Regulation of matrix metalloproteinases and plasminogen activator inhibitor-1 synthesis by plasminogen in cultured human vascular smooth muscle cells

Circulation Research

Volumn 78, Issue 1, 1996, Pages 44-49

  Lee, Elaine ^a   Vaughan, Douglas E ^b   Parikh, Smruti H ^c   Grodzinsky, Alan J ^a   Libby, Peter ^c   Lark, Michael W ^d   Lee, Richard T ^a,c,e  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

collagenase; plasmin; plasminogen; stromelysin; vascular smooth muscle

Indexed keywords

COLLAGENASE; PLASMIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERINE PROTEINASE; STROMELYSIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DEGRADATION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 0030042886     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.1.44     Document Type: Article

References (33)

1. Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med. 1994;330:1431-1438.
2. Ross R, Klebanoff SJ. The smooth muscle cell, I: in vivo synthesis of connective tissue proteins. J Cell Biol. 1971;50:159-171.
3. Wight TN, Ross R. Proteoglycans in primate arteries, I: ultrastructural localization and distribution in the intima. J Cell Biol. 1975;67:660-674.
4. Kishi J-I, Hayakawa T. Synthesis of latent collagenase and collagenase inhibitor by bovine aortic medial explants and cultured medial smooth muscle cells. Connect Tissue Res. 1989;19:63-76.
5. Henney AM, Wakeley PR, Davies MJ, Foster K, Hembry R, Murphy G, Humphries S. Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization. Proc Natl Acad Sci U S A. 1991;88:8154-8158.
6. Welgus HG, Campbell EJ, Cury JD, Eisen AZ, Senior RM, Wilhelm SM, Goldberg GI. Neutral metalloproteinases produced by human mononuclear phagocytes: enzyme profile, regulation, and expression during cellular development. J Clin Invest. 1990;86: 1496-1502.
7. Werb Z, Mainardi CL, Vater CA, Harris EDJ. Endogenous activation of latent collagenase by rheumatoid synovial cells: evidence for a role of plasminogen activator. N Engl J Med. 1977;296: 1017-1023.
8. He C, Wilhelm SM, Pentland AP, Marmer BL, Grant GA, Eisen AZ, Goldberg GI. Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A. 1989;86:2632-2636.
9. Sperti G, Quax P, Van Leeuwen R, Kluft C. PAI-1 and t-PA mRNAs are expressed by vascular smooth muscle cells in vivo. Circulation. 1990;82(suppl III):III-573. Abstract.
10. Knudsen BS, Harpel PC, Nachman RL. Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells. J Clin Invest. 1987;80:1082-1089.
11. Werb Z, Aggeler J. Proteases induce secretion of collagenase and plasminogen activator by fibroblasts. Proc Natl Acad Sci U S A. 1978;75:1839-1843.
12. Amento EP, Ehsani N, Palmer H, Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb. 1991;11:1223-1230.
13. Edwards IJ, Wagner WD, Owens RT. Macrophage secretory products selectively stimulate dermatan sulfate proteoglycan production in cultured arterial smooth muscle cells. Am J Pathol. 1990;136: 609-621.
14. Schönherr E, Järveläinen HT, Sandell LJ, Wight TN. Effects of platelet-derived growth factor and transforming growth factor-β1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells. J Biol Chem. 1991;266: 17640-17647.
15. Chen J-K, Hoshi H, McKeehan WL. Transforming growth factor type α specifically simulates synthesis of proteoglycan in human adult arterial smooth muscle cells. Proc Natl Acad Sci U S A. 1987; 84:5287-5291.
16. Schlumberger W, Thie M, Rauterberg J, Robenek H. Collagen synthesis in cultured aortic smooth muscle cells: modulation by collagen lattice culture, transforming growth factor-β1 and epidermal growth factor. Arterioscler Thromb. 1991;11:1660-1666.
17. Galis ZS Muszynski M, Sukhova GK, Simon-Monssey E, Unemori EN, Lark MW, Amento E, Libby P. Cytokine-stimulated vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion. Circ Res. 1994;75:181-189.
18. Walakovits LA, Moore VL, Bhardwaj N, Gallick GS Lark MW. Detection of stromelysin and collagenase in synovial fluid from patients with rheumatoid arthritis and posttraumatic knee injury. Arthritis Rheum. 1992;35:35-42.
19. Gimbrone MA, Cotran RS. Human vascular smooth muscle in culture. Lab Invest. 1975;33:16-27.
20. Saarialho-Kere UK, Welgus HG, Parks WC. Distinct mechanisms regulate interstitial collagenase and 92-kDa gelatinase expression in human monocytic-like cells exposed to bacterial endotoxin. J Biol Chem. 1993;268:17354-17361.
21. Sawdey MS, Loskutoff DJ. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo: tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-α, and transforming growth factor-β. J Clin Invest. 1991;88:1346-1353.
22. Sawdev M, Podor TJ, Loskutoff DJ. Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells: induction by transforming growth factor-β, lipopolysaccharide, and tumor necrosis factor-α. J Biol Chem. 1989;264: 10396-10401.
23. Levin J, Bang FB. Clottable protein in Limulus: its localization and kinetics of its coagulation by endotoxin. Thromb Diath Haemorrh. 1968;19:186-197.
24. Ridker PM, Vaughan DE, Stampfer MJ, Manson JE, Shen C, Newcomer LM, Goldhaber SZ, Hennekens CH. Baseline fibrinolytic state and the risk of future venous thrombosis. Circulation. 1992;85:1822-1827.
25. Noda-Heiny H, Daugherty A, Sobel BE. Augmented urokinase receptor expression in atheroma. Arterioscler Thromb Vasc Biol. 1995;15:37-43.
26. Grobmyer SR, Kuo A, Orishimo M, Okada SS, Cines DB, Barnathan ES. Determinants of binding and internalization of tissue-type plasminogen activator by human vascular smooth muscle and endothelial cells. J Biol Chem. 1993;268:13291-13300.
27. Etingin OR, Hajjar DP, Hajjar KA, Harpel PC, Nachman RL. Lipoprotein (a) regulates plasminogen activator inhibitor-1 expression in endothelial cells: a potential mechanism in thrombogenesis. J Biol Chem. 1991;266:2459-2465.
28. Laug WE, Aebersold R, Jong A, Rideout W, Bergman BL, Baker J. Isolation of multiple types of plasminogen activator inhibitors from vascular smooth muscle cells. Thromb Haemost. 1989;61: 517-521.
29. Sottrup-Jensen, Claeys H, Zajdel M, Petersen TE, Magnusson S. The primary structure of human plasminogen: isolation of two lysine-binding fragments and one 'mini-' plasminogen (MW, 38,000) by elastase-catalyzed-specific limited proteolysis. In: Davidson JF, Rowan RM, Samama MM, Desnoyers PC, eds. Progress in Chemical Fibrinolysis and Thrombolysis. New York, NY: Raven Press Publishers; 1978;3:191-209.
30. Wu H-L, Wu I-S, Fang R-Y, Hau J-S, Wu D-H, Chang B-I, Lin T-M, Shi G-Y. The binding of plasminogen fragments to cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1992;188:703-711.
31. Mignatti P, Rifkin DB. Biology and biochemistry of proteinases in tumor invasion. Physiol Rev. 1993;73:161-195
32. Werb Z, Hembry RM, Murphy G, Aggeler J. Commitment to expression of the metalloendopeptidases, collagenase and stromelysin: relationship of inducing events to changes in cytoskeletal architecture. J Cell Biol. 1986;102:697-702.
33. Werb Z, Tremble PM, Behrendtsen O, Crowley E, Damsky CH. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J Cell Biol. 1989;109: 877-889.