Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens

Molecular Pharmacology

Volumn 88, Issue 2, 2015, Pages 291-303

  Cardoso, Fernanda C ^a   Dekan, Zoltan ^a   Rosengren, K Johan ^a   Erickson, Andelain ^a   Vetter, Irina ^a   Deuis, Jennifer R ^a   Herzig, Volker ^a   Alewood, Paul F ^a   King, Glenn F ^a   Lewis, Richard J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; PROTX-III PROTEIN, THRIXOPELMA PRURIENS; SCORPION VENOM; SODIUM CHANNEL NAV1.7; SPIDER VENOM; VOLTAGE GATED SODIUM CHANNEL BLOCKING AGENT;

ANIMAL; C57BL MOUSE; CHEMICAL STRUCTURE; CHEMICALLY INDUCED; CHEMISTRY; CHO CELL LINE; CLASSIFICATION; CRICETULUS; DISEASE MODEL; HEK293 CELL LINE; HUMAN; ISOLATION AND PURIFICATION; MALE; MASS SPECTROMETRY; METABOLISM; MOUSE; PAIN; SPIDER; TUMOR CELL LINE;

ANALGESICS; ANIMALS; CELL LINE, TUMOR; CHO CELLS; CRICETULUS; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; MALE; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; NAV1.7 VOLTAGE-GATED SODIUM CHANNEL; PAIN; SCORPION VENOMS; SPIDER VENOMS; SPIDERS; VOLTAGE-GATED SODIUM CHANNEL BLOCKERS;

EID: 84939790347     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.115.098178     Document Type: Article

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