TNF Receptor-2-Triggered Apoptosis Is Associated with the Down-Regulation of Bcl-xL on Activated T Cells and Can Be Prevented by CD28 Costimulation

Journal of Immunology

Volumn 158, Issue 2, 1997, Pages 598-603

  Lin, Rong Hwa ^a   Hwang, Yuh Wen ^a   Yang, Bei Chang ^b   Lin, Che Sheng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BCL2L1 PROTEIN, MOUSE; CD28 ANTIGEN; MESSENGER RNA; MONOCLONAL ANTIBODY; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN BCL X; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; DOWN REGULATION; DRUG EFFECT; FEMALE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; PROTEIN BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; APOPTOSIS; BCL-X PROTEIN; DOWN-REGULATION; FEMALE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0031567897     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (66)

1. Ashwell, J. D., D. L. Longo, and S. H. Bridges. 1987. T-cell tumor elimination as result of T-cell receptor-mediated activation. Science 237:61.
2. Russell, J. H. 1995. Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7:382.
3. Kabelitz, D., T. Pohl, and K. Pechhold. 1993. Activation-induced cell death (apoptosis) of mature peripheral T lymphocytes. Immunol. Today 14:338.
4. Raff, M. C. 1992. Social controls on cell survival and cell dealt. Nature 356:397.
5. Raff, M. C., B. A. Barres, J. F. Burne, H. S. Coles, Y. Ishizaki, M. D. Jacobson. 1993. Programmed cell death and the control of cell survival: lessons from the nervous system. Science 262:695.
6. Steller, H., and M. E. Grether. 1994. Programmed cell death in Drosophila. Neuron 13:1269.
7. Steller, H. 1995. Mechanisms and genes of cellular suicide. Science 267:1445.
8. Cohen, J. J., R. C. Duke, V. A. Fadok, and K. S. Sellins. 1992. Apoptosis and programmed cell death in immunity. Annu. Rev. Immunol. 10:267.
9. Green, D. R., and D. W. Scott. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476.
10. Russell, J. H., C. L. White, D. Y, Loh, and P. Meleedy-Rey. 1991. Receptor-stimulated death pathway is opened by antigen on mature T cells. Proc. Natl. Acad. Sci. USA 88:2151.
11. Radvanyi, L. G., G. B. Mills, and R. G. Miller. 1993. Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death. J. Immunol. 150:5704.
12. Brunner, T., R. J. Mogil, D. LaFace, N. J. Yoo, A. Mahboubi, F. Echeverri, S. J. Martin, W. R. Force, D. H. Lynch, C. F. Ware, and D. R. Green. 1995. Cell-autonomous Fas/Fas-ligand interaction mediates activation-induced apoptosis in T cell hybridomas. Nature 373:441.
13. Dhein, J., H. Walczak, C. Baumler, K.-M. Debatin, and P. H. Krammer. 1995. Automne T-cell suicide mediated by APO-1/Fas. Nature 373:438.
14. Ju, S.-T., D. J. Panka, H. Cui, R. Ettinger, M. El-Kaharib, D. H. Sherr, B. Z. Stanger, and A. Marshak-Rolhstein. 1995. Fas/FasL interactions required for programmed cell death after T-cell activation. Nature 373:444.
15. Osborne, B. A. 1996. Apoptosis and the maintenance of homeostasis in the immune system. Curr. Opin. Immunol. 8:245.
16. Smith, C. A., T. Farrah, and R. G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 76:959.
17. Lai, N.-S., J.-L. Lan, C.-L. Yu, and R.-H. Lin. 1995. Role of tumor necrosis factor-α in the regulation of activated synovial T cell growth: down-regulation of synovial T cells in rheumatoid arthritis patients. Eur. J. Immunol. 25:3243.
18. Zheng, L., G. Fisher, R. E. Miller, J. Peschon, D. H. Lynch, and M. J. Lenardo. 1995. Induction of apoptosis in mature T cells by tumor necrosis factor. Nature 377:348.
19. Tartaglia, L. A., T. M. Ayres, G. H. W. Wong, and D. V. Goeddel. 1993. A novel domain within the 55-kd TNF receptor signals cell death. Cell 74:845.
20. Enari, M., H. Hug, and S. Nagata, 1995. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78.
21. Los. M., M. V. de Craen, L. C. Penning, H. Schenk, M. Wetendotp, P. A. Baeuerle, W. Groege, P. H. Krammer, W. Fiers, and K. Schulze-Osthoff. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81.
22. Tewari, M., and V. M. Dixit. 1995. Fas- and TNF-induced apoptosis is inhibited by poxvirus crmA gene product. J. Biol. Chem. 270:3255.
23. Hsu, H., J. Ziang, and D. V. Goeddel. 1995. The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation. Cell 81:496.
24. Hsu, H., H.-B. Shu, M.-G. Pan, and D. V. Goeddel. 1996. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptors 1 signal transduction pathways. Cell 84:299.
25. Clement, M.-V., and I. Stamenkovic. 1994. Fas and tumor necrosis factor receptor-mediated cell death: similarities and distinctions. J. Exp. Med. 180:557.
26. Tartaglia, L. A., and D. V. Goeddel. 1991. Two TNF receptors. Immunol. Today 13:151.
27. Vaux, D. L., S. Cory, and J. M. Adams. 1988. Bcl-2 gene promotes hemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335: 440.
28. Boise, L. H., M. Gonzalez-Garcia, C. E. Postema, L. Ding, T. Lindsten, L. A. Turka, X. Mao, G. Nunez, and C. B. Thompson. 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597.
29. L. Immunity 3:87.
30. Nakayama, K.-I., K. Nakayama, I. Negishi, K. Kuida, Y. Shinkai, M. C. Louie, L. E. Fields, P. J. Lucas, V. Stewart, F. W. Alt, and D. Y. Loh. 1993. Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice. Science 261:1584.
31. Strasser, A. 1995. Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms. Curr. Opin. Immunol. 7:228.
32. June, C. H., J. A. Bluestone, L. M, Nadler, and C. B. Thompson. 1994. The B7 and CD28 receptor families. Immunol. Today 15:321.
33. Jenkins, M. K. 1994. The ups and downs of costimulation. Immunity 1:443.
34. Linsley, P. S., and J. A. Ledbetter. 1993. The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11:191.
35. Lindsten, T., C. H. June, J. A. Ledbetter, G. Stella, and C. B. Thompson. 1989. Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway. Science 244:339.
36. Fraser, J. D., B. A. Irving, G. R. Crabtree, and A. Weiss. 1991. Regulation of IL-2 gene enhancer activity by the T cell accessory molecule CD28. Science 251:313.
37. Parijs, L. V., A. Ibraghimov, and A. K. Abbas. 1996. The role of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4:321.
38. Radvanyi, L. G., Y. Shi, H. Vazin, A. Sharma, R. Dhala, G. B. Mills, and R. G. Miller. 1996. CD28 costimulation inhibits TCR-induced apoptosis during a primary T cell response. J. Immunol 156:1788.
39. Memon, S. A., M. B. Moreno, D. Petrak, and C. M. Zacharchuk. 1995. Bcl-2 blocks glucocorticoid-but not Fas-or activation-induced apoptosis in a T cell hybridoma. J. Immunol. 155:4644.
40. Strasser, A., A. W. Harris, D. C. S. Huang, P. H. Krammer, and S. Cory. 1996. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14:6136.
41. Loetscher, H., Y. C. E. Pan, H. W. Lahm, R. Gentz, M. Brockhaus, H. Tabuchi, and W. Lesslauer. 1990. Molecular cloning and expression of the human 55-kd tumor necrosis factor receptor. Cell 61:351.
42. Lewis, M., L. A. Tartaglia, A. Lee, G. L. Bennett, G. C. Rice, G. H. W. Wong, E. Y. Chen, and D. V. Goeddel. 1991. Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrated one receptor is species specific. Prof. Natl. Acad. Sci. USA 88:2830.
43. Brockhaus, M., H. J. Schoenfeld, E. J. Schlaeger, W. Hunziker, W. Lesslauer, and H. Loetscher. 1990. Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies. Proc. Natl. Acad. Sci. USA 87: 3127.
44. Ware, C. F., P. D. Crowe, T. L. Vanarsdale, J. L. Andrews, M. H. Grayson, R. Jerzy, C. A. Smith, and R. G. Goodwin. 1991. Tumor necrosis factor receptor expression in T lymphocytes. J. Immunol. 147:4229.
45. Gilat, D., L. Cahalon, R. Hershkoviz, and O. Leider. 1996. Interplay of T cells and cytokines in the context of enzymatically modified extracellular matrix, Immunol. Today 17:16.
46. + T cells via protein tyrosine. J. Immunol. 153:554.
47. Grell, M., E. Douni, H. Wajant, M. Loehden, M. Clauss, B. Maxeiner, S. Georgopoulos, W. Lesslauer, G. Kollias, K. Pfizenmaier, and P. Scheurich. 1995. The transmembrane form of TNF is the prime activating ligand of the 80-kDa TNF receptor. Cell 83:793.
48. Kinknabwala, M., P. Sehajpal, E. Skolnik, D. Smith, V. K. Sharma, H. Vlassara, A. Cerami, and M. Suthanthiran. 1990. A novel addition to the T cell repertory: cell surface expression of TNF by activated normal human T cells. J. Exp. Med. 171:941.
49. Liu, C. C., P. A. Detmers, S. Jiang, and J. D.-E. Young. 1989. Identification and characterization of a membrane-bound cytotoxin of murine cytolytic lymphocytes that is related to TNF. Proc. Natl. Acad Sci. USA 86:3286.
50. Tartaglia, L. A., R. F. Weber, I. S. Figari, C. Reynolds, M. A. Palladino, Jr., and D. V. Goeddel. 1991. The two different receptors for tumor necrosis factor mediate distinct cellular responses. Proc. Natl. Acad. Sci. USA 88:9292.
51. Yokota, S., T. D. Geppert, and P. E. Lipsky. 1988. Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-α. J. Immunol. 140:531.
52. Vella, A. T., J. E. McCormack, P. E. Linsley, J. W. Kappler, and P. Marrack. 1995. Lipopolysaccharide interferes with the induction of peripheral T cell death. Immunity 2:261.
53. Klas, C., K.-M. Debatin, R. R. Jonker, and P. H. Krammer. 1993. Activation interferes with the APO-1 pathway in mature human T cells. Int. Immunol. 5:625.
54. Miyawaki, T., T. Uehara, R. Nibu, T. Tsuji, A. Yachie, S. Yonehara, and N, Taniguchi. 1992. Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J. Immunol. 149:3753.
55. Boehme, S. A., and M. J. Lenardo. 1993. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23:1552.
56. Nishioka, W. K., and R. M. Welsh. 1994. Susceptibility to cytotoxic T lymphocyte-induced apoptosis is a function of the proliferative status of the target. J. Exp. Med. 179:769.
57. Ramsdell, F., M. S. Seaman, R. E. Miller, K. S. Picha, M. K. Kennedy, and D. H. Lynch. 1994. Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. Int. Immunol. 6:1545.
58. + T cells is regulated by antigen-presenting cell. J. Immunol. 150: 3832.
59. Allison, J. P. 1994. CD28-B7 interactions in T-cell activation. Curr. Opin. Immunol. 6:414.
60. Thompson, C. B., T. Lindsten, J. Ledbetter, S. L. Kunkel, H. A. Young, S. G. Emerson, J. M. Leiden, and C. H. June. 1989. CD28 activation pathway regulates the production of multiple T cell-derived lymphokines/cytokines. Proc. Natl. Acad. Sci. USA 86:1333.
61. Lenardo, M. J. 1991. Interleukin-2 programs mouse T lymphocytes for apoptosis. Nature 353:858.
62. Boldin, M. P., E. E. Varfolomeev, Z. Pancer, I. L. Mett, J. H. Camonis, and D. Wallach. 1995. A novel protein that interacts with death domain of Fas/APO-1 contains a sequence motif related to the death domain. J. Biol. Chem. 270:7795.
63. Chinnaiyan, A. M., K. O'Rourke, M. Tewari, and V. M. Dixit. 1995. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 81:505.
64. Stanger, B. Z., P. Leder, T.-H. Lee, E. Kim, and B. Seed. 1995. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81:513.
65. Rothe, M., S. C. Wong, W. J. Henzel, and D. V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75-kDa tumor necrosis factor receptor. Cell 78:681.
66. Rothe, M., M.-G. Pan, W. J. Henzel, T. M. Ayres, and D. V. Goeddel. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83:1243.