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Volumn 8, Issue 6, 2013, Pages 1215-1222

Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1

Author keywords

[No Author keywords available]

Indexed keywords

SCORPION VENOM; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7;

EID: 84879761724     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400012k     Document Type: Article
Times cited : (51)

References (40)
  • 1
    • 29844433234 scopus 로고    scopus 로고
    • Overview of molecular relationships in the voltage-gated ion channel superfamily
    • Yu, F. H., Yarov-Yarovoy, V., Gutman, G. A., and Catterall, W. A. (2005) Overview of molecular relationships in the voltage-gated ion channel superfamily Pharmacol. Rev. 57, 387-395
    • (2005) Pharmacol. Rev. , vol.57 , pp. 387-395
    • Yu, F.H.1    Yarov-Yarovoy, V.2    Gutman, G.A.3    Catterall, W.A.4
  • 2
    • 84861716984 scopus 로고    scopus 로고
    • Voltage-gated sodium channels at 60: Structure, function and pathophysiology
    • Catterall, W. A. (2012) Voltage-gated sodium channels at 60: structure, function and pathophysiology J. Physiol. 590, 2577-2589
    • (2012) J. Physiol. , vol.590 , pp. 2577-2589
    • Catterall, W.A.1
  • 4
    • 33846474874 scopus 로고    scopus 로고
    • Voltage-gated sodium channel modulation by scorpion α-toxins
    • Bosmans, F. and Tytgat, J. (2007) Voltage-gated sodium channel modulation by scorpion α-toxins Toxicon 49, 142-158
    • (2007) Toxicon , vol.49 , pp. 142-158
    • Bosmans, F.1    Tytgat, J.2
  • 6
    • 33745249950 scopus 로고    scopus 로고
    • Potent modulation of the voltage-gated sodium channel Na(v)1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae
    • Maertens, C., Cuypers, E., Amininasab, M., Jalali, A., Vatanpour, H., and Tytgat, J. (2006) Potent modulation of the voltage-gated sodium channel Na(v)1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae Mol. Pharmacol. 70, 405-414
    • (2006) Mol. Pharmacol. , vol.70 , pp. 405-414
    • Maertens, C.1    Cuypers, E.2    Amininasab, M.3    Jalali, A.4    Vatanpour, H.5    Tytgat, J.6
  • 7
    • 34548476521 scopus 로고    scopus 로고
    • The roles of sodium channels in nociception: Implications for mechanisms of pain
    • Cummins, T. R., Sheets, P. L., and Waxman, S. G. (2007) The roles of sodium channels in nociception: Implications for mechanisms of pain Pain 131, 243-257
    • (2007) Pain , vol.131 , pp. 243-257
    • Cummins, T.R.1    Sheets, P.L.2    Waxman, S.G.3
  • 9
    • 1942420685 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of the α-scorpion toxin BotIII: Pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels
    • Benkhadir, K., Kharrat, R., Cestele, S., Mosbah, A., Rochat, H., El Ayeb, M., and Karoui, H. (2004) Molecular cloning and functional expression of the α-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels Peptides 25, 151-161
    • (2004) Peptides , vol.25 , pp. 151-161
    • Benkhadir, K.1    Kharrat, R.2    Cestele, S.3    Mosbah, A.4    Rochat, H.5    El Ayeb, M.6    Karoui, H.7
  • 10
    • 19744378859 scopus 로고    scopus 로고
    • Expression of the standard scorpion α-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements
    • Legros, C., Ceard, B., Vacher, H., Marchot, P., Bougis, P. E., and Martin-Eauclaire, M. F. (2005) Expression of the standard scorpion α-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements Biochim. Biophys. Acta 1723, 91-99
    • (2005) Biochim. Biophys. Acta , vol.1723 , pp. 91-99
    • Legros, C.1    Ceard, B.2    Vacher, H.3    Marchot, P.4    Bougis, P.E.5    Martin-Eauclaire, M.F.6
  • 12
    • 0027944205 scopus 로고
    • Synthesis of proteins by native chemical ligation
    • Dawson, P. E., Muir, T. W., Clark-Lewis, I., and Kent, S. B. (1994) Synthesis of proteins by native chemical ligation Science 266, 776-779
    • (1994) Science , vol.266 , pp. 776-779
    • Dawson, P.E.1    Muir, T.W.2    Clark-Lewis, I.3    Kent, S.B.4
  • 13
    • 3342903753 scopus 로고    scopus 로고
    • A one-pot total synthesis of crambin
    • Bang, D. and Kent, S. B. (2004) A one-pot total synthesis of crambin Angew. Chem., Int. Ed. 43, 2534-2538
    • (2004) Angew. Chem., Int. Ed. , vol.43 , pp. 2534-2538
    • Bang, D.1    Kent, S.B.2
  • 14
    • 38349125099 scopus 로고    scopus 로고
    • Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein
    • Durek, T., Zhang, J., He, C., and Kent, S. B. H. (2007) Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein Org. Lett. 9, 5497-5500
    • (2007) Org. Lett. , vol.9 , pp. 5497-5500
    • Durek, T.1    Zhang, J.2    He, C.3    Kent, S.B.H.4
  • 15
    • 0026486811 scopus 로고
    • In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences
    • Schnölzer, M., Alewood, P., Jones, A., Alewood, D., and Kent, S. B. (1992) In situ neutralization in Boc-chemistry solid phase peptide synthesis. Rapid, high yield assembly of difficult sequences Int. J. Pept. Protein Res. 40, 180-193
    • (1992) Int. J. Pept. Protein Res. , vol.40 , pp. 180-193
    • Schnölzer, M.1    Alewood, P.2    Jones, A.3    Alewood, D.4    Kent, S.B.5
  • 17
    • 68949137013 scopus 로고    scopus 로고
    • Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion α-toxins
    • Kahn, R., Karbat, I., Ilan, N., Cohen, L., Sokolov, S., Catterall, W. A., Gordon, D., and Gurevitz, M. (2009) Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion α-toxins J. Biol. Chem. 284, 20684-20691
    • (2009) J. Biol. Chem. , vol.284 , pp. 20684-20691
    • Kahn, R.1    Karbat, I.2    Ilan, N.3    Cohen, L.4    Sokolov, S.5    Catterall, W.A.6    Gordon, D.7    Gurevitz, M.8
  • 18
    • 84863774312 scopus 로고    scopus 로고
    • Mapping of scorpion toxin receptor sites at voltage-gated sodium channels
    • Gurevitz, M. (2012) Mapping of scorpion toxin receptor sites at voltage-gated sodium channels Toxicon 60, 502-511
    • (2012) Toxicon , vol.60 , pp. 502-511
    • Gurevitz, M.1
  • 19
    • 4143091852 scopus 로고    scopus 로고
    • Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins
    • Guan, R. J., Xiang, Y., He, X. L., Wang, C. G., Wang, M., Zhang, Y., Sundberg, E. J., and Wang, D. C. (2004) Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins J. Mol. Biol. 341, 1189-1204
    • (2004) J. Mol. Biol. , vol.341 , pp. 1189-1204
    • Guan, R.J.1    Xiang, Y.2    He, X.L.3    Wang, C.G.4    Wang, M.5    Zhang, Y.6    Sundberg, E.J.7    Wang, D.C.8
  • 20
    • 0038606006 scopus 로고    scopus 로고
    • Importance of the conserved aromatic residues in the scorpion α-like toxin BmK M1 - The hydrophobic surface region revisited
    • Sun, Y. M., Bosmans, F., Zhu, R. H., Goudet, C., Xiong, Y. M., Tytgat, J., and Wang, D. C. (2003) Importance of the conserved aromatic residues in the scorpion α-like toxin BmK M1-The hydrophobic surface region revisited J. Biol. Chem. 278, 24125-24131
    • (2003) J. Biol. Chem. , vol.278 , pp. 24125-24131
    • Sun, Y.M.1    Bosmans, F.2    Zhu, R.H.3    Goudet, C.4    Xiong, Y.M.5    Tytgat, J.6    Wang, D.C.7
  • 21
    • 84864135552 scopus 로고    scopus 로고
    • Isolation, characterization and total regioselective synthesis of the novel muO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels
    • Vetter, I., Dekan, Z., Knapp, O., Adams, D. J., Alewood, P. F., and Lewis, R. J. (2012) Isolation, characterization and total regioselective synthesis of the novel muO-conotoxin MfVIA from Conus magnificus that targets voltage-gated sodium channels Biochem. Pharmacol. 84, 540-548
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 540-548
    • Vetter, I.1    Dekan, Z.2    Knapp, O.3    Adams, D.J.4    Alewood, P.F.5    Lewis, R.J.6
  • 23
    • 32844466512 scopus 로고    scopus 로고
    • State-dependent compound inhibition of Na(v)1.2 sodium channels using the FLIPR V-m dye: On-target and off-target effects of diverse pharmacological agents
    • Benjamin, E. R., Pruthi, F., Olanrewaju, S., Ilyin, V. I., Crumley, G., Kutlina, E., Valenzano, K. J., and Woodward, R. M. (2006) State-dependent compound inhibition of Na(v)1.2 sodium channels using the FLIPR V-m dye: On-target and off-target effects of diverse pharmacological agents J. Biomol. Screening 11, 29-39
    • (2006) J. Biomol. Screening , vol.11 , pp. 29-39
    • Benjamin, E.R.1    Pruthi, F.2    Olanrewaju, S.3    Ilyin, V.I.4    Crumley, G.5    Kutlina, E.6    Valenzano, K.J.7    Woodward, R.M.8
  • 24
    • 84856073147 scopus 로고    scopus 로고
    • Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels
    • M111.012054
    • Zhu, S., Peigneur, S., Gao, B., Lu, X., Cao, C., and Tytgat, J. (2012) Evolutionary diversification of Mesobuthus α-scorpion toxins affecting sodium channels Mol. Cell. Proteomics 11 M111.012054
    • (2012) Mol. Cell. Proteomics , vol.11
    • Zhu, S.1    Peigneur, S.2    Gao, B.3    Lu, X.4    Cao, C.5    Tytgat, J.6
  • 26
    • 0242468736 scopus 로고    scopus 로고
    • Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: A new scorpion toxin that discriminates between neuronal and skeletal sodium channels
    • Alami, M., Vacher, H., Bosmans, F., Devaux, C., Rosso, J. P., Bougis, P. E., Tytgat, J., Darbon, H., and Martin-Eauclaire, M. F. (2003) Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels Biochem. J. 375, 551-560
    • (2003) Biochem. J. , vol.375 , pp. 551-560
    • Alami, M.1    Vacher, H.2    Bosmans, F.3    Devaux, C.4    Rosso, J.P.5    Bougis, P.E.6    Tytgat, J.7    Darbon, H.8    Martin-Eauclaire, M.F.9
  • 27
    • 0035050571 scopus 로고    scopus 로고
    • Resurgence of sodium channel research
    • Goldin, A. L. (2001) Resurgence of sodium channel research Annu. Rev. Physiol. 63, 871-894
    • (2001) Annu. Rev. Physiol. , vol.63 , pp. 871-894
    • Goldin, A.L.1
  • 28
    • 0033731909 scopus 로고    scopus 로고
    • Molecular mechanisms of neurotoxin action on voltage-gated sodium channels
    • Cestele, S. and Catterall, W. A. (2000) Molecular mechanisms of neurotoxin action on voltage-gated sodium channels Biochimie 82, 883-892
    • (2000) Biochimie , vol.82 , pp. 883-892
    • Cestele, S.1    Catterall, W.A.2
  • 29
    • 48649093428 scopus 로고    scopus 로고
    • α-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels
    • Campos, F. V., Chanda, B., Beirao, P. S. L., and Bezanilla, F. (2008) α-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels J. Gen. Physiol. 132, 251-263
    • (2008) J. Gen. Physiol. , vol.132 , pp. 251-263
    • Campos, F.V.1    Chanda, B.2    Beirao, P.S.L.3    Bezanilla, F.4
  • 30
    • 0030037704 scopus 로고    scopus 로고
    • Molecular determinants of high affinity binding of α-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit
    • Rogers, J. C., Qu, Y. S., Tanada, T. N., Scheuer, T., and Catterall, W. A. (1996) Molecular determinants of high affinity binding of α-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit J. Biol. Chem. 271, 15950-15962
    • (1996) J. Biol. Chem. , vol.271 , pp. 15950-15962
    • Rogers, J.C.1    Qu, Y.S.2    Tanada, T.N.3    Scheuer, T.4    Catterall, W.A.5
  • 31
    • 0032191111 scopus 로고    scopus 로고
    • Voltage sensor-trapping: Enhanced activation of sodium channels by β-scorpion toxin bound to the S3-S4 loop in domain II
    • Cestele, S., Qu, Y. S., Rogers, J. C., Rochat, H., Scheuer, T., and Catterall, W. A. (1998) Voltage sensor-trapping: Enhanced activation of sodium channels by β-scorpion toxin bound to the S3-S4 loop in domain II Neuron 21, 919-931
    • (1998) Neuron , vol.21 , pp. 919-931
    • Cestele, S.1    Qu, Y.S.2    Rogers, J.C.3    Rochat, H.4    Scheuer, T.5    Catterall, W.A.6
  • 32
    • 0036846886 scopus 로고    scopus 로고
    • Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation
    • Chanda, B. and Bezanilla, F. (2002) Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation J. Gen. Physiol. 120, 629-645
    • (2002) J. Gen. Physiol. , vol.120 , pp. 629-645
    • Chanda, B.1    Bezanilla, F.2
  • 33
    • 84859606337 scopus 로고    scopus 로고
    • Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom
    • Cologna, C. T., Peigneur, S., Rustiguel, J. K., Nonato, M. C., Tytgat, J., and Arantes, E. C. (2012) Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom FEBS J. 279, 1495-1504
    • (2012) FEBS J. , vol.279 , pp. 1495-1504
    • Cologna, C.T.1    Peigneur, S.2    Rustiguel, J.K.3    Nonato, M.C.4    Tytgat, J.5    Arantes, E.C.6
  • 34
    • 0026080931 scopus 로고
    • An antiinsect toxin purified from the scorpion Androctonus australis Hector also acts on the α-sites and β-sites of the mammalian sodium-channel - Sequence and circular-dichroism study
    • Loret, E. P., Martineauclaire, M. F., Mansuelle, P., Sampieri, F., Granier, C., and Rochat, H. (1991) An antiinsect toxin purified from the scorpion Androctonus australis Hector also acts on the α-sites and β-sites of the mammalian sodium-channel-sequence and circular-dichroism study Biochemistry 30, 633-640
    • (1991) Biochemistry , vol.30 , pp. 633-640
    • Loret, E.P.1    Martineauclaire, M.F.2    Mansuelle, P.3    Sampieri, F.4    Granier, C.5    Rochat, H.6
  • 35
    • 56249091754 scopus 로고    scopus 로고
    • Deconstructing voltage sensor function and pharmacology in sodium channels
    • Bosmans, F., Martin-Eauclaire, M. F., and Swartz, K. J. (2008) Deconstructing voltage sensor function and pharmacology in sodium channels Nature 456, 202-U228
    • (2008) Nature , vol.456
    • Bosmans, F.1    Martin-Eauclaire, M.F.2    Swartz, K.J.3
  • 36
    • 84863682656 scopus 로고    scopus 로고
    • Biophysical properties of Nav1.8/Nav1.2 chimeras and inhibition by mu O-conotoxin MrVIB
    • Knapp, O., Nevin, S. T., Yasuda, T., Lawrence, N., Lewis, R. J., and Adams, D. J. (2012) Biophysical properties of Nav1.8/Nav1.2 chimeras and inhibition by mu O-conotoxin MrVIB Br. J. Pharmacol. 166, 2148-2160
    • (2012) Br. J. Pharmacol. , vol.166 , pp. 2148-2160
    • Knapp, O.1    Nevin, S.T.2    Yasuda, T.3    Lawrence, N.4    Lewis, R.J.5    Adams, D.J.6
  • 37
    • 0033621158 scopus 로고    scopus 로고
    • Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology
    • Hackeng, T. M., Griffin, J. H., and Dawson, P. E. (1999) Protein synthesis by native chemical ligation: Expanded scope by using straightforward methodology Proc. Natl. Acad. Sci. U.S.A. 96, 10068-10073
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 10068-10073
    • Hackeng, T.M.1    Griffin, J.H.2    Dawson, P.E.3
  • 38
    • 0036460766 scopus 로고    scopus 로고
    • Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh-2 and Lqh-3
    • Chen, H. J., Lu, S. Q., Leipold, E., Gordon, D., Hansel, A., and Heinemann, S. H. (2002) Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh-2 and Lqh-3 Eur. J. Neurosci. 16, 767-770
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 767-770
    • Chen, H.J.1    Lu, S.Q.2    Leipold, E.3    Gordon, D.4    Hansel, A.5    Heinemann, S.H.6


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