How ion channels sense mechanical force: Insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2

Annals of the New York Academy of Sciences

Volumn 1352, Issue 1, 2015, Pages 20-32

  Brohawn, Stephen G ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Ion channel gating; Mechanosensation; Membrane tension; TRAAK; TREK1; TREK2

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL TRAAK; POTASSIUM CHANNEL TREK1; POTASSIUM CHANNEL TREK2; UNCLASSIFIED DRUG; KCNK10 PROTEIN, HUMAN; KCNK4 PROTEIN, HUMAN; POTASSIUM CHANNEL PROTEIN TREK-1; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ACTION POTENTIAL; ARTICLE; CELL MEMBRANE; CHANNEL GATING; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN; INTRACELLULAR SIGNALING; ION CURRENT; LIPID BILAYER; NONHUMAN; PATCH CLAMP TECHNIQUE; PHYSICAL MODEL; ANIMAL; CHEMICAL MODEL; CHEMISTRY; GENETICS; MECHANOTRANSDUCTION; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION;

ANIMALS; HUMANS; ION CHANNEL GATING; MECHANOTRANSDUCTION, CELLULAR; MODELS, CHEMICAL; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84942821878     PISSN: 00778923     EISSN: 17496632     Source Type: Journal    
DOI: 10.1111/nyas.12874     Document Type: Article

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