Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation

PLoS Genetics

Volumn 11, Issue 8, 2015, Pages

  Truong, David M ^a   Hewitt, F Curtis ^a   Hanson, Joseph H ^a   Cui, Xiaoxia ^a   Lambowitz, Alan M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM; RIBOZYME; RNA POLYMERASE II; BACTERIAL PROTEIN; LTRA PROTEIN, LACTOCOCCUS LACTIS; RETROPOSON; RNA DIRECTED DNA POLYMERASE;

ARTICLE; BACTERIAL CHROMOSOME; CATALYSIS; CELL CULTURE; CELL LEVEL; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHROMOSOME SIZE; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; GENETIC SELECTION; GENETIC TRANSDUCTION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; INTRON; INTRON RETROHOMING; LACTOCOCCUS LACTIS; MAGNESIUM CELL LEVEL; NONHUMAN; NONSENSE MEDIATED MRNA DECAY; NUCLEIC ACID STRUCTURE, METABOLISM AND FUNCTION; PROTEIN EXPRESSION; RNA SPLICING; ACTIVE TRANSPORT; CELL SURVIVAL; DIRECTED MOLECULAR EVOLUTION; GENETICS; HEK293 CELL LINE; INVERTED REPEAT; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PLASMID; RETROPOSON;

ACTIVE TRANSPORT, CELL NUCLEUS; BACTERIAL PROTEINS; BASE SEQUENCE; CELL SURVIVAL; DIRECTED MOLECULAR EVOLUTION; HEK293 CELLS; HUMANS; INTRONS; INVERTED REPEAT SEQUENCES; MOLECULAR SEQUENCE DATA; NONSENSE MEDIATED MRNA DECAY; PLASMIDS; RETROELEMENTS; RNA-DIRECTED DNA POLYMERASE;

EID: 84940758288     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005422     Document Type: Article

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