DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Sun, Peng ^a   Wang, Ting ^a   Zhou, Yuren ^a   Liu, Hong ^a   Jiang, Hualiang ^a   Zhu, Weiliang ^a   Wang, Heyao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; DC 260126; G PROTEIN COUPLED RECEPTOR 40; GLUCOSE; INSULIN; PROINSULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD CHEMISTRY; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC OBESITY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPERINSULINEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PANCREAS ISLET DISEASE; TREATMENT DURATION;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; IMMUNOHISTOCHEMISTRY; INSULIN-SECRETING CELLS; MALE; MICE; MICE, OBESE; RECEPTORS, G-PROTEIN-COUPLED;

MUS;

EID: 84878888184     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0066744     Document Type: Article

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