The Moderately Efficient Enzyme: Futile Encounters and Enzyme Floppiness

Biochemistry

Volumn 54, Issue 32, 2015, Pages 4969-4977

  Bar Even, Arren ^a   Milo, Ron ^b   Noor, Elad ^c   Tawfik, Dan S ^b  

^a MAX PLANCK INSTITUTE OF MOLECULAR PLANT PHYSIOLOGY   (Germany)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; ECONOMIC AND SOCIAL EFFECTS; SUBSTRATES;

CATALYTIC EFFICIENCIES; CATALYTIC TURNOVER; ENZYME EVOLUTIONS; ENZYME-SUBSTRATE COMPLEXES; INHERENT FLEXIBILITY; MOLECULAR ORIGINS; PRODUCT FORMATION; RATE ACCELERATION;

ENZYMES;

ENZYME; MULTIENZYME COMPLEX;

ACCELERATION; ARTICLE; CATALYTIC EFFICIENCY; DIFFUSION; DISSOCIATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SUBSTRATE; ENZYME SYNTHESIS; KINETIC PARAMETERS; MICHAELIS CONSTANT; MOLECULAR EVOLUTION; PRIORITY JOURNAL; PROTEIN INTERACTION; RATE CONSTANT; STATIC ELECTRICITY; SUBSTRATE CONCENTRATION; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; METABOLISM; MOLECULAR DYNAMICS;

CATALYTIC DOMAIN; ENZYMES; KINETICS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; STATIC ELECTRICITY; SUBSTRATE SPECIFICITY;

EID: 84939644294     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00621     Document Type: Article

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