Glucose-insensitivity induced by Ca2+ toxicity in islet β-cells and its prevention by PACAP

Peptides

Volumn 23, Issue 1, 2002, Pages 135-142

  Yanagida, Kazuhiro ^a   Yaekura, Kazuro ^a   Arima, Terukatsu ^a   Yada, Toshihiko ^a,b  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Ca2+ toxicity; Cytoprotection; Cytosolic Ca2+ increase; Diabetes; Glucose insensitivity; High K+; Insulinotropin; Islet cells; PACAP; Rat pancreas

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; NIFEDIPINE; POTASSIUM ION;

AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; BIOLOGICAL MONITORING; CALCIUM CELL LEVEL; CELL CULTURE; CELL PROTECTION; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE;

ANIMALS; CALCIUM; CELLS, CULTURED; COLORING AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT DYES; FURA-2; GLUCOSE; ISLETS OF LANGERHANS; NEUROPEPTIDES; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POTASSIUM; RATS; TIME FACTORS; VASODILATOR AGENTS;

EID: 0036152631     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00589-7     Document Type: Article

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