Mechanoprotection by Polycystins against Apoptosis Is Mediated through the Opening of Stretch-Activated K2P Channels

Cell Reports

Volumn 1, Issue 3, 2012, Pages 241-250

  Peyronnet, Rémi ^a   Sharif Naeini, Reza ^a   Folgering, Joost H A ^a   Arhatte, Malika ^a   Jodar, Martine ^a   El Boustany, Charbel ^a   Gallian, Claire ^a   Tauc, Michel ^b   Duranton, Christophe ^b   Rubera, Isabelle ^b   Lesage, Florian ^a   Pei, York ^c   Peters, Dorien J M ^d   Somlo, Stefan ^e   Sachs, Frederick ^f   Patel, Amanda ^a   Honoré, Eric ^a   Duprat, Fabrice ^a  

^a INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ CÔTE D'AZUR   (France)

^c UNIVERSITY OF TORONTO   (Canada)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; FILAMIN A; POLYCYSTIN; POTASSIUM CHANNEL; TRAAK PROTEIN; TREK1 PROTEIN; TREK2 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELLULAR STRESS RESPONSE; CHANNEL GATING; CONTROLLED STUDY; KIDNEY CELL; MECHANICAL STRESS; MECHANOTRANSDUCTION; PROTEIN FUNCTION;

ACIDOSIS; ACTIN CYTOSKELETON; ANIMALS; APOPTOSIS; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOPROTECTION; DOCOSAHEXAENOIC ACIDS; GENE KNOCKOUT TECHNIQUES; ION CHANNEL GATING; KIDNEY TUBULES, PROXIMAL; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, KNOCKOUT; MUTANT PROTEINS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN SUBUNITS; STRESS, MECHANICAL; TRPP CATION CHANNELS;

EID: 84861166382     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2012.01.006     Document Type: Article

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