Young P., McDonnell P., Laydon J., et al. A novel MAP kinase regulates the production of IL-1 and TNF in LPS activated human monocytes. Cytokine 1994, 6:564.
    • (1994) Cytokine , vol.6 , pp. 564
    • Young, P.1    McDonnell, P.2    Laydon, J.3
  • 247
    • 0030965838 scopus 로고    scopus 로고
    • Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells
    • Zhang M., Caragine T., Wang K., et al. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells. J. Exp. Med. 1997, 185:1759-1768.
    • (1997) J. Exp. Med. , vol.185 , pp. 1759-1768
    • Zhang, M.1    Caragine, T.2    Wang, K.3
  • 248
    • 0027104539 scopus 로고
    • Site-directed mutational analysis of human tumor necrosis factor-α receptor binding site and structure-functional relationship
    • Zhang X.M., Weber I., Chen M.J. Site-directed mutational analysis of human tumor necrosis factor-α receptor binding site and structure-functional relationship. J. Biol. Chem. 1992, 267:24069-24075.
    • (1992) J. Biol. Chem. , vol.267 , pp. 24069-24075
    • Zhang, X.M.1    Weber, I.2    Chen, M.J.3
  • 249
    • 0029112253 scopus 로고
    • Induction of apoptosis in mature T cells by tumour necrosis factor
    • Zheng L., Fisher G., Miller R.E., et al. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature 1995, 377:348-351.
    • (1995) Nature , vol.377 , pp. 348-351
    • Zheng, L.1    Fisher, G.2    Miller, R.E.3
  • 250
    • 0034660627 scopus 로고    scopus 로고
    • Regulation of TNF expression by multiple mitogen-activated protein kinase pathways
    • Zhu W., Downey J.S., Gu J., et al. Regulation of TNF expression by multiple mitogen-activated protein kinase pathways. J. Immunol. 2000, 164:6349-6358.
    • (2000) J. Immunol. , vol.164 , pp. 6349-6358
    • Zhu, W.1    Downey, J.S.2    Gu, J.3
  • 251
    • 0024582830 scopus 로고
    • Oxidative damage in murine tumor cells treated in vitro by recombinant human tumor necrosis factor
    • Zimmerman R.J., Chan A., Leadon S.A. Oxidative damage in murine tumor cells treated in vitro by recombinant human tumor necrosis factor. Cancer Res. 1989, 49:1644-1648.
    • (1989) Cancer Res. , vol.49 , pp. 1644-1648
    • Zimmerman, R.J.1    Chan, A.2    Leadon, S.A.3
  • 252
    • 0028900073 scopus 로고
    • The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation
    • Zubiaga A.M., Belasco J.G., Greenberg M.E. The nonamer UUAUUUAUU is the key AU-rich sequence motif that mediates mRNA degradation. Mol. Cell Biol. 1995, 15:2219-2230.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 2219-2230
    • Zubiaga, A.M.1    Belasco, J.G.2    Greenberg, M.E.3
  • 253
    • 0035514416 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with systemic lupus erythematosus (SLE)
    • Zuniga J., Vargas-Alarcon G., Hernandez-Pacheco G., et al. tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with systemic lupus erythematosus (SLE). Genes Immun. 2001, 2:363-366.
    • (2001) Genes Immun. , vol.2 , pp. 363-366
    • Zuniga, J.1    Vargas-Alarcon, G.2    Hernandez-Pacheco, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.