Methionine and its derivatives increase bladder excitability by inhibiting stretch-dependent K + channels

British Journal of Pharmacology

Volumn 153, Issue 6, 2008, Pages 1259-1271

  Baker, S A ^a   Hennig, G W ^a   Han, J ^a   Britton, F C ^a   Smith, T K ^a   Koh, S D ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

BK and SK channels; Bladder contractility; Ca 2+ transients; Membrane potentials; TREK 1

Indexed keywords

CALCIUM; METHIONINE; METHIONINE DERIVATIVE; METHIONINE METHYL ESER; METHIONINOL; POTASSIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; CALCIUM CONDUCTANCE; CONTROLLED STUDY; CYSTOMETRY; DRUG MECHANISM; GUINEA PIG; MONKEY; MUSCLE CELL; MUSCLE EXCITATION; NONHUMAN; PATCH CLAMP; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE;

ANIMALS; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION; GUINEA PIGS; MACACA FASCICULARIS; MALE; METHIONINE; MICE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; SPECIES SPECIFICITY; URINARY BLADDER;

EID: 40949119019     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707690     Document Type: Article

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