Inhibition of calcium influx reduces dysfunction and apoptosis in lipotoxic pancreatic β-cells via regulation of endoplasmic reticulum stress

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Zhou, Yuren ^a   Sun, Peng ^a,b   Wang, Ting ^a   Chen, Kaixian ^a,b   Zhu, Weiliang ^a   Wang, Heyao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; DIAZOXIDE; NIFEDIPINE; PALMITIC ACID; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; IMMUNOFLUORESCENCE; INCUBATION TIME; INSULIN RELEASE; LIPOTOXICITY; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; STAINING; ANIMAL; CALCIUM SIGNALING; DRUG EFFECTS; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

MURINAE;

ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; DIAZOXIDE; ENDOPLASMIC RETICULUM STRESS; INSULIN-SECRETING CELLS; MICE; NIFEDIPINE; PALMITIC ACID;

EID: 84940188339     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132411     Document Type: Article

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