메뉴 건너뛰기




Volumn 8, Issue 5, 1997, Pages 341-348

Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; HYDRAZONE DERIVATIVE; NEUROPROTECTIVE AGENT; SEMAPIMOD; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031262936     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199711000-00005     Document Type: Article
Times cited : (159)

References (55)
  • 1
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
    • Anonymous: Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 333:1581-1587, 1995.
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 2
    • 0028292231 scopus 로고
    • Tumor necrosis factor-α expression in ischemic neurons
    • Liu T, Clark RK, McDonnell PC, et al: Tumor necrosis factor-α expression in ischemic neurons. Stroke 25:1481-1488, 1994.
    • (1994) Stroke , vol.25 , pp. 1481-1488
    • Liu, T.1    Clark, R.K.2    McDonnell, P.C.3
  • 3
    • 0030601808 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-alpha reduces focal cerebral ischemic injury in the spontaneously hypertensive rat
    • Dawson DA, Martin D, Hallenbeck JM: Inhibition of tumor necrosis factor-alpha reduces focal cerebral ischemic injury in the spontaneously hypertensive rat. Neurosci Lett 218:41-44, 1996.
    • (1996) Neurosci Lett , vol.218 , pp. 41-44
    • Dawson, D.A.1    Martin, D.2    Hallenbeck, J.M.3
  • 4
    • 0031051349 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor and amelioration of brain infarction in mice
    • Nawashiro H, Martin D, Hallenbeck JM: Inhibition of tumor necrosis factor and amelioration of brain infarction in mice. J Cereb Blood Flow Metab 17:229-232, 1997.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 229-232
    • Nawashiro, H.1    Martin, D.2    Hallenbeck, J.M.3
  • 5
    • 0029926093 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor alpha activity in rat brain is associated with cerebroprotection after closed head injury
    • Shohami E, Bass R, Wallach D, Yamin A, Gallily R: Inhibition of tumor necrosis factor alpha activity in rat brain is associated with cerebroprotection after closed head injury. J Cereb Blood Flow Metab 16:378-384, 1996.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 378-384
    • Shohami, E.1    Bass, R.2    Wallach, D.3    Yamin, A.4    Gallily, R.5
  • 6
    • 0029899586 scopus 로고    scopus 로고
    • Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
    • Bruce AJ, Boling W, Kindy M, et al: Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors. Nat Med 2:788-789, 1996.
    • (1996) Nat Med , vol.2 , pp. 788-789
    • Bruce, A.J.1    Boling, W.2    Kindy, M.3
  • 7
    • 0024365383 scopus 로고
    • Anticachectin/tumor necrosis factor-alpha antibodies attenuate development of cachexia in tumor models
    • Sherry BA, Gellin J, Fong Y, et al: Anticachectin/tumor necrosis factor-alpha antibodies attenuate development of cachexia in tumor models. FASEB J 3:1956-1962, 1989.
    • (1989) FASEB J , vol.3 , pp. 1956-1962
    • Sherry, B.A.1    Gellin, J.2    Fong, Y.3
  • 8
    • 0023028369 scopus 로고
    • Shock and tissue injury induced by recombinant human cachectin
    • Tracey KJ, Beutler B, Lowry SF, et al: Shock and tissue injury induced by recombinant human cachectin. Science 234:470-474, 1986.
    • (1986) Science , vol.234 , pp. 470-474
    • Tracey, K.J.1    Beutler, B.2    Lowry, S.F.3
  • 10
    • 0029066877 scopus 로고
    • Neurotoxicity of advanced glycation endproducts (AGEs) during focal stroke, and neuroprotective effects of aminoguanidine
    • Zimmerman GA, Meistrell M III, Bloom O, et al: Neurotoxicity of advanced glycation endproducts (AGEs) during focal stroke, and neuroprotective effects of aminoguanidine. Proc Natl Acad Sci USA 92:3744-3748, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3744-3748
    • Zimmerman, G.A.1    Meistrell III, M.2    Bloom, O.3
  • 11
    • 0029794989 scopus 로고    scopus 로고
    • Cerebroprotective effects of aminoguanidine in a rodent model of stroke
    • Cockroft KM, Meistrell M III, et al: Cerebroprotective effects of aminoguanidine in a rodent model of stroke. Stroke 27:1393-1398, 1996.
    • (1996) Stroke , vol.27 , pp. 1393-1398
    • Cockroft, K.M.1    Meistrell III, M.2
  • 12
    • 0027937489 scopus 로고
    • Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia
    • Sharkey J, Butcher SP: Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Nature 371:336-339, 1994.
    • (1994) Nature , vol.371 , pp. 336-339
    • Sharkey, J.1    Butcher, S.P.2
  • 13
    • 0023786051 scopus 로고
    • Focal brain ischemia in the rat: Methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries
    • Brint S, Jacewicz M, Kiessling M, Tanabe J, Pulsinelli W: Focal brain ischemia in the rat: Methods for reproducible neocortical infarction using tandem occlusion of the distal middle cerebral and ipsilateral common carotid arteries. J Cereb Blood Flow Metab 8:474-485, 1988.
    • (1988) J Cereb Blood Flow Metab , vol.8 , pp. 474-485
    • Brint, S.1    Jacewicz, M.2    Kiessling, M.3    Tanabe, J.4    Pulsinelli, W.5
  • 14
    • 0029258451 scopus 로고
    • An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammatory and endotoxin lethality
    • Bianchi M, Ulrich P, Bloom O, et al: An inhibitor of macrophage arginine transport and nitric oxide production (CNI-1493) prevents acute inflammatory and endotoxin lethality. Mol Med 1:254-266, 1995.
    • (1995) Mol Med , vol.1 , pp. 254-266
    • Bianchi, M.1    Ulrich, P.2    Bloom, O.3
  • 15
    • 15844399881 scopus 로고    scopus 로고
    • Suppression of Proinflammatory Cytokines in Monocytes by a Tetravalent Guanylhydrazone
    • Bianchi M, Bloom O, Raabe T, et al: Suppression of Proinflammatory Cytokines in Monocytes by a Tetravalent Guanylhydrazone. J Exp Med 83:927-936, 1996.
    • (1996) J Exp Med , vol.83 , pp. 927-936
    • Bianchi, M.1    Bloom, O.2    Raabe, T.3
  • 16
    • 0029991493 scopus 로고    scopus 로고
    • CNI-1493 inhibits monocyte/ macrophage tumor necrosis factor by suppression of translation efficiency
    • Cohen, PS, Nakshaatri H, Dennis J, et al: CNI-1493 inhibits monocyte/ macrophage tumor necrosis factor by suppression of translation efficiency. Proc Natl Acad Sci USA 93:3967-3971, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3967-3971
    • Cohen, P.S.1    Nakshaatri, H.2    Dennis, J.3
  • 17
    • 0030803470 scopus 로고    scopus 로고
    • The critical role of p38 MAP kinase in T cell HIV-1 replication
    • Cohen PS, Schmidtmayerova H, Dennis J, et al: The critical role of p38 MAP kinase in T cell HIV-1 replication. Mol Med 3:339-346, 1997.
    • (1997) Mol Med , vol.3 , pp. 339-346
    • Cohen, P.S.1    Schmidtmayerova, H.2    Dennis, J.3
  • 18
    • 6444223541 scopus 로고
    • High-performance liquid chromatographic method for guanylhydrazone compounds which prevent acute inflammation and toxic shock syndrome
    • Cerami C, Xhang X, Ulrich P, Bianchi M, Tracey KJ, Berger BJ: High-performance liquid chromatographic method for guanylhydrazone compounds which prevent acute inflammation and toxic shock syndrome. J Chromatog 675:71-75, 1995.
    • (1995) J Chromatog , vol.675 , pp. 71-75
    • Cerami, C.1    Xhang, X.2    Ulrich, P.3    Bianchi, M.4    Tracey, K.J.5    Berger, B.J.6
  • 19
    • 0000562533 scopus 로고    scopus 로고
    • A low molecular weight macrophage inhibitor decreases severity of pancreatitis through inhibition of IL-1 and TNF production
    • Fink G, Yang J, Carter G, et al: A low molecular weight macrophage inhibitor decreases severity of pancreatitis through inhibition of IL-1 and TNF production. Surg Forum 47:137-139, 1997.
    • (1997) Surg Forum , vol.47 , pp. 137-139
    • Fink, G.1    Yang, J.2    Carter, G.3
  • 20
    • 0013502215 scopus 로고    scopus 로고
    • Suppression of acute experimental autoimmune encephalitis by CNI-1493, an inhibitor of TNF synthesis
    • abstract
    • Martiney J, Rajan A, Cerami A, Tracey KJ, Brosnan CF: Suppression of acute experimental autoimmune encephalitis by CNI-1493, an inhibitor of TNF synthesis. J Invest Med 44:200, 1996 (abstract).
    • (1996) J Invest Med , vol.44 , pp. 200
    • Martiney, J.1    Rajan, A.2    Cerami, A.3    Tracey, K.J.4    Brosnan, C.F.5
  • 21
    • 0030831395 scopus 로고    scopus 로고
    • Small molecule inhibition of TNF gene processing during acute pancreatitis prevents cytokine cascade progression and attenuates pancreatitis severity
    • In press
    • Denham W, Fink G, Yang J, Ulrich P, Tracey JJ, Norman J: Small molecule inhibition of TNF gene processing during acute pancreatitis prevents cytokine cascade progression and attenuates pancreatitis severity. Am Surgeon 1997. In press.
    • (1997) Am Surgeon
    • Denham, W.1    Fink, G.2    Yang, J.3    Ulrich, P.4    Tracey, J.J.5    Norman, J.6
  • 22
    • 6444230199 scopus 로고    scopus 로고
    • A low molecular weight TNF inhibitor (CNI-1493) protects mice from sepsis and sepsis-associated pulmonary infiltration
    • abstract
    • Villa P, Meazza C, Sironi M, et al: A low molecular weight TNF inhibitor (CNI-1493) protects mice from sepsis and sepsis-associated pulmonary infiltration. Eur Cytokine Network 7:506, 1997 (abstract).
    • (1997) Eur Cytokine Network , vol.7 , pp. 506
    • Villa, P.1    Meazza, C.2    Sironi, M.3
  • 23
    • 0000935929 scopus 로고    scopus 로고
    • A novel inhibitor of inflammatory cytokine production (CNI-1493) is cerebroprotective in permanent focal cerebral ischemia
    • abstract
    • Cockroft KM, Meistrell M III, Ulrich P, Cerami A, Tracey KJ: A novel inhibitor of inflammatory cytokine production (CNI-1493) is cerebroprotective in permanent focal cerebral ischemia. Surg Forum 47:568-570, 1999 (abstract).
    • (1999) Surg Forum , vol.47 , pp. 568-570
    • Cockroft, K.M.1    Meistrell III, M.2    Ulrich, P.3    Cerami, A.4    Tracey, K.J.5
  • 24
    • 0025358131 scopus 로고
    • Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat
    • Colletti LM, Remick DG, Burtch GD, Kunkel SL, Stricter RM, Campbell DA Jr: Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest 85:1936-1943, 1990.
    • (1990) J Clin Invest , vol.85 , pp. 1936-1943
    • Colletti, L.M.1    Remick, D.G.2    Burtch, G.D.3    Kunkel, S.L.4    Stricter, R.M.5    Campbell Jr., D.A.6
  • 25
    • 0023189866 scopus 로고
    • Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria
    • Grau GE, Fajardo LF, Piguet PF, Allet B, Lambert PH, Vassalli P: Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 237:1210-1212, 1987.
    • (1987) Science , vol.237 , pp. 1210-1212
    • Grau, G.E.1    Fajardo, L.F.2    Piguet, P.F.3    Allet, B.4    Lambert, P.H.5    Vassalli, P.6
  • 26
    • 0025979237 scopus 로고
    • Lipopolysaccharide-induced production of tumor necrosis factor activity in rats with and without risk factors for stroke
    • Hallenbeck JM, Dutka AJ, Vogel SN, Heldman E, Doron DA, Feuerstein G: Lipopolysaccharide-induced production of tumor necrosis factor activity in rats with and without risk factors for stroke. Brain Res 541:115-120, 1991.
    • (1991) Brain Res , vol.541 , pp. 115-120
    • Hallenbeck, J.M.1    Dutka, A.J.2    Vogel, S.N.3    Heldman, E.4    Doron, D.A.5    Feuerstein, G.6
  • 27
    • 6444229476 scopus 로고    scopus 로고
    • Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493
    • abstract
    • Tracey KJ: Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493. J Endotoxin Res 3:12, 1997 (abstract).
    • (1997) J Endotoxin Res , vol.3 , pp. 12
    • Tracey, K.J.1
  • 28
    • 0024202127 scopus 로고
    • Induction of manganous superoxide dismutase by tumor necrosis factor: Possible protective mechanism
    • Wong GHW, Goeddel DV: Induction of manganous superoxide dismutase by tumor necrosis factor: Possible protective mechanism. Science 242: 941-944, 1988.
    • (1988) Science , vol.242 , pp. 941-944
    • Wong, G.H.W.1    Goeddel, D.V.2
  • 29
    • 0029955192 scopus 로고    scopus 로고
    • Brain TNF: Damage limitation or damaged reputation?
    • Rothwell NJ, Luheshi GN: Brain TNF: Damage limitation or damaged reputation? Nat Med 2:746-747, 1996.
    • (1996) Nat Med , vol.2 , pp. 746-747
    • Rothwell, N.J.1    Luheshi, G.N.2
  • 30
    • 0024513152 scopus 로고
    • Cachectin/TNF (tumour necrosis factor)
    • Tracey KJ, Vlassara H, Cerami A: Cachectin/TNF (tumour necrosis factor). Lancet 1:1122-1126, 1989.
    • (1989) Lancet , vol.1 , pp. 1122-1126
    • Tracey, K.J.1    Vlassara, H.2    Cerami, A.3
  • 31
    • 0025639022 scopus 로고
    • Metabolic effects of cachectin/ tumor necrosis factor are modified by site of production: Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominately acute anorexia
    • Tracey KJ, Morgello S, Koplin B, et al: Metabolic effects of cachectin/ tumor necrosis factor are modified by site of production: Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominately acute anorexia. J Clin Invest 86:2014-2024, 1990.
    • (1990) J Clin Invest , vol.86 , pp. 2014-2024
    • Tracey, K.J.1    Morgello, S.2    Koplin, B.3
  • 32
    • 0028934328 scopus 로고
    • Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood How in the rabbit: Role of nitric oxide
    • Tureen J: Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood How in the rabbit: role of nitric oxide. J Clin Invest 95:1086-1091, 1995.
    • (1995) J Clin Invest , vol.95 , pp. 1086-1091
    • Tureen, J.1
  • 33
    • 0022492412 scopus 로고
    • Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential
    • Tracey KJ, Lowry SF, Beutler B, Cerami A, Albert JD, Shires GT: Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential. J Exp Med 164:1368-1373, 1986.
    • (1986) J Exp Med , vol.164 , pp. 1368-1373
    • Tracey, K.J.1    Lowry, S.F.2    Beutler, B.3    Cerami, A.4    Albert, J.D.5    Shires, G.T.6
  • 34
    • 0026555556 scopus 로고
    • Formation of ionpermeable channels by tumor necrosis factor-alpha
    • Kagan BL, Baldwin RL, Munoz D, Wisnieski BJ: Formation of ionpermeable channels by tumor necrosis factor-alpha. Science 255:1427-1430, 1992.
    • (1992) Science , vol.255 , pp. 1427-1430
    • Kagan, B.L.1    Baldwin, R.L.2    Munoz, D.3    Wisnieski, B.J.4
  • 35
    • 0001937054 scopus 로고    scopus 로고
    • Tumor necrosis factor
    • Remick DG, Friedland JS (eds): New York: Marcel Dekker, Inc.
    • Tracey KJ: Tumor necrosis factor. In Remick DG, Friedland JS (eds): Cytokines in Health and Disease. New York: Marcel Dekker, Inc., 1997, pp 223-240.
    • (1997) Cytokines in Health and Disease , pp. 223-240
    • Tracey, K.J.1
  • 36
    • 0023927131 scopus 로고
    • TNF as an activator of vascular endothelium
    • Pober JS: TNF as an activator of vascular endothelium. Ann Instit Pasteur 139:317-323, 1988.
    • (1988) Ann Instit Pasteur , vol.139 , pp. 317-323
    • Pober, J.S.1
  • 37
    • 0024309730 scopus 로고
    • Tumor necrosis factor/cachectin increases permeability of endothelial cell mono-layers by a mechanism involving regulatory G proteins
    • Brett J, Gerlach H, Nawroth P, Steinberg S, Godman G, Stem D: Tumor necrosis factor/cachectin increases permeability of endothelial cell mono-layers by a mechanism involving regulatory G proteins. J Exp Med 169:1977-1991, 1989.
    • (1989) J Exp Med , vol.169 , pp. 1977-1991
    • Brett, J.1    Gerlach, H.2    Nawroth, P.3    Steinberg, S.4    Godman, G.5    Stem, D.6
  • 38
    • 0029164968 scopus 로고
    • Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor
    • Decoster E, Vanhaesebroeck B, Vandenabeele P, Grooten J, Fiers W: Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor. J Biol Chem 270:18473-18478, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 18473-18478
    • Decoster, E.1    Vanhaesebroeck, B.2    Vandenabeele, P.3    Grooten, J.4    Fiers, W.5
  • 39
    • 0029010135 scopus 로고
    • Effect of tumor necrosis factor a and β on human oligodendrocytes and neurons in culture
    • McLaurin J, D'Souza S, Stewart J, et al: Effect of tumor necrosis factor a and β on human oligodendrocytes and neurons in culture. Int J Dev Neurosci 13:369-381, 1995.
    • (1995) Int J Dev Neurosci , vol.13 , pp. 369-381
    • McLaurin, J.1    D'Souza, S.2    Stewart, J.3
  • 40
    • 0028204376 scopus 로고
    • FAS antigen and p55 TNF receptor signal apoptosis through distinct pathways
    • Wong G, Goeddel D: FAS antigen and p55 TNF receptor signal apoptosis through distinct pathways. J Immunol 152:1751-1755, 1994.
    • (1994) J Immunol , vol.152 , pp. 1751-1755
    • Wong, G.1    Goeddel, D.2
  • 41
    • 0029035926 scopus 로고
    • Cytokines in neurodegeneration and repair
    • Rothwell NJ, Strijbos PJ: Cytokines in neurodegeneration and repair. Int J Dev Neurosci 13:179-185, 1995.
    • (1995) Int J Dev Neurosci , vol.13 , pp. 179-185
    • Rothwell, N.J.1    Strijbos, P.J.2
  • 42
    • 0024822793 scopus 로고
    • Antibodies to cachectin/TNF reduce interleukin-1-beta and interleukin-6 appearance during lethal bacteremia
    • Fong Y, Tracey KJ, Moldawer LL, et al: Antibodies to cachectin/TNF reduce interleukin-1-beta and interleukin-6 appearance during lethal bacteremia. J Exp Med 170:1627-1633, 1989.
    • (1989) J Exp Med , vol.170 , pp. 1627-1633
    • Fong, Y.1    Tracey, K.J.2    Moldawer, L.L.3
  • 43
    • 0002461840 scopus 로고
    • The acute and chronic pathophysiological effects of TNF: Mediation of septic shock and wasting (cachexia)
    • Beutler B (ed): New York: Raven Press
    • Tracey KJ: The acute and chronic pathophysiological effects of TNF: Mediation of septic shock and wasting (cachexia). In Beutler B (ed): Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. New York: Raven Press, 1992, pp 255-273.
    • (1992) Tumor Necrosis Factors: the Molecules and Their Emerging Role in Medicine , pp. 255-273
    • Tracey, K.J.1
  • 44
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C: Nitric oxide as a secretory product of mammalian cells. FASEB J 6:3051-3064, 1992.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 45
    • 23444434659 scopus 로고
    • Role of NO production in NMDR receptor-mediated neurotransmitter release in cerebral cortex
    • Montague PR, Gancayco CD, Winn MJ, Marchase RB, Friedlander JJ: Role of NO production in NMDR receptor-mediated neurotransmitter release in cerebral cortex. Science 263:973-976, 1994.
    • (1994) Science , vol.263 , pp. 973-976
    • Montague, P.R.1    Gancayco, C.D.2    Winn, M.J.3    Marchase, R.B.4    Friedlander, J.J.5
  • 46
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson V, Dawson T, Snyder S: Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263:687-690, 1994.
    • (1994) Science , vol.263 , pp. 687-690
    • Zhang, J.1    Dawson, V.2    Dawson, T.3    Snyder, S.4
  • 48
    • 0026656192 scopus 로고
    • Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
    • Relton JK, Rothwell NJ: Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat. Brain Res Bull 29:243-246, 1992.
    • (1992) Brain Res Bull , vol.29 , pp. 243-246
    • Relton, J.K.1    Rothwell, N.J.2
  • 49
    • 0027660930 scopus 로고
    • Involvement of interleukin-1 and lipocortin-1 in ischeamic brain damage
    • Rothwell NJ, Relton JK: Involvement of interleukin-1 and lipocortin-1 in ischeamic brain damage. Cerebrovasc Brain Metab Rev 5:178-198, 1993.
    • (1993) Cerebrovasc Brain Metab Rev , vol.5 , pp. 178-198
    • Rothwell, N.J.1    Relton, J.K.2
  • 50
    • 0027179773 scopus 로고
    • Neuroprotective effects of glutamate antagonists and extracellular acidity
    • Kaku DA, Giffard RG, Choi DW: Neuroprotective effects of glutamate antagonists and extracellular acidity. Science 260:1516-1518, 1993.
    • (1993) Science , vol.260 , pp. 1516-1518
    • Kaku, D.A.1    Giffard, R.G.2    Choi, D.W.3
  • 51
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW: Excitotoxic cell death. J Neurobiol 23:1261-1276, 1992.
    • (1992) J Neurobiol , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 52
    • 0025844833 scopus 로고
    • Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNFα and life in the rat brain
    • Minami M, Kuraishi Y, Satoh M: Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNFα and life in the rat brain. Biochem Biophys Res Commun 176:593-598, 1991.
    • (1991) Biochem Biophys Res Commun , vol.176 , pp. 593-598
    • Minami, M.1    Kuraishi, Y.2    Satoh, M.3
  • 53
    • 0028577356 scopus 로고
    • Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures
    • Chao CC, Hu S: Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. Dev Neurosci 16:172-179, 1994.
    • (1994) Dev Neurosci , vol.16 , pp. 172-179
    • Chao, C.C.1    Hu, S.2
  • 54
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee JC, Laydon JT, McDonnell PC, et al: A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739-746, 1995.
    • (1995) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 55
    • 0027440120 scopus 로고
    • Regionally selective stimulation of mitogen activated protein (MAP) kinase tyrosine phosphorylation after generalized seizures in the rat brain
    • Gass P, Kiessling M, Bading H: Regionally selective stimulation of mitogen activated protein (MAP) kinase tyrosine phosphorylation after generalized seizures in the rat brain. Neurosci Lett 162:39-42, 1993.
    • (1993) Neurosci Lett , vol.162 , pp. 39-42
    • Gass, P.1    Kiessling, M.2    Bading, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.