Concentration, compartmentation and metabolic function of intracellular free Mg2+

Magnesium Research

Volumn 19, Issue 4, 2006, Pages 225-236

  Gunther T ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b NONE   (Germany)

Author keywords

31P NMR; Calcium; Compartmentation; Furaptra; Magnesium; Mg 2+ electrode; Second messenger

Indexed keywords

2 (2 (5 CARBOXY)OXAZOLE) 5 HYDROXY 6 AMINOBENZOFURAN N,N,O TRIACETIC ACID; 2-(2-(5-CARBOXY)OXAZOLE)-5-HYDROXY-6-AMINOBENZOFURAN-N,N,O-TRIACETIC ACID; ADENOSINE TRIPHOSPHATE; CALCIUM; DRUG DERIVATIVE; FURA 2; MAGNESIUM; UNCLASSIFIED DRUG;

ANIMAL; CELL COMPARTMENTALIZATION; CELL ORGANELLE; CYTOSOL; HUMAN; KINETICS; METABOLISM; MICROELECTRODE; NEOPLASM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REVIEW; SECOND MESSENGER;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELL COMPARTMENTATION; CYTOSOL; FURA-2; HUMANS; KINETICS; MAGNESIUM; MAGNETIC RESONANCE SPECTROSCOPY; MICROELECTRODES; NEOPLASMS; ORGANELLES; SECOND MESSENGER SYSTEMS;

EID: 33847689849     PISSN: 09531424     EISSN: None     Source Type: Journal    
DOI: 10.1684/mrh.2006.0067     Document Type: Review

References (104)

1. Ebel H, Günther T. Magnesium metabolism: A. review. J Clin Chem Clin Biochem 1980; 18: 257-70.
2. Günther T. Functional compartmentation of intracellular magnesium. In: Sigel H, Sigel A, eds. Metal ions in biological systems, Vol. 26. New York, Basel: Marcel Dekker Inc, 1990: 193-213.
3. Mota De Freitas D, Dorus E. Techniques for measuring magnesium in tissues from hypertensive, psychiatric, and neurological patients. In: Birch NJ, ed. Magnesium and the cell. London, Boston, San Diego, New York, Sydney, Tokyo: Academic Press, 1993: 51-79.
4. London RE. Methods for measurement of intracellular magnesium: NMR and fluorescence. Annu Rev Physiol 1991; 53: 241-58.
5. Murphy E. Measurement of intracellular ionized magnesium. Miner Electrolyte Metab 1993; 19: 250-8.
6. 31P-NMR spectra of ATP. Magnes Bull 2000; 22: 20-5.
7. 2+ in permeabilized smooth muscle cells with use of furaptra. Am J Physiol 1995; 269: C698-C705.
8. Günther T. Die intrazelluläre Mg-Ionenkonzentration. Z Naturforsch 1967; 22b: 149-54.
9. 2+ and the regulation of mitochondrial volume. Am J Physiol 1999; 277: C1194-C1201.
10. 2+ in isolated heart mitochondria using fluorescent probes. Magnes Trace Elem 1991-1992; 10: 151-64.
11. 2+ channel protein of Saccharomyces cerevisiae. FEBS J 2006; 273: 1198-209.
12. Sillen LG, Martell AE. Stability constants of metal-ion complexes. London: The Chemical Society Burlington House, 1971.
13. Nanninga LB. The association constant of the complexes of adenosine triphosphate with magnesium, calcium, strontium and barium ions. Biochim Biophys Acta 1961; 54: 330-8.
14. 31P NMR ionized magnesium determinations. Anal Biochem 1997; 251: 246-50.
15. 31P NMR and optical absorbance spectroscopy. Biochem Biophys Res Commun 1983; 117: 210-5.
16. Berger H, Jänig GR, Gerber G, Ruckpaul H, Rappoport SM. Interaction of haemoglobin with ions. Interactions among magnesium, adenosine 5'-triphosphate, 2,3 bis-phosphoglycerate, and oxygenated and deoxygenated human haemoglobin under simulated intracellular conditions. Eur J Biochem 1973; 38: 553-62.
17. 31P NMR. J Biol Chem 1978; 253: 6172-6.
18. 31P nuclear magnetic resonance measurement of free erythrocyte magnesium concentration in man and its relation to blood pressure. Clin Sci 1988; 74: 513-7.
19. 31P NMR chemical shifts of ATP. Anal Biochem 1993; 214: 458-67.
20. 31P-NMR. Exp Physiol 1999; 84: 231-52.
21. 2+ concentration in Xenopus muscle fibres at rest, during fatigue and during metabolic blockade. Exper Pysiol 1992; 77: 733-40.
22. Murphy E, Freudenrich CC, Levy LA, London RE, Lieberman M. Monitoring cytosolic free magnesium in cultured chicken heart cells by use of the fluorescent indicator furaptra. Proc Natl Acad Sci USA 1989; 86: 2981-4.
23. Raju B, Murphy E, Levy LA, Hall RD, London RE. A fluorescent indicator for measuring cytosolic free magnesium. J Am Physiol 1989; 256: C540-C548.
24. 2+ in cerebral vascular smooth muscle cells. Eur J Pharmacol 1993; 246: 299-301.
25. 2+ concentration in smooth muscle cells of guinea pig tenia cecum: intracellular calibration of the fluorescent indicator furaptra. Biophys J 1997; 73: 3358-70.
26. Schachter M, Gallagher KL, Sever PS. Measurement of intracellular magnesium in a vascular smooth muscle cell line using a fluorescent probe. Biochim Biophys Acta 1990; 1035: 378-80.
27. 2+ indicator furaptra in rat ventricular myocytes. Pflügers Arch Eur J Physiol 2001; 442: 35-40.
28. 3H-1 cells with mag-fura-2. Mol Cell Biochem 1994; 136: 11-22.
29. Lennard R, Singh J. Secretagogue-evoked changes in intracellular free magnesium concentrations in rat pancreatic acinar cells. J Physiol 1991; 435: 483-92.
30. Delva P, Pastori C, Degan M, Montesi G, Lechi A. Catecholamine-induced regulation in vitro and ex vivo of intralymphocyte ionized magnesium. J Membr Biol 2004; 199: 163-71.
31. 2+ concentration in mouse skeletal muscle fibers with the fluorescent indicator mag-indo-1. Biophys J 1998; 75: 957-67.
32. Resnick LM, Altura BT, Gupta RK, Laragh JH, Alderman MH, Altura BM. Intracellular and extracellular magnesium depletion in type 2 (non-insulin- dependent) diavetes mellitus. Diabetologia 1993; 36: 767-70.
33. 2+ in human erythrocytes. Biochim Biophys Acta 1990; 1035: 169-74.
34. Flatman PW. The effect of buffer composition and deoxygenation on the concentration of ionized magnesium inside human red blood cells. J Physiol 1980; 300: 19-30.
35. 2+ efflux from magnesium-deficient erythrocytes. Magnes Bull 1990; 12: 43-6.
36. 31P MRS: application to the measurement of free intracellular magnesium in vivo. MRM 1996; 35: 174-85.
37. 31P-nuclear magnetic resonance spectra. J Neurochem 1989; 53: 331-4.
38. 31P NMR in vivo. NMR Biomed 1992; 5: 53-8.
39. 31P-NMR spectroscopy. Biochim Biophys Acta 1986; 885: 1-11.
40. Desmoulin F, Cozzone PJ, Canioni P. Phosphorus-31 nuclear-magnetic- resonance study of phosphorylated metabolites compartmentation, intracellular pH and phosphorylation state during normoxia. hypoxia and ethanol perfusion, in the perfused rat liver. Eur J Biochem 1987; 162: 151-9.
41. 2+ of rabbit bladder and uterine smooth muscle. J Biol Chem 1986; 261: 14420-9.
42. Ryschon TW, Rosenstein DL, Rubinow DR, Niemela JE, Elin RJ, Balaban RS. Relationship between skeletal muscle intracellular ionized magnesium and measurements of blood magnesium. J Lab Clin Med 1996; 127: 207-13.
43. Wu ST, Pieper GM, Salhany JM, Eliot RS. Measurement of free magnesium in perfused and ischemic arrested heart muscle. A quantitative phosphorus-31 nuclear magnetic resonance and multiequilibria analysis. Biochemistry 1981; 20: 7399-403.
44. 2+ in intact frog skeletal muscle. J Biol Chem 1980; 255: 3987-93.
45. Nakayama S, Nomura H, Tomita T. Intracellular free magnesium in the smooth muscle of guinea pig taenia caeci: a concomitant analysis for magnesium and pH upon sodium removal. J Gen Physiol 1994; 103: 833-51.
46. 2+. MgATP, and MgADP in intact Ehrlich ascites tumor cells. Proc Natl Acad Sci USA 1980; 77: 2487-91.
47. 2+ with aequorin. Am J Physiol 1988; 255: H855-H859.
48. 2+ in lymphocytes. J Cell Biol 1982; 95: 189-96.
49. Lopez JR, Alamo L, Caputo C, Vergara J, DiPolo R. Direct measurement of intracellular free magnesium in frog skeletal muscle using magnesium-selective microelectrodes. Biochim Biophys Acta 1984; 804: 1-7.
50. Hess P, Metzger P, Weingart R. Free magnesium in sheep, ferret and frog striated muscle at rest measured with ion-selective micro-electrodes. J Physiol 1982; 333: 173-88.
51. 2+ concentration in skeletal muscle fibres of frog and crayfish. Pflügers Arch Eur J Physiol 1991; 417: 446-53.
52. MacDermott M. The intracellular concentration of free magnesium in extensor digitorum longus muscles of the rat. Exp Physiol 1990; 75: 763-9.
53. 2+-selective microelectrodes and fluorochromes. Exp Physiol 1993; 78: 221-33.
54. Buri A, McGuigan JAS. Intracellular free magnesium and its regulation, studied in isolated ferret ventricular muscle with ion-selective microelectrodes. Exp Physiol 1990; 75: 751-61.
55. Mooren FC, Tun S, Günzel D, Schlue W-R, Domschke W, Singh J, Lerch MM. Calcium-magnesium interactions in pancreatic acinar cells. FASEB J 2001; 15: 659-72.
56. Alvarez-Leefmans FJ, Gamino SM, Rink TJ. Intracellular free magnesium in neurones of Helix Aspersa measured with ion-selective micro-electrodes. J Physiol 1984; 354: 303-17.
57. 2+ in renal epithelial cells. Am J Physiol 1992; 262: F1100-F1104.
58. Hwang DL, Yen CF, Nadler JL. Insulin increases intracellular magnesium transport in human platelets. J Clin Endocrinol Metab 1993; 76: 549-53.
59. Takaya J, Higashino H, Miyazaki R, Kobayashi Y. Effects of insulin and insulin- like growth factor-1 on intracellular magnesium of platelets. Exp Mol Pathol 1998; 65: 104-9.
60. Touyz RM, Schiffrin EL. The effect of angiotensin II on platelet intracellular free magnesium and calcium ionic concentrations in essential hypertension. J Hypertens 1993; 11: 551-8.
61. Ng LL, Davies JE, Garrido MC. Intracellular free magnesium in human lymphocytes and the response to lectins. Clin Sci 1991; 80: 539-47.
62. 2+ concentration in single Swiss 3T3 fibroblasts. Am J Physiol 1991; 261: C1074-C1080.
63. 2+- and tyrosine kinase- dependent mechanisms. J Biochem (Tokyo) 1994; 115: 730-7.
64. 2+ pool in rat sublingual mucous acini. J Biol Chem 1992; 267: 20721-7.
65. i in vascular smooth muscle cells. Am J Physiol 1992; 263: C873-C878.
66. +-dependent protein kinase C pathways. J Biol Chem 1996; 271: 24353-8.
67. Singh J, Wisdom DM. Second messenger role of magnesium in pancreatic acinar cells of the rat. Mol Cell Biochem 1995; 149/150: 175-82.
68. Rotevatn S, Sarheim H, Murphy E. Intracellular free magnesium concentration: relevance to cardiovascular medicine. Acta Physiol Scan 1991; S599: 125-33.
69. Drakenberg T. Physical methods for studying the biological chemistry of magnesium. In: Cowan JA, ed. The Biological Chemistry of Magnesium. New York, Weinheim, Cambridge: VCH Publishers Inc., 1995: 27.
70. Stauff J, Jaenicke R. Physikalische Chemie der Lösungen. In: Rauen HM, ed. Biochemisches Taschenbuch, 2. Teil, 2. Auflage. Berlin, Göttingen, Heidelberg, New York: Springer-Verlag, 1964: S.37.
71. Reboiras MD, Pfister H, Pauly H. Activity coefficients of salts in highly concentrated protein solutions. I. Alkali chlorides in isoionic bovine serum albumin solutions. Biophys Chem 1978; 9: 37-46.
72. Altura BM, Altura BT. Role of magnesium in the pathogenesis of hypertension updated: Relationship to its actions on cardiac, vascular smooth muscle, and endothelial cells. In: Laragh JH, Brenner BM, eds. Hypertension: Pathophysiology, Diagnosis and Management, sec ed. New York: Raven Press, Ltd, 1995: 1213-42.
73. 2+ changes in a vascular smooth muscle cell line. Am J Physiol 1993; 265: H281-H288.
74. 2+ signaling in single human tracheal gland cells. Biochem Biophys Res Commun 1996; 227: 743-9.
75. Han JW, Thieleczek R, Varsanyi M, Heilmeyer Jr. LMG. Compartmentalized ATP synthesis in skeletal muscle triads. Biochemistry 1992; 31: 377-84.
76. 2+ transport. Circ Res 1995; 77: 88-97.
77. Agus ZS, Morad M. Modulation of cardiac ion channels by magnesium. Annu Rev Physiol 1991; 53: 299-307.
78. Gwanyanya A, Amuzescu B, Zakharov SI, Macianskiene R, Sipido KR, Bolotina VM, Vereecke J, Mubagwa K. Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation. J Physiol 2004; 559: 761-76.
79. Fleig A, Penner R. The TRPM ion channel subfamily: molecular, biophysical and functional features. Trends Pharmacol Sci 2004; 25: 633-9.
80. Günther T. Beiträge zur biologischen Bedeutung des Magnesiums. Habilitationsschrift FU Berlin, 1965.
81. 2+/adenine nucleotide on the observed velocity of some kinase reactions. FEBS Lett 1973; 34: 243-6.
82. 2+ and enhancing its extent of activation by guanine nucleotides. Proc Natl Acad Sci USA 1982; 79: 5179-83.
83. Günther T. Über die Rolle des Mg bei der Regulation des Zellstoffwechsels. Z Naturforsch 1966; 21b: 1174-7.
84. Laughlin MR, Thompson D. The regulatory role for magnesium in glycolytic flux of the human erythrocyte. J Biol Chem 1996; 271: 28977-83.
85. Günther T, Vormann J, Förster R. Functional compartmentation of intracellular magnesium. Magnes Bull 1984; 6: 77-81.
86. 2+ control of respiration in isolated rat liver mitochondria. Biochemistry 1996; 35: 12849-56.
87. 2+ in rat heart mitochondria J Biol Chem 1998; 273: 7850-5.
88. Vernon WB. The role of magnesium in nucleic-acid and protein metabolism. Magnesium 1988; 7: 234-48.
89. Garfinkel D, Garfinkel L. Magnesium and regulation of carbohydrate metabolism at the molecular level. Magnesium 1988; 7: 249-61.
90. Grubbs RD, Maguire ME. Magnesium as a regulatory cation: criteria and evaluation. Magnesium 1987; 6: 113-27.
91. Takaya J, Higashino H, Kobayashi Y, Can magnesium act as a second messenger? Current data on translocation induced by various biologically active substances. Magnes Res 2000; 13: 139-46.
92. Rubin H. The membrane, magnesium, mitosis (MMM) model of cell proliferation control. Magnes Res 2005; 18: 268-74.
93. Cameron IL, Smith NKR. Cellular concentration of magnesium and other ions in relation to protein synthesis, cell proliferation and cancer. Magnesium 1989; 8: 31-44.
94. Di Francesco A, Desnoyer RW, Covacci V, Wolf FI, Romani A, Cittadini A, Bond M. Changes in magnesium content and subcellular distribution during retinoic acid-induced differentiation of HL 60 cells. Arch Biochem Biophys 1998; 360: 149-57.
95. Wolf FI, Covacci V, Bruzzese N, Di Francesco A, Sacchetti A, Corda D, Cittadini A. Differentiation of HL-60 promyelocytic leukemia cells is accompanied by a modification of magnesium homeostasis. J Cell Biochem 1998; 71: 441-8.
96. Matsuno K, Koyama M, Takeda H, Abe K, Sakurada K, Miyazaki T, Kobayashi K. Cytosolic free magnesium concentration in human platelets. Thromb Res 1993; 69: 131-7.
97. 3H1 myocytes. Am J Physiol 1991; 260: C1158-C1164.
98. 2+ response amplitude and duration. Nature 1997; 386: 855-8.
99. Carafoli E. Calcium - a universal carrier of biological signals. FEBS J 2005; 272: 1073-89.
100. Freudenrich CC, Murphy E, Liu S, Lieberman M. Magnesium homeostasis in cardiac cells. Mol Cell Biochem 1992; 114: 97-103.
101. Murphy E. Mysteries of magnesium homeostasis. Circ Res 2000; 86: 245-8.
102. Rijkers GT, Griffioen AW. Changes in free cytoplasmic magnesium following activation of human lymphocytes. Biochem J 1993; 289: 373-7.
103. 2+ interactions. Ren Physiol 1994; 17: 279-86.
104. Günther T. Phylogenesis and ontogenesis of magnesium. Magnes Bull 1994; 16: 143-6.