Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels

Journal of Biological Chemistry

Volumn 280, Issue 34, 2005, Pages 30175-30184

  Murbartián, Janet ^a   Lei, Qiubo ^a   Sando, Julianne J ^a   Bayliss, Douglas A ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CELL MEMBRANES; CURRENT DENSITY; ENZYME INHIBITION; HORMONES;

MEMBRANE POTENTIAL; PHORBOL DIBUTYRATE; PROTIEN KINASE; THYROTROPIN RELEASING HORMONE RECEPTORS (TRHR);

ENZYMES;

ALANINE; ASPARTIC ACID; BISINDOLYLMALEIMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; ENZYME ACTIVATOR; FORSKOLIN; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; OREXIN 1 RECEPTOR; PHORBOL DIBUTYRATE; POTASSIUM CHANNEL; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C INHIBITOR; PROTIRELIN RECEPTOR; SERINE;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; POTASSIUM CHANNEL TREK 1; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TRANSPORT KINETICS;

ALANINE; ANIMALS; ASPARTIC ACID; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CLONING, MOLECULAR; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FORSKOLIN; HUMANS; INDOLES; MALEIMIDES; MICE; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHORBOL 12,13-DIBUTYRATE; PHOSPHORYLATION; POTASSIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; PROTEIN BINDING; PROTEIN KINASE C; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RECEPTORS, THYROTROPIN-RELEASING HORMONE; RECOMBINANT PROTEINS; SERINE; TIME FACTORS; TRANSFECTION;

EID: 24044440422     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M503862200     Document Type: Article

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