Mechanism of maturase-promoted group II intron splicing

EMBO Journal

Volumn 20, Issue 24, 2002, Pages 7259-7270

  Matsuura, Manabu ^a   Noah, James W ^a   Lambowitz, Alan M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Reverse transcriptase; Ribozyme; RNA catalysis; RNA folding; RNA protein interaction

Indexed keywords

ENZYME; MATURASE; RNA; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME MODIFICATION; ENZYME STRUCTURE; INTRON; LACTOCOCCUS LACTIS; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA SPLICING;

ALDEHYDES; BASE SEQUENCE; INTRONS; IODINE; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA; RNA SPLICING; RNA-DIRECTED DNA POLYMERASE; SACCHAROMYCES CEREVISIAE PROTEINS;

LACTOCOCCUS; LACTOCOCCUS LACTIS; STREPTOCOCCUS;

EID: 0037126592     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.24.7259     Document Type: Article

References (21)

1. A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core
2. An RNA conformational change between the two chemical steps of group II self-splicing
3. A group III twintron encoding a maturase-like gene excises through lariat intermediates
4. Frequent use of the same tertiary motif by self-folding RNAs
5. Multiple tertiary interactions involving domain II of group II self-splicing introns
6. Retrohoming: cDNA-mediated mobility of a bacterial group II intron requires a catalytic RNA
7. Retrotransposition of a yeast group II intron occurs by reverse splicing directly into ectopic DNA sites
8. Nuclear mutations that block group II RNA splicing in maize chloroplasts reveal several intron classes with distinct requirements for splicing factors
9. A map of the binding site for catalytic domain 5 in the core of a group II intron ribozyme
10. Group I and group II ribozymes as RNPs: Clues to the past and guides to the future
11. A bacterial group II intron encoding reverse transcriptase, maturase, and DNA endonuclease activities: Biochemical demonstration of maturase activity and insertion of new genetic information within the intron
12. Structure and activities of group II introns
13. Evolutionary relationships among group II intron-encoded proteins and identification of a conserved domain that may be related to maturase function
14. RNA and protein catalysis in group II intron splicing and mobility reactions using purified components
15. Interaction of a group II intron ribonucleoprotein endonuclease with its DNA target site investigated by DNA footprinting and modification interference
16. Mechanical devices of the spliceosome: Motors, clocks, springs and things
17. Visualizing the solvent-inaccessible core of a group II intron ribozyme
18. Co-evolution of group II intron RNA structures with their intron-encoded reverse transcriptases
19. Comparative analysis of splicing of the complete set of chloroplast group II introns in three higher plant mutants
20. A reverse transcriptase/maturase promotes splicing by binding at its own coding segment in a group II intron RNA
21. Function and evolution of a minimal plastid genome from a nonphotosynthetic parasitic plant