Adapting clinical paradigms to the challenges of cancer clonal evolution

American Journal of Pathology

Volumn 182, Issue 6, 2013, Pages 1962-1971

  Murugaesu, Nirupa ^a   Chew, Su Kit ^a   Swanton, Charles ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; BIOLOGICAL MARKER; CARBOPLATIN; CRIZOTINIB; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; SUNITINIB;

ADVANCED CANCER; ANTINEOPLASTIC ACTIVITY; CANCER ADJUVANT THERAPY; CANCER DIAGNOSIS; CANCER RESISTANCE; CHROMOSOMAL INSTABILITY; CLONAL EVOLUTION; DIAGNOSTIC IMAGING; DISEASE COURSE; DRUG SENSITIVITY; ENVIRONMENTAL FACTOR; EPITHELIAL MESENCHYMAL TRANSITION; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; INTRATUMOR HETEROGENEITY; KIDNEY METASTASIS; MALIGNANT NEOPLASTIC DISEASE; METASTASIS; MINIMALLY INVASIVE PROCEDURE; MOLECULARLY TARGETED THERAPY; MUTATIONAL ANALYSIS; NEOPLASM; NONHUMAN; OUTCOME ASSESSMENT; PHYLOGENY; PRIORITY JOURNAL; REVIEW; SOMATIC MUTATION; TUMOR BIOPSY;

CLONAL EVOLUTION; GENETIC VARIATION; HUMANS; MUTATION; NEOPLASMS; NEOPLASTIC STEM CELLS; PHYLOGENY; RESEARCH DESIGN; TUMOR MARKERS, BIOLOGICAL; TUMOR MICROENVIRONMENT;

EID: 84878251993     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.02.026     Document Type: Review

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