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Volumn 46, Issue 6, 2005, Pages 1239-1247

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

Author keywords

Arylesterase; Low density lipoprotein oxidation; N acyl homoserine lactones; Protein expression and purification

Indexed keywords

ARACHIDONIC ACID; ARYLDIALKYLPHOSPHATASE 1; COPPER; HEXANOIC ACID; ICOSATETRAENOIC ACID; MANNOSE; MEVINOLIN; ORGANOPHOSPHATE; SPIRONOLACTONE; 5 HYDROXYICOSATETRAENOIC ACID; 5-HYDROXY-6,8,11,14-EICOSATETRAENOIC ACID; ARYLDIALKYLPHOSPHATASE; DOCOSAHEXAENOIC ACID; ESTERASE; HYDROXYICOSATETRAENOIC ACID; LACTONE; LOW DENSITY LIPOPROTEIN; OXYGEN; PON1 PROTEIN, HUMAN; PON2 PROTEIN, HUMAN; PON3 PROTEIN, HUMAN; RECOMBINANT PROTEIN;

EID: 21244491480     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M400511-JLR200     Document Type: Article
Times cited : (588)

References (58)
  • 1
    • 0029937118 scopus 로고    scopus 로고
    • The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family
    • Primo-Parmo, S. L., R. C. Sorenson, J. Teiber, and B. N. La Du. 1996. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics. 33: 498-507.
    • (1996) Genomics , vol.33 , pp. 498-507
    • Primo-Parmo, S.L.1    Sorenson, R.C.2    Teiber, J.3    La Du, B.N.4
  • 5
    • 0030293198 scopus 로고    scopus 로고
    • The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
    • Davies, H. G., R. J. Richter, M. Keifer, C. A. Broomfield, J. Sowalla, and C. E. Furlong. 1996. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat. Genet. 14: 334-336.
    • (1996) Nat. Genet. , vol.14 , pp. 334-336
    • Davies, H.G.1    Richter, R.J.2    Keifer, M.3    Broomfield, C.A.4    Sowalla, J.5    Furlong, C.E.6
  • 9
    • 0042261695 scopus 로고    scopus 로고
    • Lactonase and lactonizing activities of human paraoxonase (PON1) and rabbit serum PON3
    • Teiber, J. F., D. I. Draganov, and B. N. La Du. 2003. Lactonase and lactonizing activities of human paraoxonase (PON1) and rabbit serum PON3. Biochem. Pharmacol. 66: 887-896.
    • (2003) Biochem. Pharmacol. , vol.66 , pp. 887-896
    • Teiber, J.F.1    Draganov, D.I.2    La Du, B.N.3
  • 10
    • 0034721761 scopus 로고    scopus 로고
    • Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein- associated lactonase and protects low density lipoprotein against oxidation
    • Draganov, D. I., P. L. Stetson, C. E. Watson, S. S. Billecke, and B. N. La Du. 2000. Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation. J. Biol. Chem. 275: 33435-33442.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33435-33442
    • Draganov, D.I.1    Stetson, P.L.2    Watson, C.E.3    Billecke, S.S.4    La Du, B.N.5
  • 11
    • 0345256493 scopus 로고    scopus 로고
    • Identification of paraoxonase 3 in rat liver microsomes. Purification and biochemical properties
    • Rodrigo, L., F. Gil, A. F. Hernandez, O. Lopez, and A. Pla. 2003. Identification of paraoxonase 3 in rat liver microsomes. Purification and biochemical properties. Biochem. J. 376: 261-268.
    • (2003) Biochem. J. , vol.376 , pp. 261-268
    • Rodrigo, L.1    Gil, F.2    Hernandez, A.F.3    Lopez, O.4    Pla, A.5
  • 12
    • 0037339957 scopus 로고    scopus 로고
    • Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress
    • Rosenblat, M., D. Draganov, C. E. Watson, C. L. Bisgaier, B. N. La Du, and M. Aviram. 2003. Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress. Arterioscler. Thromb. Vasc. Biol. 23: 468-474.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 468-474
    • Rosenblat, M.1    Draganov, D.2    Watson, C.E.3    Bisgaier, C.L.4    La Du, B.N.5    Aviram, M.6
  • 13
    • 0002855059 scopus 로고
    • Possible medical significance of human serum 'A-' esterases
    • E. Rainer, W. N. Aldridge, and F. C. G. Hoskin, editors. Ellis Horwood, Chichester, UK
    • Mackness, M. I. 1989. Possible medical significance of human serum 'A-' esterases. In Enzymes Hydrolysing Organophosphorus Compounds. E. Rainer, W. N. Aldridge, and F. C. G. Hoskin, editors. Ellis Horwood, Chichester, UK. 202-213.
    • (1989) Enzymes Hydrolysing Organophosphorus Compounds , pp. 202-213
    • Mackness, M.I.1
  • 14
    • 0025719481 scopus 로고
    • Characterization of cDNA clones encoding rabbit and human serum paraoxonase: The mature protein retains its signal sequence
    • Hassett, C., R. J. Richter, R. Humbert, C. Chapline, J. W. Crabb, C. J. Omiecinski, and C. E. Furlong. 1991. Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence. Biochemistry. 30: 10141-10149.
    • (1991) Biochemistry , vol.30 , pp. 10141-10149
    • Hassett, C.1    Richter, R.J.2    Humbert, R.3    Chapline, C.4    Crabb, J.W.5    Omiecinski, C.J.6    Furlong, C.E.7
  • 15
    • 0032877947 scopus 로고    scopus 로고
    • Human serum paraoxonase/arylesterase's retained hydrophobic N-terminal leader sequence associates with high density lipoproteins by binding phospholipids: Apolipoprotein A-1 stabilizes activity
    • Sorenson, R. C., C. L. Bisgaier, M. Aviram, C. Hsu, S. Billecke, and B. N. La Du. 1999. Human serum paraoxonase/arylesterase's retained hydrophobic N-terminal leader sequence associates with high density lipoproteins by binding phospholipids: apolipoprotein A-1 stabilizes activity. Arterioscler. Thromb. Vasc. Biol. 19: 2214-2225.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 2214-2225
    • Sorenson, R.C.1    Bisgaier, C.L.2    Aviram, M.3    Hsu, C.4    Billecke, S.5    La Du, B.N.6
  • 17
    • 0035976903 scopus 로고    scopus 로고
    • Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein
    • Ng, C. J., D. J. Wadleigh, A. Gangopadhyay, S. Hama, V. R. Grijalva, M. Navab, A. M. Fogelman, and S. T. Reddy. 2001. Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein. J. Biol. Chem. 276: 44444-44449.
    • (2001) J. Biol. Chem. , vol.276 , pp. 44444-44449
    • Ng, C.J.1    Wadleigh, D.J.2    Gangopadhyay, A.3    Hama, S.4    Grijalva, V.R.5    Navab, M.6    Fogelman, A.M.7    Reddy, S.T.8
  • 18
    • 0032526104 scopus 로고    scopus 로고
    • Human PON2 gene at 7q21.3: Cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence
    • Mochizuki, H., S. W. Scherer, T. Xi, D. C. Nickle, M. Majer, J. J. Huizenga, L. C. Tsui, and M. Prochazka. 1998. Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence. Gene. 213: 149-157.
    • (1998) Gene , vol.213 , pp. 149-157
    • Mochizuki, H.1    Scherer, S.W.2    Xi, T.3    Nickle, D.C.4    Majer, M.5    Huizenga, J.J.6    Tsui, L.C.7    Prochazka, M.8
  • 19
    • 0025864611 scopus 로고
    • Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein
    • Mackness, M. I., S. Arrol, and P. N. Durrington. 1991. Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein. FEBS Lett. 286: 152-154.
    • (1991) FEBS Lett. , vol.286 , pp. 152-154
    • Mackness, M.I.1    Arrol, S.2    Durrington, P.N.3
  • 20
    • 0032522985 scopus 로고    scopus 로고
    • Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase
    • Aviram, M., M. Rosenblat, C. L. Bisgaier, R. S. Newton, S. L. Primo-Parmo, and B. N. La Du. 1998. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. J. Clin. Invest. 101: 1581-1590.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1581-1590
    • Aviram, M.1    Rosenblat, M.2    Bisgaier, C.L.3    Newton, R.S.4    Primo-Parmo, S.L.5    La Du, B.N.6
  • 22
    • 0028784851 scopus 로고
    • Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein
    • Watson, A. D., J. A. Berliner, S. Y. Hama, B. N. La Du, K. F. Faull, A. M. Fogelman, and M. Navab. 1995. Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. J. Clin. Invest. 96: 2882-2891.
    • (1995) J. Clin. Invest. , vol.96 , pp. 2882-2891
    • Watson, A.D.1    Berliner, J.A.2    Hama, S.Y.3    La Du, B.N.4    Faull, K.F.5    Fogelman, A.M.6    Navab, M.7
  • 24
    • 0037639963 scopus 로고    scopus 로고
    • Functional genomic of the paraoxonase (PON1) polymorphisms: Effects on pesticide sensitivity, cardiovascular disease, and drug metabolism
    • Costa, L. G., T. B. Cole, G. P. Jarvik, and C. E. Furlong. 2003. Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annu. Rev. Med. 54: 371-392.
    • (2003) Annu. Rev. Med. , vol.54 , pp. 371-392
    • Costa, L.G.1    Cole, T.B.2    Jarvik, G.P.3    Furlong, C.E.4
  • 26
    • 0003282726 scopus 로고    scopus 로고
    • CHD and atherosclerosis: Human epidemiological studies and transgenic mouse models
    • L. G. Costa and C. E. Furlong, editors. Kluwer Academic Publishers, Norwell, MA
    • Shih, D. M., S. T. Reddy, and A. J. Lusis. 2002. CHD and atherosclerosis: human epidemiological studies and transgenic mouse models. In Paraoxonase (PON1) in Health and Disease. L. G. Costa and C. E. Furlong, editors. Kluwer Academic Publishers, Norwell, MA. 93-124.
    • (2002) Paraoxonase (PON1) in Health and Disease , pp. 93-124
    • Shih, D.M.1    Reddy, S.T.2    Lusis, A.J.3
  • 27
    • 0034978852 scopus 로고    scopus 로고
    • Baculovirus-mediated expression and purification of human serum paraoxonase 1A
    • Brushia, R. J., T. M. Forte, M. N. Oda, B. N. La Du, and J. K. Bielicki. 2001. Baculovirus-mediated expression and purification of human serum paraoxonase 1A. J. Lipid Res. 42: 951-958.
    • (2001) J. Lipid Res. , vol.42 , pp. 951-958
    • Brushia, R.J.1    Forte, T.M.2    Oda, M.N.3    La Du, B.N.4    Bielicki, J.K.5
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0001522673 scopus 로고
    • Starch-gel electrophoresis - Application to the classification of pituitary proteins and polypeptides
    • Ferguson, K. A. 1964. Starch-gel electrophoresis - application to the classification of pituitary proteins and polypeptides. Metabolism. 13: 985-1002.
    • (1964) Metabolism , vol.13 , pp. 985-1002
    • Ferguson, K.A.1
  • 30
    • 0017342164 scopus 로고
    • Molecular weights of protein multimers from polyacrylamide gel electrophoresis
    • Bryan, J. K. 1977. Molecular weights of protein multimers from polyacrylamide gel electrophoresis. Anal. Biochem. 78: 513-519.
    • (1977) Anal. Biochem. , vol.78 , pp. 513-519
    • Bryan, J.K.1
  • 31
    • 0029165744 scopus 로고
    • Comparison of purified human and rabbit serum paraoxonases
    • Kuo, C. L. and B. N. La Du. 1995. Comparison of purified human and rabbit serum paraoxonases. Drug Metab. Dispos. 23: 935-944.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 935-944
    • Kuo, C.L.1    La Du, B.N.2
  • 32
    • 0021070710 scopus 로고
    • The human serum paraoxonase/arylesterase polymorphism
    • Eckerson, H. W., C. M. Wyte, and B. N. La Du. 1983. The human serum paraoxonase/arylesterase polymorphism. Am. J. Hum. Genet. 35: 1126-1138.
    • (1983) Am. J. Hum. Genet. , vol.35 , pp. 1126-1138
    • Eckerson, H.W.1    Wyte, C.M.2    La Du, B.N.3
  • 33
    • 0024344865 scopus 로고
    • Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase
    • Furlong, C. E., R. J. Richter, S. L. Seidel, L. G. Costa, and A. G. Motulsky. 1989. Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/ arylesterase. Anal. Biochem. 180: 242-247.
    • (1989) Anal. Biochem. , vol.180 , pp. 242-247
    • Furlong, C.E.1    Richter, R.J.2    Seidel, S.L.3    Costa, L.G.4    Motulsky, A.G.5
  • 34
    • 0000704627 scopus 로고
    • Introduction of DNA into mammalian cells
    • Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, editors. John Wiley & Sons, New York
    • Kingston, R. E. 1993. Introduction of DNA into mammalian cells. In Current Protocols in Molecular Biology. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl, editors. John Wiley & Sons, New York. 9.1.1-9.1.7.
    • (1993) Current Protocols in Molecular Biology
    • Kingston, R.E.1
  • 35
    • 10044261174 scopus 로고    scopus 로고
    • Serum PON1 does not protect LDL against oxidation induced by copper and AAPH in vitro
    • Teiber, J. F., D. I. Draganov, and B. N. La Du. 2004. Serum PON1 does not protect LDL against oxidation induced by copper and AAPH in vitro. J. Lipid Res. 45: 2260-2268.
    • (2004) J. Lipid Res. , vol.45 , pp. 2260-2268
    • Teiber, J.F.1    Draganov, D.I.2    La Du, B.N.3
  • 36
    • 0031816430 scopus 로고    scopus 로고
    • Calcium binding by human and rabbit serum paraoxonases. Structural stability and enzymatic activity
    • Kuo, C. L., and B. N. La Du. 1998. Calcium binding by human and rabbit serum paraoxonases. Structural stability and enzymatic activity. Drug Metab. Dispos. 26: 653-660.
    • (1998) Drug Metab. Dispos. , vol.26 , pp. 653-660
    • Kuo, C.L.1    La Du, B.N.2
  • 40
    • 10644283921 scopus 로고    scopus 로고
    • Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite
    • Connelly, P. W., D. Draganov, and G. F. Maguire. 2005. Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite. Free Radic. Biol. Med. 38: 164-174.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 164-174
    • Connelly, P.W.1    Draganov, D.2    Maguire, G.F.3
  • 41
    • 0037423286 scopus 로고    scopus 로고
    • Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles
    • Marathe, G. K., G. A. Zimmerman, and T. M. McIntyre. 2003. Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles. J. Biol. Chem. 278: 3937-3947.
    • (2003) J. Biol. Chem. , vol.278 , pp. 3937-3947
    • Marathe, G.K.1    Zimmerman, G.A.2    McIntyre, T.M.3
  • 42
    • 0032573079 scopus 로고    scopus 로고
    • Lactone-ring-cleaving enzyme: Genetic analysis, novel RNA editing, and evolutionary implications
    • Kobayashi, M., M. Shinohara, C. Sakoh, M. Kataoka, and S. Shimizu. 1999. Lactone-ring-cleaving enzyme: genetic analysis, novel RNA editing, and evolutionary implications. Proc. Natl. Acad. Sci. USA. 95: 2787-2792.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2787-2792
    • Kobayashi, M.1    Shinohara, M.2    Sakoh, C.3    Kataoka, M.4    Shimizu, S.5
  • 43
    • 0021045568 scopus 로고
    • Lipoxygenase activity in human uterine and intrauterine tissues: New prospects for control of prostacyclin production in pre-eclampsia
    • Saeed, S. A., and M. D. Mitchell. 1983. Lipoxygenase activity in human uterine and intrauterine tissues: new prospects for control of prostacyclin production in pre-eclampsia. Clin. Exp. Hypertens. B. 2: 103-111.
    • (1983) Clin. Exp. Hypertens. B. , vol.2 , pp. 103-111
    • Saeed, S.A.1    Mitchell, M.D.2
  • 44
    • 0025217139 scopus 로고
    • Evidence for 5-lipoxygenase activity in human B cell lines. a possible role for arachidonic acid metabolites during B cell signal transduction
    • Schulam, P. G., and W. T. Shearer. 1990. Evidence for 5-lipoxygenase activity in human B cell lines. A possible role for arachidonic acid metabolites during B cell signal transduction. J. Immunol. 144: 2696-2701.
    • (1990) J. Immunol. , vol.144 , pp. 2696-2701
    • Schulam, P.G.1    Shearer, W.T.2
  • 45
    • 0023134664 scopus 로고
    • Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues
    • Haviv, F., J. D. Ratajczyk, R. W. DeNet, Y. C. Martin, R. D. Dyer, and G. W. Carter. 1987. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. J. Med. Chem. 30: 254-263.
    • (1987) J. Med. Chem. , vol.30 , pp. 254-263
    • Haviv, F.1    Ratajczyk, J.D.2    DeNet, R.W.3    Martin, Y.C.4    Dyer, R.D.5    Carter, G.W.6
  • 46
    • 0023268116 scopus 로고
    • Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11, 14-eicosatetraenoic acid analogs
    • Kerdesky, F. A. J., S. P. Schmidt, J. H. Holms, R. D. Dyer, G. W. Carter, and D. W. Brooks. 1987. Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogs. J. Med. Chem. 30: 1177-1186.
    • (1987) J. Med. Chem. , vol.30 , pp. 1177-1186
    • Kerdesky, F.A.J.1    Schmidt, S.P.2    Holms, J.H.3    Dyer, R.D.4    Carter, G.W.5    Brooks, D.W.6
  • 47
    • 0021969838 scopus 로고
    • Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages
    • Chang, J., B. Lamb, L. Marinari, A. F. Kreft, and A. J. Lewis. 1985. Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages. Eur. J. Pharmacol. 107: 215-222.
    • (1985) Eur. J. Pharmacol. , vol.107 , pp. 215-222
    • Chang, J.1    Lamb, B.2    Marinari, L.3    Kreft, A.F.4    Lewis, A.J.5
  • 48
    • 0021871816 scopus 로고
    • Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release
    • Chang, J., E. Blazek, A. F. Kreft, and A. J. Lewis. 1985. Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. Biochem. Pharmacol. 34: 1571-1575.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 1571-1575
    • Chang, J.1    Blazek, E.2    Kreft, A.F.3    Lewis, A.J.4
  • 49
    • 0029855250 scopus 로고    scopus 로고
    • Iodolactones and iodoaldehydes - Mediators of iodine in thyroid autoregulation
    • Dugrillon, A. 1996. Iodolactones and iodoaldehydes - mediators of iodine in thyroid autoregulation. Exp. Clin. Endocrinol. Diabetes. 104 (Suppl. 4): 41-45.
    • (1996) Exp. Clin. Endocrinol. Diabetes , vol.104 , Issue.4 SUPPL. , pp. 41-45
    • Dugrillon, A.1
  • 50
    • 2942545915 scopus 로고    scopus 로고
    • Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: An overview of their protective roles in catabasis
    • Serhan, C. N., K. Gotlinger, S. Hong, and M. Arita. 2004. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis. Prostaglandins Other Lipid Mediat. 73: 155-172.
    • (2004) Prostaglandins Other Lipid Mediat. , vol.73 , pp. 155-172
    • Serhan, C.N.1    Gotlinger, K.2    Hong, S.3    Arita, M.4
  • 51
    • 1642422412 scopus 로고    scopus 로고
    • Lipoxins: Potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease
    • Kieran, N. E., P. Maderna, and C. Godson. 2004. Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease. Kidney Int. 65: 1145-1154.
    • (2004) Kidney Int. , vol.65 , pp. 1145-1154
    • Kieran, N.E.1    Maderna, P.2    Godson, C.3
  • 52
    • 0031822225 scopus 로고    scopus 로고
    • A method for the determination of 5,6-EET using the lactone as an intermediate in the formation of the diol
    • Fulton, D., J. R. Falck, J. C. McGiff, M. A. Carroll, and J. Quilley. 1998. A method for the determination of 5,6-EET using the lactone as an intermediate in the formation of the diol. J. Lipid Res. 39: 1713-1721.
    • (1998) J. Lipid Res. , vol.39 , pp. 1713-1721
    • Fulton, D.1    Falck, J.R.2    McGiff, J.C.3    Carroll, M.A.4    Quilley, J.5
  • 53
    • 0032476637 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation
    • Oltman, C. L., N. L. Weintraub, M. VanRollins, and K. C. Dellsperger. 1998. Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation. Circ. Res. 83: 932-939.
    • (1998) Circ. Res. , vol.83 , pp. 932-939
    • Oltman, C.L.1    Weintraub, N.L.2    VanRollins, M.3    Dellsperger, K.C.4
  • 54
    • 4344597866 scopus 로고    scopus 로고
    • Communication blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing?
    • Roche, D. M., J. T. Byers, D. S. Smith, F. G. Glansdorp, D. R. Spring, and M. Welch. 2004. Communication blackout? Do N-acylhomoserine-lactone- degrading enzymes have any role in quorum sensing? Microbiology. 150: 2023-2028.
    • (2004) Microbiology , vol.150 , pp. 2023-2028
    • Roche, D.M.1    Byers, J.T.2    Smith, D.S.3    Glansdorp, F.G.4    Spring, D.R.5    Welch, M.6
  • 56
    • 7044222233 scopus 로고    scopus 로고
    • Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules
    • Hooi, D. S. W., B. W. Bycroft, S. R. Chhabra, P. Williams, and D. I. Pritchard. 2004. Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules. Infect. Immun. 72: 6463-6470.
    • (2004) Infect. Immun. , vol.72 , pp. 6463-6470
    • Hooi, D.S.W.1    Bycroft, B.W.2    Chhabra, S.R.3    Williams, P.4    Pritchard, D.I.5
  • 57
    • 1542723400 scopus 로고    scopus 로고
    • Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia
    • Chun, C. K., E. A. Ozer, M. J. Welsh, J. Zabner, and E. P. Greenberg. 2004. Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. Proc. Natl. Acad. Sci. USA. 101: 3587-3590.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 3587-3590
    • Chun, C.K.1    Ozer, E.A.2    Welsh, M.J.3    Zabner, J.4    Greenberg, E.P.5


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