High resolution crystal structure of a human tumor necrosis factor-α mutant with low systemic toxicity

Journal of Biological Chemistry

Volumn 273, Issue 4, 1998, Pages 2153-2160

  Cha, Sun Shin ^a   Kim, Jeong Sun ^a   Cho, Hyun Soo ^a   Shin, Nam Kyu ^b   Jeong, Woojin ^b   Shin, Hang Cheol ^b   Kim, Yeoun Jin ^a   Hahn, Jong Boon ^a   Oh, Byung Ha ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Hanhyo Institute of Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; CYTOKINE PRODUCTION; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROPHILICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; TOXICITY TESTING;

ANIMALS; CELL SURVIVAL; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DACTINOMYCIN; HALF-LIFE; HEAT; HUMANS; HYDROGEN-ION CONCENTRATION; L CELLS (CELL LINE); MICE; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0031914977     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.4.2153     Document Type: Article

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