A phospholipid sensor controls mechanogating of the K+ channel TREK-1

EMBO Journal

Volumn 24, Issue 1, 2005, Pages 44-53

  Chemin, Jean ^a   Patel, Amanda Jane ^a   Duprat, Fabrice ^a   Lauritzen, Inger ^a   Lazdunski, Michel ^a   Honoré, Eric ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

General anesthesia; K2P; KCNK; Neuro protection; Stretch

Indexed keywords

MEMBRANE PHOSPHOLIPID; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; PROTON;

ACIDOSIS; ANIMAL CELL; ARTICLE; ATMOSPHERIC PRESSURE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL SWELLING; CHANNEL GATING; CONTROLLED STUDY; CYTOSOL; ELECTRIC POTENTIAL; GENERAL ANESTHESIA; MECHANOTRANSDUCTION; MOUSE; NEUROPROTECTION; NONHUMAN; PH; POTASSIUM CHANNEL K2P2.1; POTASSIUM CHANNEL KCNK; POTASSIUM CHANNEL TREK 1; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; PROTON TRANSPORT; SENSOR; SURFACE CHARGE;

AMINO ACID SEQUENCE; ANIMALS; BIOSENSING TECHNIQUES; CELL MEMBRANE; CELLS, CULTURED; HYDROGEN-ION CONCENTRATION; ION CHANNEL GATING; MICE; MOLECULAR SEQUENCE DATA; NEURONS; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN STRUCTURE, TERTIARY; PROTONS; RECOMBINANT FUSION PROTEINS; STRESS, MECHANICAL;

EID: 13244279466     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600494     Document Type: Article

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