Structural changes of tumor necrosis factor α associated with membrane insertion and channel formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 3, 1996, Pages 1021-1026

  Baldwin, Rae Lynn ^a,c   Stolowitz, Mark L ^b   Hood, Leroy ^b   Wisnieski, Bernadine J ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c CEDARS SINAI MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

conformation; cytokine; molten globule; pH dependency; photolabeling

Indexed keywords

AMINO ACID; DIMYRISTOYLPHOSPHATIDYLCHOLINE; PROTEINASE; SERINE CARBOXYPEPTIDASE; TUMOR NECROSIS FACTOR ALPHA;

ACIDIFICATION; ARTICLE; BILAYER MEMBRANE; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; FLUOROMETRY; HYDROPHOBICITY; MEMBRANE BINDING; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTON TRANSPORT;

AMINO ACID SEQUENCE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; ENDOPEPTIDASES; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROMETRY, FLUORESCENCE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030034370     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.3.1021     Document Type: Article

References (39)

1. Beutler, B. & Cerami, A. (1989) Annu. Rev. Immunol. 7, 626-655.
2. Vassalli, P. (1992) Annu. Rev. Immunol. 10, 411-452.
3. Tracy, K. J. & Cerami, A. (1993) Annu. Rev. Cell Biol. 9, 317-343.
4. Loetscher, H., Pan, E. Y.-C., Lahm, H. W., Gentz, R., Brockhaus, M., Tabuchi, H. & Lesslauer, L. (1990) Cell 61, 351-359.
5. Schall, T. J., Lewis, M., Koller, K. J., Lee, A., Rice, G. C., Wong, G. H., Gatanaga, T., Granger, G. A., Lentz, R., Raab, H., Kohr, W. J. & Goeddel, D. V. (1990) Cell 61, 361-370.
6. Smith, C. A., Davis, T., Anderson, D., Solam, L., Beckmann, M. P., Jerzy, R., Dower, S. K., Cosman, D. & Goodwin, R. G. (1990) Science 248, 1019-1023.
7. Kull, F. C., Jr., Jacobs, S. & Cuatrecasas, P. (1985) Proc. Natl. Acad. Sci. USA 82, 5756-5760.
8. Nii, A., Fan, D. & Fidler, I. J. (1991) J. Immunother. 10, 13-19.
9. Muchmore, A., Decker, J., Shaw, A. & Wingfield, P. (1990) Cancer Res. 50, 6285-6290.
10. Lucas, R., Magez, S., De Leys, R., Fransen, L., Scheerlinck, J.-P., Rampelberg, M., Sablon, E. & De Baetselier, P. (1994) Science 263, 814-817.
11. Smith, M. R., Munger, W. E., Kung, H.-F., Takacs, L. & Durum, S. K. (1990) J. Immunol. 144, 162-169.
12. Morishige, H., Ohkuma, T. & Kaji, A. (1993) Biochim. Biophys. Acta 1151, 59-68.
13. Tsujimoto, M., Yip, Y. K. & Vilcek, J. (1985) Proc. Natl. Acad. Sci. USA 82, 7626-7630.
14. Kull, F. C., Jr., & Besterman, J. M. (1990) J. Cell. Biochem. 42, 1-12.
15. Kull, F. C., Jr. & Cuatrecasas, P. (1981) Cancer Res. 41, 4885-4890.
16. Niitsu, Y., Watanabe, N., Sone, H., Neda, H., Yamauchi, N. & Urushizaki, I. (1985) Jpn. J. Cancer Res. 76, 1193-1197.
17. Liddil, J. D., Dorr, R. T. & Scuderi, P. (1989) Cancer Res. 49, 2722-2728.
18. Baldwin, R. L., Chang, M. P., Bramhall, J., Graves, S., Bonavida, B. & Wisnieski, B. J. (1988) J. Immunol. 141, 2352-2357.
19. Chang, M. P. & Wisnieski, B. J. (1990) Infect. Immun. 58, 2644-2650.
20. Silver, I. A., Murrills, R. J. & Etherington, D. J. (1988) Exp. Cell Res. 175, 266-276.
21. Mellman, I., Fuchs, R. & Helenius, A. (1986) Annu. Rev. Biochem. 55, 663-700.
22. Jones, E. Y., Stuart, D. I. & Walker, N. P. C. (1989) Nature (London) 338, 225-228.
23. Eck, M. J. & Sprang, S. R. (1989) J. Biol. Chem. 264, 17595-17605.
24. Kagan, B. L., Baldwin, R. L., Munoz, D. & Wisnieski, B. J. (1992) Science 255, 1427-1430.
25. Ernst, W. A., Mirzabekov, T., Kagan, B. L. & Wisnieski, B. J. (1994) Biophys. J. 66, A204 (abstr.).
26. Kagan, B. L., Mirzabekov, T., Munoz, D., Baldwin, R. L. & Wisnieski, B. J. (1993) Ann. N.Y. Acad. Sci. 707, 317-327.
27. Baldwin, R. L., Mirzabekov, T., Kagan, B. L. & Wisnieski, B. J. (1995) J. Immunol. 156, 790-798.
28. Bychkova, V. E., Pain, R. H. & Ptitsyn, O. B. (1988) FEBS Lett. 238, 231-234.
29. Zalman, L. S. & Wisnieski, B. J. (1985) Infect. Immun. 50, 630-635.
30. Chamberlain, J. P. (1979) Anal. Biochem. 98, 132-135.
31. Matsudaira, P. (1987) J. Biol. Chem. 262, 10035-10038.
32. Farahbakhsh, Z. T., Baldwin, R. L. & Wisnieski, B. J. (1987) J. Biol. Chem. 262, 2256-2261.
33. Wisnieski, B. J. & Bramhall, J. S. (1981) Nature (London) 289, 319-321.
34. Sprang, S. R. & Eck, M. J. (1992) in Tumor Necrosis Factors: The Molecules and Their Emerging Role In Medicine, ed. Beutler, B. (Raven, New York), pp. 11-32.
35. Sprang, S. R. & Eck, M. J. (1990) in Current Research in Protein Chemistry: Techniques, Structure, and Function, ed. Villafranca, J. J. (Academic, New York), pp. 383-394.
36. Banner, D. W., D'Arcy, A., Janes, W., Gentz, R., Schoenfeld, H.-J., Broger, C., Loetscher, H. & Lesslauer, W. (1993) Cell 73, 431-445.
37. Hu, V. W., Esser, A. F., Podack, E. R. & Wisnieski, B. J. (1981) J. Immunol. 27, 380-386.
38. Ishida, B., Cawley, D. B., Reue, K. & Wisnieski, B. J. (1983) J. Biol. Chem. 258, 5933-5937.
39. Zalman, L. S. & Wisnieski, B. J. (1984) Proc. Natl. Acad. Sci. USA 81, 3341-3345.